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ARVO Annual Meeting Abstract June 2022

Preliminary Results from a First-in-human Phase I/II Gene Therapy Study (FOCUS) of Subretinally Delivered GT005, an Investigational AAV2 Vector, in Patients with Geographic Atrophy Secondary to Age-related Macular Degeneration

Jared Nielsen; Robert E MacLaren; Jeffrey S Heier; David Steel; Tsveta Ivanova; Sobha Sivaprasad; Paulo Stanga; Clare Bailey; Peter Charbel Issa; Luisa Mendonca; James Francis; Darin Curtiss; Jane Hughes; Nadia K Waheed

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1504. doi:

ARVO Annual Meeting Abstract June 2022

pRB-depleted pluripotent stem cell retinal organoids mimic retinoblastoma development

Agata Rozanska; Rodrigo Cerna-Chavez; Rachel Queen; Joseph Collin; Darin Zerti; Birthe Dorgau; Chia Shyan Beh; Tracey Davey; Jonathan Coxhead; Rafiqul Hussain; Jumana Al-Aama; David Steel; Nissim Benvenisty; Lyle Armstrong; Manoj Parulekar; Majlinda Lako

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2619. doi:

ARVO Annual Meeting Abstract June 2022

A robust, flexible retinal segmentation algorithm designed to handle neuro-degenerative disease pathology (NDD-SEG)

Rahele Kafieh; Sajed Rakhshani; Jeffry Hogg; Rachael A Lawson; Nicola Pavese; Will Innes; David H Steel; Jaume Bacardit; Jenny Read; Anya Hurlbert

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2080 – F0069. doi:

ARVO Annual Meeting Abstract June 2021

Real-life outcomes of dexamethasone intravitreal implant (Ozurdex) in diabetic macular oedema for treatment-naive eyes compared to anti-VEGF non-responders at three months post-treatment

Ali Essam Ghareeb; Tiffany Lau; Mila Kishikova; Ajay Kotagiri; Ibrahim Masri; Jonathan Smith; Deepali Varma; David Steel; Maged Habib

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1047. doi:

ARVO Annual Meeting Abstract June 2021

Functional and Structural Outcomes of Patients with Diabetic macular oedema treated with multiple Ozurdex implants at 24 months – Real Life Data

Tiffany Lau; Ali Essam Ghareeb; Mila Kishikova; Ajay Kotagiri; Ibrahim Masri; Jonathan Smith; Deepali Varma; David Steel; Maged Habib

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1046. doi:

Retina May 2021

Dissecting the Transcriptional and Chromatin Accessibility Heterogeneity of Proliferating Cone Precursors in Human Retinoblastoma Tumors by Single Cell Sequencing—Opening Pathways to New Therapeutic Strategies?

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Joseph Collin; Rachel Queen; Darin Zerti; David H Steel; Claire Bowen; Manoj Parulekar; Majlinda Lako
TAGS: chromatin, neoplasms, retinal cone, retinoblastoma, rna, small cytoplasmic, transcription, genetic, heterogeneity
Invest. Ophthalmol. Vis. Sci.. 2021; 62(6):18. doi: https://doi.org/10.1167/iovs.62.6.18

Includes: Supplemental Content

Retina January 2021

Fluorescein Angiography Findings in Eyes With Lamellar Macular Hole and Epiretinal Membrane Foveoschisis

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Roberto dell'Omo; Mariaelena Filippelli; Serena De Turris; Luca Cimino; David H. Steel; Carlos E. Pavesio; Andrea Govetto; Ismael Chehaibou; Francesco Parmeggiani; Mario R. Romano; Lucia Ziccardi; Enza Pirozzi; Ciro Costagliola
TAGS: angiogram, epiretinal membrane, eye, fluorescein angiography, macular holes, vitreous body, spectral domain-optical coherence tomography, diagnostic imaging
Invest. Ophthalmol. Vis. Sci.. 2021; 62(1):34. doi: https://doi.org/10.1167/iovs.62.1.34

Articles May 2020

microRNA Expression Profile in the Vitreous of Proliferative Diabetic Retinopathy Patients and Differences from Patients Treated with Anti-VEGF Therapy

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Julian Friedrich; David H. W. Steel; Reinier O. Schlingemann; Michael J. Koss; Hans-Peter Hammes; Guido Krenning; Ingeborg Klaassen
TAGS: micrornas, vitreous body, anti-vascular endothelial growth factor therapy
Trans. Vis. Sci. Tech.. 2020; 9(6):16. doi: https://doi.org/10.1167/tvst.9.6.16

Includes: Supplemental Content

Retina November 2019

Homozygous Variant in ARL3 Causes Autosomal Recessive Cone Rod Dystrophy

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Shakeel A. Sheikh; Robert A. Sisk; Cara R. Schiavon; Yar M. Waryah; Muhammad A. Usmani; David H. Steel; John A. Sayer; Ashok K. Narsani; Robert B. Hufnagel; Saima Riazuddin; Richard A. Kahn; Ali M. Waryah; Zubair M. Ahmed
TAGS: autosomal recessive inheritance, family, homozygote, mutation, phenotype, progressive cone-rod dystrophy, proteins, retinitis pigmentosa
Invest. Ophthalmol. Vis. Sci.. 2019; 60(14):4811-4819. doi: https://doi.org/10.1167/iovs.19-27263

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Real-life long-term outcomes for patients receiving intra-vitreal Aflibercept for neovascular age related macular degeneration (nAMD): five(5)-year follow-up

Ankur Mehta; Matthew Hartley; Majed Habib; Ajay Kotagiri; David Steel; Smith Jonathan; Deepali Varma

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):83. doi:

ARVO Annual Meeting Abstract July 2019

Predictive factors for successful treatment with intravitreal ocriplasmin

Michael Grinton; Jon Rees; Maged S Habib; Roxane Hillier; Daniela Vaideanu-Collins; Smith Jonathan; David Steel

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2008. doi:

Articles December 2018

Unintentional Movements During the Use of Vitreoretinal Forceps

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Mahmut Dogramaci; David H. Steel
TAGS: forceps, steel, surgeons, sensor
Trans. Vis. Sci. Tech.. 2018; 7(6):28. doi: https://doi.org/10.1167/tvst.7.6.28

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Real world data on the efficacy of Fluocinolone Acetonide (ILUVIEN) in eyes with diabetic macular oedema

Haifa A Madi; Yanmei Chen; David Steel; Jonathan Smith; Teresa Sandinha; Maged S Habib

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4817. doi:

ARVO Annual Meeting Abstract July 2018

Efficient generation of laminated and light responsive retinal organoids for use in toxicological assays

Dean Hallam; Gerrit Hilgen; Birthe Dorgau; Min Yu; Lili Zhu; Sanja Bojic; Philip Hewitt; Michael Schmitt; Marianne Uteng; Stefan Kustermann; David Steel; Andrew Porter; Achim Treumann; Evelyne Sernagor; Lyle Armstrong; Majlinda Lako

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5329. doi:

ARVO Annual Meeting Abstract July 2018

Defining the optimal stage for transplantation of pluripotent stem cell derived photoreceptor precursors

DARIN ZERTI; Joseph Collin; David Steel; Carla Bernadette Mellough; Evelyne Sernagor; Lyle Armstrong; Majlinda Lako

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):542. doi:

ARVO Annual Meeting Abstract July 2018

Laminin γ3 expression and its functional role during human retinal morphogenesis

Birthe Dorgau; Alex Sharpe; Majed Felemban; Dean Hallam; David Steel; Susan Lindsay; Carla Bernadette Mellough; Majlinda Lako

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):561. doi:

ARVO Annual Meeting Abstract July 2018

Human pluripotent stem cell derived retinal organoids reveal an important role for IMPG1 and CD44 in the development of photoreceptors and their synaptic connections

Majed Felemban; Birthe Dorgau; Nicola Hunt; Joseph Collin; David Steel; Susan Lindsay; Carla Bernadette Mellough; Majlinda Lako

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1984. doi:

ARVO Annual Meeting Abstract June 2017

Long-term real world outcomes in younger (under 60yrs) patients receiving anti-VEGF therapy for choridal neovascular membrane (CNVM).

Lyudmila Kishikova; Yewande Babalola; Maged S Habib; Deepali Varma; David Steel; Jonathan Smith; Maria T Sandinha; Ajay Kumar Kotagiri

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):418. doi:

ARVO Annual Meeting Abstract June 2017

Real life long term outcomes of patients receiving intra-vitreal Aflibercept for Neo-vascular age related macular degeneration (nAMD): three years follow up.

Yewande Babalola; Lyudmila Kishikova; Maged S Habib; Deepali Varma; Jonathan Smith; Maria T Sandinha; David Steel; Ajay Kotagiri

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):423. doi:

ARVO Annual Meeting Abstract June 2017

Real life experience of combined fixed-dosing and Treat and Extend protocols for intravitreal Aflibercept injections for Macular Oedema secondary to Central Retinal Vein Occlusion (CRVO)

Caspar Geenen; Karim El-Assal; David Steel; Deepali Varma; Ajay Kotagiri; Jonathan Smith; Maria T Sandinha; Maged S Habib

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3649. doi:

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Preliminary Results from a First-in-human Phase I/II Gene Therapy Study (FOCUS) of Subretinally Delivered GT005, an Investigational AAV2 Vector, in Patients with Geographic Atrophy Secondary to Age-related Macular Degeneration

pRB-depleted pluripotent stem cell retinal organoids mimic retinoblastoma development

A robust, flexible retinal segmentation algorithm designed to handle neuro-degenerative disease pathology (NDD-SEG)

Real-life outcomes of dexamethasone intravitreal implant (Ozurdex) in diabetic macular oedema for treatment-naive eyes compared to anti-VEGF non-responders at three months post-treatment

Functional and Structural Outcomes of Patients with Diabetic macular oedema treated with multiple Ozurdex implants at 24 months – Real Life Data

Dissecting the Transcriptional and Chromatin Accessibility Heterogeneity of Proliferating Cone Precursors in Human Retinoblastoma Tumors by Single Cell Sequencing—Opening Pathways to New Therapeutic Strategies?

Fluorescein Angiography Findings in Eyes With Lamellar Macular Hole and Epiretinal Membrane Foveoschisis

microRNA Expression Profile in the Vitreous of Proliferative Diabetic Retinopathy Patients and Differences from Patients Treated with Anti-VEGF Therapy

Homozygous Variant in ARL3 Causes Autosomal Recessive Cone Rod Dystrophy

Real-life long-term outcomes for patients receiving intra-vitreal Aflibercept for neovascular age related macular degeneration (nAMD): five(5)-year follow-up

Predictive factors for successful treatment with intravitreal ocriplasmin

Unintentional Movements During the Use of Vitreoretinal Forceps

Real world data on the efficacy of Fluocinolone Acetonide (ILUVIEN) in eyes with diabetic macular oedema

Efficient generation of laminated and light responsive retinal organoids for use in toxicological assays

Defining the optimal stage for transplantation of pluripotent stem cell derived photoreceptor precursors

Laminin γ3 expression and its functional role during human retinal morphogenesis

Human pluripotent stem cell derived retinal organoids reveal an important role for IMPG1 and CD44 in the development of photoreceptors and their synaptic connections

Long-term real world outcomes in younger (under 60yrs) patients receiving anti-VEGF therapy for choridal neovascular membrane (CNVM).

Real life long term outcomes of patients receiving intra-vitreal Aflibercept for Neo-vascular age related macular degeneration (nAMD): three years follow up.

Real life experience of combined fixed-dosing and Treat and Extend protocols for intravitreal Aflibercept injections for Macular Oedema secondary to Central Retinal Vein Occlusion (CRVO)

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