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ARVO Annual Meeting Abstract June 2025

Mechanism of glutathionylation-induced heat precipitation of γS-crystallin

Kirsten J Lampi; David Thorn; Kate Halverson-Kolkind; Larry David

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1277.

ARVO Annual Meeting Abstract June 2025

The thermodynamic cost of domain-swapping in long-lived γ-crystallins and the evolution of durable transparency in the human eye lens

David Thorn; Eugene Serebryany; Gabriel Birrane; Aidan Grosas; Ali Kaya; Constance Kraay; Amir Bitran; John Carver; Eugene Shakhnovich

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):3269.

ARVO Annual Meeting Abstract June 2024

Deamidation increases the rate of disulfide bond scrambling in glutathionylated γS-crystallin

Kirsten J Lampi; Kate Halverson-Kolkind; David Thorn; Larry L David

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):OD47.

ARVO Annual Meeting Abstract June 2024

Disulfide shuffling protects γS-crystallin from oxidative aggregation and facilitates its role as a redox sink

David Thorn; Eugene Serebryany; Kirsten J Lampi; Larry L David; Eugene Shakhnovich

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5027.

ARVO Annual Meeting Abstract June 2023

Playing “redox hot potato”: disulfide transfer between γ-crystallins in the aging, pre-cataractous lens

David Thorn; Eugene Serebryany; Larry L David; Kirsten J Lampi; Eugene Shakhnovich

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1230.

ARVO Annual Meeting Abstract June 2022

Structure and stability of domain-swapped mutant γ-crystallins: implications for lens cataract and βγ-crystallin evolution

David C Thorn; Eugene Serebryany; Gabriel Birrane; Ali Kaya; Eugene Shakhnovich

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2376 – A0060.

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