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Meeting Abstract (62)
Journal Articles (3)

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Investigative Ophthalmology & Visual Science (65)

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ARVO Annual Meeting Abstract (62)
Lens (3)

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Eye Anatomy and Disorders (3)
Lens (3)
Genetics (1)

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lens (device) (3)
lens, crystalline (3)
cattle (2)
epithelial cells (2)
proteins (2)
apoptosis (1)
cellular senescence (1)
life span (1)
mitogen-activated protein kinases (1)
oryctolagus cuniculus (1)

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ARVO Annual Meeting Abstract June 2024

Oxidative stress-induced BRD4 Promotes STING Expression and Inflammation

xiangyu ge; ming zou; qin ke; xingfei zhu; Wei Liu; David W Li; Lili Gong

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):569.

ARVO Annual Meeting Abstract June 2024

The BRD4 inhibitor JQ1 promotes autophagy-dependent clearance of cytosolic DNA and inhibits retinal inflammation

xingfei zhu; ming zou; qin ke; Wei Liu; David W Li; Lili Gong

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):568.

ARVO Annual Meeting Abstract June 2024

The BET PROTAC dBET6 inhibits retinal macrophages/microglia reactivity and reactive gliosis in response to light damage

Haifeng Cui; xingfei zhu; Wei Liu; David W Li; Lili Gong

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1669.

ARVO Annual Meeting Abstract June 2023

Light damage induces inflammatory factors in mouse vitreous humor

xiangyu ge; wei liu; xingfei zhu; yulin chen; David W Li; Lili Gong

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4883.

ARVO Annual Meeting Abstract June 2023

αA-Crystallin Interacts with TBK1 to Modulate NF-κB Pathway in Mediating Stress-Induced Changes of the Immune Microenvironment and Inflammatory Responses in the Ocular Lens

David W Li; Min Hou; Qian Nie; Jing-Miao Wang; Shuyu Zheng; Yan Wang; Jialing Fu; LAN ZHANG; Xuebin Hu; yuan xiao; Xingmiao Liang; yuwen gan

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5117.

ARVO Annual Meeting Abstract June 2023

AlphaA-Crystallin Suppresses DBC1, A Negative Regulator of SIRT1 to Repress Stress-Induced Apoptosis of Lens Epithelial Cells

Yan Wang; Jialing Fu; Shuyu Zheng; Jingmiao Wang; yuan xiao; LAN ZHANG; Xuebin Hu; yuwen gan; Xingmiao Liang; David W Li

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):526.

ARVO Annual Meeting Abstract June 2023

S133A-CREB Acts As A Novel Transcription Factor to Regulate EMT in Lens Epithelial Cells

LAN ZHANG; Xuebin Hu; yuan xiao; Yueyue Bai; Jialing Fu; Yan Wang; Shuyu Zheng; Jingmiao Wang; yuwen gan; Xingmiao Liang; David W Li

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1947.

ARVO Annual Meeting Abstract June 2023

cGAS-STING signaling is activated in retinal macrophages/microglia in response to light damage

Lili Gong; xingfei zhu; Wei Liu; David W Li

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2958.

ARVO Annual Meeting Abstract June 2023

Enhanced retinal degeneration and inflammation in Zmpest24 knockout mice in response to light damage

wei liu; xingfei zhu; xiangyu ge; David W Li; Lili Gong

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2951.

ARVO Annual Meeting Abstract June 2023

MYPT1 Dephosphorylates HMGA1a to Regulates p53-Mediated Apoptosis in Zebrafish Retina and Lens

Xuebin Hu; LAN ZHANG; Jialing Fu; Yan Wang; Shuyu Zheng; Jingmiao Wang; yuan xiao; Xinmiao Liang; yuwen gan; David W Li

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3638.

ARVO Annual Meeting Abstract June 2023

The BET PROTAC inhibitor dBET6 protects against light-induced retinal degeneration by inhibiting retinal inflammation

xingfei zhu; wei liu; xiangyu ge; yulin chen; David W Li; Lili Gong

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3502.

ARVO Annual Meeting Abstract June 2023

HSP90β Regulates Cell Proliferation through Interaction with the charged multivesicular body protein 4B (CHMP4B), A Novel Client Protein

Jialing Fu; Shuyu Zheng; Yan Wang; Jingmiao Wang; yuan xiao; LAN ZHANG; Xuebin Hu; yuwen gan; Xingmiao Liang; David W Li

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4134.

ARVO Annual Meeting Abstract June 2023

AlphaA-Crystallin Modulates cGAS/STING Pathway to Regulate the Immune Microenvironment in the Ocular Lens

Shuyu Zheng; Jialing Fu; Yan Wang; Jingmiao Wang; yuan xiao; LAN ZHANG; Xuebin Hu; yuwen gan; Xingmiao Liang; David W Li

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4133.

ARVO Annual Meeting Abstract June 2023

HSP90β Regulates the Inflammatory Response of the Ocular Lens through the NF-kB Pathway

Jingmiao Wang; Jialing Fu; Yan Wang; Shuyu Zheng; LAN ZHANG; Xuebin Hu; yuan xiao; Xingmiao Liang; yuwen gan; David W Li

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4132.

ARVO Annual Meeting Abstract June 2022

Sumoylated Pax6 Regulates Lens Stalk Regression During Lens Development

David W Li; Jialing Fu; Fangyuan Liu; Shuyu Zheng; Yan Wang; Jingmiao Wang; yuan xiao; Jiawen Xiang; Yuwen Gan; Xingmiao Liang

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):836.

ARVO Annual Meeting Abstract June 2022

Inhibition of cGAS-STING by JQ1 alleviates oxidative stress-induced retina inflammation and degeneration

Lili Gong; Ming Zou; qin ke; Ruili Qi; xingfei zhu; wei liu; David W Li

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):795 – F0354.

ARVO Annual Meeting Abstract June 2022

The cAMP Response Element Binding Protein (CREB) Negatively Regulates Pax6 Expression in Lens Epithelial Cells through Its Direct Binding to the Core Promoter of Pax6 Gene

Ling Wang; Jialing Fu; Yan Wang; Shuyu Zheng; yuan xiao; Jingmiao Wang; Jiawen Xiang; David W Li

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):661 – F0016.

ARVO Annual Meeting Abstract June 2022

The SP Family Transcription Factors Act As Major Regulators in the Transcription of the Major Heat Shock Protein, HSP90β in lens epithelial cells

Jialing Fu; Jingmiao Wang; yuan xiao; Yan Wang; Shuyu Zheng; Jiawen Xiang; Yuwen Gan; Xingmiao Liang; David W Li

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):651 – F0006.

ARVO Annual Meeting Abstract June 2022

Developmental Expression of the cGAs/STING Pathway Signal Components during Development of Mouse Lens

Shuyu Zheng; Yan Wang; Jialing Fu; Jingmiao Wang; yuan xiao; Ling Wang; Jiawen Xiang; David W Li

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):646 – F0001.

ARVO Annual Meeting Abstract June 2022

Cytosolic DNA accumulated in senescent retinal and retinal pigment epithelium cells promotes inflammatory response.

xingfei zhu; Ruili Qi; qin ke; Wei Liu; David W Li; Lili Gong

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2475 – F0182.

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