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ARVO Annual Meeting Abstract July 2019

Disease mechanisms elucidated by genetic regulation of human RPE gene expression

Douglas Vollrath; Boxiang Liu; Melissa A Calton; Nathan S. Abell; Gillie Benchorin; Michael J. Gloudemans; Ming Chen; Jane Hu; Xin Li; Brunilda Balliu; Dean Bok; Stephen B. Montgomery

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1759.

ARVO Annual Meeting Abstract July 2019

Retinoid recycling is impaired in Stargardt iPSC-derived RPE

Roxana A Radu; Nermin Kady; Jane Hu; Jacqueline Pei; Marcia Lloyd; Dean Bok; Michael B Gorin; Saravanan Karumbayaram; Anna Matynia

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2343.

ARVO Annual Meeting Abstract July 2018

Complement C5 Inhibition as a Potential Treatment for Autosomal Recessive Stargardt Disease (STGD1): Design of a Clinical Trial Assessing a Novel Treatment and Primary Outcome Measure

Karl G Csaky; Dean Bok; Roxana A. Radu; Srinivas R. Sadda

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1569.

ARVO Annual Meeting Abstract July 2018

Characterization of Stargardt iPSC-derived RPE cells

Nermin Kady; Anna Matynia; Saravanan Karumbayaram; Jane Hu; Marcia Lloyd; Dean Bok; Michael B Gorin; Roxana A. Radu

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3045.

ARVO Annual Meeting Abstract July 2018

Localization of ABCA4 in the Retinal Pigment Epithelium and its implications for Stargardt Disease

Tamara Lee Lenis; Sze Yin Ng; Jane Hu; Zhichun Jiang; Marcia Lloyd; Nicholas Esposito; Dean Bok; Silvia C Finnemann; Gabriel H Travis; Roxana A. Radu

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4502.

ARVO Annual Meeting Abstract July 2018

Genetic Ablation of Cytokine Signaling Inhibitor SOCS3 Promotes Photoreceptor Survival in Mouse Models of Retinitis Pigmentosa

Yanjie Wang; Kun-Do Rhee; Steven Nusinowitz; Dean Bok; Xian-Jie Yang

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3943.

ARVO Annual Meeting Abstract June 2017

Expression of ABCA4 in Retinal Pigment Epithelium cells and its implications for Stargardt disease

Tamara L Lenis; Shanta Sarfare; Jane Hu; Zhichun Jiang; Marcia Lloyd; Dean Bok; Gabriel H Travis; Roxana A Radu

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):607.

ARVO Annual Meeting Abstract September 2016

Peropsin Effects Light-dependent Modulation of Retinyl Esters in the RPE

Jeremy D Cook; Eunice Ng; Marcia Lloyd; Shannan Eddington; Dean Bok; Hui Sun; Roxana A Radu; Gabriel H Travis

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1736.

ARVO Annual Meeting Abstract September 2016

Elucidating the role of Retinal Pigment Epithelium (RPE)-specific ABCA4 in Stargardt disease

Tamara Lee Lenis; Zhichun Jiang; Shanta Sarfare; Andrew Le; Shannan Eddington; Dean Bok; Robert S Molday; Steven Nusinowitz; Michael Redmond; Gabriel H Travis; Roxana A Radu

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3177.

ARVO Annual Meeting Abstract September 2016

Complement reactivity in Stargardt macular degeneration

Jane Coffman; Gayle J T Pauer; Stephanie A Hagstrom; Mary E Rayborn; Joe G Hollyfield; Dean Bok; Vera L Bonilha; Roxana A Radu

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6592.

ARVO Annual Meeting Abstract June 2015

Characterization of the Cfh-/-Abca4-/- mouse model

Roxana A Radu; Zhichun Jiang; Jane Hu; Marcia Lloyd; Steven Nusinowitz; Dean Bok

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4655.

ARVO Annual Meeting Abstract June 2015

Low temperature-dependent functional rescue of RPE65 mutants associated with retinal degeneration

Minghao Jin; Songhua Li; Jane Hu; Robin J. Jin; Samuel G Jacobson; Dean Bok

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5455.

ARVO Annual Meeting Abstract April 2014

PSMD13 Promotes Degradation of Disease-Causing RPE65s via the Ubiquitin-Proteasome Pathway

Songhua Li; Tadahide Izumi; Jane Hu; Samuel G Jacobson; Dean Bok; Minghao Jin

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3475.

Letters to the Editor December 2013

Understanding RPE Lipofuscin

PDF

Janet R. Sparrow; John E. Dowling; Dean Bok
TAGS: comprehension, lipofuscin
Invest. Ophthalmol. Vis. Sci.. 2013; 54(13):8325-8326. https://doi.org/10.1167/iovs.13-13214

ARVO Annual Meeting Abstract June 2013

FGF2 mediated inhibition of epithelial-to-mesenchyme transitions in cultured human fetal RPE

Monte Radeke; Carolyn Radeke; Aaron Newman; Jane Hu; Dean Bok; Lincoln Johnson; Peter Coffey

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):1178.

ARVO Annual Meeting Abstract June 2013

LONG-TERM PROTECTION BY COMPLEMENT REGULATORY PROTEIN CRRY IN A MOUSE MODEL OF LIPOFUSCIN-MEDIATED RETINAL DEGENERATION

Shanta Sarfare; Anita Kim; Zhichun Jiang; Marcia Lloyd; Shannan Eddington; Samer Habib; Dean Bok; Steven Nusinowitz; Gabriel Travis; Roxana Radu

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):2728.

ARVO Annual Meeting Abstract June 2013

CNTF-mediated Neuroprotection in a Mouse Model of Retinitis Pigmentosa Promotes Outer Segment Elongation and Requires Cytokine Receptor gp130 Initially in Müller Glial Cells

Kun Do Rhee; Dean Bok; Steven Nusinowitz; Kevin Chao; Xian-Jie Yang

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):1270.

Biochemistry and Molecular Biology May 2012

Retinoid Content, Visual Responses, and Ocular Morphology Are Compromised in the Retinas of Mice Lacking the Retinol-Binding Protein Receptor, STRA6

PDF

Alberto Ruiz; Manuel Mark; Hugues Jacobs; Muriel Klopfenstein; Jane Hu; Marcia Lloyd; Samer Habib; Chinatsu Tosha; Roxana A Radu; Norbert B Ghyselinck; Steven Nusinowitz; Dean Bok
TAGS: mice, retina, retinoids, vitamin a, eye, retinol binding proteins, retinal pigment epithelium, language morphology, morphology, body tissue
Invest. Ophthalmol. Vis. Sci.. 2012; 53(6):3027-3039. https://doi.org/10.1167/iovs.11-8476

Includes: Multimedia, Supplemental Content

ARVO Annual Meeting Abstract March 2012

Integration, Survival and Function of Transplanted RPE Stem Cells into Mouse Models of Geographic Atrophy

C Nathaniel Roybal; Shanta S. Sarfare; Cindy X. Ruan; Jane Hu; Samer Habib; Jun Kong; Guoping Fan; Steven Nusinowitz; Dean Bok; Gabriel H. Travis

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):6889.

ARVO Annual Meeting Abstract April 2011

A Novel Approach To RPE Transplant In Mouse Models

C Nathaniel Roybal; Cindy X. Ruan; Kendal Kernstein; Chinatsu Tosha; Dean Bok; Steven Nusinowitz; Gabriel H. Travis

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):4022.

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Disease mechanisms elucidated by genetic regulation of human RPE gene expression

Retinoid recycling is impaired in Stargardt iPSC-derived RPE

Complement C5 Inhibition as a Potential Treatment for Autosomal Recessive Stargardt Disease (STGD1): Design of a Clinical Trial Assessing a Novel Treatment and Primary Outcome Measure

Characterization of Stargardt iPSC-derived RPE cells

Localization of ABCA4 in the Retinal Pigment Epithelium and its implications for Stargardt Disease

Genetic Ablation of Cytokine Signaling Inhibitor SOCS3 Promotes Photoreceptor Survival in Mouse Models of Retinitis Pigmentosa

Expression of ABCA4 in Retinal Pigment Epithelium cells and its implications for Stargardt disease

Peropsin Effects Light-dependent Modulation of Retinyl Esters in the RPE

Elucidating the role of Retinal Pigment Epithelium (RPE)-specific ABCA4 in Stargardt disease

Complement reactivity in Stargardt macular degeneration

Characterization of the Cfh-/-Abca4-/- mouse model

Low temperature-dependent functional rescue of RPE65 mutants associated with retinal degeneration

PSMD13 Promotes Degradation of Disease-Causing RPE65s via the Ubiquitin-Proteasome Pathway

Understanding RPE Lipofuscin

FGF2 mediated inhibition of epithelial-to-mesenchyme transitions in cultured human fetal RPE

LONG-TERM PROTECTION BY COMPLEMENT REGULATORY PROTEIN CRRY IN A MOUSE MODEL OF LIPOFUSCIN-MEDIATED RETINAL DEGENERATION

CNTF-mediated Neuroprotection in a Mouse Model of Retinitis Pigmentosa Promotes Outer Segment Elongation and Requires Cytokine Receptor gp130 Initially in Müller Glial Cells

Retinoid Content, Visual Responses, and Ocular Morphology Are Compromised in the Retinas of Mice Lacking the Retinol-Binding Protein Receptor, STRA6

Integration, Survival and Function of Transplanted RPE Stem Cells into Mouse Models of Geographic Atrophy

A Novel Approach To RPE Transplant In Mouse Models

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