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Meeting Abstract (71)
Journal Articles (4)

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Investigative Ophthalmology & Visual Science (75)

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ARVO Annual Meeting Abstract (71)
Retina (2)
Physiology and Pharmacology (1)
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Eye Anatomy and Disorders (4)
Retina (3)
Biochemistry and Molecular Biology (2)
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age-related macular degeneration (1)
cannabinoid receptors (1)
cannabinoids (1)
conjunctiva (1)
conjunctival epithelium (1)
crystallins (1)
cyclic amp (1)
diabetes mellitus (1)
epithelial to mesenchymal transition (1)
erythropoietin (1)

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ARVO Annual Meeting Abstract June 2025

Dysregulation of mTOR signalling in the RPE causes EMT-like changes leading to AMD-like pathology

Sridhar Bammidi; Sayan Ghosh; Olivia Chowdhury; Pooja Gautam; Vishnu Suresh Babu; Stacey L Hose; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):721.

ARVO Annual Meeting Abstract June 2025

Betaine/mTORC1-mediated activation of lipid biosynthesis in the retinal pigment epithelium (RPE) from a mouse model of dry age-related macular degeneration

Pooja Gautam; Sayan Ghosh; Peng Shang; Ruchi Sharma; Victoria Koontz; Emma Mahally; Olivia Chowdhury; Haitao Liu; Dhivyaa Rajasundaram; Stacey L Hose; Kapil Bharti; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):731.

ARVO Annual Meeting Abstract June 2025

Divergent molecular mechanisms of telomerase and shelterin in age-related macular degeneration

Vishnu Suresh Babu; PUJA DUTTA; Sridhar Bammidi; Sayan Ghosh; Pooja Gautam; Stacey L Hose; Arkasubhra Ghosh; Kapil Bharti; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):734.

ARVO Annual Meeting Abstract June 2025

Deciphering Cellular and Molecular Heterogeneity in the Retinal Pigment Epithelium (RPE) using Multiomics Analysis: The Role of Age and Smoke Exposure.

Krishna Singh; Yang Jin; Isabella Palazzo; Marisol Cano; Tongyun Liu; Debasish Sinha; Seth Blackshaw; Jiang Qian; James T Handa

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1300.

ARVO Annual Meeting Abstract June 2025

Distinct astrocyte clusters lacking βA3/A1-crystallin drive abnormal vascular remodeling

PUJA DUTTA; Sayan Ghosh; Vishnu Suresh Babu; Ying Xin; Sridhar Bammidi; Pooja Gautam; Stacey L Hose; Jiang Qian; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1275.

ARVO Annual Meeting Abstract June 2025

Apicobasal polarity is essential to retinal pigmented epithelium structure and is controlled by Pard3.

Peri Sohnen; Peng Shang; Satinder Kaur; Mehak Vohra; Simran Kumar; Sudha Swamynathan; Amanda Garces; Sheila Adams; Tomonori Hirose; Debasish Sinha; Shivalingappa K Swamynathan

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):3061.

ARVO Annual Meeting Abstract June 2024

Stimulator of interferon genes (STING) as a therapeutic target for atrophic age-related macular degeneration

Pooja Gautam; Sayan Ghosh; Victoria Koontz; Sridhar Bammidi; Stacey L Hose; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):759.

ARVO Annual Meeting Abstract June 2024

Monoclonal Antibody Development for Lipocalin-2 Neutralization in Atrophic AMD

Mihir Nemani; Emma Mahally; Sayan Ghosh; Victoria Koontz; Stacey L Hose; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):752.

ARVO Annual Meeting Abstract June 2024

Role of IL-17A in driving inflammatory responses in progression of dry age-related macular degeneration

Sayan Ghosh; Victoria Koontz; Sridhar Bammidi; Pooja Gautam; Stacey L Hose; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):737.

ARVO Annual Meeting Abstract June 2024

Dysregulated natural killer cells mediate RPE dysfunction in early Age-Related Macular Degeneration

Archana Padmanabhan Nair; Sayan Ghosh; Praveen Machiraju; Swaminathan Sethu; Debasish Sinha; Arkasubhra Ghosh

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):570.

ARVO Annual Meeting Abstract June 2024

The influence of gut microbiome on inflammatory changes in the ocular environment is triggered by the peripheral immune system

Victoria Koontz; Sayan Ghosh; Sridhar Bammidi; Pooja Gautam; Stacey L Hose; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1685.

ARVO Annual Meeting Abstract June 2024

Pard3 controls the retinal pigmented epithelial apical-basal polarity, structure, and function

Peri Sohnen; Peng Shang; Satinder Kaur; Sudha Swamynathan; Simran Kumar; Tomonori Hirose; Debasish Sinha; Shivalingappa K Swamynathan

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1316.

ARVO Annual Meeting Abstract June 2024

Linking mitochondrial dysfunction to inflammation during the progression of atrophic age-related macular degeneration

Shruti Dhar; Victoria Koontz; Sridhar Bammidi; Mihir Nemani; Pooja Gautam; Stacey L Hose; Debasish Sinha; Sayan Ghosh

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2566.

ARVO Annual Meeting Abstract June 2024

Elevated mTORC1 and mTORC2 signaling in the retinal pigmented epithelium alters glucose metabolism, leading to a pathology resembling age-related macular degeneration

Sridhar Bammidi; Olivia Chowdhury; Sayan Ghosh; Victoria Koontz; Mihir Nemani; Stacey L Hose; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2103.

ARVO Annual Meeting Abstract June 2023

Akt2 signaling in RPE contributes to retinal fibrosis in DR

Haitao Liu; Vishnu Maddipatla; Sayan Ghosh; Victoria Koontz; Stacey L Hose; J. Samuel Zigler Jr.; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):498.

ARVO Annual Meeting Abstract June 2023

Role of apicobasal polarity in retinal pigmented epithelial cells evaluated by ablation of Pard3

Peri Sohnen; Peng Shang; Satinder Kaur; Sudha Swamynathan; Tomonori Hirose; Debasish Sinha; Shivalingappa Swamynathan

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2978.

ARVO Annual Meeting Abstract June 2023

SIRT5/Akt2 signaling axis regulates TFEB activity and autophagy in the RPE cells: Implications in dry age-related macular degeneration

Sayan Ghosh; Victoria Koontz; Mihir Nemani; Olivia Chowdhury; Haitao Liu; Stacey L Hose; J. Samuel Zigler Jr.; James T Handa; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5389.

ARVO Annual Meeting Abstract June 2022

The Role of the STING/Type I IFN Signaling Pathway in Diabetic Retinopathy

Haitao Liu; Anastasiia Strizhakova; Stacey L Hose; Chao Huang; Pamela Strassburger; Gabriella Widmer; Alan D Proia; Eleonora Lad; Peter Westenskow; Nikolaos Mitrousis; Derrick Feenstra; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):413.

ARVO Annual Meeting Abstract June 2022

The differential role of distinct astrocyte populations in Persistent Fetal Vasculature (PFV) disease

Victoria Koontz; Sayan Ghosh; Nadezda A Stepicheva; Haitao Liu; PENG SHANG; Olivia Chowdhury; Anastasiia Strizhakova; Rachel Daley; Stacey L Hose; J. Samuel Zigler; Meysam Yazdankhah; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):266 – F0311.

ARVO Annual Meeting Abstract June 2022

Peroxisomal β-oxidation deficiency in RPE leads to progressive RPE dedifferentiation and retinal degeneration

Sai Kocherlakota; Yannick Das; Danielle Swinkels; Debasish Sinha; Frédéric Vaz; Marc Fransen; Myriam Baes

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):869.

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