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ARVO Annual Meeting Abstract July 2018

Measuring and Modulating Lipid Handling Pathways in the RPE: Implications for Age-Related Macular Degeneration

Jason Miller; Feriel Presswalla; Qitao Zhang; David N Zacks; Debra A Thompson

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4032. doi:

ARVO Annual Meeting Abstract June 2017

Automated Quantification of Subcellular Structures in the RPE: Lipid Droplets, Autophagic Vacuoles, and Lipofuscin

Feriel K. Presswalla; Qitao Zhang; David N Zacks; Debra A Thompson; Jason Miller

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1041. doi:

ARVO Annual Meeting Abstract June 2017

Lipid Handling by RPE Predicts Certain Features of Age-Related Macular Degeneration

Qitao Zhang; Feriel K. Presswalla; David N Zacks; Debra A Thompson; Jason Miller

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2293. doi:

ARVO Annual Meeting Abstract June 2017

Hyperautophagy in response to protein misfolding contributes to photoreceptor cell death in Pro23His-rhodopsin mice

Jingyu Yao; Lin Jia; Eric Frontera; Naheed Khan; Debra A Thompson; David N Zacks

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2487. doi:

ARVO Annual Meeting Abstract September 2016

Mertk-mediated phagocytosis inhibits the inflammatory response to TLR4 activation in a novel microglial cell line exhibiting temperature-induced quiescence and differentiation

Sumathi Shanmugam; Dejuan Kong; Debra A Thompson; Steven F Abcouwer

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2234. doi:

ARVO Annual Meeting Abstract September 2016

A primary retinal pigment epithelial culture model for evaluating therapeutic targets in dry macular degeneration

Qitao Zhang; Feriel Presswalla; Carol Charniga; Jeffrey Stern; Sally Temple; David N Zacks; Debra A Thompson; Jason Miller

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5015. doi:

ARVO Annual Meeting Abstract June 2015

Evaluating Retinal Pigment Epithelium Cultures for Establishing Automated, Live-Cell Tracking of Outer Segment Degradation

Jason Miller; Qitao Zhang; Steve Rowe; Daniel Peisach; David N Zacks; Sami Barmada; Debra A Thompson

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4225. doi:

ARVO Annual Meeting Abstract June 2015

Dose-response effect of RPE65 gene therapy on retinoid levels and correlation with clinical rescue in Rpe65-deficient dogs.

Freya Mowat; Kecia L Feathers; Alexander J Smith; Debra A Thompson; Simon M Petersen-Jones; James W B Bainbridge; Robin R Ali

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2064. doi:

Review February 2015

Advancing Therapeutic Strategies for Inherited Retinal Degeneration: Recommendations From the Monaciano Symposium

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Debra A. Thompson; Robin R. Ali; Eyal Banin; Kari E. Branham; John G. Flannery; David M. Gamm; William W. Hauswirth; John R. Heckenlively; Alessandro Iannaccone; K. Thiran Jayasundera; Naheed W. Khan; Robert S. Molday; Mark E. Pennesi; Thomas A. Reh; Richard G. Weleber; David N. Zacks; for the Monaciano Consortium
TAGS: gene therapy, retinal degeneration, universities, transplantation, comprehension, retinal dystrophies
Invest. Ophthalmol. Vis. Sci.. 2015; 56(2):918-931. doi: 10.1167/iovs.14-16049

Retinal Cell Biology May 2014

Circadian and Noncircadian Modulation of Autophagy in Photoreceptors and Retinal Pigment Epithelium

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Jingyu Yao; Lin Jia; Shameka J. Shelby; Anna M. Ganios; Kecia Feathers; Debra A. Thompson; David N. Zacks
TAGS: autophagy, photoreceptors, mice, retina, retinal pigment epithelium
Invest. Ophthalmol. Vis. Sci.. 2014; 55(5):3237-3246. doi: 10.1167/iovs.13-13336

ARVO Annual Meeting Abstract April 2014

MERTK Interactions with Src Family Kinases in the Retinal Pigment Epithelium

Anna Ganios; Shameka J Shelby; Kecia L Feathers; Lin Jia; Debra A Thompson

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):401. doi:

ARVO Annual Meeting Abstract April 2014

Autophagy in the retinal pigment epithelium: Insights into age-related macular degeneration

Jingyu Yao; Lin Jia; Naheed W Khan; Cheng-mao Lin; Joshua L Dunaief; Michael E Boulton; Daniel Klionsky; Jun-Lin Guan; Debra A Thompson; David N Zacks

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):4560. doi:

ARVO Annual Meeting Abstract April 2014

Targeting aging: Geroprotective Drug Metformin Reduces Risk of Adult-onset Open-angle Glaucoma

Julia E Richards; Hsien-Chang Lin; Bin Nan; Nidhi Talwar; David Childers; Paula Anne Newman-Casey; Debra A Thompson; Joshua D Stein; BI

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1668. doi:

ARVO Annual Meeting Abstract March 2012

Transcriptional Control of the Human RPE65 Promoter

Kecia L. Feathers; Cameron R. Strong; Sarah J. Garnai; Debra A. Thompson

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):3343. doi:

ARVO Annual Meeting Abstract March 2012

AAV-mediated Expression Of Human Rdh12 in Mouse Retina

Debra A. Thompson; Lin Jia; Jingyu Yao; Kecia L. Feathers; Selina A. Azam; Alexander J. Smith; Robin R. Ali

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):1916. doi:

ARVO Annual Meeting Abstract April 2011

Mertk-Mediated Phospho-tyrosine Signaling in the Retinal Pigment Epithelium

Shameka J. Shelby; Kecia L. Feathers; Debra A. Thompson

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):3351. doi:

ARVO Annual Meeting Abstract April 2011

Adjunctive XIAP Anti-apoptotic Therapy in PDEβ Gene-replacement Therapy in the Retinal Degeneration 10 (rd10) Mouse

Jingyu Yao; Lin Jia; Naheed Khan; Garrett Grahek; Ashley Moncrief; William W. Hauswirth; Debra A. Thompson; David N. Zacks

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):3398. doi:

ARVO Annual Meeting Abstract April 2011

The Roles of RDH8 and RDH12 In The Clearance Of All-Trans Retinal In Rod Photoreceptors

Yiannis Koutalos; Chunhe Chen; Debra A. Thompson

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):3648. doi:

Retina March 2008

Nrl -Knockout Mice Deficient in Rpe65 Fail to Synthesize 11- cis Retinal and Cone Outer Segments

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Kecia L. Feathers; Arkady L. Lyubarsky; Naheed W. Khan; Karen Teofilo; Anand Swaroop; David S. Williams; Edward N. Pugh, Jr; Debra A. Thompson
TAGS: retinal cone, retinoids, eye, mice
Invest. Ophthalmol. Vis. Sci.. 2008; 49(3):1126-1135. doi: 10.1167/iovs.07-1234

Retina April 2007

The Phenotype of Early-Onset Retinal Degeneration in Persons with RDH12 Mutations

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Andreas Schuster; Andreas R. Janecke; Robert Wilke; Eduard Schmid; Debra A. Thompson; Gerd Utermann; Bernd Wissinger; Eberhart Zrenner; Andreas Gal
TAGS: phenotype, mutation, retinal cone, electroretinography, retinal degeneration
Invest. Ophthalmol. Vis. Sci.. 2007; 48(4):1824-1831. doi: 10.1167/iovs.06-0628

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Measuring and Modulating Lipid Handling Pathways in the RPE: Implications for Age-Related Macular Degeneration

Automated Quantification of Subcellular Structures in the RPE: Lipid Droplets, Autophagic Vacuoles, and Lipofuscin

Lipid Handling by RPE Predicts Certain Features of Age-Related Macular Degeneration

Hyperautophagy in response to protein misfolding contributes to photoreceptor cell death in Pro23His-rhodopsin mice

Mertk-mediated phagocytosis inhibits the inflammatory response to TLR4 activation in a novel microglial cell line exhibiting temperature-induced quiescence and differentiation

A primary retinal pigment epithelial culture model for evaluating therapeutic targets in dry macular degeneration

Evaluating Retinal Pigment Epithelium Cultures for Establishing Automated, Live-Cell Tracking of Outer Segment Degradation

Dose-response effect of RPE65 gene therapy on retinoid levels and correlation with clinical rescue in Rpe65-deficient dogs.

Advancing Therapeutic Strategies for Inherited Retinal Degeneration: Recommendations From the Monaciano Symposium

Circadian and Noncircadian Modulation of Autophagy in Photoreceptors and Retinal Pigment Epithelium

MERTK Interactions with Src Family Kinases in the Retinal Pigment Epithelium

Autophagy in the retinal pigment epithelium: Insights into age-related macular degeneration

Targeting aging: Geroprotective Drug Metformin Reduces Risk of Adult-onset Open-angle Glaucoma

Transcriptional Control of the Human RPE65 Promoter

AAV-mediated Expression Of Human Rdh12 in Mouse Retina

Mertk-Mediated Phospho-tyrosine Signaling in the Retinal Pigment Epithelium

Adjunctive XIAP Anti-apoptotic Therapy in PDEβ Gene-replacement Therapy in the Retinal Degeneration 10 (rd10) Mouse

The Roles of RDH8 and RDH12 In The Clearance Of All-Trans Retinal In Rod Photoreceptors

Nrl -Knockout Mice Deficient in Rpe65 Fail to Synthesize 11- cis Retinal and Cone Outer Segments

The Phenotype of Early-Onset Retinal Degeneration in Persons with RDH12 Mutations

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