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Clinical Trials December 2024

A New Approach to Retinal Oxygen Extraction Measurement Based on Laser Speckle Flowgraphy and Retinal Oximetry

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Viktoria Pai; Patrick Janku; Theresa Lindner; Ulrich Graf; Leopold Schmetterer; Gerhard Garhöfer; Doreen Schmidl
TAGS: lasers, oximetry, oxygen, oxygen extraction, oxygen saturation measurement, vascular flow, hypoxia, inspiration, respiration, hyperoxia
Trans. Vis. Sci. Tech.. 2024; 13(12):12. https://doi.org/10.1167/tvst.13.12.12

ARVO Annual Meeting Abstract June 2024

Assessment of safety, tolerability and efficacy of RP501 eye drops in patients with dry eye disease and subjects wearing contact lenses with lens discomfort

Gerhard Garhofer; Theresa Lindner; Viktoria Pai; Patrick Janku; Ulf Björklund; Doreen Schmidl

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2970.

Retina March 2024

The Impact of Photopigment Bleaching on the Human Rod Photoreceptor Subretinal Space Measured Via Optical Coherence Tomography

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Alina Messner; Valentin Aranha dos Santos; Stefan Puchner; Hannes Stegmann; Andreas Schlatter; Doreen Schmidl; Rainer Leitgeb; Leopold Schmetterer; René M. Werkmeister
TAGS: optical coherence tomography, rod photoreceptors, retina, dark adaptation, light adaptation
Invest. Ophthalmol. Vis. Sci.. 2024; 65(3):20. https://doi.org/10.1167/iovs.65.3.20

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ARVO Annual Meeting Abstract June 2023

A new approach for measuring retinal oxygen extraction based on laser speckle flowgraphy and retinal oximetry

Anton B Hommer; Viktoria Pai; Patrick Janku; Theresa Lindner; Liudmyla Pylypenko; Leopold Schmetterer; Gerhard Garhofer; Doreen Schmidl

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4738.

ARVO Annual Meeting Abstract June 2023

Retinal oxygen metabolism and neuro-vascular coupling in patients with type II diabetes at different stages of diabetic retinopathy

Nikolaus Hommer; Doreen Schmidl; Martin Kallab; Andreas Schlatter; Kinga Howorka; René Werkmeister; Leopold Schmetterer; Gerhard Garhofer

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):572.

ARVO Annual Meeting Abstract June 2023

Impaired retinal oxygen metabolism and perfusion are accompanied by plasma protein and lipid alterations in recovered COVID-19 patients

Gerhard Garhofer; Doreen Schmidl; Andrea Bileck; Victoria Kauer; Leopold Schmetterer; Christopher Gerner

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1991.

ARVO Annual Meeting Abstract June 2023

Focal structure-function correlation using capillary density and retinal nerve fiber layer thickness in primary open-angle glaucoma

Martin Kallab; Nikolaus Hommer; Andreas Schlatter; Jacqueline Chua; Bingyao Tan; Doreen Schmidl; Cornelia Hirn; Oliver Findl; Leopold Schmetterer; Damon Wong; Gerhard Garhofer

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3765.

ARVO Annual Meeting Abstract June 2022

Altered retinal oxygen metabolism in patients with multiple sclerosis

Gerhard Garhofer; Martin Kallab; Nikolaus Hommer; Andreas Schlatter; Gabriel Bsteh; Patrick Altmann; Martin Pfister; René Marcel Werkmeister; Doreen Schmidl; Leopold Schmetterer

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2476 – F0183.

ARVO Annual Meeting Abstract June 2022

The effect of antibiotic eye drops on the nasal and pharyngeal microbiome in healthy subjects

Anton B Hommer; Gerhard Garhofer; Markus Zeitlinger; Alina Nussbaumer-Proell; Ingeborg Klymiuk; Slave Trajanoski; Doreen Schmidl

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2124 – F0140.

ARVO Annual Meeting Abstract June 2022

The effect of azithromycin eye drops or oral doxycycline on tear film thickness in patients with Meibomian gland dysfunction

Doreen Schmidl; Andreas Schlatter; Nikolaus Hommer; Martin Kallab; Hannes Stegmann; Kristina Zeller; Stefan Palkovits; Oliver Findl; René Marcel Werkmeister; Leopold Schmetterer; Gerhard Garhofer

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2117 – F0133.

ARVO Annual Meeting Abstract June 2021

Shear-stress dependent viscous properties of hyaluronic-based lubricants

Doreen Schmidl; Gerhard Garhofer; Leopold Schmetterer

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):729.

ARVO Annual Meeting Abstract June 2021

Orally administered dronabinol increases retinal blood flow without altering oxygen extraction in healthy subjects

Anton B Hommer; Nikolaus Hommer; Doreen Schmidl; Martin Kallab; Martin Bauer; René Werkmeister; Leopold Schmetterer; Marihan Abensperg-Traun; Gerhard Garhofer

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):549.

ARVO Annual Meeting Abstract June 2021

Effect of topical oestradiol eye drops on signs and symptoms of dry eye disease in post-menopausal women

Gerhard Garhofer; Leopold Schmetterer; Martin Vidaeus; Hans Ageland; Doreen Schmidl

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1235.

Articles June 2020

Repeatability and Reproducibility of Total Retinal Blood Flow Measurements Using Bi-Directional Doppler OCT

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Stephan Szegedi; Nikolaus Hommer; Martin Kallab; Stefan Puchner; Doreen Schmidl; René M. Werkmeister; Gerhard Garhöfer; Leopold Schmetterer
TAGS: optical coherence tomography, vascular flow
Trans. Vis. Sci. Tech.. 2020; 9(7):34. https://doi.org/10.1167/tvst.9.7.34

ARVO Annual Meeting Abstract June 2020

Retinal blood flow and neurovascular coupling in patients with Alzheimer’s disease and mild cognitive impairment

Doreen Schmidl; Stephan Szegedi; Peter Dal-Bianco; Elisabeth Stögmann; Tatjana Traub-Weidinger; Michael Rainer; Andreas Masching; Rene Marcel Werkmeister; Jacqueline Chua; Leopold Schmetterer; Gerhard Garhofer

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1739.

Physiology and Pharmacology February 2020

Changes in Retinal Blood Flow in Response to an Experimental Increase in IOP in Healthy Participants as Assessed With Doppler Optical Coherence Tomography

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Stefan Puchner; Doreen Schmidl; Laurin Ginner; Marco Augustin; Rainer Leitgeb; Stephan Szegedi; Kristina Stjepanek; Nikolaus Hommer; Martin Kallab; René Marcel Werkmeister; Leopold Schmetterer; Gerhard Garhofer
TAGS: homeostasis, intraocular pressure, optical coherence tomography, suction drainage, vascular flow
Invest. Ophthalmol. Vis. Sci.. 2020; 61(2):33. https://doi.org/10.1167/iovs.61.2.33

Physiology and Pharmacology July 2019

Age-Related Decline of Retinal Oxygen Extraction in Healthy Subjects

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Ahmed M. Bata; Klemens Fondi; Stephan Szegedi; Gerold C. Aschinger; Anton Hommer; Doreen Schmidl; Jacqueline Chua; René M. Werkmeister; Gerhard Garhöfer; Leopold Schmetterer
TAGS: metabolism, oxygen, oxygen extraction, retinal ganglion cells, retinal nerve fiber layer, vascular flow, oxygen saturation measurement
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):3162-3169. https://doi.org/10.1167/iovs.18-26234

ARVO Annual Meeting Abstract July 2019

Modeling of retinal blood flow based on fundus photos in healthy subjects

Leopold Schmetterer; Jacqueline Chua; Rene Marcel Werkmeister; Doreen Schmidl; Miao Li Chee; Ching-Yu Cheng; Tien Yin Wong; Gerhard Garhofer

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4749.

ARVO Annual Meeting Abstract July 2019

Retinal oxygen extraction is altered in patients with primary open angle glaucoma

Anton B Hommer; Doreen Schmidl; Klemens Fondi; Ahmed Bata; Rene Marcel Werkmeister; Gerhard Garhofer; Leopold Schmetterer

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5621.

ARVO Annual Meeting Abstract July 2019

Measurement of flicker induced hyperemia in the retina and optic nerve head by Laser Speckle Flowgraphy

Doreen Schmidl; Klemens Fondi; Ahmed Bata; Nikolaus Luft; Katarzyna Witkowska; René M Werkmeister; Leopold Schmetterer; Gerhard Garhofer

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5729.

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A New Approach to Retinal Oxygen Extraction Measurement Based on Laser Speckle Flowgraphy and Retinal Oximetry

Assessment of safety, tolerability and efficacy of RP501 eye drops in patients with dry eye disease and subjects wearing contact lenses with lens discomfort

The Impact of Photopigment Bleaching on the Human Rod Photoreceptor Subretinal Space Measured Via Optical Coherence Tomography

A new approach for measuring retinal oxygen extraction based on laser speckle flowgraphy and retinal oximetry

Retinal oxygen metabolism and neuro-vascular coupling in patients with type II diabetes at different stages of diabetic retinopathy

Impaired retinal oxygen metabolism and perfusion are accompanied by plasma protein and lipid alterations in recovered COVID-19 patients

Focal structure-function correlation using capillary density and retinal nerve fiber layer thickness in primary open-angle glaucoma

Altered retinal oxygen metabolism in patients with multiple sclerosis

The effect of antibiotic eye drops on the nasal and pharyngeal microbiome in healthy subjects

The effect of azithromycin eye drops or oral doxycycline on tear film thickness in patients with Meibomian gland dysfunction

Shear-stress dependent viscous properties of hyaluronic-based lubricants

Orally administered dronabinol increases retinal blood flow without altering oxygen extraction in healthy subjects

Effect of topical oestradiol eye drops on signs and symptoms of dry eye disease in post-menopausal women

Repeatability and Reproducibility of Total Retinal Blood Flow Measurements Using Bi-Directional Doppler OCT

Retinal blood flow and neurovascular coupling in patients with Alzheimer’s disease and mild cognitive impairment

Changes in Retinal Blood Flow in Response to an Experimental Increase in IOP in Healthy Participants as Assessed With Doppler Optical Coherence Tomography

Age-Related Decline of Retinal Oxygen Extraction in Healthy Subjects

Modeling of retinal blood flow based on fundus photos in healthy subjects

Retinal oxygen extraction is altered in patients with primary open angle glaucoma

Measurement of flicker induced hyperemia in the retina and optic nerve head by Laser Speckle Flowgraphy

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