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Journal Articles (7)
Meeting Abstract (7)

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Investigative Ophthalmology & Visual Science (14)

Article Type

ARVO Annual Meeting Abstract (7)
Physiology and Pharmacology (5)
Retina (2)

Topics

Eye Anatomy and Disorders (6)
Genetics (3)
Retina (3)
Biochemistry and Molecular Biology (2)
Visual Neuroscience (2)
Glaucoma (1)
Pharmacology (1)

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retinal ganglion cells (3)
caspase-3 (2)
cell volume (2)
cyclic gmp (2)
mice (2)
nitric oxide (2)
pentazocine (2)
soluble guanylyl cyclase (2)
trabecular meshwork (2)
wounds and injuries (2)

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Retina August 2021

Sigma-1R Protects Retinal Ganglion Cells in Optic Nerve Crush Model for Glaucoma

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Linya Li; Shaoqing He; Yang Liu; Thomas Yorio; Dorette Z. Ellis
TAGS: caspase-3, glaucoma, mice, optic nerve, pentazocine, retinal ganglion cells, wounds and injuries
Invest. Ophthalmol. Vis. Sci.. 2021; 62(10):17. https://doi.org/10.1167/iovs.62.10.17

ARVO Annual Meeting Abstract June 2020

Novel small hybrid molecule with cytoprotective and IOP lowering activity

Suchismita Acharya; Courtney Weston; Dorette Z Ellis; Adnan Dibas

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2721.

ARVO Annual Meeting Abstract July 2019

Retinal Ganglion Cell Losses in an Optic Nerve Crush Model Correlate with Time-Dependent Up-Regulation in phosphorylated c-Jun, c-Jun and Caspase 3.

Dorette Z Ellis; Linya Li; Yang Liu; Shaoqing He; Thomas Yorio

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):50.

Retina July 2019

Hybrid Compound SA-2 is Neuroprotective in Animal Models of Retinal Ganglion Cell Death

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Dorota L. Stankowska; Adnan Dibas; Linya Li; Wei Zhang; Vignesh R. Krishnamoorthy; Sai H. Chavala; Tam Phung Nguyen; Thomas Yorio; Dorette Z. Ellis; Suchismita Acharya
TAGS: animal model, electroretinography, eye, mice, neuroprotection, retina, retinal ganglion cells, wounds and injuries, hypoxia, ischemia
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):3064-3073. https://doi.org/10.1167/iovs.18-25999

ARVO Annual Meeting Abstract July 2018

Activation of Sigma-1 Receptor Restores Retinal Ganglion Cell Losses in Optic Nerve Crush Model for Glaucoma.

Dorette Z Ellis; Linya Li; Yang Liu; Shaoqing He; Thomas Yorio

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5296.

ARVO Annual Meeting Abstract July 2018

Bi-functional small molecule for glaucomatous optic neuropathy

Suchismita Acharya; Dorota L Stankowska; Renuka Makarand Chaphalkar; Linya Li; Dorette Z Ellis; Kytai T Nguyen; Thomas Yorio

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5298.

ARVO Annual Meeting Abstract June 2017

Activation of Sigma-1 Receptor Protects Retinal Ganglion Cell Loss in Optic Nerve Crush Model for Glaucoma

Dorette Z Ellis; Linya Li; Shaoqing He; Yang Liu; Thomas Yorio

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):212.

Physiology and Pharmacology May 2017

Sigma-1 Receptor Regulates Mitochondrial Function in Glucose- and Oxygen-Deprived Retinal Ganglion Cells

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Dorette Z. Ellis; Linya Li; Yong Park; Shaoqing He; Brett Mueller; Thomas Yorio
TAGS: caspase-3, cytochrome c oxidase, glucose, mitochondria, oxygen, retinal ganglion cells, protein overexpression, pentazocine
Invest. Ophthalmol. Vis. Sci.. 2017; 58(5):2755-2764. https://doi.org/10.1167/iovs.16-19199

ARVO Annual Meeting Abstract September 2016

Over Expression of Sigma-1 Receptor Protects Against Retinal Ganglion Cell loss in an Optic Nerve Crush Model

Dorette Z Ellis; Linya Li; Yang Liu; Yong H Park; Thomas Yorio

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):85.

ARVO Annual Meeting Abstract June 2015

Sigma-1 Receptor Increases Mitochondrial Membrane Potential in Glucose and Oxygen deprived Retinal Ganglion Cells.

Dorette Z Ellis; Linya Li; Yong H Park; Brett H Mueller; Hai-Ying Ma; Thomas Yorio; North Texas Eye Research Institute

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4258.

Physiology and Pharmacology November 2010

Endogenous Regulation of Human Schlemm's Canal Cell Volume by Nitric Oxide Signaling

PDF

Dorette Z. Ellis; Najam A. Sharif; William M. Dismuke
TAGS: cell volume, nitric oxide, schlemm's canal, deet, signal transduction, regulation
Invest. Ophthalmol. Vis. Sci.. 2010; 51(11):5817-5824. https://doi.org/10.1167/iovs.09-5072

Physiology and Pharmacology July 2009

Human Trabecular Meshwork Cell Volume Decrease by NO-Independent Soluble Guanylate Cyclase Activators YC-1 and BAY-58-2667 Involves the BK Ca Ion Channel

PDF

William M. Dismuke; Najam A. Sharif; Dorette Z. Ellis
TAGS: cell volume, cyclic gmp, ion channels, soluble guanylyl cyclase, transcriptional activation, trabecular meshwork
Invest. Ophthalmol. Vis. Sci.. 2009; 50(7):3353-3359. https://doi.org/10.1167/iovs.08-3127

Physiology and Pharmacology April 2009

Characterization of Soluble Guanylate Cyclase in NO-Induced Increases in Aqueous Humor Outflow Facility and in the Trabecular Meshwork

PDF

Dorette Z. Ellis; William M. Dismuke; Binna M. Chokshi
TAGS: soluble guanylyl cyclase, aqueous humor, trabecular meshwork
Invest. Ophthalmol. Vis. Sci.. 2009; 50(4):1808-1813. https://doi.org/10.1167/iovs.08-2750

Physiology and Pharmacology October 2001

Carbachol and Nitric Oxide Inhibition of Na,K-ATPase Activity in Bovine Ciliary Processes

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Dorette Z. Ellis; James A. Nathanson; Jason Rabe; Kathleen J. Sweadner
TAGS: adenosine triphosphatases, carbachol, cattle, cyclic gmp, nitric oxide, ouabain
Invest. Ophthalmol. Vis. Sci.. 2001; 42(11):2625-2631.

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Online ISSN: 1552-5783

Investigative Ophthalmology & Visual Science
Journal of Vision
Translational Vision Science & Technology

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