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ARVO Annual Meeting Abstract June 2020

Regulation and role of clusterin, a secretory chaperone protein, on intraocular pressure

Avinash Soundararajan; Joshua William Buzzard; Haarika Reddy; Min Hyung Kang; Douglas J Rhee; Padmanabhan P Pattabiraman

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3208. doi:

ARVO Annual Meeting Abstract June 2020

Collagen binding site in SPARC is required for chaperone activity

Brian James Liu; Caroline Christina Sachse; Min Hyung Kang; Douglas J Rhee

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1010. doi:

Glaucoma March 2020

TGFβ2-Hepcidin Feed-Forward Loop in the Trabecular Meshwork Implicates Iron in Glaucomatous Pathology

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Ajay Ashok; Suman Chaudhary; Alexander E. Kritikos; Min H. Kang; Dallas McDonald; Douglas J. Rhee; Neena Singh
TAGS: hepcidin, iron, trabecular meshwork, cattle, glaucoma, feedforward, up-regulation (physiology)
Invest. Ophthalmol. Vis. Sci.. 2020; 61(3):24. doi: https://doi.org/10.1167/iovs.61.3.24

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Clusterin-Cathepsin K Signaling in Trabecular Meshwork Outflow Pathway Regulates Intraocular Pressure

Padmanabhan P Pattabiraman; Sai Supriya Vuda; Jaeyoung Heo; Haarika Reddy; Carol B Toris; Douglas J Rhee

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5157. doi:

ARVO Annual Meeting Abstract July 2019

Glycosylation of SPARC is Critical for Binding to Extracellular Matrix Proteins and Protection from Matrix Metalloproteinase Degradation

Nathaniel Fox; Brian Liu; Kurt Scavelli; Alexandra Castillejos; Min Hyung Kang; Douglas J Rhee

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5150. doi:

ARVO Annual Meeting Abstract July 2019

Adenoviral Gene Transfer of TGF-β2 Upregulates Intraocular Pressure through SPARC and Integrin-Linked Kinase in Mice

Jaeyoung Heo; Emily Ahadizadeh; Yuxi Zheng; Min Hyung Kang; Douglas J Rhee

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5156. doi:

ARVO Annual Meeting Abstract July 2019

Suppression of SPARC in human trabecular meshwork cells upregulates Plasminogen Activator Inhibitor-1

William MacDonald; Min Hyung Kang; Douglas J Rhee

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5141. doi:

ARVO Annual Meeting Abstract July 2018

Variability of tensile strength during microsurgical knot construction: A comparative study of polyglactin 910 and lactomer suture

Abayomi Fabunmi; Douglas Rhee

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):486. doi:

ARVO Annual Meeting Abstract July 2018

TGF-β2 upregulates the extracellular proteins through SPARC and Integrin-Linked Kinase in Human Trabecular Meshwork

Jaeyoung Heo; Emily Ahadizadeh; Min Hyung Kang; Yuxi Zheng; Douglas J Rhee

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3529. doi:

Glaucoma February 2018

Testosterone Pathway Genetic Polymorphisms in Relation to Primary Open-Angle Glaucoma: An Analysis in Two Large Datasets

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Jessica N. Cooke Bailey; Puya Gharahkhani; Jae H. Kang; Mariusz Butkiewicz; David A. Sullivan; Robert N. Weinreb; Hugues Aschard; R. Rand Allingham; Allison Ashley-Koch; Richard K. Lee; Sayoko E. Moroi; Murray H. Brilliant; Gadi Wollstein; Joel S. Schuman; John H. Fingert; Donald L. Budenz; Tony Realini; Terry Gaasterland; William K. Scott; Kuldev Singh; Arthur J. Sit; Robert P. Igo, Jr; Yeunjoo E. Song; Lisa Hark; Robert Ritch; Douglas J. Rhee; Douglas Vollrath; Donald J. Zack; Felipe Medeiros; Thasarat S. Vajaranant; Daniel I. Chasman; William G. Christen; Margaret A. Pericak-Vance; Yutao Liu; Peter Kraft; Julia E. Richards; Bernard A. Rosner; Michael A. Hauser; Jamie E. Craig; Kathryn P. Burdon; Alex W. Hewitt; David A. Mackey; Jonathan L. Haines; Stuart MacGregor; Janey L. Wiggs; Louis R. Pasquale; for the Australian and New Zealand Registry of Advanced Glaucoma (ANZRAG) Consortium
TAGS: genes, glaucoma, metabolism, open-angle glaucoma, testosterone, polymorphism
Invest. Ophthalmol. Vis. Sci.. 2018; 59(2):629-636. doi: https://doi.org/10.1167/iovs.17-22708

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

Suppression of Parvin-a in Human Trabecular Meshwork Downregulates Extracellular Matrix Components

Alexandra Goulart Castillejos; Min Hyung Kang; Douglas J Rhee

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3493. doi:

ARVO Annual Meeting Abstract September 2016

Aging changes in aqueous humor dynamics and ocular biometrics of SPARC null mice

Sruthi Sampathkumar; Yuxi Zheng; Min Hyung Kang; Douglas J Rhee; Carol B Toris

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6427. doi:

ARVO Annual Meeting Abstract September 2016

Suppression of Integrin-Linked Kinase in Human Trabecular Meshwork Alters SPARC’s Effect on Extracellular Matrix and Intraocular Pressure

Emily Niloufar Ahadizadeh; Min Hyung Kang; Douglas J Rhee

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5626. doi:

ARVO Annual Meeting Abstract September 2016

Suppression of thrombospondin-1 (TSP1) in Human Trabecular Meshwork Alters Extracellular Matrix

Min Hyung Kang; Douglas J Rhee

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6024. doi:

ARVO Annual Meeting Abstract September 2016

Treatment with AICAR decreases intraocular pressure in perfused ex vivo human anterior segments

Ayan Chatterjee; Guadalupe Villarreal; Dong-Jin Oh; Douglas J Rhee

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3542. doi:

ARVO Annual Meeting Abstract June 2015

The outflow facility of SPARC KO and WT mice

Dong-Jin Oh; Ling Yu; Min Hyung Kang; Douglas J Rhee

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2003. doi:

ARVO Annual Meeting Abstract June 2015

Vision Loss and Recovery after Baerveldt Glaucoma Implant Surgery

Esther Lee Kim; Marc Toeteberg-Harms; Jeffrey S Tran; Jasdeep S Chahal; Douglas J Rhee; Vikas Chopra; Rohit Varma; Brian A Francis

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2710. doi:

ARVO Annual Meeting Abstract June 2015

The Chaperone Activity of SPARC for ECM Proteins in the Presence of MMP-2 and MMP-9

Kurt Scavelli; Ayan Chatterjee; Min Hyung Kang; Douglas J Rhee

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3261. doi:

ARVO Annual Meeting Abstract June 2015

Overexpression of thrombospondin-1 (TSP1) in Human Trabecular Meshwork Alters Extracellular Matrix

Min Hyung Kang; Dong-Jin Oh; Douglas J Rhee

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3281. doi:

Glaucoma November 2014

Canonical Wnt Signaling Regulates Extracellular Matrix Expression in the Trabecular Meshwork

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Guadalupe Villarreal, Jr; Ayan Chatterjee; Sarah S. Oh; Dong-Jin Oh; Min Hyung Kang; Douglas J. Rhee
TAGS: extracellular matrix, lithium chloride, proteins, signal transduction, trabecular meshwork, dominant-negative mutation, family, intraocular pressure, micrornas, immunoblotting
Invest. Ophthalmol. Vis. Sci.. 2014; 55(11):7433-7440. doi: https://doi.org/10.1167/iovs.13-12652

Includes: Supplemental Content

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Regulation and role of clusterin, a secretory chaperone protein, on intraocular pressure

Collagen binding site in SPARC is required for chaperone activity

TGFβ2-Hepcidin Feed-Forward Loop in the Trabecular Meshwork Implicates Iron in Glaucomatous Pathology

Clusterin-Cathepsin K Signaling in Trabecular Meshwork Outflow Pathway Regulates Intraocular Pressure

Glycosylation of SPARC is Critical for Binding to Extracellular Matrix Proteins and Protection from Matrix Metalloproteinase Degradation

Adenoviral Gene Transfer of TGF-β2 Upregulates Intraocular Pressure through SPARC and Integrin-Linked Kinase in Mice

Suppression of SPARC in human trabecular meshwork cells upregulates Plasminogen Activator Inhibitor-1

Variability of tensile strength during microsurgical knot construction: A comparative study of polyglactin 910 and lactomer suture

TGF-β2 upregulates the extracellular proteins through SPARC and Integrin-Linked Kinase in Human Trabecular Meshwork

Testosterone Pathway Genetic Polymorphisms in Relation to Primary Open-Angle Glaucoma: An Analysis in Two Large Datasets

Suppression of Parvin-a in Human Trabecular Meshwork Downregulates Extracellular Matrix Components

Aging changes in aqueous humor dynamics and ocular biometrics of SPARC null mice

Suppression of Integrin-Linked Kinase in Human Trabecular Meshwork Alters SPARC’s Effect on Extracellular Matrix and Intraocular Pressure

Suppression of thrombospondin-1 (TSP1) in Human Trabecular Meshwork Alters Extracellular Matrix

Treatment with AICAR decreases intraocular pressure in perfused ex vivo human anterior segments

The outflow facility of SPARC KO and WT mice

Vision Loss and Recovery after Baerveldt Glaucoma Implant Surgery

The Chaperone Activity of SPARC for ECM Proteins in the Presence of MMP-2 and MMP-9

Overexpression of thrombospondin-1 (TSP1) in Human Trabecular Meshwork Alters Extracellular Matrix

Canonical Wnt Signaling Regulates Extracellular Matrix Expression in the Trabecular Meshwork

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