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ARVO Annual Meeting Abstract June 2025

Quantitative Proteomics Analysis of MELAS iPSC-derived RPE Cells with Mitochondrial Heteroplasmy.

Sujoy Bhattacharya; Kristie Lindsey Rose; Purvi Patel; Weihong Huo; Edward Chaum

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1314.

ARVO Annual Meeting Abstract June 2024

Transcriptomic Analysis of Prominin-1-knockout Mouse RPE by RNA-sequencing

Sujoy Bhattacharya; Sharon Yang; Bretton P. Nabit; Jinggang Yin; Edward Chaum

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6451a.

Retina November 2023

A Microfluidic Platform for the Time-Resolved Interrogation of Polarized Retinal Pigment Epithelial Cells

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Eric C. Spivey; Jinggang Yin; Edward Chaum; John P. Wikswo
TAGS: retinal pigment cell, vascular endothelial growth factor a, fluid flow, bodily secretions, hypoxia
Trans. Vis. Sci. Tech.. 2023; 12(11):28. https://doi.org/10.1167/tvst.12.11.28

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

A Novel Microfluidic “Puck” Assembly for Investigating Polarized Apical and Basal Secretions by Phenotypically Characterized Retinal Pigment Epithelial Cells

Edward Chaum; Jinggang Yin; Eric c Spivey; John Wixwo

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2976.

ARVO Annual Meeting Abstract June 2023

Loss of Prom1 Impairs Autophagy via mTORC1-TFEB signaling and Promotes RPE Degeneration in a Mouse Model

Sujoy Bhattacharya; Jinggang Yin; Weihong Huo; Tonia S Rex; Edward Chaum

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3888.

ARVO Annual Meeting Abstract June 2022

Modeling of mitochondrial bioenergetics and autophagy impairment in MELAS-mutant iPSC-derived retinal pigment epithelial cells

Sujoy Bhattacharya; Jinggang Yin; Weihong Huo; Edward Chaum

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):800 – F0359.

ARVO Annual Meeting Abstract June 2020

Molecular Cross-Talk between Prominin-1 and STAT3 Signaling Controls Autophagy in Human Retinal Pigment Epithelial and Glioblastoma Cells

Sujoy Bhattacharya; Jinggang Yin; Lawrence M. Pfeffer; Edward Chaum

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1513.

ARVO Annual Meeting Abstract July 2019

Clinical Validation of a Deep Learning Automated Algorithm for the Detection of Diabetic Retinopathy and Macular Edema

Kristen Stebbins; Ynjiun Wang; Lilian Tang; Naren Suri; Su Wang; Amish Purohit; Max Johnson; Edward Chaum

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1440.

ARVO Annual Meeting Abstract July 2019

“Plexitome”, a Novel, Microfabricated Device for the Treatment of Corneal Abrasions and Recurrent Corneal Erosions

Edward Chaum; Christina Winborn

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3210.

ARVO Annual Meeting Abstract July 2018

Prominin-1 interacts with vascular endothelial growth factor and regulates its secretion in human retinal pigment epithelial cells

Sujoy Bhattacharya; Jinggang Yin; Weihong Huo; Edward Chaum

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3999.

ARVO Annual Meeting Abstract July 2018

Real-time Monitoring of Mitochondria Depletion and Rescue by Platelet Fusion Cybrids in the RPE using FlowSight Cytometry and Confocal Microscopy

Edward Chaum; Weihong Huo; Jinggang Yin

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4038.

ARVO Annual Meeting Abstract July 2018

Inhibition of Experimental PVR by a Novel Nutlin-3 Analogue

Jinggang Yin; Weihong Huo; Kip Guy; Edward Chaum

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5322.

ARVO Annual Meeting Abstract July 2018

Patient Follow Up After Teleretinal Imaging in a Primary Care Network

Kristen Stebbins; Edward Chaum

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5241.

ARVO Annual Meeting Abstract June 2017

Prom1-dependent Autophagy Prevents Mitochondrial Damage and Apoptosis in Human Retinal Pigment Epithelial Cells

Sujoy Bhattacharya; Jinggang Yin; Weihong Huo; Edward Chaum

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):618.

Biochemistry and Molecular Biology April 2017

Prominin-1 Is a Novel Regulator of Autophagy in the Human Retinal Pigment Epithelium

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Sujoy Bhattacharya; Jinggang Yin; Christina S. Winborn; Qiuhua Zhang; Junming Yue; Edward Chaum
TAGS: autophagy, mtor serine-threonine kinases, signal transduction, ac133 antigen, retinal pigment cell, autophagosomes
Invest. Ophthalmol. Vis. Sci.. 2017; 58(4):2366-2387. https://doi.org/10.1167/iovs.16-21162

Includes: Supplemental Content

ARVO Annual Meeting Abstract September 2016

Modulation of Epithelial Mesenchymal Transition (EMT) Through the Notch Signaling Pathway in Human Retinal Pigment Epithelial Cells

Jinggang Yin; Junming Yue; Gunnan zhao; Wenying Huo; Weihong Huo; Edward Chaum

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):264.

ARVO Annual Meeting Abstract September 2016

Prominin 1 Plays a Central Role in Regulating Stress-induced Autophagy in the Retinal Pigment Epithelium

Edward Chaum; Christina S Winborn; Sujoy Bhattacharya; Jinggang Yin

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6041.

ARVO Annual Meeting Abstract September 2016

Molecular Mechanisms Regulating Prom1-dependent Autophagy in Human Retinal Pigment Epithelial Cells

Sujoy Bhattacharya; Qiuhua Zhang; Jinggang Yin; Christina S Winborn; Edward Chaum

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6042.

ARVO Annual Meeting Abstract June 2015

Transcriptional factor KLF4 inhibits epithelial to mesenchymal transition by attenuating TGFβ pathway in human retinal pigment epithelial cells

Lu Lu; Qingqing Gu; yinan wang; Jinggang Yin; yanan zou; Edward Chaum; Junming Yue

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4238.

ARVO Annual Meeting Abstract June 2015

Prom1 is a Novel Regulator of Autophagy in the Human Retinal Pigment Epithelium

Sujoy Bhattacharya; Jinggang Yin; Christina Winborn; Edward Chaum; Retinal Cell Biology

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2395.

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Quantitative Proteomics Analysis of MELAS iPSC-derived RPE Cells with Mitochondrial Heteroplasmy.

Transcriptomic Analysis of Prominin-1-knockout Mouse RPE by RNA-sequencing

A Microfluidic Platform for the Time-Resolved Interrogation of Polarized Retinal Pigment Epithelial Cells

A Novel Microfluidic “Puck” Assembly for Investigating Polarized Apical and Basal Secretions by Phenotypically Characterized Retinal Pigment Epithelial Cells

Loss of Prom1 Impairs Autophagy via mTORC1-TFEB signaling and Promotes RPE Degeneration in a Mouse Model

Modeling of mitochondrial bioenergetics and autophagy impairment in MELAS-mutant iPSC-derived retinal pigment epithelial cells

Molecular Cross-Talk between Prominin-1 and STAT3 Signaling Controls Autophagy in Human Retinal Pigment Epithelial and Glioblastoma Cells

Clinical Validation of a Deep Learning Automated Algorithm for the Detection of Diabetic Retinopathy and Macular Edema

“Plexitome”, a Novel, Microfabricated Device for the Treatment of Corneal Abrasions and Recurrent Corneal Erosions

Prominin-1 interacts with vascular endothelial growth factor and regulates its secretion in human retinal pigment epithelial cells

Real-time Monitoring of Mitochondria Depletion and Rescue by Platelet Fusion Cybrids in the RPE using FlowSight Cytometry and Confocal Microscopy

Inhibition of Experimental PVR by a Novel Nutlin-3 Analogue

Patient Follow Up After Teleretinal Imaging in a Primary Care Network

Prom1-dependent Autophagy Prevents Mitochondrial Damage and Apoptosis in Human Retinal Pigment Epithelial Cells

Prominin-1 Is a Novel Regulator of Autophagy in the Human Retinal Pigment Epithelium

Modulation of Epithelial Mesenchymal Transition (EMT) Through the Notch Signaling Pathway in Human Retinal Pigment Epithelial Cells

Prominin 1 Plays a Central Role in Regulating Stress-induced Autophagy in the Retinal Pigment Epithelium

Molecular Mechanisms Regulating Prom1-dependent Autophagy in Human Retinal Pigment Epithelial Cells

Transcriptional factor KLF4 inhibits epithelial to mesenchymal transition by attenuating TGFβ pathway in human retinal pigment epithelial cells

Prom1 is a Novel Regulator of Autophagy in the Human Retinal Pigment Epithelium

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