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Retinal Cell Biology December 2024

Elevation of Granulocyte Colony Stimulating Factor in Human AMD Donor RPE-Choroid

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Kelly Mulfaul; Adnan H. Khan; Samantha G. Schwarte; Andrew P. Voigt; Rachel F. Moore; Lawrence A. Potempa; Kai Wang; Todd E. Scheetz; Edwin M. Stone; Budd A. Tucker; Robert F. Mullins
TAGS: choroid, donors, granulocyte colony-stimulating factor, proteins, recombinant granulocyte colony stimulating factor, body tissue
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):15. https://doi.org/10.1167/iovs.65.14.15

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Device-free isolation of photoreceptors from patient stem cell derived retinal organoids

Nicholas Edwin Stone; Laura R Bohrer; Nathaniel Kevin Mullin; Robert F Mullins; Edwin M Stone; Budd A. Tucker

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):950.

ARVO Annual Meeting Abstract June 2024

Characterization and gene-based treatment of a novel CRISPR-Cas9 generated Mak -deficient rat model of photoreceptor degeneration

Lorena Haefeli; Luke A Wiley; Cathryn Cranston; Heather Daggett; Ian Han; Edwin M Stone; Robert F Mullins; Budd A. Tucker

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2216.

ARVO Annual Meeting Abstract June 2024

Complement injury and CRP stress alter inflammatory cytokine secretion in AMD iPSC derived choroidal endothelial cells.

Kelly Mulfaul; Samantha G Schwarte; Megan J Riker; Brynnon E Harman; Edwin M Stone; Budd A. Tucker; Robert F Mullins

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):736.

ARVO Annual Meeting Abstract June 2024

iPSC derived choroidal endothelial cell delivery using laminin-based hydrogels for the treatment of AMD

Narendra Pandala; Ian Han; Emily Meyering; Edwin M Stone; Robert F Mullins; Budd A. Tucker

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1542.

ARVO Annual Meeting Abstract June 2024

Development of chemically induced choroidal injury models for the study and treatment of AMD.

Ian Han; Narendra Pandala; Lorena Haefeli; Mallory J Lang; Edwin M Stone; Robert F Mullins; Budd A. Tucker

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5382.

ARVO Annual Meeting Abstract June 2024

Transplantation of cGMP compliant iPSC-derived retinal progenitor cells

Laura R Bohrer; Luke A Wiley; Allison T Wright; Louisa Affatigato; Robert F Mullins; Edwin M Stone; Ian Han; Budd A. Tucker

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1541.

ARVO Annual Meeting Abstract June 2024

miR-181 expression and inhibition: a potential new treatment for dominant rhodopsin associated retinitis pigmentosa.

Renato Jensen; Lorena Haefeli; Luke A Wiley; Colleen Stein; Jessica L Fick; Malia Collins; Robert F Mullins; Ian Han; Edwin M Stone; Ryan Boudreau; Budd A. Tucker

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2215.

ARVO Annual Meeting Abstract June 2024

Retinal differentiation propensity is linked to pluripotency factor localization and donor cell epigenetic memory.

Jessica A Cooke; Nathaniel Kevin Mullin; Douglas B Critser; Edwin M Stone; Robert F Mullins; Budd A. Tucker

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1543.

ARVO Annual Meeting Abstract June 2024

A computational model of retinal atrophy and visual acuity: applications to macular degeneration

S Scott Whitmore; Douglas B Critser; Edwin M Stone; Ian Han

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4454.

ARVO Annual Meeting Abstract June 2024

A dual AAV vector approach for the treatment of ABCA4 -associated retinal disease.

Erin R Burnight; Luke A Wiley; Dalyz Ochoa; Katayoun Varzavand; Seongjin Seo; Ian Han; Robert F Mullins; Edwin M Stone; Budd A. Tucker

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1540.

ARVO Annual Meeting Abstract June 2024

Inflammatory phenotype associated with high risk MMP9 genotype in neovascular AMD

Elliott H Sohn; Zeb Zacharias; kyungmoo lee; Chirantan Mukhopadhyay; Razek Coussa; Ian Han; Todd E Scheetz; John H Fingert; Edwin M Stone; jon houtman; Milan Sonka

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3791.

ARVO Annual Meeting Abstract June 2024

The role of nicotinamide N-methyltransferase in choroidal endothelial cells: possible role in macular neovascularization

Emma Mae Navratil; Miles J Flamme-Wiese; Adnan Khan; Xiuying Liu; Luke A Wiley; Edwin M Stone; Budd A. Tucker; Robert F Mullins

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4969.

ARVO Annual Meeting Abstract June 2024

The NR2E3 variant c.932G>A (p.Arg311Gln) creates an alternative splice acceptor leading to an in-frame deletion of 186 nucleotides

Nathaniel Kevin Mullin; Laura R Bohrer; Kristin R Anfinson; Jeaneen L Andorf; Robert F Mullins; Budd A. Tucker; Edwin M Stone

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4514.

ARVO Annual Meeting Abstract June 2024

METTL23 mutations and normal tension glaucoma (NTG) in a United States population

John H Fingert; Mallory R. Tollefson; Benjamin R. Roos; Erin Boese; Andrew E Pouw; Edwin M Stone; Michael Schnieders; Todd E Scheetz

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4235.

ARVO Annual Meeting Abstract June 2024

Developing a molecular assay to predict hemangioblastoma phenotype severity in VHL disease

Lola Lozano; Edwin M Stone; Robert F Mullins; Budd A. Tucker; Elaine Binkley

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6033.

Retinal Cell Biology October 2023

Gene Expression Within a Human Choroidal Neovascular Membrane Using Spatial Transcriptomics

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Andrew P. Voigt; Nathaniel K. Mullin; Emma M. Navratil; Miles J. Flamme-Wiese; Li-Chun Lin; Todd E. Scheetz; Ian C. Han; Edwin M. Stone; Budd A. Tucker; Robert F. Mullins
TAGS: choroidal neovascularization, gene expression, macular neovascularization, genes, sequence analysis, rna, donors, choroid, eye
Invest. Ophthalmol. Vis. Sci.. 2023; 64(13):40. https://doi.org/10.1167/iovs.64.13.40

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

NR2E3-deficient progenitors commit to a rod fate yet fail to form mature rod photoreceptors in an induced pluripotent stem cell-based model of human retinal development

Nathaniel Kevin Mullin; Laura R Bohrer; Allison Wright; Kristin Anfinson; Andrew P Voigt; Edwin M Stone; Robert Mullins; Budd A. Tucker

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1893.

ARVO Annual Meeting Abstract June 2023

Inflammatory cytokine profiling identifies elevated G-CSF protein in human age-related macular degeneration (AMD) donor choroid.

Kelly Mulfaul; Xiuying Liu; Megan J Riker; Edwin M Stone; Budd A. Tucker; Robert Mullins

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5388.

ARVO Annual Meeting Abstract June 2023

Engineering a photoreceptor cell-RPE microphysiological system

Laura R Bohrer; Arwin Shrestha; Erin R Burnight; Luan M. Streb; Robert Mullins; Edwin M Stone; Budd A. Tucker

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3177.

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Elevation of Granulocyte Colony Stimulating Factor in Human AMD Donor RPE-Choroid

Device-free isolation of photoreceptors from patient stem cell derived retinal organoids

Characterization and gene-based treatment of a novel CRISPR-Cas9 generated Mak -deficient rat model of photoreceptor degeneration

Complement injury and CRP stress alter inflammatory cytokine secretion in AMD iPSC derived choroidal endothelial cells.

iPSC derived choroidal endothelial cell delivery using laminin-based hydrogels for the treatment of AMD

Development of chemically induced choroidal injury models for the study and treatment of AMD.

Transplantation of cGMP compliant iPSC-derived retinal progenitor cells

miR-181 expression and inhibition: a potential new treatment for dominant rhodopsin associated retinitis pigmentosa.

Retinal differentiation propensity is linked to pluripotency factor localization and donor cell epigenetic memory.

A computational model of retinal atrophy and visual acuity: applications to macular degeneration

A dual AAV vector approach for the treatment of ABCA4 -associated retinal disease.

Inflammatory phenotype associated with high risk MMP9 genotype in neovascular AMD

The role of nicotinamide N-methyltransferase in choroidal endothelial cells: possible role in macular neovascularization

The NR2E3 variant c.932G>A (p.Arg311Gln) creates an alternative splice acceptor leading to an in-frame deletion of 186 nucleotides

METTL23 mutations and normal tension glaucoma (NTG) in a United States population

Developing a molecular assay to predict hemangioblastoma phenotype severity in VHL disease

Gene Expression Within a Human Choroidal Neovascular Membrane Using Spatial Transcriptomics

NR2E3-deficient progenitors commit to a rod fate yet fail to form mature rod photoreceptors in an induced pluripotent stem cell-based model of human retinal development

Inflammatory cytokine profiling identifies elevated G-CSF protein in human age-related macular degeneration (AMD) donor choroid.

Engineering a photoreceptor cell-RPE microphysiological system

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