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ARVO Annual Meeting Abstract June 2017

Interferon beta modulates immune-mediated retinal inflammation by impairing T-cell trafficking

Jun Chen; Weiwei Wang; Zilin Chen; Hongyan Zhou; Eric F Wawrousek; Igal Gery; Rachel R Caspi

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):547.

ARVO Annual Meeting Abstract June 2017

Cryba1 : Do its two gene products (βA3- and βA1-crystallin) have distinct functions?

J Samuel Zigler; Eric F Wawrousek; Lixia Lu; Guo-Tong Xu; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5307.

ARVO Annual Meeting Abstract April 2014

βA3/A1-crystallin is a local mediator in astrocytes, regulating the Notch/STAT3 signaling axis

Mallika Valapala; Jian Fei Hu; J Samuel Zigler; Stacey L Hose; Eric F Wawrousek; Jiang Qian; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2275.

ARVO Annual Meeting Abstract June 2013

βA3/A1-crystallin is essential for lysosome-mediated waste clearance in retinal pigmented epithelial (RPE) cells

Mallika Valapala; Christine Wilson; Imran Bhutto; Stacey Hose; Seth Greenbaum; Rhonda Grebe; James Handa; Lijin Dong; Eric Wawrousek; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):1786.

ARVO Annual Meeting Abstract June 2013

Loss of βA3/A1-crystallin alters normal remodeling of the hyaloid vasculature

Debasish Sinha; Mallika Valapala; J Zigler; Gerard Lutty; Eric Wawrousek; Lijin Dong; Stacey Hose

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):3194.

ARVO Annual Meeting Abstract June 2013

Deletion and mutation of βA3/A1-crystallin produce distinct ocular phenotypes

J Zigler; Lijin Dong; Eric Wawrousek; Stacey Hose; Limin Gu; Guo-Tong Xu; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):3685.

Immunology and Microbiology May 2012

The Rd8 Mutation of the Crb1 Gene Is Present in Vendor Lines of C57BL/6N Mice and Embryonic Stem Cells, and Confounds Ocular Induced Mutant Phenotypes

PDF

Mary J. Mattapallil; Eric F. Wawrousek; Chi-Chao Chan; Hui Zhao; Jayeeta Roychoudhury; Thomas A. Ferguson; Rachel R. Caspi
TAGS: embryonic stem cells, genes, mice, mice, inbred c57bl, mutation, phenotype
Invest. Ophthalmol. Vis. Sci.. 2012; 53(6):2921-2927. https://doi.org/10.1167/iovs.12-9662

ARVO Annual Meeting Abstract March 2012

Disruption Of The Ubiquitin-proteasome Pathway In The Lens Alters Lens Proteome

Elizabeth A. Whitcomb; Fu Shang; Phillip Wilmarth; Ke Liu; Larry L. David; Maria A. Caceres; Eric F. Wawrousek; Allen Taylor

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):1045.

ARVO Annual Meeting Abstract March 2012

Cell-cell Interaction with APC, not IL-23, is Required for Naive CD4 Cells to Acquire Pathogenicity During Th17 Lineage Commitment

Guangpu Shi; Jenna D. Lovaas; Cuiyan Tan; Barbara P. Vistica; Eric F. Wawrousek; Mehak K. Aziz; Rachael C. Rigden; Rachel R. Caspi; Igal Gery

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):5487.

Lens July 2011

Overexpression of Human γC-crystallin 5 bp Duplication Disrupts Lens Morphology in Transgenic Mice

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Zhiwei Ma; Wenliang Yao; Veena Theendakara; Chi-Chao Chan; Eric Wawrousek; J. Fielding Hejtmancik
TAGS: crystallins, language morphology, lens (device), lens, crystalline, mice, transgenic, morphology, protein overexpression, mice, polymerase chain reaction, cataract
Invest. Ophthalmol. Vis. Sci.. 2011; 52(8):5369-5375. https://doi.org/10.1167/iovs.11-7168

ARVO Annual Meeting Abstract April 2011

Acquisition of Th1, Th17, or Treg Phenotypes Differs Among CD4 T Cells in Ocular Inflammation Triggered by Different TLR Ligands

Guangpu Shi; Barbara P. Vistica; Lindsey F. Nugent; Eric F. Wawrousek; Igal Gery

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):2279.

ARVO Annual Meeting Abstract April 2011

Defects in Optic Nerve Glia and in the Lens During Embryonic Development May Cause Persistent Fetal Vasculature (PFV) Disease

Stacey L. Hose; Laura Asnaghi; Cheng Zhang; Marisol Cano; Morton F. Goldberg; Charles G. Eberhart; Eric F. Wawrousek; J. S. Zigler, Jr.; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):2356.

Retina March 2008

Elevated Retina-Specific Expression of the Small Heat Shock Protein, αA-crystallin, Is Associated with Photoreceptor Protection in Experimental Uveitis

PDF

Narsing A. Rao; Sindhu Saraswathy; Guey Shuang Wu; George S. Katselis; Eric F. Wawrousek; Suraj Bhat
TAGS: crystallins, retina
Invest. Ophthalmol. Vis. Sci.. 2008; 49(3):1161-1171. https://doi.org/10.1167/iovs.07-1259

Lens November 2006

Inbred FVB/N Mice Are Mutant at the cp49/Bfsp2 Locus and Lack Beaded Filament Proteins in the Lens

PDF

Vladimir N. Simirskii; Robert S. Lee; Eric F. Wawrousek; Melinda K. Duncan
TAGS: lens (device), lens, crystalline, mice, proteins, mutation
Invest. Ophthalmol. Vis. Sci.. 2006; 47(11):4931-4934. https://doi.org/10.1167/iovs.06-0423

Retina September 2004

RS-1 Gene Delivery to an Adult Rs1h Knockout Mouse Model Restores ERG b-Wave with Reversal of the Electronegative Waveform of X-Linked Retinoschisis

PDF

Yong Zeng; Yuichiro Takada; Sten Kjellstrom; Kelaginamane Hiriyanna; Atsuhiro Tanikawa; Eric Wawrousek; Nizar Smaoui; Rafael Caruso; Ronald A. Bush; Paul A. Sieving
TAGS: adult, electroretinography, erg protein, human, genes, mice, proteins, spatial vectors, waveforms, x-linked retinoschisis, disease vectors
Invest. Ophthalmol. Vis. Sci.. 2004; 45(9):3279-3285. https://doi.org/10.1167/iovs.04-0576

Immunology and Microbiology March 2004

Central Immunotolerance in Transgenic Mice Expressing a Foreign Antigen under Control of the Rhodopsin Promoter

PDF

Don-Il Ham; Stephen J. Kim; Jun Chen; Barbara P. Vistica; Robert N. Fariss; Robert S. Lee; Eric F. Wawrousek; Hiroshi Takase; Cheng-Rong Yu; Charles E. Egwuagu; Chi-Chao Chan; Igal Gery
TAGS: antigens, mice, rhodopsin
Invest. Ophthalmol. Vis. Sci.. 2004; 45(3):857-862. https://doi.org/10.1167/iovs.03-1028

Lens June 2002

Cataract- and Lens-Specific Upregulation of ARK Receptor Tyrosine Kinase in Emory Mouse Cataract

PDF

Nancy L. Sheets; Bharesh K. Chauhan; Eric Wawrousek; J. Fielding Hejtmancik; Ales Cvekl; Marc Kantorow
TAGS: cataract, crystallins, lens (device), lens, crystalline, mice, receptor protein-tyrosine kinases, up-regulation (physiology)
Invest. Ophthalmol. Vis. Sci.. 2002; 43(6):1870-1875.

Immunology and Microbiology March 2002

Induction of Ocular Inflammation by T-Helper Lymphocytes Type 2

PDF

Stephen J. Kim; Meifen Zhang; Barbara P. Vistica; Chi-Chao Chan; De-Fen Shen; Eric F. Wawrousek; Igal Gery
TAGS: cytokine, eye, eye inflammation, helper-inducer t-lymphocytes, inflammation, lymphocytes, mice, th2 cells, th1 cells
Invest. Ophthalmol. Vis. Sci.. 2002; 43(3):758-765.

Lens November 2001

αB-Crystallin in Lens Development and Muscle Integrity: A Gene Knockout Approach

PDF

James P. Brady; Donita L. Garland; D. Earl Green; Ernst R. Tamm; Frank J. Giblin; Eric F. Wawrousek
TAGS: crystallins, lens (device), lens, crystalline, mice, mice, knockout, muscle, personal integrity, genes, vif, proteins
Invest. Ophthalmol. Vis. Sci.. 2001; 42(12):2924-2934.

Lens February 2001

Regulation of GSH in αA-Expressing Human Lens Epithelial Cell Lines and in αA Knockout Mouse Lenses

PDF

Ram Kannan; Bin Ouyang; Eric Wawrousek; Neil Kaplowitz; Usha P. Andley
TAGS: epithelial cells, glasgow coma scale, lens (device), lens, crystalline, mice, knockout, proteins, regulation, mice, western blotting
Invest. Ophthalmol. Vis. Sci.. 2001; 42(2):409-416.

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Interferon beta modulates immune-mediated retinal inflammation by impairing T-cell trafficking

Cryba1 : Do its two gene products (βA3- and βA1-crystallin) have distinct functions?

βA3/A1-crystallin is a local mediator in astrocytes, regulating the Notch/STAT3 signaling axis

βA3/A1-crystallin is essential for lysosome-mediated waste clearance in retinal pigmented epithelial (RPE) cells

Loss of βA3/A1-crystallin alters normal remodeling of the hyaloid vasculature

Deletion and mutation of βA3/A1-crystallin produce distinct ocular phenotypes

The Rd8 Mutation of the Crb1 Gene Is Present in Vendor Lines of C57BL/6N Mice and Embryonic Stem Cells, and Confounds Ocular Induced Mutant Phenotypes

Disruption Of The Ubiquitin-proteasome Pathway In The Lens Alters Lens Proteome

Cell-cell Interaction with APC, not IL-23, is Required for Naive CD4 Cells to Acquire Pathogenicity During Th17 Lineage Commitment

Overexpression of Human γC-crystallin 5 bp Duplication Disrupts Lens Morphology in Transgenic Mice

Acquisition of Th1, Th17, or Treg Phenotypes Differs Among CD4 T Cells in Ocular Inflammation Triggered by Different TLR Ligands

Defects in Optic Nerve Glia and in the Lens During Embryonic Development May Cause Persistent Fetal Vasculature (PFV) Disease

Elevated Retina-Specific Expression of the Small Heat Shock Protein, αA-crystallin, Is Associated with Photoreceptor Protection in Experimental Uveitis

Inbred FVB/N Mice Are Mutant at the cp49/Bfsp2 Locus and Lack Beaded Filament Proteins in the Lens

RS-1 Gene Delivery to an Adult Rs1h Knockout Mouse Model Restores ERG b-Wave with Reversal of the Electronegative Waveform of X-Linked Retinoschisis

Central Immunotolerance in Transgenic Mice Expressing a Foreign Antigen under Control of the Rhodopsin Promoter

Cataract- and Lens-Specific Upregulation of ARK Receptor Tyrosine Kinase in Emory Mouse Cataract

Induction of Ocular Inflammation by T-Helper Lymphocytes Type 2

αB-Crystallin in Lens Development and Muscle Integrity: A Gene Knockout Approach

Regulation of GSH in αA-Expressing Human Lens Epithelial Cell Lines and in αA Knockout Mouse Lenses

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