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ARVO Annual Meeting Abstract June 2020

Development of 3D retinal grafts for the treatment of retinal degenerative blindness

Laura R Bohrer; Ian C Han; Jessica A Cooke; Erin R Burnight; Arwin Shrestha; Louisa Affatigato; Luke A Wiley; Kristan Worthington; Katherine N Gibson-corley; Robert F Mullins; Edwin M Stone; Budd Tucker

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2511. doi:

ARVO Annual Meeting Abstract July 2019

Generation of rod- vs. cone-dominant patient-derived 3D retinal grafts for the treatment of retinal degenerative blindness

Laura R. Bohrer; Jessica A. Cooke; Arwin Shrestha; Erin R. Burnight; Kristin R. Anfinson; Malia M. Collins; Robert F Mullins; Edwin M Stone; Kristan S. Worthington; Luke A. Wiley; Budd Tucker

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2871. doi:

ARVO Annual Meeting Abstract July 2019

Development of a CRISPR dCas9-KRAB based strategy for treatment for dominant retinal degenerative blindness

Erin R. Burnight; Jessica A. Cooke; Darcey Klaahsen; Luan M. Streb; Louisa M. Affatigato; Robert F Mullins; Edwin M Stone; Budd Tucker

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5983. doi:

ARVO Annual Meeting Abstract July 2018

Assessment of transduction efficiency and tropism of different adeno-associated virus (AAV) serotypes based on route of delivery in rats

Ian C Han; Chunhua Jiao; Emily E Kaalberg; Sajag Bhattarai; Erin R Burnight; Budd A Tucker; Robert F Mullins; Edwin M Stone

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5657. doi:

ARVO Annual Meeting Abstract June 2017

Using pathway-specific reporter and direct conversion constructs to investigate Juvenile Neuronal Ceroid Lipofuscinosis.

Lorenzo L Lones; Erin R Burnight; Dalyz Ochoa; Joseph C Giacalone; Robert A Madumba; Robert F Mullins; Edwin M Stone; Budd Tucker; Luke A Wiley

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):263. doi:

ARVO Annual Meeting Abstract June 2017

Development of corneal endothelial cell-specific reporter constructs and a CRISPR-Cas9 genome editing approach to study Fuchs Dystrophy.

Luke A Wiley; Laura R Bohrer; Erin R Burnight; Elizabeth L Kennedy; Edwin M Stone; Mark A Greiner; Michael D Wagoner; Budd Tucker

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1444. doi:

ARVO Annual Meeting Abstract June 2017

Characterization and Treatment of RPGR-associated Photoreceptor Disease

Joseph C Giacalone; Luke A Wiley; Erin R Burnight; Jeaneen Andorf; Luan M Streb; Louisa M Affatigato; Cathryn Cranston; Dalyz Ochoa; Robert F Mullins; Budd Tucker; Edwin M Stone

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4515. doi:

ARVO Annual Meeting Abstract June 2017

Transduction of photoreceptors following subretinal injections of AAV5 and helper-dependent adenovirus in human retina ex vivo and pig retina in vivo

Brittni Scruggs; Erin R Burnight; Chunhua Jiao; Luke A Wiley; Robert F Mullins; Edwin M Stone; Budd Tucker; Elliott Sohn

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4534. doi:

ARVO Annual Meeting Abstract June 2017

Combining CRISPR based genome editing and patient specific iPSCs to elucidate the pathophysiologic role of WFS1 mutations in optic atrophy.

Tasneem Putliwala Sharma; Joseph C Giacalone; Erin R Burnight; Kristin R. Anfinson; Jill S. Wiley; John Fingert; Robert F Mullins; Edwin M Stone; Budd Tucker

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5585. doi:

ARVO Annual Meeting Abstract September 2016

Assessing transcriptional diversity of human and mouse photoreceptor cells by single-cell RNA-Seq

S Scott Whitmore; Adam P DeLuca; Luke A Wiley; Erin R Burnight; Miles J Flamme-Wiese; Budd A Tucker; Robert F Mullins; Todd E Scheetz; Edwin M Stone

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4795. doi:

ARVO Annual Meeting Abstract September 2016

HUMAN DISEASE MODELING OF TRNT1 -ASSOCIATED RETINITIS PIGMENTOSA IN PATIENT-DERIVED CELLS

Tasneem P Sharma; Joseph C Giacalone; Erin R Burnight; Luke A Wiley; Jill S Wiley; Robert A Madumba; Robert F Mullins; Edwin M Stone; Budd A Tucker

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6060. doi:

ARVO Annual Meeting Abstract September 2016

Production of clinical-grade patient-specific iPSCs and transplantable photoreceptor precursor cells for the treatment of retinal degenerative blindness.

Budd A Tucker; Luke A Wiley; Erin R Burnight; Kristan S Worthington; Cathryn M Cranston; Kristin R Anfinson; Robert F Mullins; Edwin M Stone

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6064. doi:

ARVO Annual Meeting Abstract September 2016

Modeling Enhanced S-cone Syndrome Using Patient-Specific iPSC-derived Retinal Eyecups

Luke A Wiley; Erin R Burnight; Jennifer A Halder; Jessica A Penticoff; Christine M Haas; Robert F Mullins; Edwin M Stone; Budd A Tucker

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

ARVO Annual Meeting Abstract September 2016

Development of a step-wise protocol for the generation of human induced pluripotent stem cell-derived choroidal endothelial cells.

Allison E Songstad; Luke A Wiley; Erin R Burnight; S Scott Whitmore; Emily E Kaalberg; Megan J Riker; Edwin M Stone; Robert F Mullins; Budd A Tucker

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1136. doi:

ARVO Annual Meeting Abstract September 2016

CRISPR/Cas9-mediated genome editing for correction of inherited retinal disease mutations.

Erin R Burnight; Luke A Wiley; Adam P DeLuca; Douglas J. Oppedal; Todd E Scheetz; Robert F Mullins; Edwin M Stone; Budd A Tucker

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1157. doi:

ARVO Annual Meeting Abstract September 2016

CRISPR-based Genome Editing for treatment of CEP290 -IVS26-associated Leber Congenital Amaurosis (LCA)

Edwin M Stone; Erin R Burnight; Luke A Wiley; Luan M Streb; Louisa M Affatigato; Jeaneen A Andorf; Robert F Mullins; Budd A Tucker

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

ARVO Annual Meeting Abstract September 2016

Patient-specific iPSCs to investigate pathophysiology and develop treatments for RPGR -associated XLRP

Joseph C Giacalone; Erin R Burnight; Tasneem P Sharma; Luke A Wiley; Dalyz Ochoa; Malia Collins; Robert F Mullins; Budd A Tucker; Edwin M Stone

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

ARVO Annual Meeting Abstract June 2015

Using RNA-mediated Genome Editing to Create an Animal Model of Retinal Dystrophy for Analysis of in vivo CRISPR/CAS9 Treatment Efficacy.

Erin R Burnight; Patrick D. Hsu; Dalyz Ochoa; Jill S. Wiley; Jennifer S. Halder; Feng Zhang; Robert F Mullins; Edwin M Stone; Budd Tucker

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3589. doi:

ARVO Annual Meeting Abstract June 2015

RPGR ORF15: From Clinical Sequencing to Treatment

Joseph Giacalone; Luke A Wiley; Luan A. Streb; Heather T. Daggett; Erin R Burnight; Robert F Mullins; Budd Tucker; Edwin M Stone

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3597. doi:

ARVO Annual Meeting Abstract April 2014

CEP290 gene addition rescues ciliogenesis in LCA patient cells.

Erin R Burnight; Luke A Wiley; Arlene V Drack; Terry A Braun; Kristin Anfinson; Emily E Kaalberg; Jennifer Halder; Robert Mullins; Edwin M Stone; Budd A Tucker

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3300. doi:

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