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Meeting Abstract (12)
Journal Articles (3)

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Investigative Ophthalmology & Visual Science (15)

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ARVO Annual Meeting Abstract (12)
Clinical and Epidemiologic Research (1)
Genetics (1)
Retinal Cell Biology (1)

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Eye Anatomy and Disorders (2)
Genetics (2)
Retina (2)
Clinical and Epidemiologic Research (1)
Retinal Cell Biology (1)

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dog, domestic (2)
retina (2)
axon (1)
axon guidance (1)
did not receive therapy or drug (1)
gene expression (1)
middle-aged adult (1)
neuroglia (1)
presynaptic terminals (1)
proteins (1)

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Clinical and Epidemiologic Research October 2024

Glial Cell Responses and Gene Expression Dynamics in Retinas of Treated and Untreated RPE65 Mutant Dogs

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Tatyana Appelbaum; Evelyn Santana; David A. Smith; William A. Beltran; Gustavo D. Aguirre
TAGS: did not receive therapy or drug, dog, domestic, retina, rpe65 protein, neuroglia, gene expression, middle-aged adult
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):18. https://doi.org/10.1167/iovs.65.12.18

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Adaptive glial cell and gene expression alterations in retinas of treated and untreated RPE65 mutant dogs

Tatyana Appelbaum; Evelyn Santana; David Smith; William A Beltran; Gustavo D Aguirre

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5322.

ARVO Annual Meeting Abstract June 2021

Reactive changes of retinal microglia, astrocytes, and Müller glial cells in canine model of retinal atrophy caused by the mutation in RPE65 gene.

Tatyana Appelbaum; Evelyn Santana; Kristin L. Gardiner; Gustavo D Aguirre

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1697.

Genetics December 2020

Candidate Genetic Modifiers for RPGR Retinal Degeneration

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Tatyana Appelbaum; Leonardo Murgiano; Doreen Becker; Evelyn Santana; Gustavo D. Aguirre

Invest. Ophthalmol. Vis. Sci.. 2020; 61(14):20. https://doi.org/10.1167/iovs.61.14.20

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Decrease in the level of axon guidance receptor ROBO1 in rod synaptic terminals is followed by axonal retraction.

Tatyana Appelbaum; Evelyn Santana; Gustavo D Aguirre

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1285.

ARVO Annual Meeting Abstract June 2020

AAV gene therapy restores ON-bipolar cell function in a canine model of LRIT3 -congenital stationary night blindness

Keiko Miyadera; Karolina Roszak; Ana Ripolles Garcia; Evelyn Santana; Sommer M Iffrig; Meike Visel; Leah Byrne; William A Beltran; John Gerard Flannery; Gustavo D Aguirre

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2298.

Retinal Cell Biology March 2020

Critical Decrease in the Level of Axon Guidance Receptor ROBO1 in Rod Synaptic Terminals Is Followed by Axon Retraction

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Tatyana Appelbaum; Evelyn Santana; Gustavo D. Aguirre
TAGS: axon, axon guidance, dog, domestic, presynaptic terminals, retina, rod photoreceptors, proteins
Invest. Ophthalmol. Vis. Sci.. 2020; 61(3):11. https://doi.org/10.1167/iovs.61.3.11

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

The sequence variants in the novel lncRNAs, ROBO1-AS and ROBO2-AS , correlate with phenotype severity in canine RPGR-XLPRA1

Tatyana Appelbaum; Leonardo Murgiano; Doreen Becker; Evelyn Santana; Gustavo D Aguirre

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3436.

ARVO Annual Meeting Abstract July 2018

A point mutation in the novel lncRNA, ROBO2-AS , correlates with phenotype severity in canine RPGR-XLPRA1

Tatyana Appelbaum; Leonardo Murgiano; Doreen Becker; Evelyn Santana; Gustavo D Aguirre

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2347.

ARVO Annual Meeting Abstract June 2017

Upregulation of pro-inflammatory genes accompanies photoreceptors demise in canine models of retinal degeneration

Tatyana Appelbaum; Evelyn Santana; Gustavo D Aguirre

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3587.

ARVO Annual Meeting Abstract September 2016

RPGRIP1 mutant dogs show variable cone ERG functions

Gautami Das; Evelyn Santana; Simone Iwabe; Gustavo D Aguirre; Keiko Miyadera

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):167.

ARVO Annual Meeting Abstract September 2016

A quantitative trait locus on canine chromosome 31 influences disease severity phenotype of XLPRA1

Tatyana Appelbaum; Doreen Becker; Evelyn Santana; Gustavo D Aguirre

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6569.

ARVO Annual Meeting Abstract June 2015

Early disease phenotype in canine RPGRORF15 model is characterized by strong up-regulation of pro-inflammatory genes and down-regulation of neuroretinal maintenance genes

Tatyana Appelbaum; William A Beltran; Evelyn Santana; Gustavo D Aguirre

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4648.

ARVO Annual Meeting Abstract June 2015

Cone structure and function in dogs with RPGRIP1 mutation

Gautami Das; Evelyn Santana; Simone Iwabe; Gustavo D Aguirre; Keiko Miyadera

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4653.

ARVO Annual Meeting Abstract April 2014

Molecular and immunohistochemical characterization of a canine model of complete congenital stationary night blindness (CSNB)

Gautami Das; Keiko Miyadera; Evelyn Santana; Gustavo D Aguirre; Mineo Kondo

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3288.

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Online ISSN: 1552-5783

Investigative Ophthalmology & Visual Science
Journal of Vision
Translational Vision Science & Technology

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Copyright © 2025 Association for Research in Vision and Ophthalmology.

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