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ARVO Annual Meeting Abstract June 2024

Identifying transcriptional networks regulating LIF-induced retinal protection

Frank M Dyka; John D Ash

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3939.

ARVO Annual Meeting Abstract June 2022

A modified arrestin1 increases lactate production in the retina and slows retinal degeneration

W. Clay Smith; Tiffany S Nelson; Chiab Simpson; Frank M Dyka; Astra Dinculescu

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):51 – A0024.

ARVO Annual Meeting Abstract June 2022

Transcription factor Nfe2l1 sets proteasomal levels in the retina

Yixiao Wang; Aaron Snell; Jyoti Jinde; Elizabeth Colvin; Frank M Dyka; Ekaterina Lobanova

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3876 – A0078.

ARVO Annual Meeting Abstract June 2021

Disease mechanisms of X-linked cone dystrophy caused by missense mutations in the red and green cone opsins

Wen-Tao Deng; Ping Zhu; Frank M Dyka; Wolfgang Baehr; William W Hauswirth

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1554.

ARVO Annual Meeting Abstract June 2020

A novel epitope-tagged Clarin-1 knock-in mouse with retinal dysfunction and profound congenital deafness

Astra Dinculescu; Omar Akil; Susan Bolch; Frank M Dyka; William N Ruddick; Chiab Simpson; Lei Xu

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2446.

ARVO Annual Meeting Abstract June 2020

Serotype dependent Adeno-Associated Virus Hybrid Vector mediated gene therapy for Stargardt Disease

Frank M Dyka; Vince A. Chiodo; William W Hauswirth

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2464.

ARVO Annual Meeting Abstract July 2019

Dual Adeno-Associated Virus Vector mediated gene therapy for autosomal recessive Stargardt Disease

Frank M Dyka; Laurie L Molday; Vince A Chiodo; Robert S Molday; William Hauswirth

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3402.

ARVO Annual Meeting Abstract July 2019

Functional Consequences and Cellular Distribution of C1QTNF5 Mutants in Murine Retinal Pigment Epithelium

Astra Dinculescu; Lei Xu; Susan N Bolch; Frank M Dyka; Ping Zhu; Hugh McDowell

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4899.

ARVO Annual Meeting Abstract July 2018

Dual Adeno-Associated Virus Vector Treatment of Autosomal Recessive Stargardt Disease

Frank M Dyka; William W Hauswirth

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4533.

ARVO Annual Meeting Abstract July 2018

Phenotypic consequences of amino acid substitutions at the S163 position in C1QTNF5 protein following expression in murine RPE

Astra Dinculescu; Susan Bolch; Frank M Dyka; Manoj Kulkarni; Chiab Simpson; W Clay Smith; William W Hauswirth

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3052.

ARVO Annual Meeting Abstract July 2018

The expression pattern and pathological effects of CLRN1 mutant proteins in the mouse retina

Susan Bolch; Frank M Dyka; Manoj Kulkarni; Rachel Stupay; Chiab Simpson; W Clay Smith; William W Hauswirth; Astra Dinculescu

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3053.

ARVO Annual Meeting Abstract June 2017

Adeno-associated virus dual vector-mediated gene therapy for ABCA4 Stargardt Disease

Frank M Dyka; Vince A Chiodo; William W Hauswirth

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4497.

ARVO Annual Meeting Abstract June 2017

RPE targeted overexpression of mutant S163R C1QTNF5 in various mouse models of RPE/photoreceptor dysfunction

Astra Dinculescu; Frank M Dyka; Seok-Hong Min; Rachel M Stupay; W. Clay Smith; William W Hauswirth

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5229.

ARVO Annual Meeting Abstract September 2016

Co-expression and interaction of wild-type and mutant C1QTNF5 in vivo : implications for gene-therapy

Astra Dinculescu; Frank M Dyka; Seok-Hong Min; Rachel Michelle Stupay; William W Hauswirth

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1173.

Retina October 2015

Pathological Effects of Mutant C1QTNF5 (S163R) Expression in Murine Retinal Pigment Epithelium

PDF

Astra Dinculescu; Seok-Hong Min; Frank M. Dyka; Wen-Tao Deng; Rachel M. Stupay; Vince Chiodo; W. Clay Smith; William W. Hauswirth
TAGS: antibodies, eye, immunohistochemistry, injections, mice, photoreceptors, proteins, retinal pigment epithelium, spatial vectors, tissue membrane
Invest. Ophthalmol. Vis. Sci.. 2015; 56(11):6971-6980. https://doi.org/10.1167/iovs.15-17166

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2015

AAV-mediated rescue of a mouse model of X-linked Congenital Stationary Night Blindness

Miranda White; Sanford L Boye; Frank M Dyka; Kathryn MH Fransen; Charles N de Leeuw; Elizabeth M. Simpson; Ronald G Gregg; Maureen A McCall; Neal S Peachey; Shannon Elizabeth Boye

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2036.

ARVO Annual Meeting Abstract April 2014

Over-expression of human mutant C1QTNF5 (Ser163Arg) in RPE cells leads to both RPE and photoreceptor cell loss in wild-type mice

Astra Dinculescu; Seok-Hong Min; Frank M Dyka; Renee C Ryals; Vince Chiodo; William W Hauswirth

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2188.

ARVO Annual Meeting Abstract April 2014

Dual AAV vector development for CEP290 -LCA

Renee C Ryals; Frank M Dyka; Jingfen Sun; Oliver Sroka; William W Hauswirth

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3329.

ARVO Annual Meeting Abstract April 2014

Characterization of fidelity of dual Adeno-associated virus vectors generated cDNA

Frank M Dyka; Sanford L Boye; William W Hauswirth; Shannon Boye

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3330.

ARVO Annual Meeting Abstract April 2014

Optimizing rAAV vectors to target ON bipolar cells

Miranda L White; Frank M Dyka; Charles N de Leeuw; Seok-Hong Min; Qing Ruan; Sanford L Boye; Neal S Peachey; Elizabeth M Simpson; William W Hauswirth; Shannon Boye

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3336.

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Identifying transcriptional networks regulating LIF-induced retinal protection

A modified arrestin1 increases lactate production in the retina and slows retinal degeneration

Transcription factor Nfe2l1 sets proteasomal levels in the retina

Disease mechanisms of X-linked cone dystrophy caused by missense mutations in the red and green cone opsins

A novel epitope-tagged Clarin-1 knock-in mouse with retinal dysfunction and profound congenital deafness

Serotype dependent Adeno-Associated Virus Hybrid Vector mediated gene therapy for Stargardt Disease

Dual Adeno-Associated Virus Vector mediated gene therapy for autosomal recessive Stargardt Disease

Functional Consequences and Cellular Distribution of C1QTNF5 Mutants in Murine Retinal Pigment Epithelium

Dual Adeno-Associated Virus Vector Treatment of Autosomal Recessive Stargardt Disease

Phenotypic consequences of amino acid substitutions at the S163 position in C1QTNF5 protein following expression in murine RPE

The expression pattern and pathological effects of CLRN1 mutant proteins in the mouse retina

Adeno-associated virus dual vector-mediated gene therapy for ABCA4 Stargardt Disease

RPE targeted overexpression of mutant S163R C1QTNF5 in various mouse models of RPE/photoreceptor dysfunction

Co-expression and interaction of wild-type and mutant C1QTNF5 in vivo : implications for gene-therapy

Pathological Effects of Mutant C1QTNF5 (S163R) Expression in Murine Retinal Pigment Epithelium

AAV-mediated rescue of a mouse model of X-linked Congenital Stationary Night Blindness

Over-expression of human mutant C1QTNF5 (Ser163Arg) in RPE cells leads to both RPE and photoreceptor cell loss in wild-type mice

Dual AAV vector development for CEP290 -LCA

Characterization of fidelity of dual Adeno-associated virus vectors generated cDNA

Optimizing rAAV vectors to target ON bipolar cells

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