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Refractive Intervention May 2025

Association Between Inflammatory Cytokines and Refractive Errors: A Bidirectional Mendelian Randomization Study

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Yue Xu; Xing-Xuan Dong; Yun Wang; Xin-Yu Zhuang; Ying-Jie Chen; Xiao-Feng Zhang; Chen-Wei Pan
TAGS: cytokine, mendelian randomization analysis, refractive errors, ciliary motility disorders
Trans. Vis. Sci. Tech.. 2025; 14(5):1. https://doi.org/10.1167/tvst.14.5.1

Includes: Supplemental Content

Lens April 2025

Macrophage-Hosted Porphyromonas gingivalis Is a Risk Factor for Cataract Development

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Dongzhe Zhang; Junwei Qu; Cuncun Ke; Xiumei Kong; Mengyun Liu; Iqbal Nawaz Khan; Shuxin Huang; Haijiao Tian; Tong Xie; Ke Qiu; Jing Li; Mingli Wang; Hui Li; Fengling Yuan; Weikai Guo; Mingya Cao; Jing Zhang; Keke Zhu; Jin Luo; Fengyan Zhang; Xiukun Cui; Hongmei Mu; Yanzhong Hu
TAGS: body tissue, cataract, epithelium, infections, lens (device), macrophages, risk factors, porphyromonas gingivalis, hypertension, lens, crystalline
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):68. https://doi.org/10.1167/iovs.66.4.68

Includes: Supplemental Content

Glaucoma February 2025

Robotic Visible-Light Optical Coherence Tomography Visualizes Segmental Schlemm's Canal Anatomy and Segmental Pilocarpine Response

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Raymond Fang; Pengpeng Zhang; Daniel Kim; Junghun Kweon; Cheng Sun; Alex S. Huang; Hao F. Zhang
TAGS: optical coherence tomography, pilocarpine, schlemm's canal, visible light, eye, diagnostic imaging, vaccine information sheets, language morphology, morphology
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):47. https://doi.org/10.1167/iovs.66.2.47

Glaucoma January 2025

In Vivo Quantification of Anterior and Posterior Chamber Volumes in Mice: Implications for Aqueous Humor Dynamics

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Daniel Kim; Raymond Fang; Pengpeng Zhang; Zihang Yan; Cheng Sun; Guorong Li; Christa Montgomery; Simon W. M. John; W. Daniel Stamer; Hao F. Zhang; C. Ross Ethier
TAGS: anterior chamber of eye, aqueous humor, diagnostic imaging, eye, mice, vaccine information sheets, volume, x-ray microtomography
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):18. https://doi.org/10.1167/iovs.66.1.18

Includes: Supplemental Content

Perspective December 2024

Consensus Recommendations for Studies of Outflow Facility and Intraocular Pressure Regulation Using Ex Vivo Perfusion Approaches

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Ted S. Acott; Michael P. Fautsch; Weiming Mao; C. Ross Ethier; Alex S. Huang; Mary J. Kelley; Mini Aga; Sanjoy K. Bhattacharya; Terete Borras; Diane Bovenkamp; Uttio Roy Chowdhury; Abbot F. Clark; Mohammed I. Dibas; Yiqin Du; Michael H. Elliott; Jennifer A. Faralli; Haiyan Gong; Samuel Herberg; Murray A. Johnstone; Paul L. Kaufman; Kate E. Keller; Ruth A. Kelly; David Krizaj; Markus H. Kuehn; Hoi Lam Li; Raquel Lieberman; Shan C. Lin; Yutao Liu; Fiona S. McDonnell; Colleen M. McDowell; Gillian J. McLellan; Philip Mzyk; Kayarat Saidas Nair; Darryl R. Overby; Donna M. Peters; VijayKrishna Raghunathan; Ponugoti Vasantha Rao; Gavin W. Roddy; Najam A. Sharif; Myoung Sup Shim; Yang Sun; Benjamin R. Thomson; Carol B. Toris; Colin E. Willoughby; Hao F. Zhang; Thomas F. Freddo; Rudolf Fuchshofer; Kamisha R. Hill; Alireza Karimi; Krishnakumar Kizhatil; Casey C. Kopcyznski; Paloma Liton; Gaurang Patel; Michael Peng; Padmanabhan P. Pattabiraman; Ganesh Prasanna; Ester Reina-Torres; E. Griffen Samples; John R. Samples; Cynthia L. Steel; Clemens A. Strohmaier; Preeti Subramanian; Chenna Kesavulu Sugali; Joseph van Batenburg-Sherwood; Cydney Wong; Hannah Youngblood; Gulab S. Zode; Elizabeth White; W. Daniel Stamer
TAGS: body tissue, eye, fluid flow, intraocular pressure, perfusion, regulation, organ culture techniques
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):32. https://doi.org/10.1167/iovs.65.14.32

Refractive Intervention July 2024

Accelerometer-Measured Daily Behaviors That Mediate the Association Between Refractive Status and Depressive Disorders

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Zijing Du; Shan Wang; Gabriella Bulloch; Feng Zhang; Yaxin Wang; Chunran Lai; Zhiyong Zhuo; Yu Huang; Xianwen Shang; Ying Fang; Zhuoting Zhu; Yijun Hu; Xiayin Zhang; Honghua Yu
TAGS: accelerometers, depressive disorders
Trans. Vis. Sci. Tech.. 2024; 13(7):3. https://doi.org/10.1167/tvst.13.7.3

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Effective treatment of optic neuropathies by intraocular delivery of MSC-sEVs through augmenting the G-CSF-macrophage pathway

Wei Yi; Ying Xue; Wenjie Qing; Yingxue Cao; Lingli Zhou; Mingming Xu; Zehui Sun; Yuying Li; Xiaomei Mai; Le Shi; Chang He; Feng Zhang; Elia J Duh; Yihai Cao; Xialin Liu

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):678.

ARVO Annual Meeting Abstract June 2024

Safety and Efficacy of AAV-mediated Gene Replacement Therapy in Bietti Crystalline Corneoretinal Dystrophy

Liping Yang; Jinyuan Wang; Jinlu Zhang; Shicheng Yu; Hongyan LI; Shaohong Chen; Fan Zhang; Jing Qiao; Baoyuan Qu; Wang Li; Haibo wang; Yuxia Guan; Haihan Zhang; Xiuli Zhao; Likun Wang; Wen-bin Wei

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3287.

ARVO Annual Meeting Abstract June 2024

RNFB Orientation Map with Visible Light OCT for Optic Neuropathy Detection

Weijia Fan; David Andrew Miller; Daniel Kim; Avram Bar-Meir; Harnaina Bains; Nicholas J Volpe; Shira Simon; Rukhsana Mirza; Hao F Zhang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5496.

ARVO Annual Meeting Abstract June 2024

Super-resolution imaging of whole mount RPE tissue

Xingyue Hao; Benjamin Brenner; Junghun Kweon; Hao F Zhang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1309.

ARVO Annual Meeting Abstract June 2024

In Vivo Visible-light Optical Coherence Tomography for Imaging the Full 360 Degrees of the Conventional Outflow Pathway

Raymond Fang; Pengpeng Zhang; Daniel Seunggi Kim; Cheng Sun; Junghun Kweon; Alex S Huang; Hao F Zhang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4265.

ARVO Annual Meeting Abstract June 2024

In vivo reconstruction of the anterior and posterior chamber of the mouse eye montaging volumes from visible-light optical coherence tomography

Daniel Seunggi Kim; Raymond Fang; Pengpeng Zhang; Cheng Sun; Hao F Zhang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5551.

ARVO Annual Meeting Abstract June 2024

Visible-Light Optical Coherence Tomography (Vis-OCT) compared to Fundus Autofluorescence (FAF), Swept-Source (SS)-OCT, and Spectral-Domain (SD)-OCT in Patients with Geographic Atrophy (GA)

Avram Bar-Meir; Weijia Fan; David Andrew Miller; joseph fahey; Harnaina Bains; Shira Simon; Nicholas J Volpe; Hao F Zhang; Rukhsana Mirza

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5915.

ARVO Annual Meeting Abstract June 2024

Hyperreflective dots in Central Fovea visualized by visible-light Optical Coherence Tomography Fibergraphy

Marta Grannonico; Micheal Krause; David Andrew Miller; Weijia Fan; Mingna Liu; Roman Kuranov; Peter Netland; Xiaorong Liu; Hao F Zhang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1436.

ARVO Annual Meeting Abstract June 2024

Longitudinal Dynamic Changes of RGC Axon Bundles in Mouse Silicone Oil-Induced Ocular Hypertension Glaucoma Model Revealed by Visible-light OCT Fibergraphy

Mingshen Ma; Weijia Fan; Liang Li; Hao F Zhang; Yang Hu

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2520.

ARVO Annual Meeting Abstract June 2024

NADPH oxidase 4-induced Endothelial Cell Senescence Contributes to Pericyte Loss in Diabetic Retinopathy

Sarah Xin Zhang; Jinli Wang; Benjamin Brenner; Hao F Zhang; Joshua J Wang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3835.

ARVO Annual Meeting Abstract June 2024

Vis-OCT Explorer: an open-source visualization package for visible-light optical coherence tomography

Fengyuanshan Xu; Weijia Fan; Raymond Fang; David Andrew Miller; Hao F Zhang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5948.

Cornea June 2024

Fosfenopril Attenuates Inflammatory Response in Diabetic Dry Eye Models by Inhibiting the TLR4/NF-κB/NLRP3 Signaling Pathway

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Kaiwen Jiang; Fenglan Zhang; Ying Chen; Xiaojing Li; Xinmei Zhao; Pengfei Jiang; Yuanbin Li
TAGS: diabetes mellitus, dry eye syndromes, glucose, nlr family, pyrin domain-containing 3 protein, signal pathway, signal transduction pathways, toll-like receptor 4, mice, cornea, inflammatory response
Invest. Ophthalmol. Vis. Sci.. 2024; 65(6):2. https://doi.org/10.1167/iovs.65.6.2

Glaucoma March 2024

Reduced Aqueous Humor Outflow Pathway Arborization in Childhood Glaucoma Eyes

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Shikha Gupta; Xiaowei Zhang; Arnav Panigrahi; Shakha; Raymond Fang; Clemens A. Strohmaier; Hao F. Zhang; Robert N. Weinreb; Viney Gupta; Alex S. Huang
TAGS: aqueous humor, eye, glaucoma, congenital, angiogram, adult, surgical procedures, operative, cataract
Trans. Vis. Sci. Tech.. 2024; 13(3):23. https://doi.org/10.1167/tvst.13.3.23

Includes: Supplemental Content

Immunology and Microbiology February 2024

SOX9 Induces Orbital Fibroblast Activation in Thyroid Eye Disease Via MAPK/ERK1/2 Pathway

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Min Zhou; Bingying Lin; Pengsen Wu; Yu Ke; Siyu Huang; Fan Zhang; Xiangqing Hei; Zhen Mao; Xingyi Li; Pengxia Wan; Tingting Chen; Huasheng Yang; Danping Huang
TAGS: fibroblasts, graves' ophthalmopathy, mitogen-activated protein kinases, sox9 gene, fibrosis
Invest. Ophthalmol. Vis. Sci.. 2024; 65(2):25. https://doi.org/10.1167/iovs.65.2.25

Includes: Supplemental Content

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Association Between Inflammatory Cytokines and Refractive Errors: A Bidirectional Mendelian Randomization Study

Macrophage-Hosted Porphyromonas gingivalis Is a Risk Factor for Cataract Development

Robotic Visible-Light Optical Coherence Tomography Visualizes Segmental Schlemm's Canal Anatomy and Segmental Pilocarpine Response

In Vivo Quantification of Anterior and Posterior Chamber Volumes in Mice: Implications for Aqueous Humor Dynamics

Consensus Recommendations for Studies of Outflow Facility and Intraocular Pressure Regulation Using Ex Vivo Perfusion Approaches

Accelerometer-Measured Daily Behaviors That Mediate the Association Between Refractive Status and Depressive Disorders

Effective treatment of optic neuropathies by intraocular delivery of MSC-sEVs through augmenting the G-CSF-macrophage pathway

Safety and Efficacy of AAV-mediated Gene Replacement Therapy in Bietti Crystalline Corneoretinal Dystrophy

RNFB Orientation Map with Visible Light OCT for Optic Neuropathy Detection

Super-resolution imaging of whole mount RPE tissue

In Vivo Visible-light Optical Coherence Tomography for Imaging the Full 360 Degrees of the Conventional Outflow Pathway

In vivo reconstruction of the anterior and posterior chamber of the mouse eye montaging volumes from visible-light optical coherence tomography

Visible-Light Optical Coherence Tomography (Vis-OCT) compared to Fundus Autofluorescence (FAF), Swept-Source (SS)-OCT, and Spectral-Domain (SD)-OCT in Patients with Geographic Atrophy (GA)

Hyperreflective dots in Central Fovea visualized by visible-light Optical Coherence Tomography Fibergraphy

Longitudinal Dynamic Changes of RGC Axon Bundles in Mouse Silicone Oil-Induced Ocular Hypertension Glaucoma Model Revealed by Visible-light OCT Fibergraphy

NADPH oxidase 4-induced Endothelial Cell Senescence Contributes to Pericyte Loss in Diabetic Retinopathy

Vis-OCT Explorer: an open-source visualization package for visible-light optical coherence tomography

Fosfenopril Attenuates Inflammatory Response in Diabetic Dry Eye Models by Inhibiting the TLR4/NF-κB/NLRP3 Signaling Pathway

Reduced Aqueous Humor Outflow Pathway Arborization in Childhood Glaucoma Eyes

SOX9 Induces Orbital Fibroblast Activation in Thyroid Eye Disease Via MAPK/ERK1/2 Pathway

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