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Meeting Abstract (51)
Journal Articles (6)

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Investigative Ophthalmology & Visual Science (57)

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ARVO Annual Meeting Abstract (51)
Retinal Cell Biology (4)
Physiology and Pharmacology (1)
Retina (1)

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Eye Anatomy and Disorders (5)
Genetics (5)
Immunology and Microbiology (4)
Retina (4)
Retinal Cell Biology (4)
Biochemistry and Molecular Biology (2)
Cornea (1)
Imaging (1)
Pharmacology (1)
Retinal Imaging (1)
Visual Neuroscience (1)

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proteins (2)
rna, messenger (2)
triamcinolone acetonide (2)
vascular endothelial growth factor a (2)
angiogenesis (1)
catabolism (1)
cobalt (1)
cornea (1)
dna, complementary (1)
electroretinography (1)

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ARVO Annual Meeting Abstract June 2024

DJ-1 mitigates hypoxic stress in oxygen-induced retinopathy mouse model

Mala Upadhyay; Paul Freedman; George Hoppe; Jonathan E Sears; Vera L Bonilha

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):295.

ARVO Annual Meeting Abstract June 2024

A/J Mice Protection from OIR is Associated with Aryl Hydrocarbon Receptor Activity

Kevin Fung; George Hoppe; Demiana Hanna; Ke Jiang; Andrew Dale Benos; Jonathan E Sears

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):294.

ARVO Annual Meeting Abstract June 2024

HIF stabilization by Roxadustat may condition retinal cells to withstand hyperoxic insult via metabolic adaptation.

Andrew Dale Benos; George Hoppe; Jonathan E Sears

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):271.

ARVO Annual Meeting Abstract June 2023

Hepatic HIF Stabilization by Novel Carbonyl Glycine Derivatives Protects Against Oxygen-Induced Retinopathy

Christie Kay Campla; George Hoppe; Demiana Hanna; Andrew Dale Benos; Vara Prasad Josyula; Shaun Stauffer; Juliana Woda; Jonathan E Sears

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):579.

ARVO Annual Meeting Abstract June 2023

HIF Stabilization Induces Reductive Carboxylation

Andrew Dale Benos; George Hoppe; Demiana Hanna; Christie Kay Campla; Jonathan E Sears

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1607.

ARVO Annual Meeting Abstract June 2022

A unified model of hyperoxia of prematurity: systemic HIF stabilization protects developing vasculature of the eye and brain

Weilin Song; Demiana Hanna; Andrew Benos; George Hoppe; Tara DeSilva; Jonathan Sears

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):277 – F0322.

ARVO Annual Meeting Abstract June 2022

Hepatic HIF-1 stabilization increases retinal and brain serine/1-carbon metabolism

Andrew Dale Benos; George Hoppe; Demiana Hanna; Weilin Song; Allison B Grenell; Bela Anand-Apte; Jonathan Sears

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4142 – F0379.

ARVO Annual Meeting Abstract June 2022

Near infrared photobiomodulation prevents neovascularization in oxygen-induced retinopathy in mouse

Rupesh Singh; George Hoppe; Demiana Hanna; Zoe Miller; Paul Freedman; Vera L Bonilha; Bela Anand-Apte; Jonathan Sears

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4133 – F0370.

ARVO Annual Meeting Abstract June 2021

A two-step model of PVL and ROP

Weilin Song; George Hoppe; Demiana Hanna; Jonathan E Sears

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3001.

ARVO Annual Meeting Abstract June 2020

Retinal metabolic remodeling and hepatic nitrogen imbalance in oxygen induced retinopathy (OIR)

Charandeep Singh; Andrew Benos; Vincent Tran; Leah McCollum; Youstina Bolok; Hanna Demiana; Kristin Allan; Alex Yuan; George Hoppe; Henri Brunengraber; Jonathan E Sears

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5405.

ARVO Annual Meeting Abstract July 2019

Müller Cell HIF-2 is Not Required for Protection Against Oxygen Induced Retinopathy by Prolyl Hydroxylase Inhibition

George Hoppe; Youstina Bolok; Leah McCollum; Charandeep Singh; Jonathan E Sears

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1655.

ARVO Annual Meeting Abstract July 2018

3-Hydroxypyruvate accumulates in the retina of newborn mice exposed to hyperoxia and may contribute to angiostasis

Amit Sharma; Charandeep Singh; Weilin Song; Youstina Bolok; Jin Zhang; George Hoppe; Jonathan E Sears

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5462.

ARVO Annual Meeting Abstract July 2018

Serine metabolism is a key pathway involved in the prevention of oxygen-induced retinopathy by Roxadustat

Charandeep Singh; Amit Sharma; George Hoppe; Henri Brunengraber; Jonathan E Sears

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5464.

Retina July 2018

3-Hydroxypyruvate Destabilizes Hypoxia Inducible Factor and Induces Angiostasis

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Charandeep Singh; Amit Sharma; George Hoppe; Weilin Song; Youstina Bolok; Jonathan E. Sears
TAGS: hypoxia, metabolites, pyruvates
Invest. Ophthalmol. Vis. Sci.. 2018; 59(8):3440-3448. https://doi.org/10.1167/iovs.18-24120

ARVO Annual Meeting Abstract June 2017

Efficacy of novel hypoxia inducible factor-prolyl hydroxylase (HIF-PH) inhibitor in the prevention of retinopathy of prematurity (ROP)

Jin Zhang; George Hoppe; John Wang; Youstina Bolok; Amit Sharma; Jonathan E Sears

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3465.

ARVO Annual Meeting Abstract September 2016

Comparative Systems Pharmacology of HIF Stabilization in the Prevention of Retinopathy of Prematurity

George Hoppe; Suzy Yoon; Banu Gopalan; Rebecca Brown; Kelsey Case; Amit Vasanji; Ernest Ricky Chan; Jonathan E Sears

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3631.

ARVO Annual Meeting Abstract September 2016

Incidence of ROP After SUPPORT

Jonathan E Sears; Christine Sonnie; George Hoppe

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6287.

ARVO Annual Meeting Abstract June 2015

Pharmacological Stabilization of Hypoxia Inducible Factor 1 by FG 4592 Prevents Oxygen Induced Retinopathy

Jonathan E Sears; Suzy Yoon; Rebecca Brown; Kelsey Case; George Hoppe; Retina Cell Biology

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3634.

ARVO Annual Meeting Abstract June 2015

HIF stabilization in the liver prevents ROP by secreting hepatokines capable of promoting metabolic switch in retinal endothelium

George Hoppe; Suzy Yoon; Banu Gopalan; Rebecca Brown; Kelsey Case; Richard E Morton; Jonathan E Sears

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3643.

ARVO Annual Meeting Abstract June 2015

IFIT3/P60 Expression Reflects Cell Specific Response to Viral Infection

Nathaniel Sears; Steffen Christoffersen; George Hoppe; Jonathan E Sears

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):838.

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Online ISSN: 1552-5783

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Translational Vision Science & Technology

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