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ARVO Annual Meeting Abstract June 2022

Secreted frizzled-related protein (SFRP) serves as a potent antiangiogenic factor

Xiaomeng Wang; Beiying Qiu; Alison Tan; Amutha Veluchamy; Sze Yuan Ho; Lei Zhou; Ning Cheung; Gemmy Cheung Chui Ming; Tien Wong; Wanjin Hong

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):781 – F0340. doi:

Articles November 2021

Three-Year Outcomes of Neovascular Age-Related Macular Degeneration in Eyes That Do Not Develop Macular Atrophy or Subretinal Fibrosis

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Pierre-Henry Gabrielle; Vuong Nguyen; Jennifer J. Arnold; Sanjeeb Bhandari; Francesco Viola; Odette A. M. Tigchelaar-Besling; Gonzaga Garay-Aramburu; Louise O'Toole; Chui Ming Gemmy Cheung; Daniel Barthelmes; Catherine Creuzot-Garcher; Mark Gillies
TAGS: atrophoderma maculatum, exudative age-related macular degeneration, eye, fibrosis
Trans. Vis. Sci. Tech.. 2021; 10(13):5. doi: https://doi.org/10.1167/tvst.10.13.5

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2021

Causal Association of Serum Cholesterol Efflux Capacity and Polypoidal Choroidal Vasculopathy of Singapore Chinese Population

Yasuo Yanagi; Richard Yu Ming Chuan; Waseem Ahamed Shihabuddeen; Kelvin Yi Chong Teo; Anna CS Tan; Ching-Yu Cheng; Tien Y Wong; Gemmy Chui Ming Cheung

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2732. doi:

ARVO Annual Meeting Abstract June 2021

Detailed phenotypic investigation of HtrA1 transgenic mice model

Waseem Ahamed Shihabuddeen; Yasuo Yanagi; Richard Yu Ming Chuan; Veluchamy A Barathi; Xiaomeng Wang; Gemmy Chui Ming Cheung

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):268. doi:

ARVO Annual Meeting Abstract June 2021

HAWK and HARRIER 48-week data: potential for treatment interval extension in patients with nAMD disease activity at Week 16

Ramin Tadayoni; Glenn J Jaffe; Frank G Holz; Ursula Schmidt-Erfurth; Kanji Takahashi; Gemmy Chui Ming Cheung; Seenu Hariprasad; Kinfemichael Gedif; Rasmus Olsen; Catherine Best; Peter K Kaiser

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):426. doi:

Retina June 2021

Association of Aberrant Posterior Vitreous Detachment and Pathologic Tractional Forces With Myopic Macular Degeneration

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Kai Yuan Tey; Qiu Ying Wong; Yee Shan Dan; Andrew S. H. Tsai; Daniel S. W. Ting; Marcus Ang; Gemmy Chiu Ming Cheung; Shu Yen Lee; Tien Yin Wong; Quan V. Hoang; Chee Wai Wong
TAGS: eye, myopic macular degeneration, staphyloma, vitreous detachment, traction, medication therapy management, macular disorders, prevalence
Invest. Ophthalmol. Vis. Sci.. 2021; 62(7):7. doi: https://doi.org/10.1167/iovs.62.7.7

Special Issue May 2021

IMI Pathologic Myopia

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Kyoko Ohno-Matsui; Pei-Chang Wu; Kenji Yamashiro; Kritchai Vutipongsatorn; Yuxin Fang; Chui Ming Gemmy Cheung; Timothy Y. Y. Lai; Yasushi Ikuno; Salomon Yves Cohen; Alain Gaudric; Jost B. Jonas
TAGS: eye, macular disorders, myopia, myopic macular degeneration, staphyloma, macula lutea
Invest. Ophthalmol. Vis. Sci.. 2021; 62(5):5. doi: https://doi.org/10.1167/iovs.62.5.5

Includes: Supplemental Content

Retina March 2021

Choroidal and Retinal Changes After Systemic Adrenaline and Photodynamic Therapy in Non-Human Primates

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Kai Xiong Cheong; Veluchamy Amutha Barathi; Kelvin Yi Chong Teo; Usha Chakravarthy; Sai Bo Bo Tun; Joanna Marie Busoy; Candice Ee Hua Ho; Rupesh Agrawal; Kanji Takahashi; Chui Ming Gemmy Cheung
TAGS: epinephrine, photochemotherapy, primates
Invest. Ophthalmol. Vis. Sci.. 2021; 62(3):25. doi: https://doi.org/10.1167/iovs.62.3.25

Retina January 2021

Diabetic Macular Ischemia: Influence of Optical Coherence Tomography Angiography Parameters on Changes in Functional Outcomes Over One Year

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Andrew S. H. Tsai; Janice Marie Jordan-Yu; Alfred T. L. Gan; Kelvin Y. C. Teo; Gavin S. W. Tan; Shu Yen Lee; Victor Chong; Chui Ming Gemmy Cheung

Invest. Ophthalmol. Vis. Sci.. 2021; 62(1):9. doi: https://doi.org/10.1167/iovs.62.1.9

Includes: Supplemental Content

Articles July 2020

Intravitreal Injection with a Conjunctival Injection Device: A Single-Center Experience

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Yu Qiang Soh; Nathalie Pei Yu Chiam; Andrew Shih Hsiang Tsai; Gemmy Chui Ming Cheung; Tien Yin Wong; Ian Yew San Yeo; Edmund Yick Mun Wong; Anna Cheng Sim Tan
TAGS: conjunctival injection, injections, intravitreal injections, surgeons
Trans. Vis. Sci. Tech.. 2020; 9(8):28. doi: https://doi.org/10.1167/tvst.9.8.28

ARVO Annual Meeting Abstract June 2020

Handheld chromatic pupillometry detects preclinical retinal dysfunction in patients with diabetes mellitus

Tien-En Tan; Maxwell T Finkelstein; Gavin SW Tan; Anna Tan; Choi Mun Chan; Ranjana Mathur; Edmund YM Wong; Gemmy Cheung; Tien Yin Wong; Dan Milea; Raymond Najjar

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5039. doi:

ARVO Annual Meeting Abstract June 2020

Ocular and Systemic Associations of a 6-Year Change in OCT-derived Drusen Volume in the Singapore Chinese Eye Study

Anna CS Tan; Beau Fenner; Miao Li Chee; Yih Chung Tham; Ching-Yu Cheng; Gemmy Cheung; Tien Yin Wong

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4188. doi:

ARVO Annual Meeting Abstract June 2020

The role of a novel regulator of Wnt signalling in ocular angiogenesis

Beiying Qiu; Alison Tan; Veluchamy A Barathi; Sze Yuan Ho; Zhou Lei; Ning Cheung; Gemmy Cheung; Tien Yin Wong; Wanjin Hong; Xiaomeng Wang

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4443. doi:

ARVO Annual Meeting Abstract June 2020

Investigating the role of PPARβ/δ in retinal angiogenesis

Sze Yuan Ho; Beiying Qiu; Yuet Ping Kwan; Gemmy Cheung; Tien Yin Wong; Walter Arthur Wahli; Wanjin Hong; Xiaomeng Wang

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5414. doi:

ARVO Annual Meeting Abstract June 2020

Blood metabolomics and major eye diseases: the Singapore Epidemiology of Eye Diseases Study

Simon Nusinovici; Zhou Lei; Caroline Fajoles Vasseneix; Baskaran Mani; Yih Chung Tham; Gavin SW Tan; Gemmy Cheung; Charumathi Sabanayagam; Tien Y Wong; Ching-Yu Cheng

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):757. doi:

Clinical and Epidemiologic Research April 2020

Six-Year Changes in Myopic Macular Degeneration in Adults of the Singapore Epidemiology of Eye Diseases Study

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Yee-Ling Wong; Charumathi Sabanayagam; Chee-Wai Wong; Yin-Bun Cheung; Ryan Eyn Kidd Man; Anna Chwee-Hong Yeo; Gemmy Cheung; Audrey Chia; Anthony Kuo; Marcus Ang; Kyoko Ohno-Matsui; Tien-Yin Wong; Jie Jin Wang; Ching-Yu Cheng; Quan V. Hoang; Ecosse Lamoureux; Seang-Mei Saw
TAGS: adult, epidemiology, eye, eye diseases, incidence, myopic macular degeneration, singapore, risk factors, follow-up, fundus photography
Invest. Ophthalmol. Vis. Sci.. 2020; 61(4):14. doi: https://doi.org/10.1167/iovs.61.4.14

Clinical and Epidemiologic Research November 2019

Macular Vessel Density Measured With Optical Coherence Tomography Angiography and Its Associations in a Large Population-Based Study

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Qi Sheng You; Jonathan C. H. Chan; Alex L. K. Ng; Bonnie K. N. Choy; Kendrick C. Shih; Janice J. C. Cheung; Jasper K. W. Wong; Jennifer W. H. Shum; Michael Y. Ni; Jimmy S. M. Lai; Gabriel M. Leung; Chui Ming Gemmy Cheung; Tien Yin Wong; Ian Y. H. Wong
TAGS: angiogram, optical coherence tomography, retinal vessels
Invest. Ophthalmol. Vis. Sci.. 2019; 60(14):4830-4837. doi: https://doi.org/10.1167/iovs.19-28137

Retina July 2019

Apratoxin S4 Inspired by a Marine Natural Product, a New Treatment Option for Ocular Angiogenic Diseases

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Beiying Qiu; Alison Tan; Amutha Barathi Veluchamy; Yong Li; Hannah Murray; Wei Cheng; Chenghao Liu; Joanna Marie Busoy; Qi-Yin Chen; Srivani Sistla; Walter Hunziker; Chui Ming Gemmy Cheung; Tien Yin Wong; Wanjin Hong; Hendrik Luesch; Xiaomeng Wang
TAGS: angiogenesis, mice, natural products, aflibercept, neovascularization, pathologic, vascular endothelial growth factor a
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):3254-3263. doi: https://doi.org/10.1167/iovs.19-26936

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Artificial intelligence using a deep learning system with transfer learning to predict refractive error and myopic macular degeneration from color fundus photographs

Tien-En Tan; Daniel SW Ting; Yong Liu; Shaohua Li; Cheng Chen; Quang Nguyen; Chee Wai Wong; Quan V Hoang; Shu Yen Lee; Edmund Yick Mun Wong; Ian Yew San Yeo; Yee Ling Wong; Ching-Yu Cheng; Seang-Mei Saw; Gemmy Chui Ming Cheung; Tien Yin Wong

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1478. doi:

ARVO Annual Meeting Abstract July 2019

The role of a novel metabolic regulator in human retinal pigment epithelial cell function

Sze Yuan Ho; Beiying Qiu; Gemmy Chui Ming Cheung; Tien Yin Wong; Wan Jin Hong; Xiaomeng Wang

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1947. doi:

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Secreted frizzled-related protein (SFRP) serves as a potent antiangiogenic factor

Three-Year Outcomes of Neovascular Age-Related Macular Degeneration in Eyes That Do Not Develop Macular Atrophy or Subretinal Fibrosis

Causal Association of Serum Cholesterol Efflux Capacity and Polypoidal Choroidal Vasculopathy of Singapore Chinese Population

Detailed phenotypic investigation of HtrA1 transgenic mice model

HAWK and HARRIER 48-week data: potential for treatment interval extension in patients with nAMD disease activity at Week 16

Association of Aberrant Posterior Vitreous Detachment and Pathologic Tractional Forces With Myopic Macular Degeneration

IMI Pathologic Myopia

Choroidal and Retinal Changes After Systemic Adrenaline and Photodynamic Therapy in Non-Human Primates

Diabetic Macular Ischemia: Influence of Optical Coherence Tomography Angiography Parameters on Changes in Functional Outcomes Over One Year

Intravitreal Injection with a Conjunctival Injection Device: A Single-Center Experience

Handheld chromatic pupillometry detects preclinical retinal dysfunction in patients with diabetes mellitus

Ocular and Systemic Associations of a 6-Year Change in OCT-derived Drusen Volume in the Singapore Chinese Eye Study

The role of a novel regulator of Wnt signalling in ocular angiogenesis

Investigating the role of PPARβ/δ in retinal angiogenesis

Blood metabolomics and major eye diseases: the Singapore Epidemiology of Eye Diseases Study

Six-Year Changes in Myopic Macular Degeneration in Adults of the Singapore Epidemiology of Eye Diseases Study

Macular Vessel Density Measured With Optical Coherence Tomography Angiography and Its Associations in a Large Population-Based Study

Apratoxin S4 Inspired by a Marine Natural Product, a New Treatment Option for Ocular Angiogenic Diseases

Artificial intelligence using a deep learning system with transfer learning to predict refractive error and myopic macular degeneration from color fundus photographs

The role of a novel metabolic regulator in human retinal pigment epithelial cell function

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