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ARVO Annual Meeting Abstract July 2019

Treatment of diabetic mice with chromophore improves visual function and decreases oxidative stress and apoptosis in the retina

Gennadiy P Moiseyev; Volha Malechka; Rui Cheng; Jianglei Chen; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2659. doi:

ARVO Annual Meeting Abstract July 2018

A Novel non-Retinoid RPE65 Inhibitor CU239 Prevents Light-Induced Degeneration of the Mouse Retina through Slowing of the Visual Cycle

Gennadiy P Moiseyev; Younghwa Shin; Yusuke Takahashi; Konstantin Petrukhin; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5330. doi:

Retina September 2017

Transgenic Mice Over-Expressing RBP4 Have RBP4-Dependent and Light-Independent Retinal Degeneration

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Mei Du; Eric Phelps; Michael J. Balangue; Aaron Dockins; Gennadiy Moiseyev; Younghwa Shin; Shelley Kane; Laura Otalora; Jian-Xing Ma; Rafal Farjo; Krysten M. Farjo
TAGS: mice, retinal degeneration, mice, transgenic, electroretinography, retinoids
Invest. Ophthalmol. Vis. Sci.. 2017; 58(10):4375-4383. doi: https://doi.org/10.1167/iovs.17-22107

ARVO Annual Meeting Abstract June 2017

D477G dominant mutation in RPE65 leads to decreased 11- cis -retinal generation and delayed dark-adaptation in knock-in mouse model of retinitis pigmentosa

Gennadiy P Moiseyev; Younghwa Shin; Dibyendu Charkraborty; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):590. doi:

ARVO Annual Meeting Abstract June 2017

Impaired Retinoid Visual Cycle in Diabetic Retinopathy

Volha Malechka; Gennadiy P Moiseyev; Yusuke Takahashi; Younghwa Shin; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5226. doi:

Anatomy and Pathology/Oncology September 2016

Postnatal Chick Choroids Exhibit Increased Retinaldehyde Dehydrogenase Activity During Recovery From Form Deprivation Induced Myopia

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Angelica R. Harper; Xiang Wang; Gennadiy Moiseyev; Jian-Xing Ma; Jody A. Summers
TAGS: body tissue, choroid, myopia, oxidoreductase, proteins, recovery of function, retinaldehyde, tretinoin, western blotting, eye
Invest. Ophthalmol. Vis. Sci.. 2016; 57(11):4886-4897. doi: https://doi.org/10.1167/iovs.16-19395

ARVO Annual Meeting Abstract September 2016

Fenofibrate is a competitive inhibitor of the RPE65 isomerase

Gennadiy P Moiseyev; Younghwa Shin; Yusuke Takahashi; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1749. doi:

ARVO Annual Meeting Abstract September 2016

RPE-specific knock-out of Retinol Dehydrogenase 10 altered retinoid profile

Younghwa Shin; Gennadiy P Moiseyev; Krysten M Farjo; Yusuke Takahashi; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3621. doi:

ARVO Annual Meeting Abstract September 2016

Characterization of a novel retinaldehyde dehydrogenase selective inhibitor

Angelica Harper; Tim Mather; Anh Le; Anthony Burgett; Gennadiy P Moiseyev; John Moore; Jody A Summers Rada

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

ARVO Annual Meeting Abstract September 2016

The impact of diabetes on the retinoid metabolism in the eye

Volha Malechka; Gennadiy P Moiseyev; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5433. doi:

ARVO Annual Meeting Abstract June 2015

Transgenic Mice Over-Expressing Serum Retinol-Binding Protein have Progressive Inner Retinal Degeneration Caused by a Retinoid-Independent Mechanism

Krysten M Farjo; Laura Otalora; Mei Du; Ashley Martin; Gennadiy P Moiseyev; Phillip Vanlandingham; Rafal Farjo; Alexander Quiambao

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5425. doi:

ARVO Annual Meeting Abstract June 2015

Human carboxylesterase 1 is expressed in retinal pigment epithelium and hydrolyzes retinyl ester

Gennadiy P Moiseyev; Yusuke Takahashi; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5506. doi:

ARVO Annual Meeting Abstract June 2015

Increased retinaldehyde dehydrogenase activity during recovery from induced myopia

Angelica Harper; Gennadiy P Moiseyev; Jody Ann Summers

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5845. doi:

ARVO Annual Meeting Abstract April 2014

A Mutant of RPE65 D477G Affects Subcellular Localization of Wild-type RPE65 by Formation of Protein Complexes

Younghwa Shin; Olga Nikolaeva; Gennadiy P Moiseyev; Yusuke Takahashi; Jian-Xing Ma

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):6333. doi:

ARVO Annual Meeting Abstract April 2014

Identification of Key Residues Enhancing Isomerohydrolase Activity of Human RPE65 for More Efficient Gene Therapy

Yusuke Takahashi; Gennadiy P Moiseyev; Jian-Xing Ma

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3476. doi:

ARVO Annual Meeting Abstract April 2014

Identification and in vitro Characterization of Novel Non-retinoid RPE65 Inhibitors

Gennadiy P Moiseyev; Jian-Xing Ma; Konstantin Petrukhin

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3477. doi:

ARVO Annual Meeting Abstract June 2013

Cloning and Characterization of a Carboxylesterase from Bovine Retinal Pigment Epithelium

Gennadiy Moiseyev; Bill Wu; Yusuke Takahashi; Ying Chen; Andrew Tsin; Rosalie Crouch; Jian-Xing Ma

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):3760. doi:

ARVO Annual Meeting Abstract June 2013

Mechanism for a Dominant-Acting D477G Mutation in RPE65 Leading to Vision Impairment

Olga Nikolaeva; Gennadiy Moiseyev; Yusuke Takahashi; Jian-Xing Ma

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):3762. doi:

ARVO Annual Meeting Abstract June 2013

Targeting the STRA6/RBP4 Binding interaction to Treat Macular Degeneration

Krysten Farjo; Gennadiy Moiseyev; Jian-Xing Ma

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):1702. doi:

Translational Research January 2013

A1120, a Nonretinoid RBP4 Antagonist, Inhibits Formation of Cytotoxic Bisretinoids in the Animal Model of Enhanced Retinal Lipofuscinogenesis

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Nicoleta Dobri; Qiong Qin; Jian Kong; Kazunori Yamamoto; Zhao Liu; Gennadiy Moiseyev; Jian-xing Ma; Rando Allikmets; Janet R. Sparrow; Konstantin Petrukhin
TAGS: animal model, antagonists, fenretinide, mice, retinoids, vitamin a, lipofuscin, retina
Invest. Ophthalmol. Vis. Sci.. 2013; 54(1):85-95. doi: https://doi.org/10.1167/iovs.12-10050

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Treatment of diabetic mice with chromophore improves visual function and decreases oxidative stress and apoptosis in the retina

A Novel non-Retinoid RPE65 Inhibitor CU239 Prevents Light-Induced Degeneration of the Mouse Retina through Slowing of the Visual Cycle

Transgenic Mice Over-Expressing RBP4 Have RBP4-Dependent and Light-Independent Retinal Degeneration

D477G dominant mutation in RPE65 leads to decreased 11- cis -retinal generation and delayed dark-adaptation in knock-in mouse model of retinitis pigmentosa

Impaired Retinoid Visual Cycle in Diabetic Retinopathy

Postnatal Chick Choroids Exhibit Increased Retinaldehyde Dehydrogenase Activity During Recovery From Form Deprivation Induced Myopia

Fenofibrate is a competitive inhibitor of the RPE65 isomerase

RPE-specific knock-out of Retinol Dehydrogenase 10 altered retinoid profile

Characterization of a novel retinaldehyde dehydrogenase selective inhibitor

The impact of diabetes on the retinoid metabolism in the eye

Transgenic Mice Over-Expressing Serum Retinol-Binding Protein have Progressive Inner Retinal Degeneration Caused by a Retinoid-Independent Mechanism

Human carboxylesterase 1 is expressed in retinal pigment epithelium and hydrolyzes retinyl ester

Increased retinaldehyde dehydrogenase activity during recovery from induced myopia

A Mutant of RPE65 D477G Affects Subcellular Localization of Wild-type RPE65 by Formation of Protein Complexes

Identification of Key Residues Enhancing Isomerohydrolase Activity of Human RPE65 for More Efficient Gene Therapy

Identification and in vitro Characterization of Novel Non-retinoid RPE65 Inhibitors

Cloning and Characterization of a Carboxylesterase from Bovine Retinal Pigment Epithelium

Mechanism for a Dominant-Acting D477G Mutation in RPE65 Leading to Vision Impairment

Targeting the STRA6/RBP4 Binding interaction to Treat Macular Degeneration

A1120, a Nonretinoid RBP4 Antagonist, Inhibits Formation of Cytotoxic Bisretinoids in the Animal Model of Enhanced Retinal Lipofuscinogenesis

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