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ARVO Annual Meeting Abstract June 2024

PNPLA3 deficiency increases 11- cis -retinal regeneration in the visual cycle

Miwa Hara; Volha V. Malechka; Wenjing Lily wu; Yusuke Takahashi; Jian-Xing (Jay) Ma; Gennadiy P Moiseyev

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):186.

ARVO Annual Meeting Abstract June 2024

RPE65 Regulates Retinal Energy Metabolism

Rui Cheng; Miwa Hara; Wenjing Lily wu; Gennadiy P Moiseyev; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1297.

ARVO Annual Meeting Abstract June 2024

Exploring the Therapeutic Potential of Salivary Exosomes in Corneal Epithelial Wound Healing

Wentao Liang; Sarah E Nicholas; Tian Yuan; Rui Cheng; Yusuke Takahashi; Gennadiy P Moiseyev; Dimitrios Karamichos; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6170.

Cornea August 2023

A Method for Real-Time Assessment of Mitochondrial Respiration Using Murine Corneal Biopsy

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Wentao Liang; Li Huang; Tian Yuan; Rui Cheng; Yusuke Takahashi; Gennadiy P. Moiseyev; Dimitrios Karamichos; Jian-Xing Ma
TAGS: biopsy, cornea, mice, mitochondria, respiration
Invest. Ophthalmol. Vis. Sci.. 2023; 64(11):33. https://doi.org/10.1167/iovs.64.11.33

ARVO Annual Meeting Abstract June 2023

PNPLA2 promotes 11- cis- retinol regeneration in the visual cycle

Miwa Hara; Wenjing Wu; Yusuke Takahashi; Jian-Xing Ma; Gennadiy P Moiseyev

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5198.

ARVO Annual Meeting Abstract June 2022

A novel non-retinoid visual cycle inhibitor RPE65-61 protects the retinal photoreceptors from light-induced degeneration

Gennadiy P Moiseyev; Yuhong Wang; Xiang Ma; Parthasarathy Muthuraman; Arun Raja; Aravindan Jayaraman; Konstantin Petrukhin; Christopher Cioffi; Jian-Xing Ma

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1773 – F0322.

ARVO Annual Meeting Abstract June 2022

PNPLA2 mobilizes retinyl esters from retinosomes in the retinal pigment epithelium

Miwa Hara; Wenjing Wu; Yusuke Takahashi; Jian-Xing Ma; Gennadiy P Moiseyev

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2483 – F0190.

ARVO Annual Meeting Abstract June 2022

The interplay of luminance and genetics in the retinopathy induced by the dominant RPE65 mutation

Wenjing Wu; Yusuke Takahashi; Xiang Ma; Gennadiy P Moiseyev; Jian-Xing Ma

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):460.

ARVO Annual Meeting Abstract July 2019

Treatment of diabetic mice with chromophore improves visual function and decreases oxidative stress and apoptosis in the retina

Gennadiy P Moiseyev; Volha Malechka; Rui Cheng; Jianglei Chen; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2659.

ARVO Annual Meeting Abstract July 2018

A Novel non-Retinoid RPE65 Inhibitor CU239 Prevents Light-Induced Degeneration of the Mouse Retina through Slowing of the Visual Cycle

Gennadiy P Moiseyev; Younghwa Shin; Yusuke Takahashi; Konstantin Petrukhin; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5330.

Retina September 2017

Transgenic Mice Over-Expressing RBP4 Have RBP4-Dependent and Light-Independent Retinal Degeneration

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Mei Du; Eric Phelps; Michael J. Balangue; Aaron Dockins; Gennadiy Moiseyev; Younghwa Shin; Shelley Kane; Laura Otalora; Jian-Xing Ma; Rafal Farjo; Krysten M. Farjo
TAGS: mice, retinal degeneration, mice, transgenic, electroretinography, retinoids
Invest. Ophthalmol. Vis. Sci.. 2017; 58(10):4375-4383. https://doi.org/10.1167/iovs.17-22107

ARVO Annual Meeting Abstract June 2017

D477G dominant mutation in RPE65 leads to decreased 11- cis -retinal generation and delayed dark-adaptation in knock-in mouse model of retinitis pigmentosa

Gennadiy P Moiseyev; Younghwa Shin; Dibyendu Charkraborty; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):590.

ARVO Annual Meeting Abstract June 2017

Impaired Retinoid Visual Cycle in Diabetic Retinopathy

Volha Malechka; Gennadiy P Moiseyev; Yusuke Takahashi; Younghwa Shin; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5226.

ARVO Annual Meeting Abstract September 2016

Fenofibrate is a competitive inhibitor of the RPE65 isomerase

Gennadiy P Moiseyev; Younghwa Shin; Yusuke Takahashi; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1749.

ARVO Annual Meeting Abstract September 2016

Characterization of a novel retinaldehyde dehydrogenase selective inhibitor

Angelica Harper; Tim Mather; Anh Le; Anthony Burgett; Gennadiy P Moiseyev; John Moore; Jody A Summers Rada

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12)

ARVO Annual Meeting Abstract September 2016

The impact of diabetes on the retinoid metabolism in the eye

Volha Malechka; Gennadiy P Moiseyev; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5433.

ARVO Annual Meeting Abstract September 2016

RPE-specific knock-out of Retinol Dehydrogenase 10 altered retinoid profile

Younghwa Shin; Gennadiy P Moiseyev; Krysten M Farjo; Yusuke Takahashi; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3621.

Anatomy and Pathology/Oncology September 2016

Postnatal Chick Choroids Exhibit Increased Retinaldehyde Dehydrogenase Activity During Recovery From Form Deprivation Induced Myopia

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Angelica R. Harper; Xiang Wang; Gennadiy Moiseyev; Jian-Xing Ma; Jody A. Summers
TAGS: body tissue, choroid, myopia, oxidoreductase, proteins, recovery of function, retinaldehyde, tretinoin, western blotting, eye
Invest. Ophthalmol. Vis. Sci.. 2016; 57(11):4886-4897. https://doi.org/10.1167/iovs.16-19395

ARVO Annual Meeting Abstract June 2015

Transgenic Mice Over-Expressing Serum Retinol-Binding Protein have Progressive Inner Retinal Degeneration Caused by a Retinoid-Independent Mechanism

Krysten M Farjo; Laura Otalora; Mei Du; Ashley Martin; Gennadiy P Moiseyev; Phillip Vanlandingham; Rafal Farjo; Alexander Quiambao

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5425.

ARVO Annual Meeting Abstract June 2015

Human carboxylesterase 1 is expressed in retinal pigment epithelium and hydrolyzes retinyl ester

Gennadiy P Moiseyev; Yusuke Takahashi; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5506.

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PNPLA3 deficiency increases 11- cis -retinal regeneration in the visual cycle

RPE65 Regulates Retinal Energy Metabolism

Exploring the Therapeutic Potential of Salivary Exosomes in Corneal Epithelial Wound Healing

A Method for Real-Time Assessment of Mitochondrial Respiration Using Murine Corneal Biopsy

PNPLA2 promotes 11- cis- retinol regeneration in the visual cycle

A novel non-retinoid visual cycle inhibitor RPE65-61 protects the retinal photoreceptors from light-induced degeneration

PNPLA2 mobilizes retinyl esters from retinosomes in the retinal pigment epithelium

The interplay of luminance and genetics in the retinopathy induced by the dominant RPE65 mutation

Treatment of diabetic mice with chromophore improves visual function and decreases oxidative stress and apoptosis in the retina

A Novel non-Retinoid RPE65 Inhibitor CU239 Prevents Light-Induced Degeneration of the Mouse Retina through Slowing of the Visual Cycle

Transgenic Mice Over-Expressing RBP4 Have RBP4-Dependent and Light-Independent Retinal Degeneration

D477G dominant mutation in RPE65 leads to decreased 11- cis -retinal generation and delayed dark-adaptation in knock-in mouse model of retinitis pigmentosa

Impaired Retinoid Visual Cycle in Diabetic Retinopathy

Fenofibrate is a competitive inhibitor of the RPE65 isomerase

Characterization of a novel retinaldehyde dehydrogenase selective inhibitor

The impact of diabetes on the retinoid metabolism in the eye

RPE-specific knock-out of Retinol Dehydrogenase 10 altered retinoid profile

Postnatal Chick Choroids Exhibit Increased Retinaldehyde Dehydrogenase Activity During Recovery From Form Deprivation Induced Myopia

Transgenic Mice Over-Expressing Serum Retinol-Binding Protein have Progressive Inner Retinal Degeneration Caused by a Retinoid-Independent Mechanism

Human carboxylesterase 1 is expressed in retinal pigment epithelium and hydrolyzes retinyl ester

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