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Retina April 2025

Fluorescence Lifetime Imaging Ophthalmoscopy, Vision, and Chorioretinal Asymmetries in Aging and Age-Related Macular Degeneration: ALSTAR2

PDF

Lukas Goerdt; Mark E. Clark; Tracy N. Thomas; Liyan Gao; Gerald McGwin, Jr.; Martin Hammer; Jason N. Crosson; Kenneth R. Sloan; Cynthia Owsley; Christine A. Curcio
TAGS: age-related macular degeneration, aging, diagnostic imaging, eye, fluorescence, ophthalmoscopy, vision, cohort studies
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):56. https://doi.org/10.1167/iovs.66.4.56

Includes: Supplemental Content

Retina March 2025

Topographic Analysis of Two-Wavelength Autofluorescence Supports Higher Macular Xanthophyll Pigment in AMD Than Aging: ALSTAR2 Baseline

PDF

Lukas Goerdt; Andreas Berlin; Liyan Gao; Thomas A. Swain; Sarah S. Kim; Gerald McGwin; Mark E. Clark; Deepayan Kar; Cynthia Owsley; Kenneth R. Sloan; Christine A. Curcio
TAGS: aging, autofluorescence, eye, lutein, pigment, maps, meridians, diagnostic imaging
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):61. https://doi.org/10.1167/iovs.66.3.61

Includes: Supplemental Content

Retina December 2024

Band Visibility in High-Resolution Optical Coherence Tomography Assessed With a Custom Review Tool and Updated, Histology-Derived Nomenclature

PDF

Lukas Goerdt; Thomas A. Swain; Deepayan Kar; Gerald McGwin; Andreas Berlin; Mark E. Clark; Cynthia Owsley; Kenneth R. Sloan; Christine A. Curcio
TAGS: eye, histology, optical coherence tomography, retina, software, reliability, volume electron microscopy, diagnostic imaging
Trans. Vis. Sci. Tech.. 2024; 13(12):19. https://doi.org/10.1167/tvst.13.12.19

Includes: Multimedia, Supplemental Content

Retina August 2024

Extent and Topography of Subretinal Drusenoid Deposits Associate With Rod-Mediated Vision in Aging and AMD: ALSTAR2 Baseline

PDF

Lukas Goerdt; Mohymina Amjad; Thomas A. Swain; Gerald McGwin; Mark E. Clark; Cynthia Owsley; Kenneth R. Sloan; Christine A. Curcio; Deepayan Kar
TAGS: digestive tract decontamination, rod photoreceptors, vision, eye, aging
Invest. Ophthalmol. Vis. Sci.. 2024; 65(10):25. https://doi.org/10.1167/iovs.65.10.25

Includes: Supplemental Content

Multidisciplinary Ophthalmic Imaging July 2024

Choriocapillaris Impairment, Visual Function, and Distance to Fovea in Aging and Age-Related Macular Degeneration: ALSTAR2 Baseline

PDF

Deepayan Kar; Mohymina Amjad; Giulia Corradetti; Thomas A. Swain; Mark E. Clark; Gerald McGwin, Jr.; Kenneth R. Sloan; Cynthia Owsley; SriniVas R. Sadda; Christine A. Curcio
TAGS: age-related macular degeneration, aging, fovea centralis, vision, impairment, rod photoreceptors, eye
Invest. Ophthalmol. Vis. Sci.. 2024; 65(8):40. https://doi.org/10.1167/iovs.65.8.40

ARVO Annual Meeting Abstract June 2024

Artificial Intelligence Ready and Equitable Atlas for Diabetes Insights (AI-READI) study: Report on recruitment strategy and pilot data collection

Alina Ferguson; Cari Drolet; Trina Kim; Cath Ashley; Julia Owen; Missy Takahashi; Dawn Mathies; Shay Paselio; Sally Liu Baxter; Aaron Y Lee; Linda M Zangwill; Cecilia S Lee; Gerald McGwin; Cynthia Owsley

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3727.

ARVO Annual Meeting Abstract June 2024

Outer Retinal Thickness is Associated with Cognitive Function in Normal Aging to Intermediate Age-related Macular Degeneration (AMD)

Cynthia Owsley; Gerald McGwin; Thomas A. Swain; Mark E Clark; Tracy N Thomas; Lucas Goerdt; Kenneth R Sloan; Emily Trittschuh; Yu Jiang; Julia Owen; Cecilia S Lee; Christine A Curcio

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2267.

ARVO Annual Meeting Abstract June 2024

Generation of a Multimodal Atlas of Type 2 Diabetes for Artificial Intelligence (AI-READI): Purpose and Design

Dawn Matthies; Julia Owen; Gerald McGwin; Cynthia Owsley; Sally Liu Baxter; Linda M Zangwill; Cecilia S Lee; Aaron Y Lee

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3728.

ARVO Annual Meeting Abstract June 2024

Thinning of outer retina is associated with decreased hippocampal volume and cortical thinning in Alzheimer’s disease related areas

Yu Jiang; Thomas A. Swain; Christine Mac Donald; Ariel Rokem; Julia P Owen; Gerald McGwin; Christine A Curcio; Kenneth R Sloan; Emily H Trittschuh; Swati Rane Levendovszky; Mark E Clark; Cynthia Owsley; Cecilia S Lee

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):446.

ARVO Annual Meeting Abstract June 2024

Validation of the Low Luminance Questionnaire (LLQ) in Normal Aging and Early and Intermediate Age-related Macular Degeneration (AMD)

Thomas A. Swain; Scott S Snyder; Catherine A Cukras; Christine A Curcio; Gerald McGwin; Cynthia Owsley

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3343.

ARVO Annual Meeting Abstract June 2024

Rod-mediated dark adaptation (RMDA) at 5° is correlated with subretinal drusenoid deposit (SDD) area in eyes with and without age-related macular degeneration (AMD): ALSTAR2 baseline

Mohymina Amjad; Thomas A. Swain; Gerald McGwin; Kenneth R Sloan; Cynthia Owsley; Christine A Curcio; Deepayan Kar

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2295.

Retina May 2024

Outer Retinal Thickness Is Associated With Cognitive Function in Normal Aging to Intermediate Age-Related Macular Degeneration

PDF

Cynthia Owsley; Gerald McGwin, Jr.; Thomas A. Swain; Mark E. Clark; Tracy N. Thomas; Lukas Goerdt; Kenneth R. Sloan; Emily H. Trittschuh; Yu Jiang; Julia P. Owen; Cecilia S. Lee; Christine A. Curcio
TAGS: age-related macular degeneration, aging, cognition, cognitive ability, mental processes, retina, eye
Invest. Ophthalmol. Vis. Sci.. 2024; 65(5):16. https://doi.org/10.1167/iovs.65.5.16

Multidisciplinary Ophthalmic Imaging September 2023

Choriocapillaris Impairment Is Associated With Delayed Rod-Mediated Dark Adaptation in Age-Related Macular Degeneration

PDF

Deepayan Kar; Giulia Corradetti; Thomas A. Swain; Mark E. Clark; Gerald McGwin, Jr.; Cynthia Owsley; SriniVas R. Sadda; Christine A. Curcio
TAGS: age-related macular degeneration, dark adaptation, drusen, eye, fluid flow, impairment, rod photoreceptors, vision, visual impairment, diagnostic imaging
Invest. Ophthalmol. Vis. Sci.. 2023; 64(12):41. https://doi.org/10.1167/iovs.64.12.41

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

Does foveal pit morphology contribute to age-related macular degeneration (AMD)? tool development utilizing ALSTAR2 baseline imaging data

Andreas Berlin; Mark E. Clark; Thomas A. Swain; Gerald McGwin; Cynthia Owsley; Jason Neal Crosson; Kenneth R Sloan; Christine A. Curcio

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5005.

ARVO Annual Meeting Abstract June 2023

Antidepressant medication use is associated with impaired rod-mediated visual functions in normal aging and early and intermediate AMD: ALSTAR2 baseline

Thomas A. Swain; Mark E. Clark; Christine A. Curcio; Cynthia Owsley; Gerald McGwin

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5068.

ARVO Annual Meeting Abstract June 2023

Defining the macular xanthophyll pigment (MXP) distribution pattern by automating centration in dual wavelength autofluorescence(2WAF): ALSTAR2 baseline cohort

Kenneth R Sloan; Andreas Berlin; Mark E. Clark; Thomas A. Swain; Gerald McGwin; Jason Neal Crosson; Cynthia Owsley; Christine A. Curcio

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5021.

ARVO Annual Meeting Abstract June 2023

Choriocapillaris flow impairment under the fovea is associated with delayed rod-mediated dark adaptation in the perifovea of eyes with early and intermediate age-related macular degeneration: ALSTAR2 baseline

Deepayan Kar; Giulia Corradetti; Mohymina Amjad; Thomas A. Swain; Mark E. Clark; Gerald McGwin; Cynthia Owsley; Kenneth R Sloan; SriniVas R Sadda; Christine A. Curcio

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):921.

Retina October 2022

Impact of the Aging Lens and Posterior Capsular Opacification on Quantitative Autofluorescence Imaging in Age-Related Macular Degeneration

PDF

Andreas Berlin; Mark E. Clark; Thomas A. Swain; Nathan A. Fischer; Gerald McGwin, Jr; Kenneth R. Sloan; Cynthia Owsley; Christine A. Curcio
TAGS: age-related macular degeneration, aging, autofluorescence, diagnostic imaging, eye, lens (device), lens, crystalline, opacification, pseudophakia
Trans. Vis. Sci. Tech.. 2022; 11(10):23. https://doi.org/10.1167/tvst.11.10.23

Includes: Supplemental Content

Retina July 2022

How Vision Is Impaired From Aging to Early and Intermediate Age-Related Macular Degeneration: Insights From ALSTAR2 Baseline

PDF

Cynthia Owsley; Thomas A. Swain; Gerald McGwin, Jr.; Mark E. Clark; Deepayan Kar; Jason N. Crosson; Christine A. Curcio
TAGS: age-related macular degeneration, aging, eye, vision, digestive tract decontamination
Trans. Vis. Sci. Tech.. 2022; 11(7):17. https://doi.org/10.1167/tvst.11.7.17

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

The AL-SIGHT Program: Evaluating Change in Patient Knowledge about Glaucoma and Attitudes about Eye Care

Lindsay Anne Rhodes; Ellen Antwi-Adjei; Thomas A. Swain; Gerald McGwin; Angela Harbour; Shilpa Register; Irfan Asif; Christopher A Girkin; Cynthia Owsley

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2157 – A0185.

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Fluorescence Lifetime Imaging Ophthalmoscopy, Vision, and Chorioretinal Asymmetries in Aging and Age-Related Macular Degeneration: ALSTAR2

Topographic Analysis of Two-Wavelength Autofluorescence Supports Higher Macular Xanthophyll Pigment in AMD Than Aging: ALSTAR2 Baseline

Band Visibility in High-Resolution Optical Coherence Tomography Assessed With a Custom Review Tool and Updated, Histology-Derived Nomenclature

Extent and Topography of Subretinal Drusenoid Deposits Associate With Rod-Mediated Vision in Aging and AMD: ALSTAR2 Baseline

Choriocapillaris Impairment, Visual Function, and Distance to Fovea in Aging and Age-Related Macular Degeneration: ALSTAR2 Baseline

Artificial Intelligence Ready and Equitable Atlas for Diabetes Insights (AI-READI) study: Report on recruitment strategy and pilot data collection

Outer Retinal Thickness is Associated with Cognitive Function in Normal Aging to Intermediate Age-related Macular Degeneration (AMD)

Generation of a Multimodal Atlas of Type 2 Diabetes for Artificial Intelligence (AI-READI): Purpose and Design

Thinning of outer retina is associated with decreased hippocampal volume and cortical thinning in Alzheimer’s disease related areas

Validation of the Low Luminance Questionnaire (LLQ) in Normal Aging and Early and Intermediate Age-related Macular Degeneration (AMD)

Rod-mediated dark adaptation (RMDA) at 5° is correlated with subretinal drusenoid deposit (SDD) area in eyes with and without age-related macular degeneration (AMD): ALSTAR2 baseline

Outer Retinal Thickness Is Associated With Cognitive Function in Normal Aging to Intermediate Age-Related Macular Degeneration

Choriocapillaris Impairment Is Associated With Delayed Rod-Mediated Dark Adaptation in Age-Related Macular Degeneration

Does foveal pit morphology contribute to age-related macular degeneration (AMD)? tool development utilizing ALSTAR2 baseline imaging data

Antidepressant medication use is associated with impaired rod-mediated visual functions in normal aging and early and intermediate AMD: ALSTAR2 baseline

Defining the macular xanthophyll pigment (MXP) distribution pattern by automating centration in dual wavelength autofluorescence(2WAF): ALSTAR2 baseline cohort

Choriocapillaris flow impairment under the fovea is associated with delayed rod-mediated dark adaptation in the perifovea of eyes with early and intermediate age-related macular degeneration: ALSTAR2 baseline

Impact of the Aging Lens and Posterior Capsular Opacification on Quantitative Autofluorescence Imaging in Age-Related Macular Degeneration

How Vision Is Impaired From Aging to Early and Intermediate Age-Related Macular Degeneration: Insights From ALSTAR2 Baseline

The AL-SIGHT Program: Evaluating Change in Patient Knowledge about Glaucoma and Attitudes about Eye Care

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