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ARVO Annual Meeting Abstract June 2024

Comparative Evaluation of Anti-Angiogenic Effects of Biosimilar Drugs in a DL-α-Aminoadipic Acid Rabbit Model of Chronic Vascular Leakage in Retina.

Donatas Neverauskas; Robertas Cesna; Symantas Ragauskas; Tomas Paulauskas; Giedrius Kalesnykas; Jeffrey Adam Jamison; Odeta Adamoniene

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):712.

ARVO Annual Meeting Abstract June 2024

Neural Network-based Isolectin B 4 Flat-Mount Analysis in a Novel AAV-hVEGF-Induced Diabetic Retinopathy Animal Model

Inesa Lelyte; Symantas Ragauskas; Marius Dragasius; Zubair Ahmed; Giedrius Kalesnykas; Nerija Kvietkauskiene

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2333.

ARVO Annual Meeting Abstract June 2024

Function-Structure Relationship in the Rat Glaucoma Model

Kernius Mickevicius; Tomas Paulauskas; Robertas Cesna; Marius Dragasius; Justina Urbanaviciute; Symantas Ragauskas; Giedrius Kalesnykas

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6758.

ARVO Annual Meeting Abstract June 2023

Optomotor reflex in the mouse optic nerve crush model for glaucomatous optic neuropathies

Maria Vähätupa; Anni Tenhunen; Leena Tähtivaara; Niina Jääskeläinen; Päivi Partanen; Anni Kolehmainen; Birgitta Lappeteläinen; Heidi Koskenniemi; Pinja Mertano; Ville Jokinen; Nerija Kvietkauskiene; Simas Bijeikis; Jonas Jarutis; Giedrius Kalesnykas; Marc Cerrada-Gimenez; Simon Kaja

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4709.

ARVO Annual Meeting Abstract June 2023

Suprachoroidal administration of aflibercept protects against neovascularization in the mouse CNV model

Marc Cerrada-Gimenez; Maria Vähätupa; Birgitta Lappeteläinen; Leena Tähtivaara; Ville Jokinen; Anne Mari Haapaniemi; Olga Vergun; Nerija Kvietkauskiene; Simas Bijeikis; Jonas Jarutis; Anni Kolehmainen; Pinja Mertano; Emmi Sarkola; Giedrius Kalesnykas; Simon Kaja

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2233.

ARVO Annual Meeting Abstract June 2023

Aflibercept exerts structural protection against diabetic retinopathy-associated inner retinal abnormalities in the mouse STZ model

Symantas Ragauskas; Tomas Paulauskas; Inesa Lelyte; Donatas Neverauskas; Kernius Mickevicius; Robertas Cesna; Giedrius Kalesnykas; Simon Kaja

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):556.

ARVO Annual Meeting Abstract June 2023

AAV-mediated expression of human VEGF-A as a novel rat model of diabetic retinopathy

Inesa Lelyte; Symantas Ragauskas; Tomas Paulauskas; Zubair Ahmed; Simon Kaja; Giedrius Kalesnykas

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1820.

ARVO Annual Meeting Abstract June 2023

Involvement of thioredoxin system in laser induced CNV mouse model

Robertas Cesna; Dovile Litvinaviciute; Justina Urbanaviciute; Inesa Lelyte; Kernius Mickevicius; Odeta Adamoniene; Donatas Neverauskas; Symantas Ragauskas; Giedrius Kalesnykas; Anita K. Ghosh; Simon Kaja

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2727.

ARVO Annual Meeting Abstract June 2022

Visual behaviour-based screening of a randomised chemical library identifies small molecules that restore vision.

Breandan N Kennedy; John Fehilly; Marc Cerrada-Gimenez; Simon Kaja; Giedrius Kalesnykas; Robert Scoffin; Justine O'Brien

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):680 – F0134.

ARVO Annual Meeting Abstract June 2022

Comparison of the laser-induced choroidal neovascularization model pathology in C57BL/6J mice from different vendors

Maria Vähätupa; Giedrius Kalesnykas; Ville Jokinen; Teemu Nevalainen; Leena Tähtivaara; Rubina Thapa; Heidi Koskenniemi; Anni Tenhunen; Birgitta Lappeteläinen; Anne Mari Haapaniemi; Nerija Kvietkauskiene; Jonas Jarutis; Simas Bijeikis; Simon Kaja; Marc Cerrada-Gimenez

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3032 – F0403.

ARVO Annual Meeting Abstract June 2022

Title. Development of human retinal pigment epithelial cells with inducible VEGF expression

Inesa Lelyte; Vidhya R. Rao; Zubair Ahmed; Giedrius Kalesnykas; Simon Kaja

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3608 – A0063.

ARVO Annual Meeting Abstract June 2021

Extracellular vesicles (exosomes) derived from primary optic nerve head astrocytes enhance neurite outgrowth.

Simon Kaja; Harsh Nilesh Hariani; Anita K. Ghosh; Giedrius Kalesnykas; Walter Keith Jones

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1651.

ARVO Annual Meeting Abstract June 2021

Validation of a novel artificial intelligence (AI) machine learning algorithm for quantification of vascular pathology in preclinical models

Jonas Jarutis; Simas Bijeikis; Symantas Ragauskas; Kernius Mickevicius; Giedrius Kalesnykas; Marc Cerrada-Gimenez; Simon Kaja; Nerija Kvietkauskiene

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2718.

ARVO Annual Meeting Abstract June 2020

Longitudinal characterization of the Cln8 mnd mouse model of CLN8 Batten Disease.

Marc Cerrada-Gimenez; Giedrius Kalesnykas; Kimmo Lehtimäki; Timmo Bragge; Jukka Puoliväli; Jussi Rytkönen; Pekka Poutiainen; Tyler Johnson; Jacob Cain; Samantha Davis; Antti Nurmi; Jill Weimer

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2240.

ARVO Annual Meeting Abstract June 2020

Xanthohumol protects corneal epithelial cells in experimental models for dry-eye disease

Anita K. Ghosh; Rubina Thapa; Harsh Nilesh Hariani; Agne Ziniauskaite; Samatha Ankireddy; Karoline A Orloff; Jenni J. Hakkarainen; Giedrius Kalesnykas; Kelly Langert; Simon Kaja

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3257.

ARVO Annual Meeting Abstract June 2020

Automated quantification of CNV volume using deep learning AI algorithm

Maria Vähätupa; Symantas Ragauskas; Agne Ziniauskaite; Anna Knuuttila; Hanna-Kaisa Sihvo; Mikael Jääskeläinen; Simon Kaja; Giedrius Kalesnykas; Marc Cerrada-Gimenez

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4194.

ARVO Annual Meeting Abstract June 2020

Comparative efficacy of bevacizumab and aflibercept in the rabbit DL-AAA model of chronic retinal neovascularization

Robertas Cesna; Tomas Paulauskas; Kernius Mickevicius; Donatas Neverauskas; Inesa Lelyte; Simon Kaja; Giedrius Kalesnykas; Symantas Ragauskas

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5391.

ARVO Annual Meeting Abstract June 2020

Characterization of VEGF-induced retinal neovascularization in Dutch Belted rabbits using in vivo imaging.

Donatas Neverauskas; Kernius Mickevičius; Simon Kaja; Giedrius Kalesnykas; Symantas Ragauskas

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5399.

ARVO Annual Meeting Abstract July 2019

Standardization and validation of intravitreal and systemic administration of aflibercept in preclinical models for angiogenesis

Simon Kaja; Symantas Ragauskas; Maria Vähätupa; Marc Cerrada-Gimenez; Satu Mering; Jenni J. Hakkarainen; Giedrius Kalesnykas

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1629.

ARVO Annual Meeting Abstract July 2019

Comparison and validation of ex vivo and in vitro corneal permeability models

Jenni J. Hakkarainen; Agne Ziniauskaite; Vytautas Cepla; Ramunas Valiokas; Giedrius Kalesnykas

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5087.

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Comparative Evaluation of Anti-Angiogenic Effects of Biosimilar Drugs in a DL-α-Aminoadipic Acid Rabbit Model of Chronic Vascular Leakage in Retina.

Neural Network-based Isolectin B 4 Flat-Mount Analysis in a Novel AAV-hVEGF-Induced Diabetic Retinopathy Animal Model

Function-Structure Relationship in the Rat Glaucoma Model

Optomotor reflex in the mouse optic nerve crush model for glaucomatous optic neuropathies

Suprachoroidal administration of aflibercept protects against neovascularization in the mouse CNV model

Aflibercept exerts structural protection against diabetic retinopathy-associated inner retinal abnormalities in the mouse STZ model

AAV-mediated expression of human VEGF-A as a novel rat model of diabetic retinopathy

Involvement of thioredoxin system in laser induced CNV mouse model

Visual behaviour-based screening of a randomised chemical library identifies small molecules that restore vision.

Comparison of the laser-induced choroidal neovascularization model pathology in C57BL/6J mice from different vendors

Title. Development of human retinal pigment epithelial cells with inducible VEGF expression

Extracellular vesicles (exosomes) derived from primary optic nerve head astrocytes enhance neurite outgrowth.

Validation of a novel artificial intelligence (AI) machine learning algorithm for quantification of vascular pathology in preclinical models

Longitudinal characterization of the Cln8 mnd mouse model of CLN8 Batten Disease.

Xanthohumol protects corneal epithelial cells in experimental models for dry-eye disease

Automated quantification of CNV volume using deep learning AI algorithm

Comparative efficacy of bevacizumab and aflibercept in the rabbit DL-AAA model of chronic retinal neovascularization

Characterization of VEGF-induced retinal neovascularization in Dutch Belted rabbits using in vivo imaging.

Standardization and validation of intravitreal and systemic administration of aflibercept in preclinical models for angiogenesis

Comparison and validation of ex vivo and in vitro corneal permeability models

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