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Cornea November 2018

Assessment of Topical Therapies for Improving the Optical Clarity Following Stromal Wounding in a Novel Ex Vivo Canine Cornea Model

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William M. Berkowski; Daniel J. Gibson; SooJung Seo; Laura R. Proietto; R. David Whitley; Gregory S. Schultz; Caryn E. Plummer
TAGS: cornea, corneal opacity, dog, domestic, fibrosis, optics, pirfenidone, vorinostat, wounds and injuries, epithelialization, placebos
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5509-5521. https://doi.org/10.1167/iovs.17-23085

ARVO Annual Meeting Abstract September 2016

Assessment of topical therapies for improving optical clarity following stromal wounding in a novel ex vivo canine cornea model.

William Michael Berkowski; Daniel J Gibson; Laura Proietto; David David Whitley; Gregory S Schultz; Caryn Plummer

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5714.

ARVO Annual Meeting Abstract June 2015

Localized AAV-PEDF gene transfer reduces corneal neovascularization significantly in rabbits in vivo via selective apoptosis

Rajiv R Mohan; Ajay Sharma; Elizabeth A Giuliano; Prashant Sinha; Jason T Rodier; Gregory S Schultz; Jonathan C K Tovey

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4509.

ARVO Annual Meeting Abstract June 2015

PUT THE PRESERVATIVE IN THE BOTTLE, NOT IN THE EYE!

Richard A Eiferman; Gregory S Schultz; Bernd Liesenfeld; Chris batich

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5728.

ARVO Annual Meeting Abstract June 2015

Development and assessment of a novel ex vivo canine model of corneal epithelial wound healing

R David Whitley; Laura Proietto; Dennis E Brooks; Gregory S Schultz; Daniel J Gibson; William M. Berkowski; Caryn Plummer

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3458.

ARVO Annual Meeting Abstract April 2014

CTGF Binds To Growth Factors Of The Cysteine Knot Superfamily And Is Critical For Corneal Wound Healing Through Modulation Of PDGF-B Signaling

Liya Pi; Pei-Yu Chung; Daniel J Gibson; Sriniwas Sriram; Paulette Marie Robinson; Mohammed M Rahman; Edward Scott; Bryon Petersen; Gregory S Schultz

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):4696.

ARVO Annual Meeting Abstract April 2014

Targeted Smad7 gene transfer into stroma attenuates corneal scarring

Ajay Sharma; Lisa L Leishman; Gregory S Schultz; Rajiv R Mohan

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):5153.

ARVO Annual Meeting Abstract April 2014

Tissue-Specific Knockout of Connective Tissue Growth Factor in the Cornea and Lens Epithelia Results in an Aniridia-Like Phenotype

Daniel J Gibson; Liya Pi; Gregory S Schultz

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):5495.

Cornea April 2014

Conditional Knockout of CTGF Affects Corneal Wound Healing

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Daniel J. Gibson; Liya Pi; Sriniwas Sriram; Cong Mao; Bryon E. Petersen; Edward W. Scott; Andrew Leask; Gregory S. Schultz
TAGS: connective tissue growth factor, cornea, wound healing
Invest. Ophthalmol. Vis. Sci.. 2014; 55(4):2062-2070. https://doi.org/10.1167/iovs.13-12735

Cornea December 2013

Triple Combination of siRNAs Targeting TGFβ1, TGFβR2, and CTGF Enhances Reduction of Collagen I and Smooth Muscle Actin in Corneal Fibroblasts

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Sriniwas Sriram; Paulette Robinson; Liya Pi; Alfred S. Lewin; Gregory Schultz
TAGS: actins, cicatrix, collagen, connective tissue growth factor, cornea, fibroblasts, rna, small interfering, smooth muscle, proteins, gene expression
Invest. Ophthalmol. Vis. Sci.. 2013; 54(13):8214-8223. https://doi.org/10.1167/iovs.13-12758

Includes: Supplemental Content

Biochemistry and Molecular Biology October 2013

MicroRNA Signature in Wound Healing Following Excimer Laser Ablation: Role of miR-133b on TGFβ1, CTGF, SMA, and COL1A1 Expression Levels in Rabbit Corneal Fibroblasts

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Paulette M. Robinson; Tsai-Der Chuang; Sriniwas Sriram; Liya Pi; Xiao Ping Luo; Bryon E. Petersen; Gregory S. Schultz
TAGS: ablation, connective tissue growth factor, cornea, fibroblasts, micrornas, oryctolagus cuniculus, wound healing, excimer lasers, polymerase chain reaction
Invest. Ophthalmol. Vis. Sci.. 2013; 54(10):6944-6951. https://doi.org/10.1167/iovs.13-12621

Cornea July 2013

The Progression of Haze Formation in Rabbit Corneas Following Phototherapeutic Keratectomy

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Daniel J. Gibson; Sonal S. Tuli; Gregory S. Schultz
TAGS: cornea, corneal opacity, oryctolagus cuniculus, wounds and injuries
Invest. Ophthalmol. Vis. Sci.. 2013; 54(7):4776-4781. https://doi.org/10.1167/iovs.13-11976

ARVO Annual Meeting Abstract June 2013

Nanoparticle Vectored siRNAs Reduce Profibrotic Gene Expression in Wounded Rabbit Corneas

Sriniwas Sriram; Paulette Robinson; Alfred Lewin; Gregory Schultz

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):3878.

ARVO Annual Meeting Abstract June 2013

MicroRNA signature in wound healing following excimer laser ablation: Role of miR-133b on TGF- β, CTGF, collagen and smooth muscle actin synthesis in corneal fibroblast

Paulette Robinson; Tsai-Der Chuang; Sriniwas Sriram; Liya Pi; Xiao Ping Luo; Bryon Petersen; Gregory Schultz

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):5223.

ARVO Annual Meeting Abstract June 2013

Initial Evidence that Immune Cell Infiltrates are Candidate Sources of Post-Surface Ablation Stromal Roughening

Daniel Gibson; Gregory Schultz

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):5231.

Biochemistry and Molecular Biology December 2012

Effect of Connective Tissue Growth Factor on Protein Kinase Expression and Activity in Human Corneal Fibroblasts

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Siva S. Radhakrishnan; Timothy D. Blalock; Paulette M. Robinson; Genevieve Secker; Julie Daniels; Gary R. Grotendorst; Gregory S. Schultz
TAGS: connective tissue growth factor, cornea, fibroblasts, protein kinase, proteins, phosphotransferases
Invest. Ophthalmol. Vis. Sci.. 2012; 53(13):8076-8085. https://doi.org/10.1167/iovs.12-10790

Biochemistry and Molecular Biology December 2012

Proteolytic Processing of Connective Tissue Growth Factor in Normal Ocular Tissues and during Corneal Wound Healing

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Paulette M. Robinson; Tyler S. Smith; Dilan Patel; Meera Dave; Alfred S. Lewin; Liya Pi; Edward W. Scott; Sonal S. Tuli; Gregory S. Schultz
TAGS: connective tissue growth factor, cornea
Invest. Ophthalmol. Vis. Sci.. 2012; 53(13):8093-8103. https://doi.org/10.1167/iovs.12-10419

Cornea November 2012

Ectopic Epithelial Implants following Surface Ablation of the Cornea

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Daniel J. Gibson; Gregory S. Schultz
TAGS: ablation, cornea, epithelium, implants, wound healing, mice
Invest. Ophthalmol. Vis. Sci.. 2012; 53(12):7760-7765. https://doi.org/10.1167/iovs.12-10768

Glaucoma November 2012

Comparison of Single versus Multiple Injections of the Protein Saratin for Prolonging Bleb Survival in a Rabbit Model

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Jeff Min; Zachary L. Lukowski; Monica A. Levine; Craig A. Meyers; Ashley R. Beattie; Gregory S. Schultz; Don A. Samuelson; Mark B. Sherwood
TAGS: blister, injections, oryctolagus cuniculus, proteins
Invest. Ophthalmol. Vis. Sci.. 2012; 53(12):7625-7630. https://doi.org/10.1167/iovs.12-10120

Biochemistry and Molecular Biology June 2012

A Connective Tissue Growth Factor Signaling Receptor in Corneal Fibroblasts

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Timothy D. Blalock; Daniel J. Gibson; Matthew R. Duncan; Sonal S. Tuli; Gary R. Grotendorst; Gregory S. Schultz
TAGS: connective tissue growth factor, fibroblasts
Invest. Ophthalmol. Vis. Sci.. 2012; 53(7):3387-3394. https://doi.org/10.1167/iovs.12-9425

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Assessment of Topical Therapies for Improving the Optical Clarity Following Stromal Wounding in a Novel Ex Vivo Canine Cornea Model

Assessment of topical therapies for improving optical clarity following stromal wounding in a novel ex vivo canine cornea model.

Localized AAV-PEDF gene transfer reduces corneal neovascularization significantly in rabbits in vivo via selective apoptosis

PUT THE PRESERVATIVE IN THE BOTTLE, NOT IN THE EYE!

Development and assessment of a novel ex vivo canine model of corneal epithelial wound healing

CTGF Binds To Growth Factors Of The Cysteine Knot Superfamily And Is Critical For Corneal Wound Healing Through Modulation Of PDGF-B Signaling

Targeted Smad7 gene transfer into stroma attenuates corneal scarring

Tissue-Specific Knockout of Connective Tissue Growth Factor in the Cornea and Lens Epithelia Results in an Aniridia-Like Phenotype

Conditional Knockout of CTGF Affects Corneal Wound Healing

Triple Combination of siRNAs Targeting TGFβ1, TGFβR2, and CTGF Enhances Reduction of Collagen I and Smooth Muscle Actin in Corneal Fibroblasts

MicroRNA Signature in Wound Healing Following Excimer Laser Ablation: Role of miR-133b on TGFβ1, CTGF, SMA, and COL1A1 Expression Levels in Rabbit Corneal Fibroblasts

The Progression of Haze Formation in Rabbit Corneas Following Phototherapeutic Keratectomy

Nanoparticle Vectored siRNAs Reduce Profibrotic Gene Expression in Wounded Rabbit Corneas

MicroRNA signature in wound healing following excimer laser ablation: Role of miR-133b on TGF- β, CTGF, collagen and smooth muscle actin synthesis in corneal fibroblast

Initial Evidence that Immune Cell Infiltrates are Candidate Sources of Post-Surface Ablation Stromal Roughening

Effect of Connective Tissue Growth Factor on Protein Kinase Expression and Activity in Human Corneal Fibroblasts

Proteolytic Processing of Connective Tissue Growth Factor in Normal Ocular Tissues and during Corneal Wound Healing

Ectopic Epithelial Implants following Surface Ablation of the Cornea

Comparison of Single versus Multiple Injections of the Protein Saratin for Prolonging Bleb Survival in a Rabbit Model

A Connective Tissue Growth Factor Signaling Receptor in Corneal Fibroblasts

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