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Letters to the Editor March 2017

Chronic, Systemic Interleukin-18 Does Not Promote Macular Degeneration or Choroidal Neovascularization

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Scott W. Canna; Guangpu Shi; Igal Gery; H. Nida Sen
TAGS: choroidal neovascularization, interleukin-18, macular degeneration
Invest. Ophthalmol. Vis. Sci.. 2017; 58(3):1764-1765. doi: 10.1167/iovs.17-21697

Immunology and Microbiology March 2016

Digoxin Inhibits Induction of Experimental Autoimmune Uveitis in Mice, but Causes Severe Retinal Degeneration

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Samuel J. H. Hinshaw; Osato Ogbeifun; Wambui S. Wandu; Cancan Lyu; Guangpu Shi; Yichao Li; Haohua Qian; Igal Gery
TAGS: digoxin, retinal degeneration, uveitis, mice
Invest. Ophthalmol. Vis. Sci.. 2016; 57(3):1441-1447. doi: 10.1167/iovs.15-19040

ARVO Annual Meeting Abstract June 2015

TMP778 Inhibits Induction of Experimental Autoimmune Uveitis and related immune responses

Samuel Hinshaw; Wambul (Sylvia) Wambul Wandu; Guangpu Shi; Jianfei Yang; Igal Gery

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):851. doi:

ARVO Annual Meeting Abstract June 2015

MICRORNA-155 MEDIATES HUMAN RETINAL PIGMENT EPITHELIUM INFLAMMASOME ACTIVITY

Congxiao Zhang; Arvydas Maminishkis; Guangpu Shi; Sheldon S Miller

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4223. doi:

Retinal Cell Biology March 2015

Inflammasomes Induced by 7-Ketocholesterol and Other Stimuli in RPE and in Bone Marrow–Derived Cells Differ Markedly in Their Production of IL-1β and IL-18

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Guangpu Shi; Siqi Chen; Wambui S. Wandu; Osato Ogbeifun; Lindsey F. Nugent; Arvydas Maminishkis; Samuel J. H. Hinshaw; Ignacio R. Rodriguez; Igal Gery
TAGS: cytokine, interleukin-18, bone marrow, inflammasomes, retinal pigment cell
Invest. Ophthalmol. Vis. Sci.. 2015; 56(3):1658-1664. doi: 10.1167/iovs.14-14557

ARVO Annual Meeting Abstract April 2014

Leucine-rich repeat kinase 2 (LRRK2) deficiency diminishes the development of EAU

Sylvia Wandu; Guangpu Shi; Osato Ogbeifun; Lindsey Nugent; Huaibin Cai; Igal Gery

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1866. doi:

ARVO Annual Meeting Abstract April 2014

Effects of digoxin on experimental autoimmune uveitis (EAU) development and the mouse retina

Samuel JH Hinshaw; Osato Ogbeifun; Guangpu Shi; Igal Gery

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1869. doi:

Immunology and Microbiology November 2013

ITE, A Novel Endogenous Nontoxic Aryl Hydrocarbon Receptor Ligand, Efficiently Suppresses EAU and T-Cell–Mediated Immunity

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Lindsey F. Nugent; Guangpu Shi; Barbara P. Vistica; Osato Ogbeifun; Samuel J. H. Hinshaw; Igal Gery
TAGS: cytokine, immune response, interleukin-10, interleukin-17, ligands, aryl hydrocarbon receptor, antibodies, mice, immune response, cell-mediated, foxp3 gene
Invest. Ophthalmol. Vis. Sci.. 2013; 54(12):7463-7469. doi: 10.1167/iovs.12-11479

ARVO Annual Meeting Abstract June 2013

7-Ketocholesterol Induces Interleukin(IL)-1 beta and IL-18 Production in RPE Cells via Activation of the Inflammasome

Guangpu Shi; Osato Ogbeifun; Lindsey Nugent; Ignacio Rodriguez; Igal Gery

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):150. doi:

ARVO Annual Meeting Abstract March 2012

A Novel Nontoxic Aryl Hydrocarbon Receptor Ligand, ITE, Suppresses Immune-mediated Ocular Inflammation

Lindsey F. Nugent; Guangpu Shi; Barbara P. Vistica; Cuiyan Tan; Igal Gery

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):2759. doi:

ARVO Annual Meeting Abstract March 2012

DAP-12, a Major Immunomediator, Either Promotes or Suppresses EAU Development

Barbara P. Vistica; Vanessa Montalvo-Reddin; Guangpu Shi; Lindsey Nugent; Laura Quigley; Daniel W. McVicar; Igal Gery

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):6239. doi:

ARVO Annual Meeting Abstract March 2012

Cell-cell Interaction with APC, not IL-23, is Required for Naive CD4 Cells to Acquire Pathogenicity During Th17 Lineage Commitment

Guangpu Shi; Jenna D. Lovaas; Cuiyan Tan; Barbara P. Vistica; Eric F. Wawrousek; Mehak K. Aziz; Rachael C. Rigden; Rachel R. Caspi; Igal Gery

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):5487. doi:

ARVO Annual Meeting Abstract April 2011

SLAT/Def6 Knock-Out (KO) Mice Exhibit Profoundly Reduced Capacity to Develop Experimental Autoimmune Uveitis (EAU)

Barbara P. Vistica; Guangpu Shi; Lindsey Nugent; Amnon Altman; Igal Gery

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):2926. doi:

ARVO Annual Meeting Abstract April 2011

Acquisition of Th1, Th17, or Treg Phenotypes Differs Among CD4 T Cells in Ocular Inflammation Triggered by Different TLR Ligands

Guangpu Shi; Barbara P. Vistica; Lindsey F. Nugent; Eric F. Wawrousek; Igal Gery

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):2279. doi:

ARVO Annual Meeting Abstract April 2011

Antigen-Specific Th9 Cells are Unique in their Cytokine Kinetics, Plasticity and Retention at the Inflammatory Site

Lindsey F. Nugent; Cuiyan Tan; Mehak Aziz; Barbara P. Vistica; Guangpu Shi; Igal Gery

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):3011. doi:

Retinal Cell Biology October 2008

Control of Chemokine Gradients by the Retinal Pigment Epithelium

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Guangpu Shi; Arvydas Maminishkis; Tina Banzon; Stephen Jalickee; Rong Li; Jeffrey Hammer; Sheldon S. Miller
TAGS: cytokine, tumor necrosis factors, chemokines, bodily secretions, bathing, retinal pigment epithelium
Invest. Ophthalmol. Vis. Sci.. 2008; 49(10):4620-4630. doi: 10.1167/iovs.08-1816

Retinal Cell Biology August 2006

Confluent Monolayers of Cultured Human Fetal Retinal Pigment Epithelium Exhibit Morphology and Physiology of Native Tissue

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Arvydas Maminishkis; Shan Chen; Stephen Jalickee; Tina Banzon; Guangpu Shi; Fei E. Wang; Todd Ehalt; Jeffrey A. Hammer; Sheldon S. Miller
TAGS: vascular endothelial growth factor a, cell culture techniques, immunohistochemistry, fetus, tissue membrane, body tissue, bathing, physiology, proteins, morphology
Invest. Ophthalmol. Vis. Sci.. 2006; 47(8):3612-3624. doi: 10.1167/iovs.05-1622

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Chronic, Systemic Interleukin-18 Does Not Promote Macular Degeneration or Choroidal Neovascularization

Digoxin Inhibits Induction of Experimental Autoimmune Uveitis in Mice, but Causes Severe Retinal Degeneration

TMP778 Inhibits Induction of Experimental Autoimmune Uveitis and related immune responses

MICRORNA-155 MEDIATES HUMAN RETINAL PIGMENT EPITHELIUM INFLAMMASOME ACTIVITY

Inflammasomes Induced by 7-Ketocholesterol and Other Stimuli in RPE and in Bone Marrow–Derived Cells Differ Markedly in Their Production of IL-1β and IL-18

Leucine-rich repeat kinase 2 (LRRK2) deficiency diminishes the development of EAU

Effects of digoxin on experimental autoimmune uveitis (EAU) development and the mouse retina

ITE, A Novel Endogenous Nontoxic Aryl Hydrocarbon Receptor Ligand, Efficiently Suppresses EAU and T-Cell–Mediated Immunity

7-Ketocholesterol Induces Interleukin(IL)-1 beta and IL-18 Production in RPE Cells via Activation of the Inflammasome

A Novel Nontoxic Aryl Hydrocarbon Receptor Ligand, ITE, Suppresses Immune-mediated Ocular Inflammation

DAP-12, a Major Immunomediator, Either Promotes or Suppresses EAU Development

Cell-cell Interaction with APC, not IL-23, is Required for Naive CD4 Cells to Acquire Pathogenicity During Th17 Lineage Commitment

SLAT/Def6 Knock-Out (KO) Mice Exhibit Profoundly Reduced Capacity to Develop Experimental Autoimmune Uveitis (EAU)

Acquisition of Th1, Th17, or Treg Phenotypes Differs Among CD4 T Cells in Ocular Inflammation Triggered by Different TLR Ligands

Antigen-Specific Th9 Cells are Unique in their Cytokine Kinetics, Plasticity and Retention at the Inflammatory Site

Control of Chemokine Gradients by the Retinal Pigment Epithelium

Confluent Monolayers of Cultured Human Fetal Retinal Pigment Epithelium Exhibit Morphology and Physiology of Native Tissue

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