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Retina May 2025

Clofarabine Enhances the Transduction Efficiency of Recombinant AAV2 in the Retina

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Yuyao Diao; Xuewei Xiong; Jiayan Liu; Xingbo Teng; Qi Shi; Shangli Jin; Yahui Lei; Shisi Ma; Guei-Sheung Liu; Lian Liu; Guocheng Yu; Jiang-Hui Wang; Jingxiang Zhong; Leilei Tu
TAGS: clofarabine, retina
Invest. Ophthalmol. Vis. Sci.. 2025; 66(5):42. https://doi.org/10.1167/iovs.66.5.42

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Inhibitory Effects of 5Z-7-Oxozeaenol on TGFβ1-Induced Responses in Human Tenon’s Fibroblasts

Jennifer Fan Gaskin; Cheng Zeng; Roy Kong; Guei-Sheung Liu; Elsa Chan

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5148.

ARVO Annual Meeting Abstract June 2024

Harnessing CRISPR-Cas RNA base editing to treat inherited retinal disease

Guei-Sheung Liu; Satheesh Kumar; Yi-Wen Hsiao; Lewis Fry

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6053.

ARVO Annual Meeting Abstract June 2023

CRISPR-Cas13e knockdown of VEGFA mRNA for treatment of ocular neovascularisation

Satheesh Kumar; Jiang-Hui Wang; Da Zhao; Bang Bui; Guei-Sheung Liu

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3789.

Genetics April 2023

Retinal Aging Transcriptome and Cellular Landscape in Association With the Progression of Age-Related Macular Degeneration

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Jiang-Hui Wang; Raymond C. B. Wong; Guei-Sheung Liu
TAGS: age-related macular degeneration, aging, genes, retina, neural retina
Invest. Ophthalmol. Vis. Sci.. 2023; 64(4):32. https://doi.org/10.1167/iovs.64.4.32

Includes: Supplemental Content

Retina August 2022

Retinal Transcriptome and Cellular Landscape in Relation to the Progression of Diabetic Retinopathy

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Jiang-Hui Wang; Raymond C. B. Wong; Guei-Sheung Liu
TAGS: diabetic retinopathy, genes, gender, cyclin d1, gene expression, donors
Invest. Ophthalmol. Vis. Sci.. 2022; 63(9):26. https://doi.org/10.1167/iovs.63.9.26

Includes: Supplemental Content

Retina November 2021

Bulk Gene Expression Deconvolution Reveals Infiltration of M2 Macrophages in Retinal Neovascularization

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Jiang-Hui Wang; Satheesh Kumar; Guei-Sheung Liu
TAGS: gene expression, genes, macrophages, rats, retinal neovascularization, immune response, proteins, infiltrates, rna-seq
Invest. Ophthalmol. Vis. Sci.. 2021; 62(14):22. https://doi.org/10.1167/iovs.62.14.22

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

MicroRNA-143 plays a protective role in ischemia-induced retinal neovascularization

Guei-Sheung Liu; Jiang-Hui Wang; Jinying Chen; Leilei Tu; Vikrant Singh; Moeen Riaz; Fan Li; Alex W Hewitt; Peter van Wijngaarden; Gregory J. Dusting

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3261.

ARVO Annual Meeting Abstract July 2019

CRISPR/Cas-mediated base editing of the AMD high-risk Y402H complement factor H variant

Alex W Hewitt; Peter Tran; Mohd Khairul Nizam Mohd Khalid; Alice Pébay; Anthony L Cook; Helena Liang; Raymond Wong; Jamie E Craig; Guei-Sheung Liu; Sandy Hung

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4947.

ARVO Annual Meeting Abstract July 2019

Comparison of CRISPR/Cas endonuclease gene editing efficiency of retinal cells in vivo

Fan Li; Kristof Wing; Jiang-Hui Wang; James Bender; Chi D Luu; Jinying Chen; Vivienne Lu; Qi Wang; Qinyi Lu; Peter Tran; Kaylene Young; Anna King; Sandy Hung; Guei-Sheung Liu; Alex W Hewitt

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4226.

ARVO Annual Meeting Abstract July 2018

Using cell reprogramming technology to convert Müller glia into photoreceptors

Raymond Ching Bong Wong; Tu Nguyen; Lucy Lyujie Fang; Camden Lo; Jafar Jabbari; Sandy Hung; Rick Guei-Sheung Liu; Chi D Luu; Mark C Gillies; Alex Hewitt

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4578.

ARVO Annual Meeting Abstract June 2017

Transforming Growth Factor beta-Activated Kinase 1 (TAK1) is a novel target for retinal neovascularization

Jiang-Hui Wang; Damien Ling; Leilei Tu; Moeen Riaz; Peter Van Wijngaarden; Gregory Dusting; Guei-sheung Liu

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5792.

ARVO Annual Meeting Abstract June 2017

Gene delivery of vasostatin via a self-complementary adeno-associated virus 2 inhibits retinal neovascularization in a rat model of oxygen-induced retinopathy

Leilei Tu; Jiang-Hui Wang; Ming-Hong Tai; Gregory Dusting; Guei-Sheung Liu

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3443.

Biochemistry and Molecular Biology June 2017

Transforming Growth Factor β1–Induced NADPH Oxidase-4 Expression and Fibrotic Response in Conjunctival Fibroblasts

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Karl David Brown; Manisha H. Shah; Guei-Sheung Liu; Elsa C. Chan; Jonathan G. Crowston; Hitesh M. Peshavariya
TAGS: conjunctiva, fibroblasts, hydrogen peroxide, transforming growth factors, nadp, oxidase, curcumin, collagen synthesis, protein isoforms, collagen
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):3011-3017. https://doi.org/10.1167/iovs.16-20633

Includes: Supplemental Content

ARVO Annual Meeting Abstract September 2016

Investigating the laser model of experimental choroidal neovascularization in Long Evans rats

Selwyn Marc Prea; Guei-Sheung Liu; Gregory James Dusting; Algis J Vingrys; Bang V Bui

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2139.

ARVO Annual Meeting Abstract September 2016

Utility of Commercially Available Cationic Lipid-based Delivery of CRISPR-Cas9 to the Retina in vivo

Sandy Shen-Chi Hung; Vicki Chrysostomou; Hsin-Hui Shen; Fan li; Anna E King; Jonathan G Crowston; Alice Pébay; Bang V Bui; Guei-Sheung Liu; Alex W Hewitt

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4038.

Genetics June 2016

AAV-Mediated CRISPR/Cas Gene Editing of Retinal Cells In Vivo

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Sandy S. C. Hung; Vicki Chrysostomou; Fan Li; Jeremiah K. H. Lim; Jiang-Hui Wang; Joseph E. Powell; Leilei Tu; Maciej Daniszewski; Camden Lo; Raymond C. Wong; Jonathan G. Crowston; Alice Pébay; Anna E. King; Bang V. Bui; Guei-Sheung Liu; Alex W. Hewitt
TAGS: crispr, genes, retina, mice, eye, electroretinography
Invest. Ophthalmol. Vis. Sci.. 2016; 57(7):3470-3476. https://doi.org/10.1167/iovs.16-19316

ARVO Annual Meeting Abstract April 2014

NADPH Oxidase Signaling Crucial for Neovascularization in Oxygen-induced Retinopathy in Mice: Nox2, Nox4 and VEGF Signaling

Gregory J Dusting; Hitesh Peshavariya; Elsa Chan; Peter van Wijngaarden; Guei-Sheung Liu

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1265.

Retina October 2013

Involvement of Nox2 NADPH Oxidase in Retinal Neovascularization

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Elsa C. Chan; Peter van Wijngaarden; Guei-Sheung Liu; Fan Jiang; Hitesh Peshavariya; Gregory J. Dusting
TAGS: cybb gene, mice, retinal neovascularization, nadph oxidases, neovascularization, pathologic, retina, superoxides, vascular endothelial growth factor a, hypoxia
Invest. Ophthalmol. Vis. Sci.. 2013; 54(10):7061-7067. https://doi.org/10.1167/iovs.13-12883

Includes: Supplemental Content

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Clofarabine Enhances the Transduction Efficiency of Recombinant AAV2 in the Retina

Inhibitory Effects of 5Z-7-Oxozeaenol on TGFβ1-Induced Responses in Human Tenon’s Fibroblasts

Harnessing CRISPR-Cas RNA base editing to treat inherited retinal disease

CRISPR-Cas13e knockdown of VEGFA mRNA for treatment of ocular neovascularisation

Retinal Aging Transcriptome and Cellular Landscape in Association With the Progression of Age-Related Macular Degeneration

Retinal Transcriptome and Cellular Landscape in Relation to the Progression of Diabetic Retinopathy

Bulk Gene Expression Deconvolution Reveals Infiltration of M2 Macrophages in Retinal Neovascularization

MicroRNA-143 plays a protective role in ischemia-induced retinal neovascularization

CRISPR/Cas-mediated base editing of the AMD high-risk Y402H complement factor H variant

Comparison of CRISPR/Cas endonuclease gene editing efficiency of retinal cells in vivo

Using cell reprogramming technology to convert Müller glia into photoreceptors

Transforming Growth Factor beta-Activated Kinase 1 (TAK1) is a novel target for retinal neovascularization

Gene delivery of vasostatin via a self-complementary adeno-associated virus 2 inhibits retinal neovascularization in a rat model of oxygen-induced retinopathy

Transforming Growth Factor β1–Induced NADPH Oxidase-4 Expression and Fibrotic Response in Conjunctival Fibroblasts

Investigating the laser model of experimental choroidal neovascularization in Long Evans rats

Utility of Commercially Available Cationic Lipid-based Delivery of CRISPR-Cas9 to the Retina in vivo

AAV-Mediated CRISPR/Cas Gene Editing of Retinal Cells In Vivo

NADPH Oxidase Signaling Crucial for Neovascularization in Oxygen-induced Retinopathy in Mice: Nox2, Nox4 and VEGF Signaling

Involvement of Nox2 NADPH Oxidase in Retinal Neovascularization

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