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Genetics December 2020

Candidate Genetic Modifiers for RPGR Retinal Degeneration

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Tatyana Appelbaum; Leonardo Murgiano; Doreen Becker; Evelyn Santana; Gustavo D. Aguirre

Invest. Ophthalmol. Vis. Sci.. 2020; 61(14):20. doi: https://doi.org/10.1167/iovs.61.14.20

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Characterization of a Novel Prolactin Transcript in Photoreceptors of Degenerating Retina

Raghavi Sudharsan; Leonardo Murgiano; Gustavo D Aguirre; William A Beltran

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):666. doi:

ARVO Annual Meeting Abstract June 2020

Subretinal transplantation and survival of hESC-derived photoreceptor precursor cells in normal canine eyes

Ana Ripolles Garcia; Valerie Dufour; Joe Phillips; Natalia Dolgova; Allison Ludwig; Sara Stuedemann; Svetlana Savina; John H Wolfe; Karina E Guziewicz; Oliver Garden; David M Gamm; Gustavo D Aguirre; William A Beltran

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):796. doi:

ARVO Annual Meeting Abstract June 2020

Decrease in the level of axon guidance receptor ROBO1 in rod synaptic terminals is followed by axonal retraction.

Tatyana Appelbaum; Evelyn Santana; Gustavo D Aguirre

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1285. doi:

ARVO Annual Meeting Abstract June 2020

A naturally-occurring canine model of congenital microphthalmia with multisystemic features

Esha Banerjee; Margret L. Casal; Cynthia O'Connor; Keiko Miyadera; Brian Thomas Kedrick; Petra Werner; Leonardo Murgiano; Gustavo D Aguirre; Karina E Guziewicz

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2229. doi:

ARVO Annual Meeting Abstract June 2020

AAV gene therapy restores ON-bipolar cell function in a canine model of LRIT3 -congenital stationary night blindness

Keiko Miyadera; Karolina Roszak; Ana Ripolles Garcia; Evelyn Santana; Sommer M Iffrig; Meike Visel; Leah Byrne; William A Beltran; John Gerard Flannery; Gustavo D Aguirre

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2298. doi:

ARVO Annual Meeting Abstract June 2020

A newly recognized canine phenotype of early-onset retinal degeneration

Karina E Guziewicz; Valerie Dufour; Lauren Lew; Brian Thomas Kendrick; Ana Ripolles Garcia; William A Beltran; Artur V Cideciyan; Samuel G Jacobson; Gustavo D Aguirre

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2792. doi:

ARVO Annual Meeting Abstract June 2020

Azobenzene-based BENAQ photoswitch confers light-sensitivity to degenerating and WT canine retinas.

Sergei Nikonov; Roman Nikonov; Natalia Dolgova; Richard H Kramer; Russell Van Gelder; Gustavo D Aguirre; William A Beltran

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4285. doi:

ARVO Annual Meeting Abstract June 2020

AAV capsid variants target canine and primate bipolar cells after subretinal and intravitreal delivery

William A Beltran; Natalia Dolgova; Valerie L Dufour; Iwabe Simone; Ryan F. Boyd; Joshua T Bartoe; Gustavo D Aguirre; David L schaffer; John Gerard Flannery; Leah Byrne

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4489. doi:

ARVO Annual Meeting Abstract June 2020

Differential expression of protein tyrosine phosphatases in canine models of retinal degeneration

Catharina Grubaugh; Leonardo Murgiano; Raghavi Sudharsan; Brian Thomas Kedrick; William A Beltran; Karina E Guziewicz; Gustavo D Aguirre

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5004. doi:

Retinal Cell Biology March 2020

Critical Decrease in the Level of Axon Guidance Receptor ROBO1 in Rod Synaptic Terminals Is Followed by Axon Retraction

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Tatyana Appelbaum; Evelyn Santana; Gustavo D. Aguirre
TAGS: axon, axon guidance, dog, domestic, presynaptic terminals, retina, rod photoreceptors, proteins
Invest. Ophthalmol. Vis. Sci.. 2020; 61(3):11. doi: https://doi.org/10.1167/iovs.61.3.11

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Structural PPT1 variant implicated in non–syndromic retinal degeneration in dogs

Leonardo Murgiano; Doreen Becker; Dina Torjman; Jessica K Niggel; Vidhya Jagannathan; Sue Pearce-Kelling; Martin L Katz; Gustavo D Aguirre

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2932. doi:

ARVO Annual Meeting Abstract July 2019

Safety and long-term efficacy of AAV2- BEST1 gene augmentation therapy in canine model of Best vitelliform macular dystrophies

Karina E Guziewicz; Artur V Cideciyan; Brian T. Kendrick; Valerie L Dufour; Gordon Ruthel; Andras M Komaromy; Simone Iwabe; William Hauswirth; William A Beltran; Samuel G Jacobson; Gustavo D Aguirre

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5200. doi:

ARVO Annual Meeting Abstract July 2019

Long-term longitudinal assessment of functional rescue in mutant XLRP dogs after RPGR gene augmentation therapy

William A Beltran; Valerie L Dufour; Sommer M Ainsworth; Karolina Roszak; Gustavo D Aguirre

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4031. doi:

ARVO Annual Meeting Abstract July 2019

Prolactin Expression is Induced in Photoreceptors of Degenerating Retina

Raghavi Sudharsan; Leonardo Murgiano; Gustavo D Aguirre; William A Beltran

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5991. doi:

ARVO Annual Meeting Abstract July 2019

Implications of the MAP9 mutation as a modifier of canine RPGRIP1 cone-rod dystrophy

Courtney Spector; Raghavi Sudharsan; Karolina Roszak; Gustavo D Aguirre; Keiko Miyadera

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2349. doi:

ARVO Annual Meeting Abstract July 2019

The sequence variants in the novel lncRNAs, ROBO1-AS and ROBO2-AS , correlate with phenotype severity in canine RPGR-XLPRA1

Tatyana Appelbaum; Leonardo Murgiano; Doreen Becker; Evelyn Santana; Gustavo D Aguirre

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3436. doi:

Lecture April 2019

Introducing Artur V. Cideciyan and Samuel G. Jacobson, the 2018 Recipients of the Proctor Medal

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Elise Héon; Gustavo D. Aguirre
TAGS: animal model, blindness, eye, gene therapy, genes, genetics, mutation, photoreceptors, retina, retinal degeneration
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1677-1679. doi: https://doi.org/10.1167/iovs.19-26884

New Developments in Vision Research September 2018

Translational Retinal Research and Therapies

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Alison J. Hardcastle; Paul A. Sieving; José-Alain Sahel; Samuel G. Jacobson; Artur V. Cideciyan; John G. Flannery; William A. Beltran; Gustavo D. Aguirre
TAGS: gene therapy, genes, mutation, optogenetics, photoreceptors, proteins, retina, retinal cone, retinitis pigmentosa, rhodopsin
Trans. Vis. Sci. Tech.. 2018; 7(5):8. doi: https://doi.org/10.1167/tvst.7.5.8

ARVO Annual Meeting Abstract July 2018

Association of long-term RPE65 expression and photoreceptor preservation in RPE65 -gene therapy-treated canines

Kristin Lee Gardiner; William A Beltran; Gustavo D Aguirre

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5318. doi:

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Candidate Genetic Modifiers for RPGR Retinal Degeneration

Characterization of a Novel Prolactin Transcript in Photoreceptors of Degenerating Retina

Subretinal transplantation and survival of hESC-derived photoreceptor precursor cells in normal canine eyes

Decrease in the level of axon guidance receptor ROBO1 in rod synaptic terminals is followed by axonal retraction.

A naturally-occurring canine model of congenital microphthalmia with multisystemic features

AAV gene therapy restores ON-bipolar cell function in a canine model of LRIT3 -congenital stationary night blindness

A newly recognized canine phenotype of early-onset retinal degeneration

Azobenzene-based BENAQ photoswitch confers light-sensitivity to degenerating and WT canine retinas.

AAV capsid variants target canine and primate bipolar cells after subretinal and intravitreal delivery

Differential expression of protein tyrosine phosphatases in canine models of retinal degeneration

Critical Decrease in the Level of Axon Guidance Receptor ROBO1 in Rod Synaptic Terminals Is Followed by Axon Retraction

Structural PPT1 variant implicated in non–syndromic retinal degeneration in dogs

Safety and long-term efficacy of AAV2- BEST1 gene augmentation therapy in canine model of Best vitelliform macular dystrophies

Long-term longitudinal assessment of functional rescue in mutant XLRP dogs after RPGR gene augmentation therapy

Prolactin Expression is Induced in Photoreceptors of Degenerating Retina

Implications of the MAP9 mutation as a modifier of canine RPGRIP1 cone-rod dystrophy

The sequence variants in the novel lncRNAs, ROBO1-AS and ROBO2-AS , correlate with phenotype severity in canine RPGR-XLPRA1

Introducing Artur V. Cideciyan and Samuel G. Jacobson, the 2018 Recipients of the Proctor Medal

Translational Retinal Research and Therapies

Association of long-term RPE65 expression and photoreceptor preservation in RPE65 -gene therapy-treated canines

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