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Article May 2025

Eye-movement patterns for perceiving bistable figures

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Yi-Hsuan Hsu; Chien-Chung Chen
TAGS: ducks, eye movement, oryctolagus cuniculus, perception, eye fixation, eye
Journal of Vision. 2025; 25(6):3. https://doi.org/10.1167/jov.25.6.3

Glaucoma May 2025

Aqueous Humor Antioxidants in Glaucoma: Correlations With Subtypes, Intraocular Pressure, and Medication Use—A Prospective Study

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Yu-Ting Tsao; Hung-Chi Chen; Yi-Jen Hsueh; Yu-Chun Cheng; Eugene Yu-Chuan Kang; Chu-Yen Huang; Yung-Sung Lee
TAGS: antioxidants, aqueous humor, glaucoma, intraocular pressure, teller acuity cards, total arterial compliance, trigeminal autonomic cephalalgias, prospective studies, drug usage
Trans. Vis. Sci. Tech.. 2025; 14(5):7. https://doi.org/10.1167/tvst.14.5.7

Includes: Supplemental Content

Cornea April 2025

Prox1 Protein in Corneal Limbal Lymphatic Vessels Maintains Limbal Stem Cell Stemness and Regulates Corneal Injury Repair

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An Wang; Zongyuan Li; Yilin Jiang; Mingxiong Chen; Hanrui Yu; Zhao Li; Shengshu Sun; Ge Bai; Qun Wang; Yifei Huang; Liqiang Wang
TAGS: alkalies, burns, cornea, corneal injuries, limbal stem cells, lymphatic vessels, prospero-related homeobox 1 protein, recovery of function, epithelium, rna, messenger
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):81. https://doi.org/10.1167/iovs.66.4.81

Includes: Supplemental Content

Retina April 2025

The Exponential Constriction Model of the Ellipsoid Zone in Taiwanese Individuals With RPGR-Related X-Linked Retinitis Pigmentosa

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Yi-Han Huang; Yu-Shu Huang; Chien-Yu Lin; Ying-Ju Lai; Chang-Hao Yang; Tzzy-Chang Ho; Yi-Ting Hsieh; Po-Ting Yeh; Tso-Ting Lai; Chao-Wen Lin; Chung-May Yang; Pei-Lung Chen; Ta-Ching Chen
TAGS: constriction procedure, disease progression, retinitis pigmentosa, taiwanese, x-linked inheritance, eye, phenotype, exons
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):59. https://doi.org/10.1167/iovs.66.4.59

Includes: Supplemental Content

Cornea April 2025

Proliferator–Activated Receptor Alpha Inhibits Abnormal Extracellular Matrix Accumulation and Maintains Energy Metabolism in Late-Onset Fuchs Endothelial Corneal Dystrophy

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Xiaoqi Li; Anqi Liu; Yannan Zhou; Haolan Qi; Junyi Wang; Mingxiong Chen; Tunan Sun; Jie Wu; Yifei Huang; Liqiang Wang
TAGS: cornea, endothelium, mice, ppar alpha, chronic exertional compartment syndrome, fenofibrate, hereditary corneal dystrophy
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):36. https://doi.org/10.1167/iovs.66.4.36

Includes: Supplemental Content

Genetics March 2025

Corneal Biomechanics Are Associated With FBN1 Mutations in Patients With Marfan Syndrome and Ectopia Lentis

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Qiu-Yi Huo; Rui-Zheng Zhang; Wan-Nan Jia; Ya-Lei Wang; Xin Shen; Xin-Yao Chen; Tian-Hui Chen; Yan Liu; Ling-Hao Song; Xinyue Wang; Yong Lv; Ze-Xu Chen; Yong-Xiang Jiang
TAGS: biomechanics, cornea, ectopia lentis, fibrillin-1, marfan syndrome, mutation, genotype
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):23. https://doi.org/10.1167/iovs.66.3.23

Includes: Supplemental Content

Immunology and Microbiology February 2025

The Signature of Serum Modified Nucleosides in Uveitis

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Haoze Zhou; Yiqiu Hu; Guangming Qin; Jinfeng Kong; Xiujuan Hong; Cheng Guo; Jian Zou; Lei Feng
TAGS: nucleosides, uveitis, rna
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):68. https://doi.org/10.1167/iovs.66.2.68

Includes: Supplemental Content

Clinical and Epidemiologic Research February 2025

Elevated Very-Long-Chain Ceramides in the Vitreous Humor of Patients With Proliferative Diabetic Retinopathy

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Ying-Yi Chen; Chung-May Yang; Chang-Hao Yang; Tzyy-Chang Ho; Yi-Ting Hsieh; Tso-Ting Lai; Tzu-Hsun Tsai; Shu-Yi Huang
TAGS: ceramides, vitreous body, diabetic retinopathy, proliferative diabetic retinopathy
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):28. https://doi.org/10.1167/iovs.66.2.28

Article February 2025

Metrics of two-dimensional smooth pursuit are diverse across participants and stable across days

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Yao Yan; Yilin Wu; Hoi Ming Ken Yip; Nicholas Seow Chiang Price
TAGS: biological markers, pursuit, smooth, reliability, saccades, eye, motion
Journal of Vision. 2025; 25(2):5. https://doi.org/10.1167/jov.25.2.5

Retinal Cell Biology January 2025

Inhibition of Retinal Neovascularization by BEZ235: Targeting the Akt/4EBP1/Cyclin D1 Pathway in Endothelial Cells

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Qi Liu; Ling-Xiao Xia; Wan-Zhao Yi; Ya-Ni Wu; Shuo-Shuo Gu; Jian-Ying Chen; Ting-Ting Liu; Ying-Hui Lu; Yu-Hong Cui; Jing Meng; Hong-Wei Pan
TAGS: cyclin d1, endothelial cells, proto-oncogene proteins c-akt, retinal neovascularization, cell cycle, mice
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):66. https://doi.org/10.1167/iovs.66.1.66

Includes: Supplemental Content

Glaucoma January 2025

SIRT4 Protects Retina Against Excitotoxic Injury by Promoting OPA1-Mediated Müller Glial Cell Mitochondrial Fusion and GLAST Expression

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Qian Ying; Hongdou Luo; Zhi Xie; Yi Huang; Haijian Hu; Ming Jin; Ke Xu; Yulian Pang; Yuning Song; Xu Zhang
TAGS: glutamate, glutamates, mitochondria, neuroglia, optic atrophy, autosomal dominant, proteins, retina, wounds and injuries, n-methylaspartate, retinal injuries
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):62. https://doi.org/10.1167/iovs.66.1.62

Cornea January 2025

Recombinant Thrombomodulin Domain 1 Modulates Macrophage Polarization and Enhances Healing in Corneal Alkali Burns

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Chun-Hsiang Chang; I-Chen Peng; Yi-Hsun Huang
TAGS: alkalies, burns, cornea, macrophage activation, thrombomodulin, wound healing
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):21. https://doi.org/10.1167/iovs.66.1.21

Retina December 2024

Retinal Neurovascular Impairment in Full-Course Diabetic Retinopathy: The Guangdong Diabetic Retinopathy Multiple-Omics Study

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Chunran Lai; Ting Su; Jiahui Cao; Qinyi Li; Zijing Du; Yaxin Wang; Shan Wang; Qiaowei Wu; Yijun Hu; Ying Fang; Huiyi Liao; Zhuoting Zhu; Xianwen Shang; Mingguang He; Honghua Yu; Xiayin Zhang
TAGS: diabetes mellitus, type 2, diabetic retinopathy, electroretinography, nonproliferative diabetic retinopathy, peripheral neurovascular compromise, photopsia, retinal cone, optical coherence tomography, retina, photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):20. https://doi.org/10.1167/iovs.65.14.20

Includes: Supplemental Content

Lens November 2024

In Utero/Childhood/ Adolescence Exposure to Tobacco Smoke and Elderly-Onset Cataract: A Large Prospective Cohort Study

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Chunran Lai; Yaxin Wang; Xiaomin Zeng; Zijing Du; Shan Wang; Zhanjie Lin; Yijun Hu; Ying Fang; Xiayin Zhang; Honghua Yu
TAGS: cataract, smoke, tobacco, adolescent, child, prospective studies, older adult
Trans. Vis. Sci. Tech.. 2024; 13(11):21. https://doi.org/10.1167/tvst.13.11.21

Includes: Supplemental Content

Glaucoma November 2024

Proposing a Methodology for Axon-Centric Analysis of IOP-Induced Mechanical Insult

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Manik Bansal; Bingrui Wang; Susannah Waxman; Fuqiang Zhong; Yi Hua; Yuankai Lu; Juan Reynaud; Brad Fortune; Ian A. Sigal
TAGS: axon, body tissue, intraocular pressure, optic disk, volume, reconstructive surgical procedures
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):1. https://doi.org/10.1167/iovs.65.13.1

Includes: Supplemental Content

Retina October 2024

Automated Posterior Scleral Topography Assessment for Enhanced Staphyloma Visualization and Quantification With Improved Maculopathy Correlation

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Ying Xiang Han; Xiao Xiao Guo; Ya Xing Wang; Jost B. Jonas; Xi Chen; Xiao Fei Wang
TAGS: sclera, staphyloma, macular disorders, eye, magnetic resonance imaging
Trans. Vis. Sci. Tech.. 2024; 13(10):41. https://doi.org/10.1167/tvst.13.10.41

Includes: Supplemental Content

Cornea October 2024

PAX6–WNK2 Axis Governs Corneal Epithelial Homeostasis

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Liqiong Zhu; Chaoqun Chen; Siqi Wu; Huizhen Guo; Lingyu Li; Li Wang; Dongmei Liu; Yu Zhan; Xinyue Du; Jiafeng Liu; Jieying Tan; Ying Huang; Kunlun Mo; Xihong Lan; Hong Ouyang; Jin Yuan; Xiangjun Chen; Jianping Ji
TAGS: cornea, homeostasis, pax6 transcription factor, scirrhous adenocarcinoma, epithelium, chronic exertional compartment syndrome, genes
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):40. https://doi.org/10.1167/iovs.65.12.40

Includes: Supplemental Content

Glaucoma October 2024

Characteristics of a Large Database of Healthy Eyes From Optometry Practices: Implications for a Real-World Reference Database

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Donald C. Hood; Mary Durbin; Sol La Bruna; Chris Lee; Yi Sing Hsiao; Nevin W. El-Nimri; Carlos Gustavo De Moraes; Emmanouil Tsamis
TAGS: eye, optometry, screening, reading (activity)
Trans. Vis. Sci. Tech.. 2024; 13(10):8. https://doi.org/10.1167/tvst.13.10.8

Includes: Supplemental Content

Vision Sciences Society Annual Meeting Abstract September 2024

Test on the effectiveness of virtual nose in reducing cybersickness

Sai Ho Yip; Adrian K. T. Ng; Henry Y. K. Lau; Jeffrey A. Saunders

Journal of Vision. 2024; 24(10):774. https://doi.org/10.1167/jov.24.10.774

Vision Sciences Society Annual Meeting Abstract September 2024

Evidence for efficient inverse graphics in the human brain using large-scale ECoG data

Daniel Calbick; Hakan Yilmaz; Greg McCarthy; Ilker Yildirim

Journal of Vision. 2024; 24(10):1502. https://doi.org/10.1167/jov.24.10.1502

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Eye-movement patterns for perceiving bistable figures

Aqueous Humor Antioxidants in Glaucoma: Correlations With Subtypes, Intraocular Pressure, and Medication Use—A Prospective Study

Prox1 Protein in Corneal Limbal Lymphatic Vessels Maintains Limbal Stem Cell Stemness and Regulates Corneal Injury Repair

The Exponential Constriction Model of the Ellipsoid Zone in Taiwanese Individuals With RPGR-Related X-Linked Retinitis Pigmentosa

Proliferator–Activated Receptor Alpha Inhibits Abnormal Extracellular Matrix Accumulation and Maintains Energy Metabolism in Late-Onset Fuchs Endothelial Corneal Dystrophy

Corneal Biomechanics Are Associated With FBN1 Mutations in Patients With Marfan Syndrome and Ectopia Lentis

The Signature of Serum Modified Nucleosides in Uveitis

Elevated Very-Long-Chain Ceramides in the Vitreous Humor of Patients With Proliferative Diabetic Retinopathy

Metrics of two-dimensional smooth pursuit are diverse across participants and stable across days

Inhibition of Retinal Neovascularization by BEZ235: Targeting the Akt/4EBP1/Cyclin D1 Pathway in Endothelial Cells

SIRT4 Protects Retina Against Excitotoxic Injury by Promoting OPA1-Mediated Müller Glial Cell Mitochondrial Fusion and GLAST Expression

Recombinant Thrombomodulin Domain 1 Modulates Macrophage Polarization and Enhances Healing in Corneal Alkali Burns

Retinal Neurovascular Impairment in Full-Course Diabetic Retinopathy: The Guangdong Diabetic Retinopathy Multiple-Omics Study

In Utero/Childhood/ Adolescence Exposure to Tobacco Smoke and Elderly-Onset Cataract: A Large Prospective Cohort Study

Proposing a Methodology for Axon-Centric Analysis of IOP-Induced Mechanical Insult

Automated Posterior Scleral Topography Assessment for Enhanced Staphyloma Visualization and Quantification With Improved Maculopathy Correlation

PAX6–WNK2 Axis Governs Corneal Epithelial Homeostasis

Characteristics of a Large Database of Healthy Eyes From Optometry Practices: Implications for a Real-World Reference Database

Test on the effectiveness of virtual nose in reducing cybersickness

Evidence for efficient inverse graphics in the human brain using large-scale ECoG data

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