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Genetics November 2023

Association of APOE Haplotypes With Common Age-Related Ocular Diseases in 412,171 Individuals

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Perttu J. Liuska; Joel T. Rämö; Susanna Lemmelä; Kai Kaarniranta; Hannu Uusitalo; Elisa Lahtela; Mark J. Daly; Mika Harju; Aarno Palotie; Joni A. Turunen; for the FinnGen Study†
TAGS: apolipoprotein e, eye diseases, glaucoma, haplotypes, apolipoprotein e genotype, alleles, genotype
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):33. https://doi.org/10.1167/iovs.64.14.33

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

Biological processes and clinical variables affecting trabeculectomy surgery outcome

Janika Nättinen; Ulla Aapola; Fabian Gielen; Anu Vaajanen; Hannu Uusitalo

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3681 – A0366.

ARVO Annual Meeting Abstract June 2021

Ocular surface characteristics in Finnish elderly population

Janika Nättinen; Ulla Aapola; Jaakko Tuomilehto; Sirkka Keinänen-Kiukaanniemi; Jouko Saramies; Hannu Uusitalo

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1263.

Articles February 2020

Comparison of Capillary and Schirmer Strip Tear Fluid Sampling Methods Using SWATH-MS Proteomics Approach

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Janika Nättinen; Ulla Aapola; Antti Jylhä; Anu Vaajanen; Hannu Uusitalo
TAGS: blood capillaries, datasets, libraries, proteins, proteomics, sampling method
Trans. Vis. Sci. Tech.. 2020; 9(3):16. https://doi.org/10.1167/tvst.9.3.16

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Age effects on tear film proteomics

Janika Nättinen; Antti Jylhä; Ulla Aapola; Petri Mäkinen; Roger W Beuerman; Juhani Pietilä; Anu Vaajanen; Hannu Uusitalo

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5681.

Retina May 2019

Viability of Mouse Retinal Explant Cultures Assessed by Preservation of Functionality and Morphology

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Virpi Alarautalahti; Symantas Ragauskas; Jenni J. Hakkarainen; Hannele Uusitalo-Järvinen; Hannu Uusitalo; Jari Hyttinen; Giedrius Kalesnykas; Soile Nymark
TAGS: language morphology, mice, morphology, retina, tissue preparation, photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2019; 60(6):1914-1927. https://doi.org/10.1167/iovs.18-25156

ARVO Annual Meeting Abstract July 2018

Proteomic analysis of Oxygen Induced Retinopathy Model using SWATH -MS proteomics reveals novel potential therapeutic target molecules

Hannele Uusitalo-Jarvinen; Maria Vähätupa; Janika Nättinen; Antti Jylha; Marko Kataja; Ulla Aapola; Tero Jarvinen; Hannu M T Uusitalo

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5477.

Retina July 2018

SWATH-MS Proteomic Analysis of Oxygen-Induced Retinopathy Reveals Novel Potential Therapeutic Targets

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Maria Vähätupa; Janika Nättinen; Antti Jylhä; Ulla Aapola; Marko Kataja; Peeter Kööbi; Tero A. H. Järvinen; Hannu Uusitalo; Hannele Uusitalo-Järvinen
TAGS: angiogenesis, hypoxia, oxygen, proteins, proteomics, retina, retinal diseases, myh9 gene
Invest. Ophthalmol. Vis. Sci.. 2018; 59(8):3294-3306. https://doi.org/10.1167/iovs.18-23831

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

Visual acuity, health-related quality of life, and their correlation in a nationwide epidemiological study of adult population in Finland

Alexandra Mikhailova; Matti Ojamo; Mika Gissler; Seppo Koskinen; Harri Rissanen; Päivi Sainio; Hannu M T Uusitalo

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1354.

ARVO Annual Meeting Abstract June 2017

Tear proteome provides basis for patient stratification after switching to a unpreserved glaucoma medication

Antti Jylhä; Janika Nattinen; Ulla Aapola; Matti Nykter; Roger W. Beuerman; Hannu M T Uusitalo

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2115.

ARVO Annual Meeting Abstract June 2017

Tear film proteomics after LASIK surgery

Janika Nättinen; Antti Jylhä; Petri Mäkinen; Juhani Pietilä; Anne Huhtala; Teppo Rajala; Vesa Alho; Ulla Aapola; Roger W. Beuerman; Hannu M T Uusitalo

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5265.

ARVO Annual Meeting Abstract September 2016

Autophagy machinery is functional in human pluripotent stem cell-derived retinal pigment epithelial cells

Kati M Juuti-Uusitalo; Niko Kivinen; Johanna Viiri; Juha Hyttinen; Arto Koistinen; Hannu M T Uusitalo; Debasish Sinha; Heli Skottman; Kai Kaarniranta

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):260.

ARVO Annual Meeting Abstract September 2016

Tear fluid proteome reveals inflammation and immune response proteins as potential predictive biomarkers of the effects of desiccating stress and dry eye treatments

Ulla Aapola; Janika Nättinen; Antti Jylhä; Jose Pinto-Fraga; Alberto López-Miguel; María J González-García; Amalia Enriquez-De-Salamanca; Michael E Stern; Margarita Calonge; Hannu M T Uusitalo; Roger W Beuerman

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):397.

ARVO Annual Meeting Abstract September 2016

Conjunctival tissue proteome demonstrates abnormal expression of wound response proteins in glaucoma patients

Hannu M T Uusitalo; Antti Jylhä; Janika Nättinen; Anu Vaajanen; Miihkali Härkönen; Matti Nykter; Lei Zhou; Roger W Beuerman

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2924.

ARVO Annual Meeting Abstract September 2016

Intravitreal injection of PBS reduces retinal neovascularization in the mouse oxygen-induced retinopathy model

Maria Vähätupa; Hannele Uusitalo-Järvinen; Tero Järvinen; Hannu M T Uusitalo; Giedrius Kalesnykas

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3649.

Retina September 2016

Lack of R-Ras Leads to Increased Vascular Permeability in Ischemic Retinopathy

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Maria Vähätupa; Stuart Prince; Suvi Vataja; Teija Mertimo; Marko Kataja; Kati Kinnunen; Varpu Marjomäki; Hannu Uusitalo; Masanobu Komatsu; Tero A.H. Järvinen; Hannele Uusitalo–Järvinen
TAGS: angiogenesis, cadherins, ischemia, mice, retina, retinal diseases, vascular permeability, pericytes, cd31 antigens, diabetic retinopathy
Invest. Ophthalmol. Vis. Sci.. 2016; 57(11):4898-4909. https://doi.org/10.1167/iovs.16-19212

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2015

Tear proteome reveals predictive biomarkers for clinical improvement in glaucoma patients switching from preserved to preservative free medication

Antti Jylhä; Ulla Aapola; Janika Nättinen; Matti Nykter; Roger W Beuerman; Hannu M T Uusitalo

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3674.

ARVO Annual Meeting Abstract June 2015

Increased vascular permeability in R-Ras knockout mice with hypoxia-induced retinopathy and a lack of R-Ras expression in human diabetic retinal neovasculature

Maria Vähätupa; Stuart Prince; Marko Kataja; Kati Kinnunen; Hannu M T Uusitalo; Masanobu Komatsu; Erkki Ruoslahti; Tero Järvinen; Hannele Uusitalo-Järvinen; Ophthalmology and Anatomy, University of Tampere

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4275.

ARVO Annual Meeting Abstract June 2015

Bioengineered collagen matrices as carriers for human pluripotent stem cell derived limbal stem cells

Heli Skottman; Alexandra Mikhailova; Tanja Ilmarinen; Goran Petrovski; Hannu M T Uusitalo; Anjula Ratnayake; Mehrdad Rafat

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5637.

ARVO Annual Meeting Abstract June 2015

Ultrathin polyimide membrane as potential carrier for subretinal transplantation of human embryonic stem cell derived RPE

Tanja Ilmarinen; Hanna Hiidenmaa; Peeter Kööbi; Soile Nymark; Anni Sorkio; Jing-Huan Wang; Paivi T Alajuuma; Olli E Oksala; Hannu M T Uusitalo; Heli Skottman

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):1825.

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Association of APOE Haplotypes With Common Age-Related Ocular Diseases in 412,171 Individuals

Biological processes and clinical variables affecting trabeculectomy surgery outcome

Ocular surface characteristics in Finnish elderly population

Comparison of Capillary and Schirmer Strip Tear Fluid Sampling Methods Using SWATH-MS Proteomics Approach

Age effects on tear film proteomics

Viability of Mouse Retinal Explant Cultures Assessed by Preservation of Functionality and Morphology

Proteomic analysis of Oxygen Induced Retinopathy Model using SWATH -MS proteomics reveals novel potential therapeutic target molecules

SWATH-MS Proteomic Analysis of Oxygen-Induced Retinopathy Reveals Novel Potential Therapeutic Targets

Visual acuity, health-related quality of life, and their correlation in a nationwide epidemiological study of adult population in Finland

Tear proteome provides basis for patient stratification after switching to a unpreserved glaucoma medication

Tear film proteomics after LASIK surgery

Autophagy machinery is functional in human pluripotent stem cell-derived retinal pigment epithelial cells

Tear fluid proteome reveals inflammation and immune response proteins as potential predictive biomarkers of the effects of desiccating stress and dry eye treatments

Conjunctival tissue proteome demonstrates abnormal expression of wound response proteins in glaucoma patients

Intravitreal injection of PBS reduces retinal neovascularization in the mouse oxygen-induced retinopathy model

Lack of R-Ras Leads to Increased Vascular Permeability in Ischemic Retinopathy

Tear proteome reveals predictive biomarkers for clinical improvement in glaucoma patients switching from preserved to preservative free medication

Increased vascular permeability in R-Ras knockout mice with hypoxia-induced retinopathy and a lack of R-Ras expression in human diabetic retinal neovasculature

Bioengineered collagen matrices as carriers for human pluripotent stem cell derived limbal stem cells

Ultrathin polyimide membrane as potential carrier for subretinal transplantation of human embryonic stem cell derived RPE

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