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Articles May 2019

Digital Image Analysis of BAP-1 Accurately Predicts Uveal Melanoma Metastasis

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Gustav Stålhammar; Thonnie Rose O. See; Stephen Phillips; Stefan Seregard; Hans E. Grossniklaus
TAGS: gene expression, cohort studies, neoplasm metastasis, neoplasms, intraocular melanoma, digital image analysis, digital immunoassays
Trans. Vis. Sci. Tech.. 2019; 8(3):11. doi: 10.1167/tvst.8.3.11

Includes: Supplemental Content

Perspective January 2019

Proceedings of the Association for Research in Vision and Ophthalmology and Champalimaud Foundation Ocular Oncogenesis and Oncology Conference

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Justine R. Smith; Jacob Pe'er; Rubens N. Belfort; Fatima Cardoso; Richard D. Carvajal; Carlos Carvalho; Sarah E. Coupland; Laurence Desjardins; Jasmine H. Francis; Brenda L. Gallie; Dan S. Gombos; Hans E. Grossniklaus; Steffen Heegaard; Martine J. Jager; Swathi Kaliki; Bruce R. Ksander; Markus Maeurer; Eduardo Moreno; Jose S. Pulido; Bettina Ryll; Arun D. Singh; Junyang Zhao; António Parreira; David J. Wilson; Joan M. O'Brien
TAGS: cancer, medical oncology, neoplasms, eye cancer, vision research, carcinogenesis, ophthalmology, tumorigenesis, intraocular melanoma
Trans. Vis. Sci. Tech.. 2019; 8(1):9. doi: 10.1167/tvst.8.1.9

ARVO Annual Meeting Abstract July 2018

Investigating Lsd1 in proper retinal development and retinoblastoma differentiation

Salma Ferdous; Hans Grossniklaus; Eldon E Geisert; J M Nickerson

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1627. doi:

ARVO Annual Meeting Abstract July 2018

The Sirtuin Inhibitor Tenovin-6 as a Novel Regulator of the TP53-MDM2 Signaling Pathway in Uveal Melanoma

Matthew W Wilson; Matthew W McEwen; Zachary K. Goldsmith; Kelley Yuan; Andrew Irvine; Benjamin King; Hua Yang Yang; Hans Grossniklaus; Vanessa Marie Morales-Tirado

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3175. doi:

ARVO Annual Meeting Abstract July 2018

Uveal Melanoma Metastatic Rate is Relative to Stochastic Mutation Rate and Type of Mutation

Eszter Szalai; Yi Jiang; Natasha M. van Poppelen; Martine J. Jager; Annelies de Klein; Emine Kilic; Hans Grossniklaus

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3633. doi:

ARVO Annual Meeting Abstract July 2018

Novel ex and in vivo methods for non-invasive longitudinal tracking of RPE dysmorphology following subretinal injections

Kevin Joseph Donaldson; Henry M Skelton; Jana T Sellers; Hans Grossniklaus; J M Nickerson

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4982. doi:

Anatomy and Pathology/Oncology January 2018

BRAF , NRAS , and GNAQ Mutations in Conjunctival Melanocytic Nevi

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Jasmine H. Francis; Hans E. Grossniklaus; Larissa A. Habib; Brian Marr; David H. Abramson; Klaus J. Busam
TAGS: mutation, nevus, melanocytic nevus, conjunctiva, nevus of conjunctiva, braf gene
Invest. Ophthalmol. Vis. Sci.. 2018; 59(1):117-121. doi: 10.1167/iovs.17-22517

Retina July 2017

A Pharmacodynamic Analysis of Choroidal Neovascularization in a Porcine Model Using Three Targeted Drugs

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Jeffrey Tran; Caroline Craven; Kathy Wabner; Jenn Schmit; Brock Matter; Uday Kompella; Hans E. Grossniklaus; Timothy W. Olsen
TAGS: choroidal neovascularization, surgical procedures, operative, suidae, pazopanib
Invest. Ophthalmol. Vis. Sci.. 2017; 58(9):3732-3740. doi: 10.1167/iovs.16-21230

ARVO Annual Meeting Abstract June 2017

A Pharmacodynamic Analysis of Choroidal Neovascularization in a Porcine Model

Jeffrey Tran; Caroline Craven; Kathy Wabner; Jenn Schmit; Uday B Kompella; Hans E Grossniklaus; Timothy W Olsen

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):250. doi:

ARVO Annual Meeting Abstract June 2017

HER2 immunoreactivity and drug targeting in human retinoblastoma

Gail M Seigel; Pia Mendoza; Eszter Szalai; Dhaval K Shah; Hans E Grossniklaus

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1777. doi:

ARVO Annual Meeting Abstract June 2017

Correlation of BAP1 immunoreactivity with metastasis in uveal melanoma

Eszter Szalai; Jill R. Wells; Hans E Grossniklaus

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2503. doi:

ARVO Annual Meeting Abstract June 2017

Metastatic Uveal Melanoma in the Liver Exhibit Two Distinct Patterns with Different Growth Kinetics

Albert Liao; Pardeep Mittal; Yi Jiang; Hans E Grossniklaus

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4409. doi:

ARVO Annual Meeting Abstract June 2017

Gene Expression Profiling Reveals Heterogeneity of Nonspecific Inflammation Affecting the Lacrimal Gland

James T Rosenbaum; Dongseok Choi; Christina A Harrington; David J Wilson; Hans E Grossniklaus; Cailin H Sibley; John D Ng; Roger A Dailey; Eric A Steele; Stephen R Planck

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5617. doi:

ARVO Annual Meeting Abstract June 2017

CXCR4 expression in an intraocular melanoma mouse model with hepatic metastases

Hua Yang; Shanshan Tan; Hans E Grossniklaus; Vanessa Marie Morales; Qing Zhang; Barry L Burgess; Dan-Ning Hu; Scott E Woodman; Tara A McCannel; Jenny Yang

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1254. doi:

ARVO Annual Meeting Abstract June 2017

Microenvironmental Regulation of the Liver Inflammasomes in Uveal Melanoma Favors Metastatic Growth

Vanessa Marie Morales; Zachary K. Goldsmith; Neel Patel; Benjamin A King; Hans E Grossniklaus; Matthew W Wilson

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3959. doi:

ARVO Annual Meeting Abstract June 2017

PKC-delta as a Survival Regulator in Uveal Melanoma

Bradley Gao; Mercy Kibe; Kelley Yuan; Hans E Grossniklaus; Matthew W Wilson; Vanessa Marie Morales

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3960. doi:

Physiology and Pharmacology January 2017

Thickness and Closure Kinetics of the Suprachoroidal Space Following Microneedle Injection of Liquid Formulations

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Bryce Chiang; Nitin Venugopal; Hans E. Grossniklaus; Jae Hwan Jung; Henry F. Edelhauser; Mark R. Prausnitz
TAGS: injection of therapeutic agent, kinetics, volume, liquids
Invest. Ophthalmol. Vis. Sci.. 2017; 58(1):555-564. doi: 10.1167/iovs.16-20377

Includes: Supplemental Content

ARVO Annual Meeting Abstract September 2016

Loss of BAP1 results in high metastatic rate in a mouse ocular melanoma model

Hua Yang; Zezhong Li; Qing Zhang; Caroline M Craven; Scott E Woodman; Tara A McCannel; Hans E Grossniklaus

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4105. doi:

ARVO Annual Meeting Abstract September 2016

Metastatic Ocular Melanoma to the Liver Exhibits Infiltrative and Nodular Growth Patterns in Mouse Models

Shuo You; Qing Zhang; john lattier; Hua Yang; shin kang; Hans E Grossniklaus

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4113. doi:

ARVO Annual Meeting Abstract September 2016

Paxillin regulates UM cell survival by PKC-delta signaling

Vanessa Marie Morales; Sumana R Chintalapudi; Zachary Goldsmith; Bradley Gao; Pia Mendoza; Hans E Grossniklaus; Matthew W Wilson

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4120. doi:

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Digital Image Analysis of BAP-1 Accurately Predicts Uveal Melanoma Metastasis

Proceedings of the Association for Research in Vision and Ophthalmology and Champalimaud Foundation Ocular Oncogenesis and Oncology Conference

Investigating Lsd1 in proper retinal development and retinoblastoma differentiation

The Sirtuin Inhibitor Tenovin-6 as a Novel Regulator of the TP53-MDM2 Signaling Pathway in Uveal Melanoma

Uveal Melanoma Metastatic Rate is Relative to Stochastic Mutation Rate and Type of Mutation

Novel ex and in vivo methods for non-invasive longitudinal tracking of RPE dysmorphology following subretinal injections

BRAF , NRAS , and GNAQ Mutations in Conjunctival Melanocytic Nevi

A Pharmacodynamic Analysis of Choroidal Neovascularization in a Porcine Model Using Three Targeted Drugs

A Pharmacodynamic Analysis of Choroidal Neovascularization in a Porcine Model

HER2 immunoreactivity and drug targeting in human retinoblastoma

Correlation of BAP1 immunoreactivity with metastasis in uveal melanoma

Metastatic Uveal Melanoma in the Liver Exhibit Two Distinct Patterns with Different Growth Kinetics

Gene Expression Profiling Reveals Heterogeneity of Nonspecific Inflammation Affecting the Lacrimal Gland

CXCR4 expression in an intraocular melanoma mouse model with hepatic metastases

Microenvironmental Regulation of the Liver Inflammasomes in Uveal Melanoma Favors Metastatic Growth

PKC-delta as a Survival Regulator in Uveal Melanoma

Thickness and Closure Kinetics of the Suprachoroidal Space Following Microneedle Injection of Liquid Formulations

Loss of BAP1 results in high metastatic rate in a mouse ocular melanoma model

Metastatic Ocular Melanoma to the Liver Exhibits Infiltrative and Nodular Growth Patterns in Mouse Models

Paxillin regulates UM cell survival by PKC-delta signaling

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