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ARVO Annual Meeting Abstract June 2021

Clinical Outcomes Following Intravitreal Methotrexate Therapy for Vitreoretinal Lymphoma

Casey Anthony; Clay Bavinger; Jessica Shantha; Alfredo Voloschin; Ghazala O'Keefe; Hans E Grossniklaus; Steven Yeh

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3306. doi:

ARVO Annual Meeting Abstract June 2021

Ocular distribution and exposure of AU-011 after suprachoroidal or intravitreal administration in an orthotopic rabbit model of human uveal melanoma

Anneli Savinainen; Hans E Grossniklaus; Shin King; Joan Wicks; Cadmus C Rich

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2861. doi:

ARVO Annual Meeting Abstract June 2021

A Computational Model of BAP-1 Expression in Uveal Melanoma Reveals Early-Onset Mutagenesis

Ogul Ersin Uner; Thonnie Rose O See; Eszter Szalai; Hans E Grossniklaus; Gustav Stålhammar

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):36. doi:

Retinal Cell Biology February 2021

Morphometric Analysis of Retinal Pigment Epithelial Cells From C57BL/6J Mice During Aging

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Yong-Kyu Kim; Hanyi Yu; Vivian R. Summers; Kevin J. Donaldson; Salma Ferdous; Debresha Shelton; Nan Zhang; Micah A. Chrenek; Yi Jiang; Hans E. Grossniklaus; Jeffrey H. Boatright; Jun Kong; John M. Nickerson
TAGS: aging, mice, mice, inbred c57bl, retinal pigment cell, optic disk, eye
Invest. Ophthalmol. Vis. Sci.. 2021; 62(2):32. doi: https://doi.org/10.1167/iovs.62.2.32

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Morphometric Analysis of Anaplasia in Retinoblastoma

Aaron M Yeung; Hans Grossniklaus; Pia Mendoza; Robert D'Lorm; Gustav Stålhammar

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2804. doi:

ARVO Annual Meeting Abstract June 2020

Lysine specific demethylase 1 (Lsd1) is a potential biomarker and therapeutic target in retinoblastoma.

Salma Ferdous; Aaron Yeung; Jennifer Rha; Hans Grossniklaus; John M Nickerson

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2825. doi:

ARVO Annual Meeting Abstract June 2020

Ocular distribution and efficacy after suprachoroidal injection of AU-011 for treatment of ocular melanoma

Anneli Savinainen; Hans Grossniklaus; Shin Kang; Carol Rasmussen; Ellison Bentley; Yelena Krakova; Craig B Struble; Cadmus Rich

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3615. doi:

Biochemistry and Molecular Biology November 2019

Characterization of LSD1 Expression Within the Murine Eye

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Salma Ferdous; Hans E. Grossniklaus; Jeffrey H. Boatright; John M. Nickerson
TAGS: eye, mice, proteins, retina
Invest. Ophthalmol. Vis. Sci.. 2019; 60(14):4619-4631. doi: https://doi.org/10.1167/iovs.19-26728

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Her2 expression in retinoblastoma and adjacent "normal" retina detected by in situ hybridization

Gail M Seigel; Dhavalkumar Shah; Pia Mendoza; Hans E Grossniklaus; Yinghui Song; Jidong Shan

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2318. doi:

ARVO Annual Meeting Abstract July 2019

BAP1 Immunoreactivity correlates with gene expression class in uveal melanoma

Hans E Grossniklaus; Thonnie R See; Gustav Stalhammar; Stephen S Phillips

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):750. doi:

ARVO Annual Meeting Abstract July 2019

Digital image analysis of BAP-1 accurately predicts uveal melanoma metastasis

Gustav Stålhammar; Thonnie Rose See; Stephen S Phillips; Hans E Grossniklaus

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):751. doi:

ARVO Annual Meeting Abstract July 2019

Subpopulations of uveal melanoma cells have distinct roles and cooperate to promote hematogenous dissemination

Stephen S Phillips; Gustav Stålhammar; Thonnie Rose See; Hans E Grossniklaus

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):959. doi:

ARVO Annual Meeting Abstract July 2019

Novel in and ex vivo methods to reveal abnormal RPE morphology and microglial cell migration following light-induced retinal damage

Wenfei Wu; Kevin Joseph Donaldson; Kristie Ling Liao; Isabelle Gefke; Jeffrey H Boatright; Hans E Grossniklaus; John M Nickerson

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2382. doi:

ARVO Annual Meeting Abstract July 2019

Treatment of retinoblastoma cells with TCP induces dose-dependent cell death

Jennifer Rha; Salma Ferdous; Micah A Chrenek; Maxwell Griffin; Jeffrey H Boatright; Hans E Grossniklaus; John M Nickerson

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2337. doi:

ARVO Annual Meeting Abstract July 2019

Characterization and functional analysis of Lsd1 within the murine eye

Salma Ferdous; Isabelle Gefke; Jeffrey H Boatright; Hans E Grossniklaus; John M Nickerson

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2346. doi:

Articles May 2019

Digital Image Analysis of BAP-1 Accurately Predicts Uveal Melanoma Metastasis

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Gustav Stålhammar; Thonnie Rose O. See; Stephen Phillips; Stefan Seregard; Hans E. Grossniklaus
TAGS: cohort studies, digital image analysis, digital immunoassays, gene expression, intraocular melanoma, neoplasm metastasis, neoplasms
Trans. Vis. Sci. Tech.. 2019; 8(3):11. doi: https://doi.org/10.1167/tvst.8.3.11

Includes: Supplemental Content

Perspective January 2019

Proceedings of the Association for Research in Vision and Ophthalmology and Champalimaud Foundation Ocular Oncogenesis and Oncology Conference

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Justine R. Smith; Jacob Pe'er; Rubens N. Belfort; Fatima Cardoso; Richard D. Carvajal; Carlos Carvalho; Sarah E. Coupland; Laurence Desjardins; Jasmine H. Francis; Brenda L. Gallie; Dan S. Gombos; Hans E. Grossniklaus; Steffen Heegaard; Martine J. Jager; Swathi Kaliki; Bruce R. Ksander; Markus Maeurer; Eduardo Moreno; Jose S. Pulido; Bettina Ryll; Arun D. Singh; Junyang Zhao; António Parreira; David J. Wilson; Joan M. O'Brien
TAGS: carcinogenesis, medical oncology, ophthalmology, tumorigenesis, vision research, intraocular melanoma, neoplasms, cancer, eye cancer
Trans. Vis. Sci. Tech.. 2019; 8(1):9. doi: https://doi.org/10.1167/tvst.8.1.9

ARVO Annual Meeting Abstract July 2018

The Sirtuin Inhibitor Tenovin-6 as a Novel Regulator of the TP53-MDM2 Signaling Pathway in Uveal Melanoma

Matthew W Wilson; Matthew W McEwen; Zachary K. Goldsmith; Kelley Yuan; Andrew Irvine; Benjamin King; Hua Yang Yang; Hans Grossniklaus; Vanessa Marie Morales-Tirado

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3175. doi:

ARVO Annual Meeting Abstract July 2018

Uveal Melanoma Metastatic Rate is Relative to Stochastic Mutation Rate and Type of Mutation

Eszter Szalai; Yi Jiang; Natasha M. van Poppelen; Martine J. Jager; Annelies de Klein; Emine Kilic; Hans Grossniklaus

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3633. doi:

ARVO Annual Meeting Abstract July 2018

Novel ex and in vivo methods for non-invasive longitudinal tracking of RPE dysmorphology following subretinal injections

Kevin Joseph Donaldson; Henry M Skelton; Jana T Sellers; Hans Grossniklaus; J M Nickerson

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4982. doi:

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Clinical Outcomes Following Intravitreal Methotrexate Therapy for Vitreoretinal Lymphoma

Ocular distribution and exposure of AU-011 after suprachoroidal or intravitreal administration in an orthotopic rabbit model of human uveal melanoma

A Computational Model of BAP-1 Expression in Uveal Melanoma Reveals Early-Onset Mutagenesis

Morphometric Analysis of Retinal Pigment Epithelial Cells From C57BL/6J Mice During Aging

Morphometric Analysis of Anaplasia in Retinoblastoma

Lysine specific demethylase 1 (Lsd1) is a potential biomarker and therapeutic target in retinoblastoma.

Ocular distribution and efficacy after suprachoroidal injection of AU-011 for treatment of ocular melanoma

Characterization of LSD1 Expression Within the Murine Eye

Her2 expression in retinoblastoma and adjacent "normal" retina detected by in situ hybridization

BAP1 Immunoreactivity correlates with gene expression class in uveal melanoma

Digital image analysis of BAP-1 accurately predicts uveal melanoma metastasis

Subpopulations of uveal melanoma cells have distinct roles and cooperate to promote hematogenous dissemination

Novel in and ex vivo methods to reveal abnormal RPE morphology and microglial cell migration following light-induced retinal damage

Treatment of retinoblastoma cells with TCP induces dose-dependent cell death

Characterization and functional analysis of Lsd1 within the murine eye

Digital Image Analysis of BAP-1 Accurately Predicts Uveal Melanoma Metastasis

Proceedings of the Association for Research in Vision and Ophthalmology and Champalimaud Foundation Ocular Oncogenesis and Oncology Conference

The Sirtuin Inhibitor Tenovin-6 as a Novel Regulator of the TP53-MDM2 Signaling Pathway in Uveal Melanoma

Uveal Melanoma Metastatic Rate is Relative to Stochastic Mutation Rate and Type of Mutation

Novel ex and in vivo methods for non-invasive longitudinal tracking of RPE dysmorphology following subretinal injections

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