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ARVO Annual Meeting Abstract June 2025

Restoration of Mitochondrial Function in Endothelial Cells Preserves Blood-Retinal Barrier Integrity and Prevents Neurodegeneration in Glaucoma

Isaac Alejandro Vidal Paredes; Jorge Luis Cueva Vargas; Nicolas Belforte; Florence Dotigny; Heberto Quintero; Adriana Di Polo

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1854.

ARVO Annual Meeting Abstract June 2025

Exploring Small-Molecule Mitochondrial Uncouplers for Glaucoma Neuroprotection

Heberto Quintero; Renata Ghenno-Manrique; Yukihiro Shiga; Isaac Alejandro Vidal Paredes; Nicolas Belforte; Jorge Luis Cueva Vargas; John G Geisler; Adriana Di Polo

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):3409.

ARVO Annual Meeting Abstract June 2024

Mitochondrial uncoupler MP201 promotes retinal ganglion cell neuroprotection in experimental glaucoma

Heberto Quintero; Renata Ghenno-Manrique; Nicolas Belforte; Jorge L. Cueva-Vargas; Robert Alonso; John G. Geisler; Adriana Di Polo

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):670.

ARVO Annual Meeting Abstract June 2024

Restoration of Blood-Retinal Barrier Integrity Prevents Neurodegeneration in Glaucoma

Isaac Alejandro Vidal Paredes; Jorge Luis Cueva Vargas; Nicolas Belforte; Yukihiro Shiga; Florence Dotigny; Heberto Quintero; Adriana Di Polo

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):393.

ARVO Annual Meeting Abstract June 2024

Chemogenetic-induced retinal ganglion cell excitation reveals IP3R-dependent dysregulation of calcium dynamics linked to neuronal metabolic stress in glaucoma

Yukihiro Shiga; Jorge Luis Cueva Vargas; Sana El Hajji; Nicolas Belforte; Florence Dotigny; Heberto Quintero; Adriana Di Polo

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3253.

ARVO Annual Meeting Abstract June 2023

Calcium clearance deficits linked to endoplasmic reticulum stress are signature features of early retinal ganglion cell damage in glaucoma

Yukihiro Shiga; Aline Giselle Rangel Olguin; Sana El Hajji; Nicolas Belforte; Heberto Quintero; Florence Dotigny; Luis Alarcon-Martinez; Arjun Krishnaswamy; Adriana Di Polo

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):482.

ARVO Annual Meeting Abstract June 2023

Glial cells regulate pericyte-driven capillary deficits in glaucoma

Deborah Villafranca-Baughman; Luis Alarcon-Martinez; Nicolas Belforte; Heberto Quintero; Florence Dotigny; Adriana Di Polo

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3259.

ARVO Annual Meeting Abstract June 2022

Restoration of mitochondrial axonal transport by adaptor supplementation prevents neurodegeneration and rescues visual function in glaucoma

Heberto Quintero; Yukihiro Shiga; Nicolas A Belforte; Luis Alarcon-Martinez; Sana El Hajji; Deborah Villafranca-Baughman; Florence Dotigny; Adriana Di Polo

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):12.

ARVO Annual Meeting Abstract June 2022

Light-evoked RGC calcium dynamics are altered in glaucoma: live imaging evidence of abnormal calcium clearance

Yukihiro Shiga; Aline Giselle Rangel Olguin; Luis Alarcon-Martinez; Nicolas A Belforte; Heberto Quintero; Deborah Villafranca-Baughman; Florence Dotigny; Arjun Krishnaswamy; Adriana Di Polo

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1850.

ARVO Annual Meeting Abstract June 2021

Pericyte dysfunction promotes neurovascular deficits in glaucoma

Luis Alarcon-Martinez; Yukihiro Shiga; Nicolas Belforte; Deborah Villafranca-Baughman; Jorge Cueva Vargas; Heberto Quintero; Florence Dotigny; Adriana Di Polo

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1864.

ARVO Annual Meeting Abstract June 2021

Increased DISC1 expression restores mitochondrial axonal transport and rescues RGC function in glaucoma

Heberto Quintero; Nicolas Belforte; Luis Alarcon-Martinez; Florence Dotigny; Sana El Hajji; Adriana Di Polo

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1767.

ARVO Annual Meeting Abstract June 2021

Live two-photon calcium imaging in retinal ganglion cells: characterization of early changes in a mouse glaucoma model.

Yukihiro Shiga; Luis Alarcon-Martinez; Nicolas Belforte; Heberto Quintero; Deborah Villafranca-Baughman; Florence Dotigny; Adriana Di Polo

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2344.

ARVO Annual Meeting Abstract June 2021

Insulin for retinal ganglion cell dendrite regeneration: effect of intraocular pressure and identification of multiple downstream pathways

Sana El Hajji; Nicolas Belforte; Heberto Quintero; Florence Dotigny; Adriana Di Polo

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2258.

ARVO Annual Meeting Abstract June 2020

Role of insulin on retinal ganglion cell dendrite regeneration: effect of intraocular pressure regulation and identification of molecular mechanisms

Sana EL HAJJI; Nicolas Belforte; Heberto Quintero; Florence Dotigny; Adriana Di Polo

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1164.

ARVO Annual Meeting Abstract June 2020

Increased expression of DISC1 restores mitochondrial axonal transport and promotes RGC survival in glaucoma: a live imaging study

Heberto Q Quintero; Nicolas Belforte; Luis Alarcon-Martinez; Sana EL HAJJI; Adriana Di Polo

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1162.

ARVO Annual Meeting Abstract July 2018

The ability of retinal ganglion cells to regenerate dendrites and synapses requires insulin signaling and is impaired by high fat diet intake

Jessica Agostinone; Luis Alarcon-Martinez; Heberto Quintero; Sara Vucetic; Nicolas A Belforte; Adriana Di Polo

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2613.

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