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ARVO Annual Meeting Abstract June 2024

Molecular and Cellular Mechanisms of Levodopa-Mediated Visual Function Rescue in Albinism

Sarah Macdonald; Eloise Keeling; Jennifer A Scott; Helen Griffiths; Andrew Lotery; J. Arjuna Ratnayaka; James Edward Self; Helena Lee

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):821.

ARVO Annual Meeting Abstract June 2023

Use of a handheld electrophysiology device (RETeval, LKC) to identify visual pathway decussation defects

Eloise Keeling; Perry Carter; Fatima Shawkat; Helena Lee; James Self

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5325.

ARVO Annual Meeting Abstract June 2023

Eyetracking-enhanced VEP for nystagmus

Perry Carter; Fatima Shawkat; James Self; Helena Lee; Eloise Keeling; Matt Dunn

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):43.

ARVO Annual Meeting Abstract July 2019

Characterization of the retinal phenotype of the C57BL/6-c2J mouse model of human oculocutaneous albinism: implications for treatment development

Jennifer Ann Scott; Aida Sanchez-Bretano; Helen Griffiths; Jon Ward; Chiamaka Dibigbou; Flavie Soubigou; James Edward Self; Andrew Lotery; J. Arjuna Ratnayaka; Helena Lee

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):529.

ARVO Annual Meeting Abstract July 2019

Proof of concept for oral Levodopa treatment in rescuing retinal morphology and visual function in a murine model of human albinism

Helena Lee; Jennifer Scott; Helen Griffiths; James Edward Self; Andrew Lotery

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):530.

ARVO Annual Meeting Abstract July 2019

Oral human-equivalent L-DOPA/Carbidopa dosages administered during the postnatal critical period of neuroplasticity rescues retinal morphology and visual function in a mouse model of human albinism

Aida Sanchez-Bretano; Jennifer Ann Scott; Tutte Newall; Savannah Lynn; Helen Griffiths; Ahmed Salman; Andrew Lotery; J. Arjuna Ratnayaka; James Edward Self; Helena Lee

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1393.

ARVO Annual Meeting Abstract July 2018

Comparison of quantitative segmentation analysis and structural grading of foveal hypoplasia in infants for the prediction of future visual acuity: A longitudinal cohort study

Sohaib Riyaz Rufai; Mervyn George Thomas; Ravi Purohit; Helena Lee; Frank A Proudlock; Irene Gottlob

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5788.

ARVO Annual Meeting Abstract July 2018

Subretinal Aβ injections induce a localised, early CNV phenotype in C57BL/6 mice

Savannah Lynn; Jennifer Scott; Helena [email protected] Lee; Roshni Desai; Tracey Newman; Angela Cree; Andrew Lotery; J. Arjuna Ratnayaka

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5827.

ARVO Annual Meeting Abstract June 2017

Can grading foveal hypoplasia in infants using handheld optical coherence tomography predict future visual acuity? A longitudinal cohort study

Sohaib Riyaz Rufai; Mervyn G Thomas; Helena Lee; Frank A Proudlock; Irene Gottlob

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5643.

ARVO Annual Meeting Abstract June 2017

Optic Nerve Head Development of Premature and Full Term Infants from Term to Six Years of Age Using Hand-Held Ultra-High Resolution Spectral Domain Optical Coherence Tomography

Aarti Patel; Samira Anwar; Helena [email protected] Lee; Frank A Proudlock; Irene Gottlob

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5530.

ARVO Annual Meeting Abstract June 2017

Murine Retinal Development, Morphology and Function in Albinism: Potential Implications for Therapeutic Development

Helena [email protected] Lee; Jennifer Scott; Helen Griffiths; Andrew J Lotery

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5570.

ARVO Annual Meeting Abstract September 2016

Retinal Development in Albinism: Evidence for Residual Plasticity in Early Childhood?

Helena Lee; Ravi Purohit; Viral Sheth; Gail Maconachie; Anastasia Pilat; Rebecca McLean; Frank A Proudlock; Irene Gottlob

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5980.

ARVO Annual Meeting Abstract September 2016

A systematic review to assess the “Treat-and-Extend” dosing regimen compared to monthly and as-needed dosing for neovascular age-related macular degeneration using ranibizumab

Sohaib Riyaz Rufai; Hussein Almuhtaseb; Helena Lee; Richard Paul; Beth Stuart; Tony Kendrick; Andrew J Lotery

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3367.

Articles July 2016

Pediatric Optical Coherence Tomography in Clinical Practice—Recent Progress

PDF

Helena Lee; Frank A. Proudlock; Irene Gottlob
TAGS: child, diagnostic imaging, optical coherence tomography, pediatrics, optic nerve, pathologic nystagmus, retinopathy of prematurity, infant
Invest. Ophthalmol. Vis. Sci.. 2016; 57(9):OCT69-OCT79. https://doi.org/10.1167/iovs.15-18825

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology April 2016

Abnormally Small Neuromuscular Junctions in the Extraocular Muscles From Subjects With Idiopathic Nystagmus and Nystagmus Associated With Albinism

PDF

Linda K. McLoon; Christy L. Willoughby; Jill S. Anderson; Erick D. Bothun; David Stager, Jr; Joost Felius; Helena Lee; Irene Gottlob
TAGS: albinism, muscle of orbit, neuromuscular junction, pathologic nystagmus
Invest. Ophthalmol. Vis. Sci.. 2016; 57(4):1912-1920. https://doi.org/10.1167/iovs.16-19129

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology July 2015

Characterization of Abnormal Optic Nerve Head Morphology in Albinism Using Optical Coherence Tomography

PDF

Sarim Mohammad; Irene Gottlob; Viral Sheth; Anastasia Pilat; Helena Lee; Ellen Pollheimer; Frank Anthony Proudlock
TAGS: albinism, language morphology, morphology, optic disk, optic nerve hypoplasia, optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2015; 56(8):4611-4618. https://doi.org/10.1167/iovs.15-16856

Includes: Supplemental Content

Retina July 2015

In Vivo Foveal Development Using Optical Coherence Tomography

PDF

Helena Lee; Ravi Purohit; Aarti Patel; Eleni Papageorgiou; Viral Sheth; Gail Maconachie; Anastasia Pilat; Rebecca J. McLean; Frank A. Proudlock; Irene Gottlob
TAGS: fovea centralis, infant, optical coherence tomography, retina, child
Invest. Ophthalmol. Vis. Sci.. 2015; 56(8):4537-4545. https://doi.org/10.1167/iovs.15-16542

Includes: Multimedia, Supplemental Content

ARVO Annual Meeting Abstract June 2015

Retinal Development in Achromatopsia: A Prospective Study of Infants and Young Children using Optical Coherence Tomography

Helena Lee; Ravi Purohit; Viral Sheth; Rebecca Jane McLean; Gail Maconachie; Susanne Kohl; Bart Peter Leroy; Michel Michaelides; Frank A Proudlock; Irene Gottlob

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5855.

ARVO Annual Meeting Abstract April 2014

Exploring retinal development of strabismic infants using handheld optical coherence tomography

Gail Maconachie; Viral Sheth; Ravi Purohit; Helena Lee; Frank A Proudlock; Irene Gottlob

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):4547.

ARVO Annual Meeting Abstract April 2014

The developing optic nerve head in infantile idiopathic nystagmus and nystagmus associated to albinism

Ravi Purohit; Helena Lee; Aarti Patel; Viral Sheth; Gail Maconachie; Eleni Papageorgiou; Rebecca J McLean; Irene Gottlob; Frank A Proudlock

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):5980.

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Molecular and Cellular Mechanisms of Levodopa-Mediated Visual Function Rescue in Albinism

Use of a handheld electrophysiology device (RETeval, LKC) to identify visual pathway decussation defects

Eyetracking-enhanced VEP for nystagmus

Characterization of the retinal phenotype of the C57BL/6-c2J mouse model of human oculocutaneous albinism: implications for treatment development

Proof of concept for oral Levodopa treatment in rescuing retinal morphology and visual function in a murine model of human albinism

Oral human-equivalent L-DOPA/Carbidopa dosages administered during the postnatal critical period of neuroplasticity rescues retinal morphology and visual function in a mouse model of human albinism

Comparison of quantitative segmentation analysis and structural grading of foveal hypoplasia in infants for the prediction of future visual acuity: A longitudinal cohort study

Subretinal Aβ injections induce a localised, early CNV phenotype in C57BL/6 mice

Can grading foveal hypoplasia in infants using handheld optical coherence tomography predict future visual acuity? A longitudinal cohort study

Optic Nerve Head Development of Premature and Full Term Infants from Term to Six Years of Age Using Hand-Held Ultra-High Resolution Spectral Domain Optical Coherence Tomography

Murine Retinal Development, Morphology and Function in Albinism: Potential Implications for Therapeutic Development

Retinal Development in Albinism: Evidence for Residual Plasticity in Early Childhood?

A systematic review to assess the “Treat-and-Extend” dosing regimen compared to monthly and as-needed dosing for neovascular age-related macular degeneration using ranibizumab

Pediatric Optical Coherence Tomography in Clinical Practice—Recent Progress

Abnormally Small Neuromuscular Junctions in the Extraocular Muscles From Subjects With Idiopathic Nystagmus and Nystagmus Associated With Albinism

Characterization of Abnormal Optic Nerve Head Morphology in Albinism Using Optical Coherence Tomography

In Vivo Foveal Development Using Optical Coherence Tomography

Retinal Development in Achromatopsia: A Prospective Study of Infants and Young Children using Optical Coherence Tomography

Exploring retinal development of strabismic infants using handheld optical coherence tomography

The developing optic nerve head in infantile idiopathic nystagmus and nystagmus associated to albinism

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