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Glaucoma June 2018

YAP/TAZ Are Essential for TGF-β2–Mediated Conjunctival Fibrosis

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Akiko Futakuchi; Toshihiro Inoue; Fan-Yan Wei; Miyuki Inoue-Mochita; Tomokazu Fujimoto; Kazuhito Tomizawa; Hidenobu Tanihara
TAGS: conjunctiva, fibroblasts, fibrosis, proteins, signal transduction, verteporfin
Invest. Ophthalmol. Vis. Sci.. 2018; 59(7):3069-3078. doi: https://doi.org/10.1167/iovs.18-24258

Includes: Supplemental Content

Glaucoma April 2018

Interaction Between Pilocarpine and Ripasudil on Intraocular Pressure, Pupil Diameter, and the Aqueous-Outflow Pathway

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Reiko Yamagishi-Kimura; Megumi Honjo; Takashi Komizo; Takashi Ono; Akiko Yagi; Jinhee Lee; Kazunori Miyata; Tomokazu Fujimoto; Toshihiro Inoue; Hidenobu Tanihara; Junko Nishida; Takatoshi Uchida; Yuka Araki; Makoto Aihara
TAGS: pilocarpine, intraocular pressure, pupil
Invest. Ophthalmol. Vis. Sci.. 2018; 59(5):1844-1854. doi: https://doi.org/10.1167/iovs.18-23900

Glaucoma August 2017

Determinants and Characteristics of Bruch's Membrane Opening and Bruch's Membrane Opening–Minimum Rim Width in a Normal Japanese Population

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Makoto Araie; Aiko Iwase; Kazuhisa Sugiyama; Toru Nakazawa; Goji Tomita; Masanori Hangai; Yasuo Yanagi; Hiroshi Murata; Hidenobu Tanihara; Claude F. Burgoyne; Balwantray C. Chauhan
TAGS: bruch's basal membrane, japanese, optic disk, eye, glaucoma, spectral domain-optical coherence tomography, retinal nerve fiber layer
Invest. Ophthalmol. Vis. Sci.. 2017; 58(10):4106-4113. doi: https://doi.org/10.1167/iovs.17-22057

Glaucoma April 2017

Molecular Mechanisms Underlying the Filtration Bleb-Maintaining Effects of Suberoylanilide Hydroxamic Acid (SAHA)

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Akiko Futakuchi; Toshihiro Inoue; Tomokazu Fujimoto; Utako Kuroda; Miyuki Inoue-Mochita; Eri Takahashi; Saori Ohira; Hidenobu Tanihara
TAGS: vorinostat, blister, filtration
Invest. Ophthalmol. Vis. Sci.. 2017; 58(4):2421-2429. doi: https://doi.org/10.1167/iovs.16-21403

Glaucoma November 2016

Potential Neuroprotective Effects of an LSD1 Inhibitor in Retinal Ganglion Cells via p38 MAPK Activity

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Takayuki Tsutsumi; Keiichiro Iwao; Hideki Hayashi; Tomoko Kirihara; Takahiro Kawaji; Toshihiro Inoue; Shinjiro Hino; Mitsuyoshi Nakao; Hidenobu Tanihara
TAGS: neuroprotective effect, tranylcypromine, mitogen-activated protein kinase p38, retinal ganglion cells
Invest. Ophthalmol. Vis. Sci.. 2016; 57(14):6461-6473. doi: https://doi.org/10.1167/iovs.16-19494

Includes: Supplemental Content

ARVO Annual Meeting Abstract September 2016

Vascular Endothelial Growth Factor-A Increases Aqueous humor Outflow Fcility

Tomokazu Fujimoto; Toshihiro Inoue; KEI MAKI; Miyuki Mochita Inoue; Hidenobu Tanihara

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4689. doi:

ARVO Annual Meeting Abstract September 2016

Effects of interleukin-6 signaling activity on fibrogenic activity of human trabecular meshwork cells

Toshihiro Inoue; Miyuki Mochita Inoue; Tomokazu Fujimoto; Hidenobu Tanihara

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4693. doi:

ARVO Annual Meeting Abstract September 2016

Four-dimensional imaging revealed influences of monocyte chemoattractant protein-1 on immune cell dynamics in the subconjunctival tissue.

Sachi Kojima; Toshihiro Inoue; Tomokazu Fujimoto; Hidenobu Tanihara

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5148. doi:

ARVO Annual Meeting Abstract September 2016

Increasing the population of retinal ganglion-like cells among retinal cells differentiated from mouse ES cells using 3D culture method

Satoshi Iraha; Michiko Mandai; Hidenobu Tanihara; Masayo Takahashi

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6073. doi:

ARVO Annual Meeting Abstract September 2016

Effects of ripasudil (K-115), a Rho kinase inhibitor, on the activation of human conjunctival fibroblasts

Akiko Futakuchi; Toshihiro Inoue; Tomokazu Fujimoto; Miyuki Mochita Inoue; Hidenobu Tanihara

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2929. doi:

ARVO Annual Meeting Abstract September 2016

Trabeculectomy in Both Eyes; the First-Operated Versus the Second-Operated Eyes: A Comparative, Multicenter Study.

Kentaro Iwasaki; Yoshihiro Takamura; Takashi Nishida; Akira Sawada; Keiichiro Iwao; Ayano Shinmura; Shiho Kunimatsu-Sanuki; Hidenobu Tanihara; Kazuhisa Sugiyama; Toru Nakazawa; Masaru Inatani

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2949. doi:

ARVO Annual Meeting Abstract September 2016

Specific clinical features of intraocular pressure-lowering effect in ripasudil (K-115): insights from 52-week phase 3 study

Hidenobu Tanihara; Toshihiro Inoue; Tetsuya Yamamoto; Yasuaki Kuwayama; Haruki Abe; Atsuki Fukushima; Hideki Suganami; Makoto Araie

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3033. doi:

Immunology and Microbiology May 2016

Differentiated Expression Patterns and Phagocytic Activities of Type 1 and 2 Microglia

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Akira Haga; Eri Takahashi; Yasuya Inomata; Koichi Kawahara; Hidenobu Tanihara
TAGS: interleukin-4, microglia
Invest. Ophthalmol. Vis. Sci.. 2016; 57(6):2814-2823. doi: https://doi.org/10.1167/iovs.15-18509

Multidisciplinary Ophthalmic Imaging March 2016

Visualization of Intravital Immune Cell Dynamics After Conjunctival Surgery Using Multiphoton Microscopy

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Sachi Kojima; Toshihiro Inoue; Junichi Kikuta; Masayuki Furuya; Ayaka Koga; Tomokazu Fujimoto; Mayumi Ueta; Shigeru Kinoshita; Masaru Ishii; Hidenobu, Tanihara
TAGS: conjunctiva, diagnostic imaging, surgical procedures, operative, wounds and injuries, mice, body tissue
Invest. Ophthalmol. Vis. Sci.. 2016; 57(3):1207-1212. doi: https://doi.org/10.1167/iovs.15-18507

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2015

Totally organized mitochondrial axonal transport patterns in retinal ganglion cells of old mice in vivo

Yuji Takihara; Masaru Inatani; Toshihiro Inoue; Keiichiro Iwao; Yoshihiro Takamura; Hidenobu Tanihara

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3661. doi:

ARVO Annual Meeting Abstract June 2015

Merlin regulates hyaluronan endocytosis and epithelial mesenchymal transition in ARPE-19 cells

Eri Takahashi; Akira Haga; Hidenobu Tanihara

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4239. doi:

ARVO Annual Meeting Abstract June 2015

TGF-β-activated kinase 1 is essential for tumor necrosis factor-α-induced epithelial mesenchymal transition in ARPE-19 cells

KOKI MATSUBARA; Eri Takahashi; Akira Haga; Hidenobu Tanihara

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4240. doi:

ARVO Annual Meeting Abstract June 2015

The subtypes of retinal microglia in rat after optic nerve crush injury

Akira Haga; Eri Takahashi; Yasuya Inomata; Hidenobu Tanihara

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4946. doi:

ARVO Annual Meeting Abstract June 2015

Bruch’s Membrane Opening-Based Neuroretinal Rim Width and Retinal Nerve Fibre Layer Thickness in a Normal Japanese Population. A Multi-Centre Study

Balwantray C Chauhan; Masanori Hangai; Aiko Iwase; Toru Nakazawa; Kazuhisa Sugiyama; Hidenobu Tanihara; Goji Tomita; Yasuo Yanagi; Claude F Burgoyne; Makoto Araie

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):1014. doi:

ARVO Annual Meeting Abstract June 2015

The Effect of VEGF-A on Trabecular Meshwork and Schlemm’s Canal Endothelial Cells Permeability

Tomokazu Fujimoto; Toshihiro Inoue; Kei Maki; Sachi Kojima; Miyuki Inoue-Mochita; Hidenobu Tanihara

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2008. doi:

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YAP/TAZ Are Essential for TGF-β2–Mediated Conjunctival Fibrosis

Interaction Between Pilocarpine and Ripasudil on Intraocular Pressure, Pupil Diameter, and the Aqueous-Outflow Pathway

Determinants and Characteristics of Bruch's Membrane Opening and Bruch's Membrane Opening–Minimum Rim Width in a Normal Japanese Population

Molecular Mechanisms Underlying the Filtration Bleb-Maintaining Effects of Suberoylanilide Hydroxamic Acid (SAHA)

Potential Neuroprotective Effects of an LSD1 Inhibitor in Retinal Ganglion Cells via p38 MAPK Activity

Vascular Endothelial Growth Factor-A Increases Aqueous humor Outflow Fcility

Effects of interleukin-6 signaling activity on fibrogenic activity of human trabecular meshwork cells

Four-dimensional imaging revealed influences of monocyte chemoattractant protein-1 on immune cell dynamics in the subconjunctival tissue.

Increasing the population of retinal ganglion-like cells among retinal cells differentiated from mouse ES cells using 3D culture method

Effects of ripasudil (K-115), a Rho kinase inhibitor, on the activation of human conjunctival fibroblasts

Trabeculectomy in Both Eyes; the First-Operated Versus the Second-Operated Eyes: A Comparative, Multicenter Study.

Specific clinical features of intraocular pressure-lowering effect in ripasudil (K-115): insights from 52-week phase 3 study

Differentiated Expression Patterns and Phagocytic Activities of Type 1 and 2 Microglia

Visualization of Intravital Immune Cell Dynamics After Conjunctival Surgery Using Multiphoton Microscopy

Totally organized mitochondrial axonal transport patterns in retinal ganglion cells of old mice in vivo

Merlin regulates hyaluronan endocytosis and epithelial mesenchymal transition in ARPE-19 cells

TGF-β-activated kinase 1 is essential for tumor necrosis factor-α-induced epithelial mesenchymal transition in ARPE-19 cells

The subtypes of retinal microglia in rat after optic nerve crush injury

Bruch’s Membrane Opening-Based Neuroretinal Rim Width and Retinal Nerve Fibre Layer Thickness in a Normal Japanese Population. A Multi-Centre Study

The Effect of VEGF-A on Trabecular Meshwork and Schlemm’s Canal Endothelial Cells Permeability

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