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Articles April 2021

Omidenepag, a Selective, Prostanoid EP2 Agonist, Does Not Suppress Adipogenesis in 3D Organoids of Human Orbital Fibroblasts

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Fumihito Hikage; Yosuke Ida; Yuika Ouchi; Megumi Watanabe; Hiroshi Ohguro
TAGS: agonists, fibroblasts, organoids, prostaglandins
Trans. Vis. Sci. Tech.. 2021; 10(4):6. https://doi.org/10.1167/tvst.10.4.6

Includes: Supplemental Content

Glaucoma June 2020

Prostaglandin F2α Agonists Negatively Modulate the Size of 3D Organoids from Primary Human Orbital Fibroblasts

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Kaku Itoh; Fumihito Hikage; Yosuke Ida; Hiroshi Ohguro
TAGS: agonists, fibroblasts, organoids, prostaglandins, prostaglandins, synthetic
Invest. Ophthalmol. Vis. Sci.. 2020; 61(6):13. https://doi.org/10.1167/iovs.61.6.13

Includes: Supplemental Content

Retina October 2014

IκB Kinase-β Inhibitor IMD-0354 Beneficially Suppresses Retinal Vascular Permeability in Streptozotocin-Induced Diabetic Mice

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Anton Lennikov; Miki Hiraoka; Akira Abe; Shigeaki Ohno; Tomoyuki Fujikawa; Akiko Itai; Hiroshi Ohguro
TAGS: diabetes mellitus, mice, phosphotransferases, streptozocin, vascular permeability
Invest. Ophthalmol. Vis. Sci.. 2014; 55(10):6365-6373. https://doi.org/10.1167/iovs.14-14671

Biochemistry and Molecular Biology January 2012

Lysosomal Phospholipase A2 Activity in Pig Aqueous Humor

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Akira Abe; Miki Hiraoka; Shuichiro Inatomi; Ikuyo Ohguro; Hiroshi Ohguro
TAGS: aqueous humor, body tissue, hypertension, phospholipase, liposomes, enzymes
Invest. Ophthalmol. Vis. Sci.. 2012; 53(1):152-156. https://doi.org/10.1167/iovs.11-7891

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology September 2011

Fetal Check Ligament Connected between the Conjunctiva and the Medial and Lateral Recti

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Hajime Osanai; Jose Francisco Rodríguez-Vázquez; Hiroshi Abe; Gen Murakami; Hiroshi Ohguro; Mineko Fujimiya
TAGS: conjunctiva, fetus, ligaments, connective tissue, muscle, eye, silver staining
Invest. Ophthalmol. Vis. Sci.. 2011; 52(10):7175-7179. https://doi.org/10.1167/iovs.11-7426

ARVO Annual Meeting Abstract April 2011

Identification Of Autoantibodies Against Trpm1 In Patients With Paraneoplastic Retinopathy Associated With On Bipolar Cell Dysfunction

Mineo Kondo; Rikako Sanuki; Shinji Ueno; Yuji Nishizawa; Hiroshi Ohguro; Shuichi Yamamoto; Shigeki Machida; Hiroko Terasaki; Grazyna Adamus; Takahisa Furukawa

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):6667.

Anatomy and Pathology/Oncology March 2011

Human Orbital Muscle: A New Point of View from the Fetal Development of Extraocular Connective Tissues

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Hajime Osanai; Shin-ichi Abe; Jose Rodríguez-Vázquez; Samuel Verdugo-López; Gen Murakami; Hiroshi Ohguro
TAGS: connective tissue, fetal development, muscle, fetus, adipose tissue, smooth muscle
Invest. Ophthalmol. Vis. Sci.. 2011; 52(3):1501-1506. https://doi.org/10.1167/iovs.10-6013

Lens May 2007

Inhibitory Effects of Retinoic Acid Receptor Alpha Stimulants on Murine Cataractogenesis through Suppression of Deregulated Calpains

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Nami Nishikiori; Makoto Osanai; Hideki Chiba; Takashi Kojima; Hiroshi Ohguro; Norimasa Sawada
TAGS: calpain, central nervous system stimulants, retinoic acid receptor, tretinoin
Invest. Ophthalmol. Vis. Sci.. 2007; 48(5):2224-2229. https://doi.org/10.1167/iovs.06-1222

Biochemistry and Molecular Biology December 2006

Prolonged Rhodopsin Phosphorylation in Light-Induced Retinal Degeneration in Rat Models

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Futoshi Ishikawa; Hiroshi Ohguro; Ikuyo Ohguro; Hitoshi Yamazaki; Kazuhisa Mamiya; Tomomi Metoki; Tadashi Ito; Yumiko Yokoi; Mitsuru Nakazawa
TAGS: phosphorylation, rats, retinal degeneration, rhodopsin, stress, electroretinography, antibodies, dark adaptation
Invest. Ophthalmol. Vis. Sci.. 2006; 47(12):5204-5211. https://doi.org/10.1167/iovs.05-1149

Biochemistry and Molecular Biology March 2006

Effects of Antiglaucoma Drops on MMP and TIMP Balance in Conjunctival and Subconjunctival Tissue

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Tadashi Ito; Hiroshi Ohguro; Kazuhisa Mamiya; Ikuyo Ohguro; Mitsuru Nakazawa
TAGS: antiglaucoma agents, balance, device, body tissue, conjunctiva, equilibrium, stromelysin 1, tissue inhibitor of metalloproteinases, eye, hairy-cell leukemia, hydrochloric acid
Invest. Ophthalmol. Vis. Sci.. 2006; 47(3):823-830. https://doi.org/10.1167/iovs.05-0902

Biochemistry and Molecular Biology April 2002

Preservation of Retinal Morphology and Functions in Royal College Surgeons Rat by Nilvadipine, a Ca 2+ Antagonist

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Hitoshi Yamazaki; Hiroshi Ohguro; Tadao Maeda; Ikuyo Maruyama; Yoshiko Takano; Tomomi Metoki; Mitsuru Nakazawa; Hajime Sawada; Mari Dezawa
TAGS: antagonists, language morphology, morphology, retina, surgeons, rats, crystallins, diltiazem, photoreceptors, nifedipine
Invest. Ophthalmol. Vis. Sci.. 2002; 43(4):919-926.

Immunology and Microbiology October 2001

Retinal Dysfunction in Cancer-Associated Retinopathy Is Improved by Ca 2+ Antagonist Administration and Dark Adaptation

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Hiroshi Ohguro; Kei-ichi Ogawa; Tadao Maeda; Ikuyo Maruyama; Akiko Maeda; Yoshiko Takano; Mitsuru Nakazawa
TAGS: antagonists, antibodies, cancer-associated retinopathy, dark adaptation, electroretinography, pathophysiology, rhodopsin, phosphorylation, eye, rats
Invest. Ophthalmol. Vis. Sci.. 2001; 42(11):2589-2595.

Immunology and Microbiology March 2001

Mechanisms of Photoreceptor Cell Death in Cancer-Associated Retinopathy

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Tadao Maeda; Akiko Maeda; Ikuyo Maruyama; Kei-ichi Ogawa; Yoshio Kuroki; Hiroeki Sahara; Noriyuki Sato; Hiroshi Ohguro
TAGS: antibodies, cancer-associated retinopathy, phosphorylation, photoreceptors, rhodopsin, caspase inhibitors, electroretinography, western blotting, proteins, lysate
Invest. Ophthalmol. Vis. Sci.. 2001; 42(3):705-712.

Biochemistry and Molecular Biology June 2000

Retinal Ganglion Cells Recognized by Serum Autoantibody against γ-Enolase Found in Glaucoma Patients

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Ikuyo Maruyama; Hiroshi Ohguro; Yoko Ikeda
TAGS: antibodies, autoantibodies, enolase, glaucoma, retinal ganglion cells, antigens, immunoglobulin g, electroretinography, gel, open-angle glaucoma
Invest. Ophthalmol. Vis. Sci.. 2000; 41(7):1657-1665.

Immunology and Microbiology December 1999

Cancer-Associated Retinopathy Induced by Both Anti-Recoverin and Anti-hsc70 Antibodies In Vivo

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Hiroshi Ohguro; Kei–ichi Ogawa; Tadao Maeda; Akiko Maeda; Ikuyo Maruyama
TAGS: antibodies, cancer-associated retinopathy, electroretinography
Invest. Ophthalmol. Vis. Sci.. 1999; 40(13):3160-3167.

Biochemistry and Molecular Biology November 1999

Low Expression of αA-Crystallins and Rhodopsin Kinase of Photoreceptors in Retinal Dystrophy Rat

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Akiko Maeda; Hiroshi Ohguro; Tadao Maeda; Takashi Nakagawa; Yoshio Kuroki
TAGS: crystallins, gel, phosphotransferases, photoreceptors, proteins, retinal dystrophies, rhodopsin, polymerase chain reaction, rats, sodium dodecyl sulfate-polyacrylamide gel electrophoresis
Invest. Ophthalmol. Vis. Sci.. 1999; 40(12):2788-2794.

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Omidenepag, a Selective, Prostanoid EP2 Agonist, Does Not Suppress Adipogenesis in 3D Organoids of Human Orbital Fibroblasts

Prostaglandin F2α Agonists Negatively Modulate the Size of 3D Organoids from Primary Human Orbital Fibroblasts

IκB Kinase-β Inhibitor IMD-0354 Beneficially Suppresses Retinal Vascular Permeability in Streptozotocin-Induced Diabetic Mice

Lysosomal Phospholipase A2 Activity in Pig Aqueous Humor

Fetal Check Ligament Connected between the Conjunctiva and the Medial and Lateral Recti

Identification Of Autoantibodies Against Trpm1 In Patients With Paraneoplastic Retinopathy Associated With On Bipolar Cell Dysfunction

Human Orbital Muscle: A New Point of View from the Fetal Development of Extraocular Connective Tissues

Inhibitory Effects of Retinoic Acid Receptor Alpha Stimulants on Murine Cataractogenesis through Suppression of Deregulated Calpains

Prolonged Rhodopsin Phosphorylation in Light-Induced Retinal Degeneration in Rat Models

Effects of Antiglaucoma Drops on MMP and TIMP Balance in Conjunctival and Subconjunctival Tissue

Preservation of Retinal Morphology and Functions in Royal College Surgeons Rat by Nilvadipine, a Ca 2+ Antagonist

Retinal Dysfunction in Cancer-Associated Retinopathy Is Improved by Ca 2+ Antagonist Administration and Dark Adaptation

Mechanisms of Photoreceptor Cell Death in Cancer-Associated Retinopathy

Retinal Ganglion Cells Recognized by Serum Autoantibody against γ-Enolase Found in Glaucoma Patients

Cancer-Associated Retinopathy Induced by Both Anti-Recoverin and Anti-hsc70 Antibodies In Vivo

Low Expression of αA-Crystallins and Rhodopsin Kinase of Photoreceptors in Retinal Dystrophy Rat

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