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ARVO Annual Meeting Abstract July 2018

The absense of DHHC3 affects primary and latent HSV-1 infection

Shaohui Wang; Kevin Mott; Marianne Cilluffo; Casey Kilpatrick; Shoko Murakami; Alexander V Ljubimov; Konstantin G. Kousoulas; Sita Awasthi; Bernhard Luscher; Homayon Ghiasi

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):514. doi:

ARVO Annual Meeting Abstract July 2018

Effect of recombinant HSV-1 expressing IL-4 or IFN-γ on macrophage responses in vitro and in vivo

Dhong Hyun Lee; Homayon Ghiasi

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):515. doi:

ARVO Annual Meeting Abstract June 2017

Role of CD8 + T cells versus CD8α + DCs in HSV-1 latency-reactivation

Homayon Ghiasi; Kevin R Mott; Sariah J Allen; Yasamin N Ghiasi; Harry Matundan; Terrence Town

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2986. doi:

ARVO Annual Meeting Abstract June 2017

Role of M1 and M2 macrophages in herpes simplex virus-1 infectivity in vitro and in vivo

Dhong Hyun Tony Lee; Homayon Ghiasi

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3616. doi:

ARVO Annual Meeting Abstract June 2017

Binding of HSV-1 UL20 to Golgi-specific Zinc-finger protein affect virus infectivity and latency-reactivation

Shaohui Wang; Kevin R. Mott; Kolja Wawrowsky; Bernhard Luscher; Homayon Ghiasi

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3622. doi:

ARVO Annual Meeting Abstract September 2016

Interrelationship of primary virus replication in the eye, level of latency and time to reactivate in the trigeminal ganglia (TG) of latently infected mice

Homayon Ghiasi; Kevin Mott; Sariah Allen; Yasamin Ghiasi; Terrence Town; Steven Wechsler; Harry Matundan

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2334. doi:

ARVO Annual Meeting Abstract June 2015

Mutations within the pathogenic region of HSV-1 gK signal sequences alter cell surface expression and neurovirulence

Homayon Ghiasi

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):1868. doi:

Immunology and Microbiology April 2014

Overexpression of Herpes Simplex Virus Glycoprotein K (gK) Alters Expression of HSV Receptors in Ocularly-Infected Mice

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Sariah J. Allen; Kevin R. Mott; Homayon Ghiasi
TAGS: simplexvirus, glycoprotein, eye diseases, human herpesvirus 1, mice, protein overexpression
Invest. Ophthalmol. Vis. Sci.. 2014; 55(4):2442-2451. doi: 10.1167/iovs.14-14013

ARVO Annual Meeting Abstract June 2013

Signal peptide peptidase (SPP) is required for HSV-1 infectivity through interaction with glycoprotein K (gK)

Sariah Allen; Kevin Mott; Yoshiharu Matsuura; Kohji Moriishi; Konstantin Kousoulas; Homayon Ghiasi

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):1731. doi:

ARVO Annual Meeting Abstract June 2013

The role of corneal Plasmacytoid Dendritic Cells in acute herpes simplex virus infection

Kai Hu; Deshea Harris; Takefumi Yamaguchi; Homayon Ghiasi; Ulrich von Andrian; Pedram Hamrah; Hamrah lab

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):2158. doi:

ARVO Annual Meeting Abstract March 2012

Interplay of LAT and HVEM affect HSV-1 Latency and CD8+ T Cell Exhaustion

Homayon Ghiasi; Sariah Allen; Kevin Mott; Antje Rhode-Kurnow; Xianzhi Jiang; Dale Carpenter; Clinton Jones; Steven WEchsler; Carl Ware

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):2232. doi:

ARVO Annual Meeting Abstract March 2012

Corneal Dendritic Cells Suppress Local Corneal Damage and Mediate Systemic Viral Dissemination in Herpes Simplex Keratitis

Kai Hu; Homayon Ghiasi; Ulrich H. Von Andrian; Pedram Hamrah

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):6154. doi:

ARVO Annual Meeting Abstract April 2011

The Role Of HSV-1 LAT In Enhancement Of Latency And Increase Of CD8+ T Cell Exhaustion In Trigeminal Ganglia Of Infected Mice

Homayon Ghiasi; Pedram Hamrah; Kevin Mott; Arlene Sharpe; Lbachir BenMohamed; Rafi Ahmed; Steven Wechsler; Carl Ware; Sariah Allen

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):2967. doi:

Immunology and Microbiology April 2011

Macrophage IL-12p70 Signaling Prevents HSV-1–Induced CNS Autoimmunity Triggered by Autoaggressive CD4 + Tregs

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Kevin R. Mott; David Gate; Mandana Zandian; Sariah J. Allen; Naveen Kumar Rajasagi; Nico van Rooijen; Shuang Chen; Moshe Arditi; Barry T. Rouse; Richard A. Flavell; Terrence Town; Homayon Ghiasi
TAGS: signal transduction, autoimmunity, human herpesvirus 1, macrophage, infection, mice, antigens, cd25, demyelination
Invest. Ophthalmol. Vis. Sci.. 2011; 52(5):2321-2333. doi: 10.1167/iovs.10-6536

Immunology and Microbiology July 2009

Optic Neuritis in Different Strains of Mice by a Recombinant HSV-1 Expressing Murine Interleukin-2

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Mandana Zandian; Raelene Belisle; Kevin R. Mott; Steven Nusinowitz; Florence M. Hofman; Homayon Ghiasi
TAGS: aldesleukin, human herpesvirus 1, mice, inbred balb c, optic neuritis, mice, optic nerve, demyelination
Invest. Ophthalmol. Vis. Sci.. 2009; 50(7):3275-3282. doi: 10.1167/iovs.08-3211

Immunology and Microbiology June 2009

The Role of a Glycoprotein K (gK) CD8 + T-Cell Epitope of Herpes Simplex Virus on Virus Replication and Pathogenicity

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Kevin R. Mott; Aziz A. Chentoufi; Dale Carpenter; Lbachir BenMohamed; Steven L. Wechsler; Homayon Ghiasi
TAGS: simplexvirus, glycoprotein, t-lymphocyte epitopes, human herpesvirus 1, immunization, peptides, oryctolagus cuniculus, t-lymphocyte, virus replication, infection, eye, mice, pathogenicity
Invest. Ophthalmol. Vis. Sci.. 2009; 50(6):2903-2912. doi: 10.1167/iovs.08-2957

Immunology and Microbiology December 2007

Macrophages Are Important Determinants of Acute Ocular HSV-1 Infection in Immunized Mice

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Kevin Mott; David J. Brick; Nico van Rooijen; Homayon Ghiasi
TAGS: eye infections, human herpesvirus 1, immunization, macrophage, infection, mice
Invest. Ophthalmol. Vis. Sci.. 2007; 48(12):5605-5615. doi: 10.1167/iovs.07-0894

Immunology and Microbiology May 2007

Role of Anti–Glycoproteins D (Anti–gD) and K (Anti–gK) IgGs in Pathology of Herpes Stromal Keratitis in Humans

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Kevin R. Mott; Yanira Osorio; Ezra Maguen; Anthony B. Nesburn; Alec E. Wittek; Steve Cai; Subhendra Chattopadhyay; Homayon Ghiasi
TAGS: simplexvirus, enzyme-linked immunosorbent assay, glycoprotein, grenada, human herpesvirus 1, immunoglobulin g, infection, antibodies, pathology, keratitis, stromal, serum, neutralizing antibodies
Invest. Ophthalmol. Vis. Sci.. 2007; 48(5):2185-2193. doi: 10.1167/iovs.06-1276

Immunology and Microbiology February 2004

Improved Protection from Primary Ocular HSV-1 Infection and Establishment of Latency Using Multigenic DNA Vaccines

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Yanira Osorio; Jacob Cohen; Homayon Ghiasi
TAGS: dna, human herpesvirus 1, immunization, vaccination, vaccines, dna, infection, eye, mice, proteins, viruses, neutralizing antibodies
Invest. Ophthalmol. Vis. Sci.. 2004; 45(2):506-514. doi: 10.1167/iovs.03-0828

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The absense of DHHC3 affects primary and latent HSV-1 infection

Effect of recombinant HSV-1 expressing IL-4 or IFN-γ on macrophage responses in vitro and in vivo

Role of CD8 + T cells versus CD8α + DCs in HSV-1 latency-reactivation

Role of M1 and M2 macrophages in herpes simplex virus-1 infectivity in vitro and in vivo

Binding of HSV-1 UL20 to Golgi-specific Zinc-finger protein affect virus infectivity and latency-reactivation

Interrelationship of primary virus replication in the eye, level of latency and time to reactivate in the trigeminal ganglia (TG) of latently infected mice

Mutations within the pathogenic region of HSV-1 gK signal sequences alter cell surface expression and neurovirulence

Overexpression of Herpes Simplex Virus Glycoprotein K (gK) Alters Expression of HSV Receptors in Ocularly-Infected Mice

Signal peptide peptidase (SPP) is required for HSV-1 infectivity through interaction with glycoprotein K (gK)

The role of corneal Plasmacytoid Dendritic Cells in acute herpes simplex virus infection

Interplay of LAT and HVEM affect HSV-1 Latency and CD8+ T Cell Exhaustion

Corneal Dendritic Cells Suppress Local Corneal Damage and Mediate Systemic Viral Dissemination in Herpes Simplex Keratitis

The Role Of HSV-1 LAT In Enhancement Of Latency And Increase Of CD8+ T Cell Exhaustion In Trigeminal Ganglia Of Infected Mice

Macrophage IL-12p70 Signaling Prevents HSV-1–Induced CNS Autoimmunity Triggered by Autoaggressive CD4 + Tregs

Optic Neuritis in Different Strains of Mice by a Recombinant HSV-1 Expressing Murine Interleukin-2

The Role of a Glycoprotein K (gK) CD8 + T-Cell Epitope of Herpes Simplex Virus on Virus Replication and Pathogenicity

Macrophages Are Important Determinants of Acute Ocular HSV-1 Infection in Immunized Mice

Role of Anti–Glycoproteins D (Anti–gD) and K (Anti–gK) IgGs in Pathology of Herpes Stromal Keratitis in Humans

Improved Protection from Primary Ocular HSV-1 Infection and Establishment of Latency Using Multigenic DNA Vaccines

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