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Meeting Abstract (8)
Journal Articles (3)

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Investigative Ophthalmology & Visual Science (11)

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ARVO Annual Meeting Abstract (8)
Physiology and Pharmacology (3)

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Eye Anatomy and Disorders (3)
Visual Neuroscience (1)

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oryctolagus cuniculus (3)
biological transport (2)
body tissue (2)
conjunctiva (2)
glutathione (2)
bodily secretions (1)
body fluid (1)
buffers (1)
choline (1)
conjunctival epithelial cells (1)

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ARVO Annual Meeting Abstract June 2024

Metadata analysis of Boehringer Ingelheim's opnMe database reveals the potential of BI-1942, a chymase inhibitor, for ophthalmic indications repurposing

Abbe Pingol; Hovhannes J Gukasyan; Marcus Terneus; Jessica Bramhall; Sammy Bell

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6126.

ARVO Annual Meeting Abstract June 2024

In silico simulation models for preclinical pharmacokinetic profiling in drug repositioning of a cathepsin S inhibitor for age-related dry eye

Bruno Baltazar; Marcus Terneus; Jessica Bramhall; Sammy Bell; Hovhannes J Gukasyan

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6124.

ARVO Annual Meeting Abstract June 2024

Computational Pharmaceutics: Glaucoma drug discovery and development using AutoGrow4’s genetic algorithm, ROx, ADMET Predictor, and OCAT

Andrew Levy; Hovhannes J Gukasyan

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3157.

ARVO Annual Meeting Abstract June 2024

Computational Models for Ocular Drug Repurposing of a Ribosomal S6 Kinase Inhibitor (RSKi) in Treatment of Retinal Degenerative Diseases

Lilit Mikayelyan; Marcus Terneus; Jessica Bramhall; Sammy Bell; Hovhannes J Gukasyan

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6128.

ARVO Annual Meeting Abstract June 2024

Revealing the potential of Cathepsin S inhibitor, BI-1915, for ophthalmic repurposing through the metadata analysis of Boehringer Ingelheim's opnMe database

Ethan Buriel; Marcus Terneus; Jessica Bramhall; Sammy Bell; Hovhannes J Gukasyan

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6127.

ARVO Annual Meeting Abstract June 2024

Utilization of computational methods for drug repositioning of a bradykinin 1 receptor antagonist in ocular posterior segment diseases

Tiffany Yarian; Marcus Terneus; Jessica Bramhall; Sammy Bell; Hovhannes J Gukasyan

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6125.

ARVO Annual Meeting Abstract June 2022

Ophthalmic Biopharmaceutics Classification System (oBCS): in vitro in silico relationship (IVISR) for comparability risk assessment in topical eye drop formulations

Hovhannes John Gukasyan; Xavier Faraj; Melissa Martinez; Ian S Haworth

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4169 – F0161.

ARVO Annual Meeting Abstract June 2022

Physiologically Based Dissolution Modeling for Topical Ophthalmic Suspensions

Clifford Jin; Hovhannes John Gukasyan

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4170 – F0162.

Physiology and Pharmacology October 2003

Specialized Protective Role of Mucosal Glutathione in Pigmented Rabbit Conjunctiva

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Hovhannes J. Gukasyan; Kwang-Jin Kim; Ram Kannan; Robert A. Farley; Vincent H. L. Lee
TAGS: body tissue, conjunctiva, glutathione, mucous membrane, oryctolagus cuniculus, ouabain
Invest. Ophthalmol. Vis. Sci.. 2003; 44(10):4427-4438. https://doi.org/10.1167/iovs.03-0437

Physiology and Pharmacology March 2003

Regulation of l -Cystine Transport and Intracellular GSH Level by a Nitric Oxide Donor in Primary Cultured Rabbit Conjunctival Epithelial Cell Layers

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Hovhannes J. Gukasyan; Ram Kannan; Vincent H. L. Lee; Kwang-Jin Kim
TAGS: cystine, snap-associated protein, human, biological transport, oryctolagus cuniculus, nitric oxide
Invest. Ophthalmol. Vis. Sci.. 2003; 44(3):1202-1210. https://doi.org/10.1167/iovs.02-0409

Physiology and Pharmacology April 2002

Net Glutathione Secretion across Primary Cultured Rabbit Conjunctival Epithelial Cell Layers

PDF

Hovhannes J. Gukasyan; Vincent H. L. Lee; Kwang-Jin Kim; Ram Kannan
TAGS: biological transport, bodily secretions, buffers, conjunctival epithelial cells, glutathione, mass or substance concentration per volume, oryctolagus cuniculus, sodium, conjunctiva, body tissue
Invest. Ophthalmol. Vis. Sci.. 2002; 43(4):1154-1161.

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Online ISSN: 1552-5783

Investigative Ophthalmology & Visual Science
Journal of Vision
Translational Vision Science & Technology

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