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ARVO Annual Meeting Abstract June 2021

Intravitreal HC-HA/PTX3, a soluble matrix component of amniotic membrane, inhibits proliferative vitreoretinopathy (PVR) in a mouse model of PVR

Ajay E. Kuriyan; Alison Heffer; Victor Wang; Hua He; Megha Mahabole; Steven E Feldon; Richard T Libby; Scheffer C G Tseng; Collynn Woeller

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3095. doi:

Articles February 2021

Genome-Wide Association Studies-Based Machine Learning for Prediction of Age-Related Macular Degeneration Risk

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Qi Yan; Yale Jiang; Heng Huang; Anand Swaroop; Emily Y. Chew; Daniel E. Weeks; Wei Chen; Ying Ding
TAGS: age-related macular degeneration, genome, genome-wide association study, machine learning, single nucleotide polymorphism, datasets, genotype
Trans. Vis. Sci. Tech.. 2021; 10(2):29. doi: https://doi.org/10.1167/tvst.10.2.29

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Development of HC-HA/PTX3 as a Biologic for Proliferative Vitreoretinopathy (PVR) Treatment

Hua He; Ajay E. Kuriyan; Esdras Arrieta; Megha Mahabole; Yuan Zhang; Kristy Hamlin; Victoria Graham; Jean-Marie A Parel; Harry W Flynn; Scheffer C.G. Tseng

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3061. doi:

ARVO Annual Meeting Abstract June 2020

Linear retardance of retinal amyloid deposits in Alzheimer’s disease

Melanie C W Campbell; Erik Mason; Heqing Huang; Frank Corapi; Laura Emptage; Steven Esau

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1850. doi:

ARVO Annual Meeting Abstract June 2020

Image-Guided Surgical Intervention in Vitreomacular Traction from the DISCOVER Study: Intraoperative OCT Utility, Ellipsoid Zone Dynamics, and Anatomic/Functional Outcomes

Heidi J Huang; Duriye Damla Sevgi; Sunil K Srivastava; Jamie Reese; Justis P Ehlers

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4381. doi:

Cornea March 2020

PPAR-α Agonist Fenofibrate Suppressed the Formation of Ocular Surface Squamous Metaplasia Induced by Topical Benzalkonium Chloride

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Huan He; Minghui Liang; Lan Li; Shunrong Luo; Xie Fang; Hui He; Xianwen Xiao; Huping Wu; Zhirong Lin
TAGS: fenofibrate, metaplasia, peroxisome proliferator-activated receptors, agonists, benzalkonium chloride, cornea
Invest. Ophthalmol. Vis. Sci.. 2020; 61(3):54. doi: https://doi.org/10.1167/iovs.61.3.54

ARVO Annual Meeting Abstract July 2018

Intravitreal HC-HA/PTX3: A potential novel therapy for proliferative vitreoretinopathy

Ajay E. Kuriyan; Hua He; Esdras Arrieta; Nidhi Relhan; Jeffrey Peterson; Chen-Wei Su; Megha Mahabole; Sander R Dubovy; Harry W Flynn; Jean-Marie A Parel; Scheffer C G Tseng

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1157. doi:

ARVO Annual Meeting Abstract July 2018

PPAR-α agonist Fenofibrate Suppressed the formation of ocular surface squamous metaplaisa induced by topical benzalkonium chloride

Huan He; rongrong zong; Hui He; Tong Zhou; yueping zhou; LIN Zhirong; Zuguo Liu

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3300. doi:

ARVO Annual Meeting Abstract June 2017

Deactivation of CD44-mediated Endocytosis by Heavy Chain-Hyaluronic Acid/Pentrixin3 in Human Retinal Pigment Epithelium

Hua He; Yuan Zhang; Megha Mahabole; Chen-Wei Su; Scheffer C G Tseng

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):252. doi:

ARVO Annual Meeting Abstract September 2016

A potential novel therapy for PVR: HC-HA/PTX3, an active matrix component of amniotic membrane, inhibits proliferation of rabbit RPE cells and is non-toxic intravitreally

Ajay E. Kuriyan; Hua He; Esdras A. Quintero; Nidhi Rehlan; Harry W Flynn; Chen-Wei Su; Sander R Dubovy; Jean-Marie A Parel; Scheffer C G Tseng

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1126. doi:

ARVO Annual Meeting Abstract September 2016

Senescence Mediated by p16 INK4a Impedes Reprogramming of Human Corneal Endothelial Cells into Neural Crest Progenitors

Yingting Zhu; Wen-Juan Lu; Shuangling Chen; Sean Tighe; Yuan Zhang; Chen-Wei Su; Hua He; Scheffer C G Tseng

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5277. doi:

ARVO Annual Meeting Abstract September 2016

Inhibition of Proliferation and Epithelial Mesenchymal Transition via Wnt and TGF-β Signaling Pathway in an in vitro Cell Culture Based-PVR Model by HC-HA/PTX3 Purified from Amniotic Membrane

Hua He; Ajay E. Kuriyan; Chen-Wei Su; Yuan Zhang; Megha Mahabole; Ying-Ting Zhu; Esdras A. Quintero; Nidhi Rehlan; Harry W Flynn; Jean-Marie A Parel; Scheffer C G Tseng

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5384. doi:

Biochemistry and Molecular Biology April 2016

Celecoxib and Pioglitazone as Potential Therapeutics for Regulating TGF-β–Induced Hyaluronan in Dysthyroid Myopathy

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Anny M. S. Cheng; Han Y. Yin; Angus Chen; Ya-Wen Liu; Mei-Chun Chuang; Hua He; Sean Tighe; Hosam Sheha; Shu-Lang Liao
TAGS: celecoxib, cyclooxygenase-2, cyclooxygenase-2 inhibitors, cytokine, hyaluronan, myoblasts, myopathy, pathogenesis, peroxisome proliferator-activated receptors, pioglitazone
Invest. Ophthalmol. Vis. Sci.. 2016; 57(4):1951-1959. doi: https://doi.org/10.1167/iovs.15-18018

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2015

HC-HA/PTX3, an active matrix component of amniotic membrane, inhibits proliferation and epithelial mesenchymal transition of RPE cells: a potential novel therapy for PVR

Ajay E Kuriyan; Hua He; Esdras Arrieta; Varona Sargent; Ying-Ting Zhu; Chen-Wei Su; Nidhi Batra; Harry W Flynn; Jean-Marie A Parel; Scheffer C G Tseng

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2287. doi:

ARVO Annual Meeting Abstract April 2014

Genome-wide analysis of newly developed quantitative phenotypes of astigmatism

Rui Chen; Sungeun Kim; Heng Huang; Li Shen; Jingyun Wang

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2733. doi:

Cornea March 2014

In Vivo Downregulation of Innate and Adaptive Immune Responses in Corneal Allograft Rejection by HC-HA/PTX3 Complex Purified From Amniotic Membrane

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Hua He; Yaohong Tan; Stephanie Duffort; Victor L. Perez; Scheffer C. G. Tseng
TAGS: allografting, cornea, macrophages, ptx3 protein, immune response, amnion, rejection (psychology), t-lymphocytes
Invest. Ophthalmol. Vis. Sci.. 2014; 55(3):1647-1656. doi: https://doi.org/10.1167/iovs.13-13094

Cornea September 2013

A Mouse Model of Limbal Stem Cell Deficiency Induced by Topical Medication With the Preservative Benzalkonium Chloride

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Zhirong Lin; Huan He; Tong Zhou; Xiaochen Liu; Yihui Wang; Hui He; Huping Wu; Zuguo Liu
TAGS: bacterial artificial chromosomes, benzalkonium chloride, blood alcohol concentration, bronchioloalveolar carcinoma, cornea, inflammation, limbal stem cell deficiency, mice, pharmaceutical preparations, epithelium
Invest. Ophthalmol. Vis. Sci.. 2013; 54(9):6314-6325. doi: https://doi.org/10.1167/iovs.12-10725

ARVO Annual Meeting Abstract June 2013

HC-HA Suppresses Inflammatory and Immune Responses and Improves Murine Corneal Allograft Survival

Hua He; Yaohong Tan; Victor Perez; Scheffer Tseng

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):2059. doi:

ARVO Annual Meeting Abstract June 2013

Polarization of Anti-inflammatory M2 Macrophages by HC-HA Complex Purified from Amniotic Membrane or Reconstituted In Vitro

Sean Tighe; Hua He; Suzhen Zhang; Scheffer Tseng

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):2060. doi:

ARVO Annual Meeting Abstract June 2013

HC-HA Complex Purified from Amniotic Membrane Exerts Anti-scarring Effect by Suppressing TGFβ1 but Activating TGFβ3 Signaling in Human Corneal Fibroblasts

Fu Li; Ying-Ting Zhu; Hua He; Su-Zhen Zhang; Scheffer Tseng

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):2068. doi:

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Intravitreal HC-HA/PTX3, a soluble matrix component of amniotic membrane, inhibits proliferative vitreoretinopathy (PVR) in a mouse model of PVR

Genome-Wide Association Studies-Based Machine Learning for Prediction of Age-Related Macular Degeneration Risk

Development of HC-HA/PTX3 as a Biologic for Proliferative Vitreoretinopathy (PVR) Treatment

Linear retardance of retinal amyloid deposits in Alzheimer’s disease

Image-Guided Surgical Intervention in Vitreomacular Traction from the DISCOVER Study: Intraoperative OCT Utility, Ellipsoid Zone Dynamics, and Anatomic/Functional Outcomes

PPAR-α Agonist Fenofibrate Suppressed the Formation of Ocular Surface Squamous Metaplasia Induced by Topical Benzalkonium Chloride

Intravitreal HC-HA/PTX3: A potential novel therapy for proliferative vitreoretinopathy

PPAR-α agonist Fenofibrate Suppressed the formation of ocular surface squamous metaplaisa induced by topical benzalkonium chloride

Deactivation of CD44-mediated Endocytosis by Heavy Chain-Hyaluronic Acid/Pentrixin3 in Human Retinal Pigment Epithelium

A potential novel therapy for PVR: HC-HA/PTX3, an active matrix component of amniotic membrane, inhibits proliferation of rabbit RPE cells and is non-toxic intravitreally

Senescence Mediated by p16 INK4a Impedes Reprogramming of Human Corneal Endothelial Cells into Neural Crest Progenitors

Inhibition of Proliferation and Epithelial Mesenchymal Transition via Wnt and TGF-β Signaling Pathway in an in vitro Cell Culture Based-PVR Model by HC-HA/PTX3 Purified from Amniotic Membrane

Celecoxib and Pioglitazone as Potential Therapeutics for Regulating TGF-β–Induced Hyaluronan in Dysthyroid Myopathy

HC-HA/PTX3, an active matrix component of amniotic membrane, inhibits proliferation and epithelial mesenchymal transition of RPE cells: a potential novel therapy for PVR

Genome-wide analysis of newly developed quantitative phenotypes of astigmatism

In Vivo Downregulation of Innate and Adaptive Immune Responses in Corneal Allograft Rejection by HC-HA/PTX3 Complex Purified From Amniotic Membrane

A Mouse Model of Limbal Stem Cell Deficiency Induced by Topical Medication With the Preservative Benzalkonium Chloride

HC-HA Suppresses Inflammatory and Immune Responses and Improves Murine Corneal Allograft Survival

Polarization of Anti-inflammatory M2 Macrophages by HC-HA Complex Purified from Amniotic Membrane or Reconstituted In Vitro

HC-HA Complex Purified from Amniotic Membrane Exerts Anti-scarring Effect by Suppressing TGFβ1 but Activating TGFβ3 Signaling in Human Corneal Fibroblasts

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