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Glaucoma July 2025

Exploring the Mechanisms Linking Depression and Glaucoma: A Cohort Study of UK Biobank

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Xueming Yao; Yuhan Jiang; Hongxi Yang; Ju Guo; Xiaohong Wang; Andrzej Grzybowski; Mulin Jun Li; Hua Yan
TAGS: depressive disorders, glaucoma, cohort studies, uk biobank, genetics
Trans. Vis. Sci. Tech.. 2025; 14(7):5. https://doi.org/10.1167/tvst.14.7.5

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2025

A normative cone photoreceptor database study using Adaptive Optics Scanning Light Ophthalmoscopy: insights from the Chinese population.

Weixiao Fan; Ji Ren; Yuan Zong; Jiaojiao Wei; Jiajie Zhao; Yuanyuan Liu; Xiaohan Wu; Haochen Wang; Jianchong Li; Chuanzhen Zheng; Tao Cai; Xiying Mao; Na Su; Nianfeng Tang; Tianyu Mao; Jianfeng Luo; Songtao Yuan; Yong Zeng; Wei Zhou; Chunhui Jiang; Qinghuai Liu; Zhengzheng Wu; Hua Yan; Xinghuai Sun; Jie Zhang

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1009.

ARVO Annual Meeting Abstract June 2025

Astigmatism Reduces the Accuracy of Artificial Intelligence-Predictions for Axial Elongation in School-Age Children

Dong LIANG; Tsz Wing Leung; Bei Du; Zhengji LIU; Hua Yan; Ruihua Wei; Chea-Su Kee

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):3846.

Biochemistry and Molecular Biology June 2025

Three-Dimensional Culture of Orbital Fibroblasts From Thyroid Eye Disease Induce In Vivo-Like Tissue Remodeling and Fibrosis

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Xiaoli Bao; Zhihui Xu; Xi Wang; Te Zhang; Huijing Ye; Huasheng Yang
TAGS: body tissue, fibroblasts, fibrosis, graves' ophthalmopathy, tissue remodeling, spheroids, cellular, genes, polymerase chain reaction
Invest. Ophthalmol. Vis. Sci.. 2025; 66(6):67. https://doi.org/10.1167/iovs.66.6.67

Includes: Supplemental Content

Cornea June 2025

HIF-1α Promotes Inflammatory Responses in Aspergillus Fumigatus Keratitis by Activating Pyroptosis Through Caspase-8/GSDMD Pathway

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Hua Yang; Mengzhu Liu; Shiqi Song; Qiang Xu; Jieun Lee; Jintao Sun; Shasha Xue; Xiaoyan Sun; Chengye Che
TAGS: aspergillus fumigatus, caspase-8, cornea, inflammatory response, keratitis, macrophages, mice, pyroptosis, infections, proteins
Invest. Ophthalmol. Vis. Sci.. 2025; 66(6):32. https://doi.org/10.1167/iovs.66.6.32

Biochemistry and Molecular Biology May 2025

Canonical and Truncated Transglutaminase-2 Drive TGF-β1 Autocrine Loop to Induce Fibrosis in Graves’ Orbitopathy

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Xiaoli Bao; Zhihui Xu; Xi Wang; Te Zhang; Xiaotong Sha; Anqi Sun; Huijing Ye; Huasheng Yang
TAGS: fibrosis, protein glutamine gamma glutamyltransferase 2, autocrine, genes
Invest. Ophthalmol. Vis. Sci.. 2025; 66(5):22. https://doi.org/10.1167/iovs.66.5.22

Includes: Supplemental Content

Retina February 2025

Association Between Hormone Levels and Retinopathy in Patients With Type 2 Diabetes: A Cross-Sectional Study

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Yu Meng; Xueli Yang; Yuxin Fan; Ming Liu; Fengqi Zhou; Qihua Wang; Yuezhu Lu; Yun Zhu; Hua Yan
TAGS: diabetes mellitus, type 2, gonadal hormones, hormones, retinal diseases, testosterone
Trans. Vis. Sci. Tech.. 2025; 14(2):17. https://doi.org/10.1167/tvst.14.2.17

Includes: Supplemental Content

Anatomy and Pathology/Oncology January 2025

Metabolic Atlas of Human Eyelid Infiltrative Basal Cell Carcinoma

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Yanjing Huang; Chengjie He; Qiuling Hu; Zhong Liu; Xingyi Li; Wuyou Gao; Xuanwei Liang; Rongxin Chen; Zhen Mao; Xianchai Lin
TAGS: basal cell carcinoma, eyelid, genes, infiltrative basal cell carcinoma, metabolites, neoplasms, metabolic disturbance, tumor microenvironment, up-regulation (physiology), spectrometry, mass, matrix-assisted laser desorption-ionization
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):11. https://doi.org/10.1167/iovs.66.1.11

Includes: Supplemental Content

Cornea November 2024

cRGD-Conjugated Bilirubin Nanoparticles Alleviate Dry Eye Disease Via Activating the PINK1-Mediated Mitophagy

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Yang Huang; Lijun Wang; Haiying Jin
TAGS: bilirubin, cornea, dry eye syndromes, mice, mitophagy, nadph oxidase 4, nanoparticles, ocular surfaces, pink1 gene, nitric oxide synthase
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):55. https://doi.org/10.1167/iovs.65.13.55

Includes: Supplemental Content

Clinical and Epidemiologic Research November 2024

Impact of Astigmatism on Axial Elongation in School-Age Children: A Five-Year Population-Based Study in Tianjin, China

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Dong Liang; Bei Du; Tsz-Wing Leung; Zhuzhu Liu; Qiang Su; Nan Jin; Ziyu Zhang; Mingguang He; Hua Yan; Ruihua Wei; Chea-Su Kee
TAGS: astigmatism, refractive errors
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):45. https://doi.org/10.1167/iovs.65.13.45

Includes: Supplemental Content

Retinal Cell Biology November 2024

Single-Cell Multiomics Profiling Reveals Heterogeneity of Müller Cells in the Oxygen-Induced Retinopathy Model

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Xueming Yao; Ziqi Li; Yi Lei; Qiangyun Liu; Siyue Chen; Haokun Zhang; Xue Dong; Kai He; Ju Guo; Mulin Jun Li; Xiaohong Wang; Hua Yan
TAGS: astrocytes, genes, heterogeneity, mice, multiomics, oxygen, retinal diseases, small nuclear rna, cell communication, retina
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):8. https://doi.org/10.1167/iovs.65.13.8

Includes: Supplemental Content

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology July 2024

Deficits of the “Good” Eye in Amblyopia: Processing Geometric Properties

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Minjuan Zhu; Jianhui Liang; Wenbo Wang; Hongwei Deng; Yan Huang
TAGS: amblyopia, eye
Invest. Ophthalmol. Vis. Sci.. 2024; 65(8):33. https://doi.org/10.1167/iovs.65.8.33

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Bruton's tyrosine kinase inhibition suppresses pathological retinal angiogenesis

Siyue Chen; Xiaohong Wang; Qiang Liu; Hua Yan

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):298.

ARVO Annual Meeting Abstract June 2024

Smoking aggravates neovascular age-related macular degeneration via Sema4D-PlexinB1 axis-mediated activation of pericytes

Kai He; Xue Dong; Tianjing Yang; Ziqi Li; Xiaohong Wang; Hua Yan

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4996.

ARVO Annual Meeting Abstract June 2024

Observation of changes of photoreceptor on macular hole closure types surgery using adaptive optics combined with optical coherence tomography and microperimetry

Hua Yan; Yuanyuan Liu; Jinguo Yu; Song Chen; Tiangeng He

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3120.

ARVO Annual Meeting Abstract June 2024

Multi-omics profiling of retinal pigment epithelium reveals enhancer-driven activation of RANK-NFATc1 signaling in traumatic proliferative vitreoretinopathy

Mengyu Liao; Xiaohong Wang; Yupeng Chen; Hua Yan

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):657.

ARVO Annual Meeting Abstract June 2024

Complement Factor D Expression in Normal and Age-Related Macular Degeneration Human Eyes

Aixu Sun; Hua Yang; Ying Hu; Jingtai Cao; Botir T Sagdullaev

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):559.

ARVO Annual Meeting Abstract June 2024

Differential Analysis of Complement Expression and Localization Between Mouse, Rat, and Human Eyes

Aarin D Jones; Hua Yang; Aixu Sun; Guillermo Lehmann; Wen Fury; Ying Hu; Botir T Sagdullaev

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):558.

ARVO Annual Meeting Abstract June 2024

Empowering universal self-screening for malignant ocular rare tumors using smartphones

Ruixin Wang; Duoru Lin; Shaowei Bi; Mingyuan Li; Huasheng Yang; Haotian Lin

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1604.

ARVO Annual Meeting Abstract June 2024

Progranulin-Deficient Mouse: A Valuable Model for GRN-related Eye Disorders

Hua Yang; ming yuan; Rajeev Wudali; Adrianna Latuszek; Henry Chen; Jacob Treinish; Ying Hu; Susan D. Croll; Botir T Sagdullaev

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4754.

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Exploring the Mechanisms Linking Depression and Glaucoma: A Cohort Study of UK Biobank

A normative cone photoreceptor database study using Adaptive Optics Scanning Light Ophthalmoscopy: insights from the Chinese population.

Astigmatism Reduces the Accuracy of Artificial Intelligence-Predictions for Axial Elongation in School-Age Children

Three-Dimensional Culture of Orbital Fibroblasts From Thyroid Eye Disease Induce In Vivo-Like Tissue Remodeling and Fibrosis

HIF-1α Promotes Inflammatory Responses in Aspergillus Fumigatus Keratitis by Activating Pyroptosis Through Caspase-8/GSDMD Pathway

Canonical and Truncated Transglutaminase-2 Drive TGF-β1 Autocrine Loop to Induce Fibrosis in Graves’ Orbitopathy

Association Between Hormone Levels and Retinopathy in Patients With Type 2 Diabetes: A Cross-Sectional Study

Metabolic Atlas of Human Eyelid Infiltrative Basal Cell Carcinoma

cRGD-Conjugated Bilirubin Nanoparticles Alleviate Dry Eye Disease Via Activating the PINK1-Mediated Mitophagy

Impact of Astigmatism on Axial Elongation in School-Age Children: A Five-Year Population-Based Study in Tianjin, China

Single-Cell Multiomics Profiling Reveals Heterogeneity of Müller Cells in the Oxygen-Induced Retinopathy Model

Deficits of the “Good” Eye in Amblyopia: Processing Geometric Properties

Bruton's tyrosine kinase inhibition suppresses pathological retinal angiogenesis

Smoking aggravates neovascular age-related macular degeneration via Sema4D-PlexinB1 axis-mediated activation of pericytes

Observation of changes of photoreceptor on macular hole closure types surgery using adaptive optics combined with optical coherence tomography and microperimetry

Multi-omics profiling of retinal pigment epithelium reveals enhancer-driven activation of RANK-NFATc1 signaling in traumatic proliferative vitreoretinopathy

Complement Factor D Expression in Normal and Age-Related Macular Degeneration Human Eyes

Differential Analysis of Complement Expression and Localization Between Mouse, Rat, and Human Eyes

Empowering universal self-screening for malignant ocular rare tumors using smartphones

Progranulin-Deficient Mouse: A Valuable Model for GRN-related Eye Disorders

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