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Lens April 2025

Macrophage-Hosted Porphyromonas gingivalis Is a Risk Factor for Cataract Development

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Dongzhe Zhang; Junwei Qu; Cuncun Ke; Xiumei Kong; Mengyun Liu; Iqbal Nawaz Khan; Shuxin Huang; Haijiao Tian; Tong Xie; Ke Qiu; Jing Li; Mingli Wang; Hui Li; Fengling Yuan; Weikai Guo; Mingya Cao; Jing Zhang; Keke Zhu; Jin Luo; Fengyan Zhang; Xiukun Cui; Hongmei Mu; Yanzhong Hu
TAGS: body tissue, cataract, epithelium, infections, lens (device), macrophages, risk factors, porphyromonas gingivalis, hypertension, lens, crystalline
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):68. https://doi.org/10.1167/iovs.66.4.68

Includes: Supplemental Content

Retina April 2025

Use of SGLT2 Inhibitors Versus DPP-4 Inhibitors and Age-Related Macular Degeneration in Patients WithType 2 Diabetes: A Multinational Cohort Study

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Ssu-Yu Pan; Chien-Hsiang Weng; Shang-Feng Tsai; Hui-Ju Lin; Jun-Fu Lin; Ching-Heng Lin; I-Jong Wang; Chien-Chih Chou
TAGS: age-related macular degeneration, diabetes mellitus, type 2, dipeptidyl-peptidase iv inhibitors, sodium-glucose transporter 2 inhibitors, diabetes mellitus, cohort studies
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):58. https://doi.org/10.1167/iovs.66.4.58

Includes: Supplemental Content

Retina April 2025

A Novel AAV Capsid-Mediated RS1 Gene Therapy Restored Retinal Function to Wild-Type Levels in Rs1 R213W Mouse Model

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Xing Wei; Sisi Ma; Yunyu Zhou; Haoliang Cui; Shan Zhang; Duanyang Wang; Yingying Fu; Wei Li; Huihui Han; Yamei Li; Wuyi Li; Huixin Liu; Zixi Sun; Xiaoxu Han; Xuan Zou; Hui Li; Cheng Wang; Ruifang Sui
TAGS: electroretinography, mice, gene therapy, capsid
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):37. https://doi.org/10.1167/iovs.66.4.37

Includes: Supplemental Content

Uveitis April 2025

Identification of Subtypes of Herpetic Anterior Uveitis and Characterization of Their Clinical Features and Visual Outcome in a Chinese Population

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Hui Liu; Suo Guo; Yaning Liu; Guannan Su; Peizeng Yang
TAGS: chinese (other dialects), signs and symptoms, uveitis, anterior, chinese people, cytomegalovirus, intraocular pressure
Trans. Vis. Sci. Tech.. 2025; 14(4):2. https://doi.org/10.1167/tvst.14.4.2

Includes: Supplemental Content

Cornea March 2025

Isolated Mitochondrial Transplantation as a Novel Treatment for Corneal Chemical Burns

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Dan Jiang; Jinjie Yu; Xiaoqing Wu; Xintong Yu; Pinyan Jin; Huikang Zheng; Huiru Liu; Wei Xu; Qizhou Lian; Wei Chen
TAGS: mitochondria, cornea, transplantation, mice, chemical burns
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):14. https://doi.org/10.1167/iovs.66.3.14

Includes: Multimedia, Supplemental Content

Retina December 2024

Retinal Neurovascular Impairment in Full-Course Diabetic Retinopathy: The Guangdong Diabetic Retinopathy Multiple-Omics Study

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Chunran Lai; Ting Su; Jiahui Cao; Qinyi Li; Zijing Du; Yaxin Wang; Shan Wang; Qiaowei Wu; Yijun Hu; Ying Fang; Huiyi Liao; Zhuoting Zhu; Xianwen Shang; Mingguang He; Honghua Yu; Xiayin Zhang
TAGS: diabetes mellitus, type 2, diabetic retinopathy, electroretinography, nonproliferative diabetic retinopathy, peripheral neurovascular compromise, photopsia, retinal cone, optical coherence tomography, retina, photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):20. https://doi.org/10.1167/iovs.65.14.20

Includes: Supplemental Content

Vision Sciences Society Annual Meeting Abstract September 2024

Like adults, children cannot distinguish between AI-synthesized faces from real ones but exhibit a response bias toward synthesized faces

Sarina Hui-Lin Chien; Pei-Tzu Liu; Yu-Ting Ma; Chien-Kai Chang

Journal of Vision. 2024; 24(10):844. https://doi.org/10.1167/jov.24.10.844

Retinal Cell Biology June 2024

Shootin1 Regulates Retinal Ganglion Cell Neurite Development: Insights From an RGC Direct Somatic Cell Reprogramming Model

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Ke Zhang; Tingting Zhang; Qinghai He; Huilin Liang; Jingyi Guo; Mingbing Zeng; Shuyi Chen
TAGS: neurites, retinal ganglion cells, somatic cell, axon, neurons
Invest. Ophthalmol. Vis. Sci.. 2024; 65(6):41. https://doi.org/10.1167/iovs.65.6.41

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Classifying Mouse RPE Morphometric Heterogeneity Using REShAPE – an AI-based Image Analysis Tool

Dylan Walmsley; Dominik Reichert; Huirong Li; Kapil Bharti; ruchi Fnu; Davide Ortolan

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):363.

ARVO Annual Meeting Abstract June 2024

Epidemiologic Characteristics of Dry Eye Disease (DED) Treatment in South Korea: A Nationwide Population-based Study

Jiu Lee; Joon Bo Lee; Won Seok Song; Yeo Kyoung Won; Dong Hui Lim

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2857.

ARVO Annual Meeting Abstract June 2024

An RPE subpopulation is resistant to oxidative-induced inflammation through SERPINE3-Caspase1 pathway

Huirong Li; Wei Yan; David McGaughey; Temesgen D Fufa; Lijin Dong; Tiansen Li; Suja Hiriyanna; Bin Guan; Koray Dogan Kaya; Ashley M Rasys; James Liu; Takerra Johnson; Jiwon Ryu; Brian P Brooks; Robert B Hufnagel

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2184.

ARVO Annual Meeting Abstract June 2024

Classification of Bacterial Keratitis Activity with Patch-Based Deep Learning using Three Anterior Segment Images

HeeJee Yun; Yeo Kyoung Won; Sung Ho Jung; Won Seok Song; Ju Hwan Lee; Hakje Yoo; Dong Hui Lim

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1581.

Genetics April 2024

Longitudinal Natural History Study of Visual Function in Bietti Crystalline Dystrophy: Implications for Early Intervention

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Xiaoxu Han; Huajin Li; Dingding Zhang; Hui Li; Xuan Zou; Ruifang Sui
TAGS: crystal structure, early intervention (education), natural history, vision, linear regression
Invest. Ophthalmol. Vis. Sci.. 2024; 65(4):25. https://doi.org/10.1167/iovs.65.4.25

Genetics February 2024

Genotype–Phenotype Associations in an X-Linked Retinoschisis Patient Cohort: The Molecular Dynamic Insight and a Promising SD-OCT Indicator

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Xing Wei; Hui Li; Tian Zhu; Zixi Sun; Ruifang Sui
TAGS: cohort studies, cysts, genotype, genotype-phenotype associations, proteins, spectral domain-optical coherence tomography, x-linked retinoschisis, phenotype, cutaneous collagenous vasculopathy, electroretinography
Invest. Ophthalmol. Vis. Sci.. 2024; 65(2):17. https://doi.org/10.1167/iovs.65.2.17

Includes: Supplemental Content

Retina February 2024

Central and Peripheral Changes in Retinal Vein Occlusion and Fellow Eyes in Ultra-Widefield Optical Coherence Tomography Angiography

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Xin-yu Zhao; Qing Zhao; Chu-ting Wang; Li-hui Meng; Shi-yu Cheng; Xing-wang Gu; Srinivas R. Sadda; You-xin Chen
TAGS: angiogram, central retinal vein occlusion, eye, ischemia, optical coherence tomography, retinal vein occlusion, visual field defects, cortical blindness, cardiovascular imaging
Invest. Ophthalmol. Vis. Sci.. 2024; 65(2):6. https://doi.org/10.1167/iovs.65.2.6

Genetics January 2024

Distinct Clinical Effects of Two RP1L1 Hotspots in East Asian Patients With Occult Macular Dystrophy (Miyake Disease): EAOMD Report 4

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Yu Fujinami-Yokokawa; Kwangsic Joo; Xiao Liu; Kazushige Tsunoda; Mineo Kondo; Seong Joon Ahn; Anthony G. Robson; Izumi Naka; Jun Ohashi; Hui Li; Lizhu Yang; Gavin Arno; Nikolas Pontikos; Kyu Hyung Park; Michel Michaelides; Hisateru Tachimori; Hiroaki Miyata; Ruifang Sui; Se Joon Woo; Kaoru Fujinami; for the East Asia Inherited Retinal Disease Society Study Group*
TAGS: east asian people, genotype, macular dystrophy, spectral domain-optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2024; 65(1):41. https://doi.org/10.1167/iovs.65.1.41

Includes: Supplemental Content

Retina January 2024

Response of Human Retinal Microvascular Endothelial Cells to Influenza A (H1N1) Infection and the Underlying Molecular Mechanism

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Shuo Yang; Zixin Fan; Xiaofeng Lu; Hui Liu; Ziying Zhou; Hui Qi; Jian Zeng; Mianying Zheng; Xuan Zou; Shisong Fang; Guoming Zhang
TAGS: infections, influenza a virus, h1n1 subtype, swine influenza, endothelial cells
Invest. Ophthalmol. Vis. Sci.. 2024; 65(1):38. https://doi.org/10.1167/iovs.65.1.38

Vision Sciences Society Annual Meeting Abstract August 2023

Mixed-race categorization of Asian-White and Asain-Black faces in Taiwanese children and adults: effect of skin color revealed by a 3AFC task

Sarina Hui-Lin Chien; Chien-Kai Chang; Evelyn Hsin-Yi Tsai; I-Fan Lin

Journal of Vision. 2023; 23(9):5275. https://doi.org/10.1167/jov.23.9.5275

Clinical and Epidemiologic Research July 2023

Diabetes-Related Risk Factors for Exudative Age-Related Macular Degeneration: A Nationwide Cohort Study of a Diabetic Population

PDF

Sungsoon Hwang; Se Woong Kang; Sang Jin Kim; Kyu Na Lee; Kyungdo Han; Dong Hui Lim
TAGS: cohort studies, diabetes mellitus, diabetes mellitus, type 2, exudative age-related macular degeneration, risk factors
Invest. Ophthalmol. Vis. Sci.. 2023; 64(10):10. https://doi.org/10.1167/iovs.64.10.10

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

Genotype-phenotype associations in an X-linked retinoschisis patient cohort: the molecular dynamic insight and a promising SD-OCT indicator

Xing Wei; Hui Li; Tian Zhu; Ruifang Sui

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1556.

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Macrophage-Hosted Porphyromonas gingivalis Is a Risk Factor for Cataract Development

Use of SGLT2 Inhibitors Versus DPP-4 Inhibitors and Age-Related Macular Degeneration in Patients WithType 2 Diabetes: A Multinational Cohort Study

A Novel AAV Capsid-Mediated RS1 Gene Therapy Restored Retinal Function to Wild-Type Levels in Rs1 R213W Mouse Model

Identification of Subtypes of Herpetic Anterior Uveitis and Characterization of Their Clinical Features and Visual Outcome in a Chinese Population

Isolated Mitochondrial Transplantation as a Novel Treatment for Corneal Chemical Burns

Retinal Neurovascular Impairment in Full-Course Diabetic Retinopathy: The Guangdong Diabetic Retinopathy Multiple-Omics Study

Like adults, children cannot distinguish between AI-synthesized faces from real ones but exhibit a response bias toward synthesized faces

Shootin1 Regulates Retinal Ganglion Cell Neurite Development: Insights From an RGC Direct Somatic Cell Reprogramming Model

Classifying Mouse RPE Morphometric Heterogeneity Using REShAPE – an AI-based Image Analysis Tool

Epidemiologic Characteristics of Dry Eye Disease (DED) Treatment in South Korea: A Nationwide Population-based Study

An RPE subpopulation is resistant to oxidative-induced inflammation through SERPINE3-Caspase1 pathway

Classification of Bacterial Keratitis Activity with Patch-Based Deep Learning using Three Anterior Segment Images

Longitudinal Natural History Study of Visual Function in Bietti Crystalline Dystrophy: Implications for Early Intervention

Genotype–Phenotype Associations in an X-Linked Retinoschisis Patient Cohort: The Molecular Dynamic Insight and a Promising SD-OCT Indicator

Central and Peripheral Changes in Retinal Vein Occlusion and Fellow Eyes in Ultra-Widefield Optical Coherence Tomography Angiography

Distinct Clinical Effects of Two RP1L1 Hotspots in East Asian Patients With Occult Macular Dystrophy (Miyake Disease): EAOMD Report 4

Response of Human Retinal Microvascular Endothelial Cells to Influenza A (H1N1) Infection and the Underlying Molecular Mechanism

Mixed-race categorization of Asian-White and Asain-Black faces in Taiwanese children and adults: effect of skin color revealed by a 3AFC task

Diabetes-Related Risk Factors for Exudative Age-Related Macular Degeneration: A Nationwide Cohort Study of a Diabetic Population

Genotype-phenotype associations in an X-linked retinoschisis patient cohort: the molecular dynamic insight and a promising SD-OCT indicator

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