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New Developments in Vision Research October 2021

The Intraocular Pressure Lowering Effect of a Dual Kinase Inhibitor (ITRI-E-(S)4046) in Ocular Hypertensive Animal Models

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Yi-Hsun Chen; Wan-Ying Lin; Yu Chuan Huang; Wan Yu Ho; Chih-Wei Fu; Chia-Mu Tu; Chrong-Shiong Hwang; Chiu-Lien Hung; Ming-Chun Lin; Felice Cheng; Yen-Jen Wang; Chih-Hung Chen; Shuen-Hsiang Chou; Meng-Ping She; Chia-Yi Yang; Hui-Ling Cheng; Chih-Peng Liu; Da-Wen Lu
TAGS: animal model, intraocular pressure, kinase inhibitors, ocular hypertension, oryctolagus cuniculus, phosphotransferases
Invest. Ophthalmol. Vis. Sci.. 2021; 62(13):12. doi: https://doi.org/10.1167/iovs.62.13.12

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2021

Long-term Survival of Cultivated Oral Mucosal Epithelial Cell Sheets in post-COMET Patients

Yi-Jen Hsueh; Hung-Chi Chen; Hui-Kang David Ma

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):855. doi:

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology May 2021

Inhibition of Retinal Ganglion Cell Loss By a Novel ROCK Inhibitor (E212) in Ischemic Optic Nerve Injury Via Antioxidative and Anti-Inflammatory Actions

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Yao-Tseng Wen; Ching-Wen Huang; Chih-Peng Liu; Chih-Hung Chen; Chia-Mu Tu; Chrong-Shiong Hwang; Yi-Hsun Chen; Wan-Ru Chen; Keh-Liang Lin; Yu-Chieh Ho; Ta-Ching Chen; Rong-Kung Tsai
TAGS: anti-inflammatory agents, infarction, ischemia, neuroprotective effect, optic nerve injuries, painful bladder syndrome, retina, retinal ganglion cells, macrophages, fluoro-gold
Invest. Ophthalmol. Vis. Sci.. 2021; 62(6):21. doi: https://doi.org/10.1167/iovs.62.6.21

Includes: Supplemental Content

Articles July 2020

Filamentous Fungal Keratitis in Taiwan: Based on Molecular Diagnosis

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Ning Hung; Lung-Kun Yeh; David Hui-Kang Ma; Hsin-Chiung Lin; Hsin-Yuan Tan; Hung-Chi Chen; Pei-Lun Sun; Ching-Hsi Hsiao
TAGS: fungal keratitis, molecular diagnostic techniques, taiwan, disease susceptibility
Trans. Vis. Sci. Tech.. 2020; 9(8):32. doi: https://doi.org/10.1167/tvst.9.8.32

ARVO Annual Meeting Abstract June 2020

Lysophosphatidic-acid treatment of tissue-cultivated corneas increases endothelial density by stimulating stromal IL-1β secretion

Hung-Chi Chen; Yi-Jen Hsueh; Yaa-Jyuhn James Meir; Chieh-Cheng Huang; Tsai-Te Lu; Chao-Min Cheng; Wei-Chi Wu

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1445. doi:

Cornea March 2020

Corneal Sensitivity and Tear Function in Recurrent Corneal Erosion Syndrome

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Eugene Yu-Chuan Kang; Hung-Ta Chen; Yi-Jen Hsueh; Hung-Chi Chen; Hsin-Yuan Tan; Ching-Hsi Hsiao; Lung-Kun Yeh; Wei-Chi Wu
TAGS: cornea, eye, recurrent erosion of cornea, syndrome, schirmer tear test procedure
Invest. Ophthalmol. Vis. Sci.. 2020; 61(3):21. doi: https://doi.org/10.1167/iovs.61.3.21

Articles May 2019

Extracellular Matrix Protein Coating of Processed Fish Scales Improves Human Corneal Endothelial Cell Adhesion and Proliferation

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Yi-Jen Hsueh; David Hui-Kang Ma; Kathleen Sheng-Chuan Ma; Tze-Kai Wang; Cheng-Hung Chou; Chien-Cheng Lin; Min-Chang Huang; Li-Jyuan Luo; Jui-Yang Lai; Hung-Chi Chen
TAGS: adhesions, cornea, endothelial cells, extracellular matrix proteins, proteins, weight measurement scales, cell proliferation
Trans. Vis. Sci. Tech.. 2019; 8(3):27. doi: https://doi.org/10.1167/tvst.8.3.27

Includes: Supplemental Content

Glaucoma February 2019

A Highly Selective Rho-Kinase Inhibitor (ITRI-E-212) Potentially Treats Glaucoma Upon Topical Administration With Low Incidence of Ocular Hyperemia

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Cherng-Ru Hsu; Yi-Hsun Chen; Chih-Peng Liu; Chih-Hung Chen; Kuo-Kuei Huang; Jui-Wen Huang; Meng-Nan Lin; Chih-Lung Lin; Wan-Ru Chen; Yi-Ling Hsu; Tze-chung Lee; Shuen-Hsiang Chou; Chia-Mu Tu; Chrong-Shiong Hwang; Yu Chuan Huang; Da-Wen Lu
TAGS: administration, topical, erythema, glaucoma, hypertension, intraocular pressure, oryctolagus cuniculus, phosphotransferases, conjunctival injection, incidence
Invest. Ophthalmol. Vis. Sci.. 2019; 60(2):624-633. doi: https://doi.org/10.1167/iovs.18-25252

Clinical and Epidemiologic Research October 2018

Effect of Uveitis on the Development of Keratopathy: A Population-Based Cohort Study

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Chan-Wei Nien; Chia-Yi Lee; Shih-Chun Chao; Hung-Jui Hsu; Jing-Yang Huang; Chao-Bin Yeh; Hung-Chi Chen; Chi-Chin Sun; Hung-Yu Lin; Shun-Fa Yang
TAGS: cohort studies, uveitis
Invest. Ophthalmol. Vis. Sci.. 2018; 59(12):5053-5059. doi: https://doi.org/10.1167/iovs.18-25039

ARVO Annual Meeting Abstract July 2018

Proliferation of corneal epithelial cells is regulated by p63/ATF3 related pathway

Yi-Jen Hsueh; Hung-Chi Chen; Tze-Kai Wang; Kuo-Hsuan Chien; David Hui-Kang Ma

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3845. doi:

ARVO Annual Meeting Abstract July 2018

ECM Protein Coating on Tilapia Fish Scales Improves HCEC Adhesion and Proliferation Through ILK/p63 Signaling

David Hui-Kang Ma; Yi-Jen Hsueh; Hung-Chi Chen; Jui-Yang Lai; Kathleen Sheng-Chuan Ma

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1379. doi:

ARVO Annual Meeting Abstract September 2016

Suppression of Hippo pathway in a novel proliferative corneal organ culture system

Hung-Chi Chen; Yi-Jen Hsueh; Tze-Kai Wang; Sung-En Wu; David Hui-Kang Ma; Jan-Kan Chen

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5312. doi:

ARVO Annual Meeting Abstract September 2016

Epithelial progenitors are preserved in collagenase-digested oral mucosa

Yi-Jen Hsueh; Hung-Chi Chen; David Hui-Kang Ma

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5314. doi:

ARVO Annual Meeting Abstract June 2015

Nuclear YAP - promoted proliferation can be induced by lysophosphatidic acid via the PI3K and ROCK pathway s in contact-inhibited human corneal endothelial cells

Yi-Jen Hsueh; Hung-Chi Chen; Sung-En Wu; Tze-Kai Wang; Jan-Kan Chen; David Hui-Kang Ma

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):1142. doi:

ARVO Annual Meeting Abstract June 2015

Corneal Sensitivity and Tear Functions in Patients with Recurrent Corneal Erosion Syndrome

Hung-Chi Chen; Yi-Jen Hsueh; Sung-En Wu; Tze-Kai Wang; David Hui-Kang Ma; Jan-Kan Chen

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):715. doi:

ARVO Annual Meeting Abstract April 2014

Stem/progenitor properties are preserved during ex vivo expansion of human oral mucosal epithelial cell sheet by collagenase but not dispase

Hung-Chi Chen; David Hui-Kang Ma; Hsiang-Fu Huang; Jesseica Ma; Yi-Jen Hsueh

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1444. doi:

ARVO Annual Meeting Abstract April 2014

Proliferation induced by lysophosphatidic acid via Hippo-YAP pathway in contact-inhibited human corneal endothelial cells

Yi-Jen Hsueh; Hung-Chi Chen; Sung-En Wu; Jan-Kan Chen; David Hui-Kang Ma

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2041. doi:

ARVO Annual Meeting Abstract June 2013

Relationships of meibomian gland dysfunction and cardiovascular disease risk factors in a middle-aged population

Hung-Chi Chen; Chien-Ting Chen; Hung-Ta Chen; Yih-Shiou Hwang; Hsin-Chiung Lin; David Ma

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):5431. doi:

ARVO Annual Meeting Abstract June 2013

EDC/NHS cross-linked amniotic membrane preferentially preserves corneal epithelial progenitor cells by activating Wnt/β catenin signaling

David Ma; Hung-Chi Chen; Jui-Yang Lai; Kevin Ma; Lung-Kun Yeh; Unique Yang; Jessica Ma

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):1002. doi:

Cornea August 2012

Expression of Angiogenesis-Related Factors in Human Corneas after Cultivated Oral Mucosal Epithelial Transplantation

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Hung-Chi Jesse Chen; Lung-Kun Yeh; Yueh-Ju Tsai; Chyong-Huey Lai; Chi-Chun Chen; Jui-Yang Lai; Chi-Chin Sun; Grace Chang; Tsann-Long Hwang; Jan-Kan Chen; David Hui-Kang Ma
TAGS: angiogenesis, angiogenesis factor, cornea, epithelium, oral mucous membrane, transplantation, angiogenesis inhibitors, conjunctiva, thrombospondin 1
Invest. Ophthalmol. Vis. Sci.. 2012; 53(9):5615-5623. doi: https://doi.org/10.1167/iovs.11-9293

Includes: Supplemental Content

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The Intraocular Pressure Lowering Effect of a Dual Kinase Inhibitor (ITRI-E-(S)4046) in Ocular Hypertensive Animal Models

Long-term Survival of Cultivated Oral Mucosal Epithelial Cell Sheets in post-COMET Patients

Inhibition of Retinal Ganglion Cell Loss By a Novel ROCK Inhibitor (E212) in Ischemic Optic Nerve Injury Via Antioxidative and Anti-Inflammatory Actions

Filamentous Fungal Keratitis in Taiwan: Based on Molecular Diagnosis

Lysophosphatidic-acid treatment of tissue-cultivated corneas increases endothelial density by stimulating stromal IL-1β secretion

Corneal Sensitivity and Tear Function in Recurrent Corneal Erosion Syndrome

Extracellular Matrix Protein Coating of Processed Fish Scales Improves Human Corneal Endothelial Cell Adhesion and Proliferation

A Highly Selective Rho-Kinase Inhibitor (ITRI-E-212) Potentially Treats Glaucoma Upon Topical Administration With Low Incidence of Ocular Hyperemia

Effect of Uveitis on the Development of Keratopathy: A Population-Based Cohort Study

Proliferation of corneal epithelial cells is regulated by p63/ATF3 related pathway

ECM Protein Coating on Tilapia Fish Scales Improves HCEC Adhesion and Proliferation Through ILK/p63 Signaling

Suppression of Hippo pathway in a novel proliferative corneal organ culture system

Epithelial progenitors are preserved in collagenase-digested oral mucosa

Nuclear YAP - promoted proliferation can be induced by lysophosphatidic acid via the PI3K and ROCK pathway s in contact-inhibited human corneal endothelial cells

Corneal Sensitivity and Tear Functions in Patients with Recurrent Corneal Erosion Syndrome

Stem/progenitor properties are preserved during ex vivo expansion of human oral mucosal epithelial cell sheet by collagenase but not dispase

Proliferation induced by lysophosphatidic acid via Hippo-YAP pathway in contact-inhibited human corneal endothelial cells

Relationships of meibomian gland dysfunction and cardiovascular disease risk factors in a middle-aged population

EDC/NHS cross-linked amniotic membrane preferentially preserves corneal epithelial progenitor cells by activating Wnt/β catenin signaling

Expression of Angiogenesis-Related Factors in Human Corneas after Cultivated Oral Mucosal Epithelial Transplantation

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