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Retina November 2020

Preclinical Efficacy and Safety of VEGF-Grab, a Novel Anti-VEGF Drug, and Its Comparison to Aflibercept

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Hye Kyoung Hong; Young Joo Park; Duk Ki Kim; Na-Kyung Ryoo; You-Jin Ko; Kyu Hyung Park; Ho Min Kim; Se Joon Woo

Invest. Ophthalmol. Vis. Sci.. 2020; 61(13):22. doi: https://doi.org/10.1167/iovs.61.13.22

Articles May 2020

Intraocular Distribution and Kinetics of Intravitreally Injected Antibodies and Nanoparticles in Rabbit Eyes

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Hyeong Min Kim; Seungmin Ha; Hye Kyoung Hong; Yoonha Hwang; Pilhan Kim; Eunsol Yang; Jae Yong Chung; Sunyoung Park; Young Joo Park; Kyu Hyung Park; Hyuncheol Kim; Se Joon Woo
TAGS: antibodies, eye, kinetics, molecule, nanoparticles, oryctolagus cuniculus, vitreous body, fluorescence, immunoglobulin g, intravitreal injections
Trans. Vis. Sci. Tech.. 2020; 9(6):20. doi: https://doi.org/10.1167/tvst.9.6.20

Includes: Supplemental Content

Articles March 2020

Intraocular Pharmacokinetics of 10-fold Intravitreal Ranibizumab Injection Dose in Rabbits

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Hyeong Min Kim; Young Joo Park; Simin Lee; Joo Young Son; Hye Kyoung Hong; Min Hee Ham; Xuanyou Jin; Jae Yong Chung; Kyu Hyung Park; Ki Dong Park; Se Joon Woo
TAGS: injections, oryctolagus cuniculus, pharmacokinetics, ranibizumab, kinetics
Trans. Vis. Sci. Tech.. 2020; 9(4):7. doi: https://doi.org/10.1167/tvst.9.4.7

Includes: Supplemental Content

Multidisciplinary Ophthalmic Imaging August 2018

Oxygen-Induced Retinopathy and Choroidopathy: In Vivo Longitudinal Observation of Vascular Changes Using OCTA

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Yongjoo Kim; Hye Kyoung Hong; Jang Ryul Park; WooJhon Choi; Se Joon Woo; Kyu Hyung Park; Wang-Yuhl Oh
TAGS: choroid diseases, diagnostic imaging, eye, oxygen, retinal diseases, retina, face
Invest. Ophthalmol. Vis. Sci.. 2018; 59(10):3932-3942. doi: https://doi.org/10.1167/iovs.18-24320

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Correlation between the light scattering of optical coherence tomography and the mitochondrial content of the neuroretinal lamellae on histology

Jongshin Kim; You-Jin Ko; Hye kyoung Hong; Kyu Hyung Park; David McLeod; Se Joon Woo

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1510. doi:

ARVO Annual Meeting Abstract July 2018

Quantitative analysis on the hyaloid, retinal, and choroidal vessel development and regression using optical coherence tomography angiography

Yongjoo Kim; Hye kyoung Hong; Jingu Lee; Jang Ryul Park; Pilhan Kim; Se Joon Woo; Kyu Hyung Park; Wang-Yuhl Oh

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3924. doi:

Physiology and Pharmacology August 2017

Role of the Fc Region in the Vitreous Half-Life of Anti-VEGF Drugs

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Kwangsic Joo; Sang Jun Park; Yewon Choi; Jung Eun Lee; Young Mi Na; Hye Kyoung Hong; Kyu Hyung Park; Ho Min Kim; Jae-Yong Chung; Se Joon Woo
TAGS: cd40 ligand, half-life, telomeric repeat amplification protocol, thyroid hormone associated protein complex, vascular endothelial growth factor a, vitreous body, proteins, molecular mass, eye, retina
Invest. Ophthalmol. Vis. Sci.. 2017; 58(10):4261-4267. doi: https://doi.org/10.1167/iovs.17-21813

ARVO Annual Meeting Abstract June 2017

Vascular change in oxygen-induced retinopathy rat model observed using retinal optical coherence tomography angiography

Yongjoo Kim; Hye kyoung Hong; Jang Ryul Park; Youjin Koh; WooJhon Choi; Se Joon Woo; Kyu Hyung Park; Wang-Yuhl Oh

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4878. doi:

ARVO Annual Meeting Abstract June 2017

Novel Glycosylated VEGF Decoy Receptor Fusion Protein, VEGF-Grab3 showed superior anti-angiogenic efficacy to Aflibercept (Eylea): a potential therapeutic agent for exudative Age-related macular degeneration (AMD)

Hye kyoung Hong; Eun jin Lim; Na-Kyung Ryoo; Sang Jun Park; Young Mi Na; Jae Yong Chung; Ho Min Kim; Kyu Hyung Park; Se Joon Woo

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1951. doi:

ARVO Annual Meeting Abstract June 2017

The role of Fc portion in the intravitreous half-life of anti-VEGF drugs

Kwangsic Joo; Sang Jun Park; Young Mi Na; Hye kyoung Hong; Yewon Choi; Jung Eun Lee; Hyuncheol Kim; Kyu Hyung Park; Ho Min Kim; Jae Yong Chung; Se Joon Woo

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1202. doi:

ARVO Annual Meeting Abstract September 2016

Preclinical Single photon emission computered tomography/computered tomography(SPECT/CT) imaging of choroidal neovascularization in macular degeneration mice using integrin-binding 99m Tc-IDA-D-[c(RGDfK)] 2

Hye kyoung Hong; Seong Joon Ahn; Se Joon Woo; Kyu Hyung Park; ji hyun park; Jae Ho Jeong; Byung Chul Lee

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2202. doi:

ARVO Annual Meeting Abstract September 2016

Simulating Distribution of Drugs Depending on logP Values in a Rabbit Eye Model

Jihwang Lee; Hye kyoung Hong; Se Joon Woo; Hyuncheol Kim

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6416. doi:

ARVO Annual Meeting Abstract September 2016

Imaging laser-induced choroidal neovascularization in the rodent retina using optical coherence tomography angiography

Jang Ryul Park; WooJhon Choi; Hye kyoung Hong; Yongjoo Kim; Sang Joon Park; Yoonha Hwang; Pilhan Kim; Se Joon Woo; Kyu Hyung Park; Wang-Yuhl Oh

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2204. doi:

Articles July 2016

Imaging Laser-Induced Choroidal Neovascularization in the Rodent Retina Using Optical Coherence Tomography Angiography

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Jang Ryul Park; WooJhon Choi; Hye Kyoung Hong; Yongjoo Kim; Sang Jun Park; Yoonha Hwang; Pilhan Kim; Se Joon Woo; Kyu Hyung Park; Wang-Yuhl Oh
TAGS: angiogram, choroidal neovascularization, diagnostic imaging, lasers, optical coherence tomography, retina, rodentia
Invest. Ophthalmol. Vis. Sci.. 2016; 57(9):OCT331-OCT340. doi: https://doi.org/10.1167/iovs.15-18946

Physiology and Pharmacology May 2016

Intraocular Pharmacokinetics of Intravitreal Aflibercept (Eylea) in a Rabbit Model

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Sang Jun Park; Yewon Choi; Young Mi Na; Hye Kyoung Hong; Ji Yeon Park; Kyu Hyung Park; Jae Yong Chung; Se Joon Woo
TAGS: aflibercept, oryctolagus cuniculus, pharmacokinetics, vitreous body
Invest. Ophthalmol. Vis. Sci.. 2016; 57(6):2612-2617. doi: https://doi.org/10.1167/iovs.16-19204

ARVO Annual Meeting Abstract June 2015

Identification of three plasma protein biomarkers for age-related macular degeneration using a proteomic analysis

Se Joon Woo; Hye-Jung Kim; Jee yun Ahn; Seong Joon Ahn; Hye Kyoung Hong; Na-Kyung Ryoo; Kyu Hyung Park; Cheolju Lee

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):798. doi:

Clinical and Epidemiologic Research November 2014

Identification of Vinculin as a Potential Plasma Marker for Age-Related Macular Degeneration

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Hye-Jung Kim; Se Joon Woo; Eui Jin Suh; Jeeyun Ahn; Ji Hyun Park; Hye Kyoung Hong; Ji Eun Lee; Seong Joon Ahn; Duck Jin Hwang; Ki Woong Kim; Kyu Hyung Park; Cheolju Lee
TAGS: age-related macular degeneration, plasma, proteins, vinculin, plasma proteins, biological markers
Invest. Ophthalmol. Vis. Sci.. 2014; 55(11):7166-7176. doi: https://doi.org/10.1167/iovs.14-15168

Includes: Supplemental Content

ARVO Annual Meeting Abstract April 2014

Alteration of retinal vascular development by postnatal systemic Lipopolysaccharide administration: A novel model of Retinopathy of prematurity (ROP)

Hye kyoung Hong; Joo Youn Oh; Ji Hyun Park; Hyun Joo Lee; Ji Yeon Park; Chang Won Choi; Kyu Hyung Park; Se Joon Woo

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):5389. doi:

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Preclinical Efficacy and Safety of VEGF-Grab, a Novel Anti-VEGF Drug, and Its Comparison to Aflibercept

Intraocular Distribution and Kinetics of Intravitreally Injected Antibodies and Nanoparticles in Rabbit Eyes

Intraocular Pharmacokinetics of 10-fold Intravitreal Ranibizumab Injection Dose in Rabbits

Oxygen-Induced Retinopathy and Choroidopathy: In Vivo Longitudinal Observation of Vascular Changes Using OCTA

Correlation between the light scattering of optical coherence tomography and the mitochondrial content of the neuroretinal lamellae on histology

Quantitative analysis on the hyaloid, retinal, and choroidal vessel development and regression using optical coherence tomography angiography

Role of the Fc Region in the Vitreous Half-Life of Anti-VEGF Drugs

Vascular change in oxygen-induced retinopathy rat model observed using retinal optical coherence tomography angiography

Novel Glycosylated VEGF Decoy Receptor Fusion Protein, VEGF-Grab3 showed superior anti-angiogenic efficacy to Aflibercept (Eylea): a potential therapeutic agent for exudative Age-related macular degeneration (AMD)

The role of Fc portion in the intravitreous half-life of anti-VEGF drugs

Preclinical Single photon emission computered tomography/computered tomography(SPECT/CT) imaging of choroidal neovascularization in macular degeneration mice using integrin-binding 99m Tc-IDA-D-[c(RGDfK)] 2

Simulating Distribution of Drugs Depending on logP Values in a Rabbit Eye Model

Imaging laser-induced choroidal neovascularization in the rodent retina using optical coherence tomography angiography

Imaging Laser-Induced Choroidal Neovascularization in the Rodent Retina Using Optical Coherence Tomography Angiography

Intraocular Pharmacokinetics of Intravitreal Aflibercept (Eylea) in a Rabbit Model

Identification of three plasma protein biomarkers for age-related macular degeneration using a proteomic analysis

Identification of Vinculin as a Potential Plasma Marker for Age-Related Macular Degeneration

Alteration of retinal vascular development by postnatal systemic Lipopolysaccharide administration: A novel model of Retinopathy of prematurity (ROP)

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