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ARVO Annual Meeting Abstract June 2022

Corneo-sclera collagen fibers exhibit substantial transverse inclination

Fengting Ji; Marissa Quinn; Manik Bansal; Yi Hua; Ian A Sigal

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2719 – A0083. doi:

ARVO Annual Meeting Abstract June 2022

Mechanical anisotropy of the equatorial sclera does not concur with its preferred fiber orientation

Yi Hua; Marissa Quinn; Fengting Ji; Samuel Salinas; Rouzbeh Amini; Ian A Sigal

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2731 – A0095. doi:

ARVO Annual Meeting Abstract June 2022

The lamina cribrosa vascular network is heavily interconnected with that of adjacent regions, not just the periphery, likely improving perfusion resilience

Ian A Sigal; Po-Yi Lee; Marissa Quinn; Susannah Waxman; Andrew P Voorhees; Bin Yang; Tatjana C Jakobs; Joseph Rizzo; Brad Fortune; Yi Hua

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4031 – A0416. doi:

ARVO Imaging in the Eye Conference Abstract August 2021

Depth-wise lamina cribrosa deformation while modulating intracerebral pressure

Anse Vellappally; Yoav Glidai; Palaiologos Alexopoulos; Mengling Liu; Ian A. Sigal; Matthew A. Smith; Joel Schuman; Hiroshi Ishikawa; Gadi Wollstein

Invest. Ophthalmol. Vis. Sci.. 2021; 62(11):74. doi:

ARVO Annual Meeting Abstract June 2021

In-vivo evidence of lamina cribrosa deformations induced by chronically elevated IOP in non-human primates

Ian A Sigal; Fuqiang Zhong; Yi Hua; Junchao Wei; Manik Bansal; Juan Reynaud; Brad Fortune

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1862. doi:

ARVO Annual Meeting Abstract June 2021

In-vivo evidence of increased lamina cribrosa compliance at onset of experimental glaucoma in nonhuman primates

Fuqiang Zhong; Yi Hua; Junchao Wei; Manik Bansal; Juan Reynaud; Brad Fortune; Ian A Sigal

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1827. doi:

ARVO Annual Meeting Abstract June 2021

Mechanical properties of scleral collagen fibers obtained using a new fiber-based specimen-specific model of sclera microstructure.

Fengting Ji; Manik Bansal; Bingrui Wang; Yi Hua; Ian A Sigal

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1652. doi:

ARVO Annual Meeting Abstract June 2021

3D eye-specific analysis of factors influencing lamina cribrosa oxygen concentration

Yi Hua; Jason Arthur Walker; Po-Yi Lee; Bryn Brazile; Ian A Sigal

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1021. doi:

ARVO Annual Meeting Abstract June 2021

Research the Anisotropy Property in Equator Sclera Using High Frequency Ultrasonic Elastography

Runze Li; Xuejun Qian; Gengxi Lu; Mark S Humayun; Ian A Sigal; Qifa Zhou

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2313. doi:

ARVO Annual Meeting Abstract June 2021

Under pressure: Response of the lamina cribrosa pore tortuosity to acute pressure changes

Palaiologos Alexopoulos; Behnam Tayebi; Zeinab Ghassabi; Mengfei Wu; Mengling Liu; Yoav Glidai; Katie Lucy; Bo Wang; Ian A Sigal; Matthew Smith; Anse Vellappally; Ronald Zambrano; Hiroshi Ishikawa; Joel S Schuman; Gadi Wollstein

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1866. doi:

Glaucoma November 2020

So-Called Lamina Cribrosa Defects May Mitigate IOP-Induced Neural Tissue Insult

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Andrew P. Voorhees; Yi Hua; Bryn L. Brazile; Bingrui Wang; Susannah Waxman; Joel S. Schuman; Ian A. Sigal

Invest. Ophthalmol. Vis. Sci.. 2020; 61(13):15. doi: https://doi.org/10.1167/iovs.61.13.15

Glaucoma October 2020

Lamina Cribrosa Capillaries Straighten as Intraocular Pressure Increases

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Bryn L. Brazile; Bin Yang; Susannah Waxman; Po Lam; Andrew P. Voorhees; Yi Hua; Ralitsa T. Loewen; Nils A. Loewen; Joseph F. Rizzo, III; Tatjana Jakobs; Ian A. Sigal
TAGS: blood capillaries, cribriform plate, intraocular pressure, vasculature, eye
Invest. Ophthalmol. Vis. Sci.. 2020; 61(12):2. doi: https://doi.org/10.1167/iovs.61.12.2

ARVO Imaging in the Eye Conference Abstract July 2020

Real-time structured polarized light imaging (rtSPLI) for thick ocular tissue dynamics

Bin Yang; Po-Yi Lee; Melissa Echard; Ziyi Zhu; Fengting Ji; Benjamin Bernarding; Ian A. Sigal

Invest. Ophthalmol. Vis. Sci.. 2020; 61(9):PB0022. doi:

ARVO Imaging in the Eye Conference Abstract July 2020

In-Vivo 3D Lamina Cribrosa Microstructure Characterization of Healthy Non-Human Primates

Yoav Glidai; Anoop Sainulabdeen; Mengfei Wu; Matthew A. Smith; Ian A. Sigal; Hiroshi Ishikawa; Joel Schuman; Gadi Wollstein

Invest. Ophthalmol. Vis. Sci.. 2020; 61(9):PP004. doi:

ARVO Annual Meeting Abstract June 2020

Under the Surface: Deformations in the Deep Lamina Cribrosa

Yoav Glidai; Mengfei Wu; Joel S Schuman; Katie Lucy; Ian A Sigal; Matthew A Smith; Hiroshi Ishikawa; Gadi Wollstein

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3529. doi:

ARVO Annual Meeting Abstract June 2020

Local decreases in lamina cribrosa oxygen concentration under elevated IOP are not correlated with the degree of IOP-induced compression

Yi Hua; Haiden McDonald; Jason Walker; Pedro Pallares; Bryn Brazile; Ian A. Sigal

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3532. doi:

ARVO Annual Meeting Abstract June 2020

Characterization of lamina cribrosa beam insertion into the sclera canal in sheep, pig, monkey, and human

Fengting Ji; Bin Yang; Yi Hua; Po-Yi Lee; Ziyi Zhu; Ian A Sigal

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4782. doi:

ARVO Annual Meeting Abstract June 2020

Microstructural evidence that lamina cribrosa beams (LC), peripapillary sclera (PPS) and central retinal artery (CRA) have distinct mechanical behaviors when stretched

Po-Yi Lee; Bin Yang; Ziyi Zhu; Fengting Ji; Yi Hua; Ian A. Sigal

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4783. doi:

ARVO Annual Meeting Abstract June 2020

Interplay between intraocular and intracranial pressure effects on the optic nerve head in vivo

Ian A Sigal; Huong Tran; Ziyi Zhu; Bo Wang; Elizabeth Tyler-Kabara; Hiroshi Ishikawa; Joel S Schuman; Matthew A Smith; Gadi Wollstein

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4785. doi:

ARVO Annual Meeting Abstract June 2020

Factors influencing oxygen concentration in the lamina cribrosa

Jason Arthur Walker; Yi Hua; Haiden McDonald; Pedro Pallares; Bryn Brazile; Ian A. Sigal

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):632. doi:

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Corneo-sclera collagen fibers exhibit substantial transverse inclination

Mechanical anisotropy of the equatorial sclera does not concur with its preferred fiber orientation

The lamina cribrosa vascular network is heavily interconnected with that of adjacent regions, not just the periphery, likely improving perfusion resilience

Depth-wise lamina cribrosa deformation while modulating intracerebral pressure

In-vivo evidence of lamina cribrosa deformations induced by chronically elevated IOP in non-human primates

In-vivo evidence of increased lamina cribrosa compliance at onset of experimental glaucoma in nonhuman primates

Mechanical properties of scleral collagen fibers obtained using a new fiber-based specimen-specific model of sclera microstructure.

3D eye-specific analysis of factors influencing lamina cribrosa oxygen concentration

Research the Anisotropy Property in Equator Sclera Using High Frequency Ultrasonic Elastography

Under pressure: Response of the lamina cribrosa pore tortuosity to acute pressure changes

So-Called Lamina Cribrosa Defects May Mitigate IOP-Induced Neural Tissue Insult

Lamina Cribrosa Capillaries Straighten as Intraocular Pressure Increases

Real-time structured polarized light imaging (rtSPLI) for thick ocular tissue dynamics

In-Vivo 3D Lamina Cribrosa Microstructure Characterization of Healthy Non-Human Primates

Under the Surface: Deformations in the Deep Lamina Cribrosa

Local decreases in lamina cribrosa oxygen concentration under elevated IOP are not correlated with the degree of IOP-induced compression

Characterization of lamina cribrosa beam insertion into the sclera canal in sheep, pig, monkey, and human

Microstructural evidence that lamina cribrosa beams (LC), peripapillary sclera (PPS) and central retinal artery (CRA) have distinct mechanical behaviors when stretched

Interplay between intraocular and intracranial pressure effects on the optic nerve head in vivo

Factors influencing oxygen concentration in the lamina cribrosa

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