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Meeting Abstract (10)
Journal Articles (6)

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Investigative Ophthalmology & Visual Science (16)

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ARVO Annual Meeting Abstract (10)
Glaucoma (6)

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Glaucoma (6)
Eye Anatomy and Disorders (5)
Immunology and Microbiology (3)
Genetics (2)
Retina (2)
Imaging (1)
Nanotechnology and Regenerative Medicine (1)
Pharmacology (1)
Retinal Imaging (1)
Visual Neuroscience (1)

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mice (3)
dna, mitochondrial (2)
intraocular pressure (2)
open-angle glaucoma (2)
adult (1)
anterior chamber of eye (1)
bevacizumab (1)
catheterization (1)
cell lines (1)
concanavalin a (1)

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Glaucoma September 2018

Mitochondrial DNA Variation and Disease Susceptibility in Primary Open-Angle Glaucoma

PDF

Larry N. Singh; Jonathan G. Crowston; M. Isabel G. Lopez Sanchez; Nicole J. Van Bergen; Lisa S. Kearns; Alex W. Hewitt; Seyhan Yazar; David A. Mackey; Douglas C. Wallace; Ian A. Trounce
TAGS: disease susceptibility, dna, mitochondrial, glaucoma, open-angle glaucoma
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4598-4602. https://doi.org/10.1167/iovs.18-25085

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Mitochondria, exercise, diet and the aging retina

Ian A. Trounce

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5344.

ARVO Annual Meeting Abstract July 2018

Protection of the injured optic nerve with forced and voluntary exercise in aged mice: can there be too much of a good thing?

Vicki Chrysostomou; Peter van Wijngaarden; Joseph Paul; Timothy Colgan; Ian A. Trounce; Jonathan G Crowston

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2616.

Glaucoma April 2013

Effect of Anterior Chamber Cannulation and Acute IOP Elevation on Retinal Macrophages in the Adult Mouse

PDF

Jelena M. Kezic; Vicki Chrysostomou; Ian A. Trounce; Paul G. McMenamin; Jonathan G. Crowston
TAGS: catheterization, intraocular pressure, macrophages, mice, adult, anterior chamber of eye, eye
Invest. Ophthalmol. Vis. Sci.. 2013; 54(4):3028-3036. https://doi.org/10.1167/iovs.13-11865

Glaucoma April 2012

Impaired Complex-I-Linked Respiration and ATP Synthesis in Primary Open-Angle Glaucoma Patient Lymphoblasts

PDF

Shanjean Lee; Leo Sheck; Jonathan G. Crowston; Nicole J. Van Bergen; Evelyn C. O'Neill; Fleur O'Hare; Yu Xiang George Kong; Vicki Chrysostomou; Andrea L. Vincent; Ian A. Trounce
TAGS: lymphoblasts, open-angle glaucoma, respiration
Invest. Ophthalmol. Vis. Sci.. 2012; 53(4):2431-2437. https://doi.org/10.1167/iovs.12-9596

ARVO Annual Meeting Abstract March 2012

Defects In Whole Cell Respiration In POAG Lymphoblasts

Jonathan G. Crowston; Leo Sheck; Nicole J. Van Bergen; Shanjean Lee; Vicki Chrysostomou; Andrea L. Vincent; Ian A. Trounce

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):6947.

ARVO Annual Meeting Abstract March 2012

Increased Neuro-retinal Injury After Intraocular Pressure Elevation In Xenomitochondrial Mice And Compensation By Oxphos Complex IV

Ian A. Trounce; Nicole Van Bergen; George Kong; Vicki Chrysostomou; Carl A. Pinkert; Jonathan G. Crowston

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):6571.

ARVO Annual Meeting Abstract March 2012

Exercise Protects Aged Retinal Ganglion Cells from Pressure-Induced Injury

Vicki Chrysostomou; Jelena M. Kezic; Ian A. Trounce; Jonathan G. Crowston

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):4679.

ARVO Annual Meeting Abstract April 2011

Oxidative Phosphorylation Compensation May Preserve Vision In Opa-1-linked Autosomal Dominant Optic Atrophy

Ian A. Trounce; Nicole Van Bergen; David Mackey; Lisa Kearns; Sandra Staffieri; Jonathan Crowston

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):3326.

ARVO Annual Meeting Abstract April 2011

Defects in Mitochondrial Respiration Promote Retinal Ganglion Cell Death and Dysfunction after Short-Term IOP Elevation

Vicki Chrysostomou; George Y. Kong; Nicole Van Bergen; Ian A. Trounce; Jonathan G. Crowston

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):3074.

ARVO Annual Meeting Abstract April 2011

Amyloid Precursor Protein-mediated Neuroprotection In The Aged Retina

Hayley S. Waugh; Kathryn Cimdins; Ian A. Trounce; Jonathan G. Crowston

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):3078.

ARVO Annual Meeting Abstract April 2011

Increase In Mitochondrial DNA Mutations Impairs Retinal Function And Increase Retinal Ganglion Cell Susceptibility To Injury

Yu Xiang George Kong; Ian A. Trounce; Bang V. Bui; Nicole Van Bergen; Vicki Chrysostomou; Hayley Waugh; Algis J. Vingrys; Jonathan G. Crowston

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):3090.

ARVO Annual Meeting Abstract April 2011

Diet Restriction Improves Inner Retinal Recovery Following IOP Injury In Mice With Mitochondrial Dysfunction

Jonathan G. Crowston; George Kong; Nicole Van Bergen; Vicki Chrysostomou; Peter Van Wijngaarden; Algis VIngrys; Bang V. Bui; Ian A. Trounce

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):2602.

Glaucoma December 2010

Antifibrotic Activity of Bevacizumab on Human Tenon's Fibroblasts In Vitro

PDF

Evelyn C. O'Neill; Queena Qin; Nicole J. Van Bergen; Paul P. Connell; Sushil Vasudevan; Michael A. Coote; Ian A. Trounce; Tina T. L. Wong; Jonathan G. Crowston
TAGS: bevacizumab, fibroblasts
Invest. Ophthalmol. Vis. Sci.. 2010; 51(12):6524-6532. https://doi.org/10.1167/iovs.10-5669

Glaucoma December 2009

Functional Changes in the Retina during and after Acute Intraocular Pressure Elevation in Mice

PDF

Yu X. Kong; Jonathan G. Crowston; Algis J. Vingrys; Ian A. Trounce; Bang V. Bui
TAGS: electroretinography, intraocular pressure, mice, erg protein, human
Invest. Ophthalmol. Vis. Sci.. 2009; 50(12):5732-5740. https://doi.org/10.1167/iovs.09-3814

Includes: Supplemental Content

Glaucoma September 2009

Recharacterization of the RGC-5 Retinal Ganglion Cell Line

PDF

Nicole J. Van Bergen; John P. M. Wood; Glyn Chidlow; Ian A. Trounce; Robert J. Casson; Won-Kyu Ju; Robert N. Weinreb; Jonathan G. Crowston
TAGS: cell lines, concanavalin a, dna, glutamate, glutamates, immunoblotting, mice, proteins, retinal ganglion cells, tubulin
Invest. Ophthalmol. Vis. Sci.. 2009; 50(9):4267-4272. https://doi.org/10.1167/iovs.09-3484

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