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ARVO Annual Meeting Abstract June 2024

Characterization and gene-based treatment of a novel CRISPR-Cas9 generated Mak -deficient rat model of photoreceptor degeneration

Lorena Haefeli; Luke A Wiley; Cathryn Cranston; Heather Daggett; Ian Han; Edwin M Stone; Robert F Mullins; Budd A. Tucker

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2216.

ARVO Annual Meeting Abstract June 2024

iPSC derived choroidal endothelial cell delivery using laminin-based hydrogels for the treatment of AMD

Narendra Pandala; Ian Han; Emily Meyering; Edwin M Stone; Robert F Mullins; Budd A. Tucker

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1542.

ARVO Annual Meeting Abstract June 2024

Development of chemically induced choroidal injury models for the study and treatment of AMD.

Ian Han; Narendra Pandala; Lorena Haefeli; Mallory J Lang; Edwin M Stone; Robert F Mullins; Budd A. Tucker

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5382.

ARVO Annual Meeting Abstract June 2024

Transplantation of cGMP compliant iPSC-derived retinal progenitor cells

Laura R Bohrer; Luke A Wiley; Allison T Wright; Louisa Affatigato; Robert F Mullins; Edwin M Stone; Ian Han; Budd A. Tucker

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1541.

ARVO Annual Meeting Abstract June 2024

miR-181 expression and inhibition: a potential new treatment for dominant rhodopsin associated retinitis pigmentosa.

Renato Jensen; Lorena Haefeli; Luke A Wiley; Colleen Stein; Jessica L Fick; Malia Collins; Robert F Mullins; Ian Han; Edwin M Stone; Ryan Boudreau; Budd A. Tucker

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2215.

ARVO Annual Meeting Abstract June 2024

A computational model of retinal atrophy and visual acuity: applications to macular degeneration

S Scott Whitmore; Douglas B Critser; Edwin M Stone; Ian Han

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4454.

ARVO Annual Meeting Abstract June 2024

A dual AAV vector approach for the treatment of ABCA4 -associated retinal disease.

Erin R Burnight; Luke A Wiley; Dalyz Ochoa; Katayoun Varzavand; Seongjin Seo; Ian Han; Robert F Mullins; Edwin M Stone; Budd A. Tucker

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1540.

ARVO Annual Meeting Abstract June 2024

Inflammatory phenotype associated with high risk MMP9 genotype in neovascular AMD

Elliott H Sohn; Zeb Zacharias; kyungmoo lee; Chirantan Mukhopadhyay; Razek Coussa; Ian Han; Todd E Scheetz; John H Fingert; Edwin M Stone; jon houtman; Milan Sonka

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3791.

Retinal Cell Biology October 2023

Gene Expression Within a Human Choroidal Neovascular Membrane Using Spatial Transcriptomics

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Andrew P. Voigt; Nathaniel K. Mullin; Emma M. Navratil; Miles J. Flamme-Wiese; Li-Chun Lin; Todd E. Scheetz; Ian C. Han; Edwin M. Stone; Budd A. Tucker; Robert F. Mullins
TAGS: choroidal neovascularization, gene expression, macular neovascularization, genes, sequence analysis, rna, donors, choroid, eye
Invest. Ophthalmol. Vis. Sci.. 2023; 64(13):40. https://doi.org/10.1167/iovs.64.13.40

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

Autologous choroidal endothelial cell replacement using Laminin based hydrogels for the treatment of AMD.

Narendra Pandala; Ian Han; Emily Meyering; Mallory Lang; Robert Mullins; Budd A. Tucker

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1241.

ARVO Annual Meeting Abstract June 2023

Nanocapsules with HIF-1-alpha Inhibitor for Treatment of Choroidal Neovascularization in a Rat Model

Ian Han; Narendra Pandala; Nuzhat Maisha; Tolulope Ale; Robert Mullins; Erin B Lavik; Budd A. Tucker

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2613.

ARVO Annual Meeting Abstract June 2023

The Waterfall in Disease Progression of Early Onset Stargardt Macular Dystrophy: Implications for Clinical Trial Design

S Scott Whitmore; Douglas B Critser; Adam P DeLuca; Malia M Collins; Austin J Reutzel; Edwin M Stone; Ian Han

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1515.

ARVO Annual Meeting Abstract June 2023

A Retrospective Longitudinal Study of 458 Patients with Molecularly Confirmed ABCA4 -Associated Retinal Disease

Beau Fenner; Adam P DeLuca; S Scott Whitmore; Jeaneen L Andorf; Heather T Daggett; Meagan A Luse; Todd E Scheetz; Budd A. Tucker; Ian Han; Edwin M Stone

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1520.

ARVO Annual Meeting Abstract June 2023

The degree of AAV-induced retinal inflammation varies based on serotype and route of delivery: intravitreal, subretinal or suprachoroidal.

Luke A Wiley; Timothy M Boyce; Dalyz Ochoa; Katie M. Sheehan; Edwin M Stone; Robert Mullins; Budd A. Tucker; Ian Han

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2948.

ARVO Annual Meeting Abstract June 2022

Characterization of a novel Pde6b -deficient rat model of retinal degeneration and treatment with cGMP-grade AAV vectors.

Luke A Wiley; Ian Han; Katie M. Sheehan; Brynnon E. Harman; Megan J. Riker; Edwin M Stone; Robert F Mullins; Budd A. Tucker

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1783 – F0332.

ARVO Annual Meeting Abstract June 2022

Development of a CRISPR dCas9-KRAB based strategy for treatment for dominant retinal degenerative blindness

Erin R Burnight; Luke A Wiley; Malavika K. Adur; Dalyz Ochoa; Emily E. Kaalberg; Mallory Lang; Jeremy M. Hoffman; Chunhua Jiao; Stephen R Russell; Ian Han; Elliott H Sohn; Jason W. Ross; Robert F Mullins; Edwin M Stone; Budd A. Tucker

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1775 – F0324.

ARVO Annual Meeting Abstract June 2022

Choroidal Neovascularization and Associated Structural Features in Best Vitelliform Macular Dystrophy Using Swept-Source Optical Coherence Tomography Angiography

Ian Han; Razek Georges Coussa; Mahsaw Motlagh; Jonathan Russell; D. Brice Critser; Elliott Sohn; Edwin M Stone

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2897 – F0050.

ARVO Annual Meeting Abstract June 2022

Simulating the altered photoreceptor cell topography of progressive retinal dystrophies using OCT images and public data

S Scott Whitmore; Adam P DeLuca; Jeaneen L Andorf; Justine L Cheng; Mahsaw Motlagh; Christopher R Fortenbach; D. Brice Critser; Edwin M Stone; Ian Han

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):197 – F0044.

ARVO Annual Meeting Abstract June 2022

Molecular Characterization of Neovascular AMD in Human Eyes using Spatial Transcriptomics and Single Cell RNA Sequencing

Robert F Mullins; Andrew P Voigt; Todd E Scheetz; Nathaniel Kevin Mullin; Miles J Flamme-Wiese; Li-Chun Lin; Edwin M Stone; Ian Han; Budd A. Tucker

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2316.

ARVO Annual Meeting Abstract June 2021

Pre-clinical toxicity analysis following subretinal transplantation of an iPSC-derived retinal cell graft in immune suppressed rats.

Laura R Bohrer; Ian Han; Jessica A Cooke; Erin R Burnight; Kristin R. Anfinson; Emily K Kaalberg; Mallory J Ulferts; Jeremy M Hoffmann; Kelsey L Wieland; Luke A Wiley; Kristan S Worthington; Katherine N Gibson-Corley; Robert F Mullins; Edwin M Stone; Budd A. Tucker

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2707.

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Characterization and gene-based treatment of a novel CRISPR-Cas9 generated Mak -deficient rat model of photoreceptor degeneration

iPSC derived choroidal endothelial cell delivery using laminin-based hydrogels for the treatment of AMD

Development of chemically induced choroidal injury models for the study and treatment of AMD.

Transplantation of cGMP compliant iPSC-derived retinal progenitor cells

miR-181 expression and inhibition: a potential new treatment for dominant rhodopsin associated retinitis pigmentosa.

A computational model of retinal atrophy and visual acuity: applications to macular degeneration

A dual AAV vector approach for the treatment of ABCA4 -associated retinal disease.

Inflammatory phenotype associated with high risk MMP9 genotype in neovascular AMD

Gene Expression Within a Human Choroidal Neovascular Membrane Using Spatial Transcriptomics

Autologous choroidal endothelial cell replacement using Laminin based hydrogels for the treatment of AMD.

Nanocapsules with HIF-1-alpha Inhibitor for Treatment of Choroidal Neovascularization in a Rat Model

The Waterfall in Disease Progression of Early Onset Stargardt Macular Dystrophy: Implications for Clinical Trial Design

A Retrospective Longitudinal Study of 458 Patients with Molecularly Confirmed ABCA4 -Associated Retinal Disease

The degree of AAV-induced retinal inflammation varies based on serotype and route of delivery: intravitreal, subretinal or suprachoroidal.

Characterization of a novel Pde6b -deficient rat model of retinal degeneration and treatment with cGMP-grade AAV vectors.

Development of a CRISPR dCas9-KRAB based strategy for treatment for dominant retinal degenerative blindness

Choroidal Neovascularization and Associated Structural Features in Best Vitelliform Macular Dystrophy Using Swept-Source Optical Coherence Tomography Angiography

Simulating the altered photoreceptor cell topography of progressive retinal dystrophies using OCT images and public data

Molecular Characterization of Neovascular AMD in Human Eyes using Spatial Transcriptomics and Single Cell RNA Sequencing

Pre-clinical toxicity analysis following subretinal transplantation of an iPSC-derived retinal cell graft in immune suppressed rats.

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