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ARVO Annual Meeting Abstract July 2019

Targeting TFEB (transcription factor EB) as a novel approach for AMD therapy

Stacey L Hose; Sayan Ghosh; Nadezda A. Stepicheva; Sara Jabalameli; Imran Ahmed Bhutto; Peng Shang; Meysam Yazdankhah; Joseph Weiss; Gerard A Lutty; J Samuel Zigler, Jr; Leah Byrne; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1238. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2019

Role of Lipocalin-2 in iron homeostasis and inflammasome activation in pathogenesis of age-related macular degeneration (AMD)

Sayan Ghosh; Peng Shang; Meysam Yazdankhah; Imran Ahmed Bhutto; Nadezda A. Stepicheva; Joseph Weiss; Stacey L Hose; Gerard A Lutty; J Samuel Zigler, Jr; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1345. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2019

A possible role of βA3/A1-crystallin in endocytosis and downstream signaling pathways in RPE cells

Peng Shang; Nadezda A. Stepicheva; Meysam Yazdankhah; Sayan Ghosh; Imran Ahmed Bhutto; Joseph Weiss; Stacey L Hose; J Samuel Zigler, Jr; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1918. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2019

Infiltrating immune cells and pathophysiology in Diabetic Retinopathy (DR)

Imran Ahmed Bhutto; Tanuja Vaidya; Sayan Ghosh; Archana Padmanabhan; Meysam Yazdankhah; Peng Shang; Nadezda A. Stepicheva; Stacey L Hose; J Samuel Zigler, Jr; Santosh GopiKrishna; Thirumalesh MB; Gerard A Lutty; Arkasubhra Ghosh; Swaminathan Sethu; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2683. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2019

Naïve pluripotency improves human diabetic iPSC derived-vascular progenitor cell engraftment and migration in an ischemic retinopathy mouse model

Tea Soon Park; Ludovic Zimmerlin; Imran Ahmed Bhutto; Riya Kanherkar; Rebecca Evans-Moses; Gerard A Lutty; Elias T Zambidis

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2792. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2019

Autophagy is required for maintaining of oligodendrocyte precursor cells in optic nerve

Meysam Yazdankhah; Sayan Ghosh; Imran Ahmed Bhutto; Peng Shang; Nadezda A. Stepicheva; Stacey L Hose; Joseph Weiss; J Samuel Zigler, Jr; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6388. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2019

Lysosomal distribution and function may be affected by the cell type and spatial localization of the cell within the tissue

Nadezda A. Stepicheva; Joseph Weiss; Peng Shang; Meysam Yazdankhah; Sayan Ghosh; Imran Ahmed Bhutto; Stacey L Hose; J Samuel Zigler, Jr; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5981. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2018

Systemic dendrimer-triamcinolone therapy for age-related macular degeneration

Kannan Rangaramanujam; Siva Pramodh Kambhampati; Imran Ahmed Bhutto; Tony P Wu; Scott McLeod; Gerard A Lutty

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):770. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2018

Understanding the role of glial cells (astrocytes and oligodendrocytes) in maintaining the homeostasis of the optic nerve

Meysam Yazdankhah; Rhonda Grebe; Emily G Baxi; Imran Ahmed Bhutto; Stacey L Hose; Amanda N. FairchildBaranowski; Peter Calabresi; J. Samuel Zigler; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):311. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2018

A potent LXR (liver X receptor) agonist can restore lysosome-mediated clearance in RPE cells from a mouse model with AMD-like phenotype

Debasish Sinha; Meysam Yazdankhah; Peng Shang; Cyrille Maugeais; Hasane Ratni; Stacey L Hose; Imran Ahmed Bhutto; Ashwath Jayagopal

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2448. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2018

Loss of functional βA3/A1-crystallin upregulates the expression of colony stimulating factor 1 receptor (CSF-1R) and activates inflammation in Nuc1 rat retina

Stacey L Hose; Sayan Ghosh; Meysam Yazdankhah; Imran Ahmed Bhutto; J. Samuel Zigler, Jr.; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4594. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2018

A Model for Mast Cell Involvement in Geographic Atrophy

Imran Ahmed Bhutto; Rajkumar Baldeosingh; Shuntaro Ogura; Siva Pramodh Kambhampati; Manasee Gedam; Scott McLeod; Malia Michelle Edwards; Julian Esteve-Rudd; Donald Bierer; William Schubert; Gerard A Lutty

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3470. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2018

Targeting neutrophils as a novel approach for AMD therapy

Sayan Ghosh; Peng Shang; Meysam Yazdankhah; Imran Ahmed Bhutto; Stacey L Hose; Gerard A Lutty; J. Samuel Zigler; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3472. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2018

βA3/A1-crystallin is necessary for intracellular protein trafficking in mature RPE cells

Peng Shang; Meysam Yazdankhah; Nadezda Stepicheva; Stacey L Hose; Sayan Ghosh; Imran Ahmed Bhutto; J Samuel Zigler; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3994. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2018

βA3/A1-crystallin affects circadian rhythm of the retinal pigmented epithelium through regulation of GSK3β expression

Nadezda Stepicheva; Peng Shang; Imran Ahmed Bhutto; J Samuel Zigler; Stacey L Hose; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3996. doi: https://doi.org/

ARVO Annual Meeting Abstract June 2017

Loss of βA3/A1-crystallin in astrocytes lead to persistent fetal vasculature (PFV) by activating EGFR/mTORC1 signaling and inhibiting autophagy

Meysam Yazdankhah; Tianqi Luo; Imran Ahmed Bhutto; Peng Shang; Subrata Mishra; Gerard A Lutty; Stacey L Hose; J. Samuel Zigler, Jr.; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1210. doi: https://doi.org/

ARVO Annual Meeting Abstract June 2017

Systemic dendrimer-based combination therapies for AMD

Kannan Rangaramanujam; Siva Pramodh Kambhampati; Imran Ahmed Bhutto; Gerard A Lutty

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1942. doi: https://doi.org/

ARVO Annual Meeting Abstract June 2017

A Possible Role for Mast Cell-Derived Tryptase in the Pathogenesis of Geographic Atrophy

Scott McLeod; Imran Ahmed Bhutto; Malia Michelle Edwards; Manasee Gedam; Raj Baldeosingh; Gerard A Lutty

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2267. doi: https://doi.org/

ARVO Annual Meeting Abstract June 2017

A Rat Model of RPE Atrophy Resembling Human Geographic Atrophy

Imran Ahmed Bhutto; Siva Pramodh Kambhampati; D Scott McLeod; Malia Edwards; Gerard A Lutty

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2289. doi: https://doi.org/

ARVO Annual Meeting Abstract June 2017

Subretinal Lipid Hydroperoxide Induced-Oxidative Stress and Retinal Degeneration Results in a Rat Model of Age-Related Macular Degeneration

Soo-Young Kim; Siva Pramodh Kambhampati; Imran Ahmed Bhutto; Gerard A Lutty; Kannan Rangaramanujam

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2306. doi: https://doi.org/

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Targeting TFEB (transcription factor EB) as a novel approach for AMD therapy

Role of Lipocalin-2 in iron homeostasis and inflammasome activation in pathogenesis of age-related macular degeneration (AMD)

A possible role of βA3/A1-crystallin in endocytosis and downstream signaling pathways in RPE cells

Infiltrating immune cells and pathophysiology in Diabetic Retinopathy (DR)

Naïve pluripotency improves human diabetic iPSC derived-vascular progenitor cell engraftment and migration in an ischemic retinopathy mouse model

Autophagy is required for maintaining of oligodendrocyte precursor cells in optic nerve

Lysosomal distribution and function may be affected by the cell type and spatial localization of the cell within the tissue

Systemic dendrimer-triamcinolone therapy for age-related macular degeneration

Understanding the role of glial cells (astrocytes and oligodendrocytes) in maintaining the homeostasis of the optic nerve

A potent LXR (liver X receptor) agonist can restore lysosome-mediated clearance in RPE cells from a mouse model with AMD-like phenotype

Loss of functional βA3/A1-crystallin upregulates the expression of colony stimulating factor 1 receptor (CSF-1R) and activates inflammation in Nuc1 rat retina

A Model for Mast Cell Involvement in Geographic Atrophy

Targeting neutrophils as a novel approach for AMD therapy

βA3/A1-crystallin is necessary for intracellular protein trafficking in mature RPE cells

βA3/A1-crystallin affects circadian rhythm of the retinal pigmented epithelium through regulation of GSK3β expression

Loss of βA3/A1-crystallin in astrocytes lead to persistent fetal vasculature (PFV) by activating EGFR/mTORC1 signaling and inhibiting autophagy

Systemic dendrimer-based combination therapies for AMD

A Possible Role for Mast Cell-Derived Tryptase in the Pathogenesis of Geographic Atrophy

A Rat Model of RPE Atrophy Resembling Human Geographic Atrophy

Subretinal Lipid Hydroperoxide Induced-Oxidative Stress and Retinal Degeneration Results in a Rat Model of Age-Related Macular Degeneration

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