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ARVO Annual Meeting Abstract September 2016

Inherited optic atrophy gene discovery using whole exome sequencing.

John Simmons Borchert; Isao Nakata; Daniel Navarro-Gomez; Maria Janessian; Elizabeth Delbono; Janey L Wiggs

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5063. doi:

ARVO Annual Meeting Abstract September 2016

Optic nerve magnetic resonance imaging characteristics in inherited optic neuropathies

Eric D Gaier; Katherine Boudreault; Isao Nakata; Dean M Cestari; Janey L Wiggs; Paul Caruso; Joseph F Rizzo

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5078. doi:

Retina August 2015

The Contribution of Genetic Architecture to the 10-Year Incidence of Age-Related Macular Degeneration in the Fellow Eye

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Masahiro Miyake; Kenji Yamashiro; Hiroshi Tamura; Kyoko Kumagai; Masaaki Saito; Masako Sugahara-Kuroda; Munemitsu Yoshikawa; Maho Oishi; Yumiko Akagi-Kurashige; Isao Nakata; Hideo Nakanishi; Norimoto Gotoh; Akio Oishi; Fumihiko Matsuda; Ryo Yamada; Chiea-Chuen Khor; Yasuo Kurimoto; Tetsuju Sekiryu; Akitaka Tsujikawa; Nagahisa Yoshimura
TAGS: age-related macular degeneration, eye, genes, genetics, incidence, genetic risk, cohort studies, single nucleotide polymorphism, cultural formulation interview, disease susceptibility
Invest. Ophthalmol. Vis. Sci.. 2015; 56(9):5353-5361. doi: https://doi.org/10.1167/iovs.14-16020

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2015

Mitochondria haplogroups in patients with dominant optic atrophy

Isao Nakata; Eric D Gaier; Daniel Navarro-Gomez; John Simmons Borchert; Xiaowu Gai; Louis R Pasquale; Simmons Lessell; Dean M Cestari; Joseph F Rizzo; Janey L Wiggs

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3861. doi:

Genetics November 2014

Comprehensive Replication of the Relationship Between Myopia-Related Genes and Refractive Errors in a Large Japanese Cohort

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Munemitsu Yoshikawa; Kenji Yamashiro; Masahiro Miyake; Maho Oishi; Yumiko Akagi-Kurashige; Kyoko Kumagai; Isao Nakata; Hideo Nakanishi; Akio Oishi; Norimoto Gotoh; Ryo Yamada; Fumihiko Matsuda; Nagahisa Yoshimura; for the Nagahama Study Group
TAGS: cohort studies, genes, japanese, myopia, refractive errors, single nucleotide polymorphism
Invest. Ophthalmol. Vis. Sci.. 2014; 55(11):7343-7354. doi: https://doi.org/10.1167/iovs.14-15105

Includes: Supplemental Content

Retina May 2014

Choroidal Neovascularization in Eyes With Choroidal Vascular Hyperpermeability

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Masahiro Miyake; Akitaka Tsujikawa; Kenji Yamashiro; Sotaro Ooto; Akio Oishi; Hiroshi Tamura; Isao Nakata; Fumihiko Matsuda; Nagahisa Yoshimura
TAGS: choroidal neovascularization, eye
Invest. Ophthalmol. Vis. Sci.. 2014; 55(5):3223-3230. doi: https://doi.org/10.1167/iovs.14-14059

Includes: Supplemental Content

ARVO Annual Meeting Abstract April 2014

Association of Age-related Macular Degeneration (AMD) Susceptible Genes with Second Eye Involvement of AMD

Masahiro Miyake; Kenji Yamashiro; Kyoko Kumagai; Hiroshi Tamura; Munemitsu Yoshikawa; Isao Nakata; Hideo Nakanishi; Norimoto Gotoh; Akitaka Tsujikawa; Nagahisa Yoshimura

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):5215. doi:

ARVO Annual Meeting Abstract April 2014

Distribution of OPA1-AS1 genetic variants in patients with optic atrophy

Isao Nakata; Eric D Gaier; Maria Janessian; Elizabeth Delbono; Louis R Pasquale; Simmons Lessell; Dean M Cestari; Joseph F Rizzo; Janey L Wiggs

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):5773. doi:

ARVO Annual Meeting Abstract April 2014

Genome-wide analysis for loci associated with the bilaterality of age-related macular degeneration

Kyoko Kumagai; Kenji Yamashiro; Masahiro Miyake; Munemitsu Yoshikawa; Isao Nakata; Yumiko Akagi-Kurashige; Akitaka Tsujikawa; Ching-Yu Cheng; Chiea chuen Khor; Nagahisa Yoshimura

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2219. doi:

ARVO Annual Meeting Abstract April 2014

Susceptibility genes for large drusen in Japanese

Kenji Yamashiro; Masahiro Miyake; Munemitsu Yoshikawa; Isao Nakata; Hideo Nakanishi; Yumiko Akagi; Kyoko Kumagai; Maho Oishi; Akitaka Tsujikawa; Nagahisa Yoshimura

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2228. doi:

Genetics November 2013

Association Between ZIC2 , RASGRF1 , and SHISA6 Genes and High Myopia in Japanese Subjects

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Maho Oishi; Kenji Yamashiro; Masahiro Miyake; Yumiko Akagi-Kurashige; Kyoko Kumagai; Isao Nakata; Hideo Nakanishi; Munemitsu Yoshikawa; Akio Oishi; Norimoto Gotoh; Akitaka Tsujikawa; Ryo Yamada; Fumihiko Matsuda; Nagahisa Yoshimura
TAGS: genes, japanese, myopia, ras protein specific guanine nucleotide releasing factor 1, single nucleotide polymorphism, choroidal neovascularization
Invest. Ophthalmol. Vis. Sci.. 2013; 54(12):7492-7497. doi: https://doi.org/10.1167/iovs.13-12825

Genetics September 2013

Association Between the Cholesteryl Ester Transfer Protein Gene and Polypoidal Choroidal Vasculopathy

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Isao Nakata; Kenji Yamashiro; Takahisa Kawaguchi; Norimoto Gotoh; Hideo Nakanishi; Yumiko Akagi-Kurashige; Masahiro Miyake; Akitaka Tsujikawa; Akio Oishi; Masaaki Saito; Tomohiro Iida; Ryo Yamada; Fumihiko Matsuda; Nagahisa Yoshimura
TAGS: cholesterol ester transfer proteins, genes, vascular diseases, high density lipoprotein cholesterol
Invest. Ophthalmol. Vis. Sci.. 2013; 54(9):6068-6073. doi: https://doi.org/10.1167/iovs.13-11605

Retina June 2013

Evaluation of Pigment Epithelium–Derived Factor and Complement Factor I Polymorphisms as a Cause of Choroidal Neovascularization in Highly Myopic Eyes

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Masahiro Miyake; Kenji Yamashiro; Hideo Nakanishi; Isao Nakata; Yumiko Akagi-Kurashige; Kyoko Kumagai; Maho Oishi; Akitaka Tsujikawa; Muka Moriyama; Kyoko Ohno-Matsui; Manabu Mochizuki; Nagahisa Yoshimura
TAGS: choroidal neovascularization, complement factor i, cultural formulation interview, eye, pigment, polymorphism, epithelium, myopia, single nucleotide polymorphism
Invest. Ophthalmol. Vis. Sci.. 2013; 54(6):4208-4212. doi: https://doi.org/10.1167/iovs.13-12280

ARVO Annual Meeting Abstract June 2013

Heritability Estimation of Axial Length and Refractive Error Explained by Genome-Wide Single Nucleotide Polymorphisms

Masahiro Miyake; Kenji Yamashiro; Hideo Nakanishi; Isao Nakata; Yumiko Akagi-Kurashige; Kyoko Kumagai; Akitaka Tsujikawa; Ryo Yamada; Fumihiko Matsuda; Nagahisa Yoshimura; Nagahama Study Group

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):1734. doi:

ARVO Annual Meeting Abstract June 2013

Multimodal Evaluation of Macular Function in Age-related Macular Degeneration

Ken Ogino; Akitaka Tsujikawa; Kenji Yamashiro; Sotaro Ooto; Akio Oishi; Isao Nakata; Masahiro Miyake; Ayako Takahashi; Abdallah Ellabban; Nagahisa Yoshimura

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):5030. doi:

Retina May 2013

Intravitreal Injection of Ranibizumab for Recovery of Macular Function in Eyes With Subfoveal Polypoidal Choroidal Vasculopathy

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Ken Ogino; Akitaka Tsujikawa; Kenji Yamashiro; Sotaro Ooto; Akio Oishi; Isao Nakata; Masahiro Miyake; Nagahisa Yoshimura
TAGS: eye, intravitreal injections, macular function, ranibizumab, recovery of function, vascular diseases, exudative retinal detachment
Invest. Ophthalmol. Vis. Sci.. 2013; 54(5):3771-3779. doi: https://doi.org/10.1167/iovs.12-11494

Includes: Supplemental Content

Retina November 2012

Macular Choroidal Thickness Measured by Swept Source Optical Coherence Tomography in Eyes with Inferior Posterior Staphyloma

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Abdallah A. Ellabban; Akitaka Tsujikawa; Akiko Matsumoto; Kenji Yamashiro; Akio Oishi; Sotaro Ooto; Isao Nakata; Yumiko Akagi-Kurashige; Masahiro Miyake; Nagahisa Yoshimura
TAGS: choroid, eye, optical coherence tomography, staphyloma
Invest. Ophthalmol. Vis. Sci.. 2012; 53(12):7735-7745. doi: https://doi.org/10.1167/iovs.12-9952

Genetics September 2012

Association of Genetic Variants on 8p21 and 4q12 with Age-Related Macular Degeneration in Asian Populations

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Isao Nakata; Kenji Yamashiro; Yumiko Akagi-Kurashige; Masahiro Miyake; Kyoko Kumagai; Akitaka Tsujikawa; Ke Liu; Li Jia Chen; David T. L. Liu; Timothy Y. Y. Lai; Yoichi Sakurada; Seigo Yoneyama; Ching-Yu Cheng; Peter Cackett; Ian Y. Yeo; Wan Ting Tay; Belinda K. Cornes; Eranga N. Vithana; Tin Aung; Keitaro Matsuo; Fumihiko Matsuda; Tien-Yin Wong; Hiroyuki Iijima; Chi Pui Pang; Nagahisa Yoshimura
TAGS: age-related macular degeneration, asian, cohort studies, exudative age-related macular degeneration, genetics, japanese, chinese (other dialects), choroidal neovascularization, chinese people, meta-analysis
Invest. Ophthalmol. Vis. Sci.. 2012; 53(10):6576-6581. doi: https://doi.org/10.1167/iovs.12-10219

Retina June 2012

Choroidal Thickness, Vascular Hyperpermeability, and Complement Factor H in Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy

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Pichai Jirarattanasopa; Sotaro Ooto; Isao Nakata; Akitaka Tsujikawa; Kenji Yamashiro; Akio Oishi; Nagahisa Yoshimura
TAGS: age-related macular degeneration, complement factor h, eye, vascular diseases, ranibizumab
Invest. Ophthalmol. Vis. Sci.. 2012; 53(7):3663-3672. doi: https://doi.org/10.1167/iovs.12-9619

Retina April 2012

Vascular Endothelial Growth Factor Gene Polymorphisms and Choroidal Neovascularization in Highly Myopic Eyes

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Yumiko Akagi-Kurashige; Kyoko Kumagai; Kenji Yamashiro; Hideo Nakanishi; Isao Nakata; Masahiro Miyake; Akitaka Tsujikawa; Muka Moriyama; Kyoko Ohno-Matsui; Manabu Mochizuki; Ryo Yamada; Fumihiko Matsuda; Nagahisa Yoshimura
TAGS: choroidal neovascularization, eye, genes, polymorphism, vascular endothelial growth factor a
Invest. Ophthalmol. Vis. Sci.. 2012; 53(4):2349-2353. doi: https://doi.org/10.1167/iovs.11-9405

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Inherited optic atrophy gene discovery using whole exome sequencing.

Optic nerve magnetic resonance imaging characteristics in inherited optic neuropathies

The Contribution of Genetic Architecture to the 10-Year Incidence of Age-Related Macular Degeneration in the Fellow Eye

Mitochondria haplogroups in patients with dominant optic atrophy

Comprehensive Replication of the Relationship Between Myopia-Related Genes and Refractive Errors in a Large Japanese Cohort

Choroidal Neovascularization in Eyes With Choroidal Vascular Hyperpermeability

Association of Age-related Macular Degeneration (AMD) Susceptible Genes with Second Eye Involvement of AMD

Distribution of OPA1-AS1 genetic variants in patients with optic atrophy

Genome-wide analysis for loci associated with the bilaterality of age-related macular degeneration

Susceptibility genes for large drusen in Japanese

Association Between ZIC2 , RASGRF1 , and SHISA6 Genes and High Myopia in Japanese Subjects

Association Between the Cholesteryl Ester Transfer Protein Gene and Polypoidal Choroidal Vasculopathy

Evaluation of Pigment Epithelium–Derived Factor and Complement Factor I Polymorphisms as a Cause of Choroidal Neovascularization in Highly Myopic Eyes

Heritability Estimation of Axial Length and Refractive Error Explained by Genome-Wide Single Nucleotide Polymorphisms

Multimodal Evaluation of Macular Function in Age-related Macular Degeneration

Intravitreal Injection of Ranibizumab for Recovery of Macular Function in Eyes With Subfoveal Polypoidal Choroidal Vasculopathy

Macular Choroidal Thickness Measured by Swept Source Optical Coherence Tomography in Eyes with Inferior Posterior Staphyloma

Association of Genetic Variants on 8p21 and 4q12 with Age-Related Macular Degeneration in Asian Populations

Choroidal Thickness, Vascular Hyperpermeability, and Complement Factor H in Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy

Vascular Endothelial Growth Factor Gene Polymorphisms and Choroidal Neovascularization in Highly Myopic Eyes

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