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Visual Neuroscience November 2020

Thyroid Activating Enzyme, Deiodinase II Is Required for Photoreceptor Function in the Mouse Model of Retinopathy of Prematurity

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Onkar B. Sawant; Vijay K. Jidigam; Kenya Wilcots; Rebecca D. Fuller; Ivy Samuels; Sujata Rao

Invest. Ophthalmol. Vis. Sci.. 2020; 61(13):36. doi: https://doi.org/10.1167/iovs.61.13.36

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Reduction of GLUT1 in the BKS. Lepr db/db mouse model of Type 2 diabetes ameliorates retinal pathology and defects in retinal function.

Ivy S Samuels; Jacob J Aiello; Timothy D Trobenter; Nicholas C Holoman

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5359. doi:

Retina April 2019

Transducin1, Phototransduction and the Development of Early Diabetic Retinopathy

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Haitao Liu; Jie Tang; Yunpeng Du; Aicha Saadane; Ivy Samuels; Alex Veenstra; Jianying Z. Kiser; Krzysztof Palczewski; Timothy S. Kern
TAGS: diabetes mellitus, diabetes mellitus, type 2, diabetic retinopathy, mice, phototransduction, photoreceptors, retina, vision, rod photoreceptors, tissue degeneration
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1538-1546. doi: https://doi.org/10.1167/iovs.18-26433

ARVO Annual Meeting Abstract July 2018

Modulation of GLUT1 expression in the RPE impacts outer segment renewal and results in photoreceptor degeneration

Aditi Swarup; Ivy S. Samuels; Jamie Soto; E. Dale Abel; Neal Peachey; Nancy J Philp

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4967. doi:

ARVO Annual Meeting Abstract July 2018

Systemic reduction of GLUT1 prevents hallmarks of diabetic retinopathy

Ivy S Samuels; Matthew Tarchick; Timothy D. Trobenter; Michael R. Kozlowski

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5361. doi:

ARVO Annual Meeting Abstract June 2017

Circadian clock gene Bmal1 is necessary to establish the S-opsin gradient in murine cone photoreceptors

Onkar Sawant; Amanda Horton; Ivy S Samuels; Sujata Rao

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5601. doi:

ARVO Annual Meeting Abstract June 2017

Photoreceptor outer segment changes observed in rodent models by SDOCT: An early indicator of stress and dysfunction?

Brent A Bell; Ivy S Samuels; Mary E Rayborn; Alecia Cutler; Bela Anand-Apte; Joe G Hollyfield; Vera L Bonilha

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4863. doi:

ARVO Annual Meeting Abstract June 2017

Loss of GLUT1 in the retinal pigment epithelium does not diminish its function, differentiation or polarity.

Ivy S Samuels; Aditi Swarup; Craig Beight; John Y.S. Han; Jamie Soto; E Dale Dale Abel; Neal S Peachey; Nancy J Philp

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3023. doi:

ARVO Annual Meeting Abstract June 2017

Montelukast modulates diabetes-induced inflammation and electrophysiological changes in early diabetic retinopathy in the mouse

Reena Bapputty; Ivy S Samuels; Ramaprasad Talahalli; Rose Anne Gubitosi-Klug

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5219. doi:

ARVO Annual Meeting Abstract June 2017

The role insulin receptor-mediated signaling from the RPE in the development of retinal oxidative stress and inflammation in the STZ-induced mouse model of diabetes.

Matthew J. Tarchick; Alecia Cutler; Bela Anand-Apte; Ivy S Samuels

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5798. doi:

ARVO Annual Meeting Abstract September 2016

Role of Type II deiodinase (Dio2) and circadian clock gene Bmal1 in photoreceptor development

Onkar Sawant; Banumathi Tamilselvan; Amanda Horton; Ivy S Samuels; Sujata Rao

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):563. doi:

ARVO Annual Meeting Abstract September 2016

The contribution of RPE-specific insulin signaling to the development of outer retina dysfunction associated with diabetes.

Ivy S Samuels; Alecia H. Cutler; Matthew J. Tarchick; Bela Anand-Apte

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5422. doi:

ARVO Annual Meeting Abstract September 2016

Age-related degeneration of the retinal pigment epithelium (RPE) of DJ-1 mice.

Vera L Bonilha; Brent A Bell; Mary E Rayborn; Joe G Hollyfield; Ivy S Samuels; Chengsong Xie; Huaibin Cai

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6038. doi:

Retina August 2016

Photoreceptor Cells Influence Retinal Vascular Degeneration in Mouse Models of Retinal Degeneration and Diabetes

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Haitao Liu; Jie Tang; Yunpeng Du; Aicha Saadane; Deoye Tonade; Ivy Samuels; Alex Veenstra; Krzysztof Palczewski; Timothy S. Kern
TAGS: diabetes mellitus, diabetes mellitus, type 2, mice, opsin, photoreceptors, tissue degeneration, blood capillaries, retinal degeneration, mice, inbred c57bl
Invest. Ophthalmol. Vis. Sci.. 2016; 57(10):4272-4281. doi: https://doi.org/10.1167/iovs.16-19415

Visual Neuroscience June 2016

Early Functional and Morphologic Abnormalities in the Diabetic Nyx nob Mouse Retina

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Matthew J. Tarchick; Parastoo Bassiri; Rebecca M. Rohwer; Ivy S. Samuels
TAGS: diabetes mellitus, mice, retina, electroretinography, streptozocin
Invest. Ophthalmol. Vis. Sci.. 2016; 57(7):3496-3508. doi: https://doi.org/10.1167/iovs.15-18775

ARVO Annual Meeting Abstract June 2015

DSCAM restricts neurite lamination in the mouse inner retina

Peter G Fuerst; Shuai Li; Ivy S Samuels; Aaron Simmons

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):1477. doi:

ARVO Annual Meeting Abstract June 2015

Diabetes-induced c-wave reductions are independent of the M ü ller glia-generated Kir4.1-mediated [K+] conductance and are correlated with elevated GLUT1 levels.

Ivy S Samuels; Janet C. Peachey; Parastoo Bassiri; Lindsey A Ebke; Brent A Bell

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4293. doi:

ARVO Annual Meeting Abstract April 2014

Lepr db/db mouse models of Type 2 diabetes exhibit rapid defects in RPE electrophysiology that correlate with systemic hyperglycemia.

Ivy S Samuels; Brent A Bell; Neal S Peachey

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1639. doi:

Visual Neuroscience November 2013

Myosin 6 Is Required for Iris Development and Normal Function of the Outer Retina

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Ivy S. Samuels; Brent A. Bell; Gwen Sturgill-Short; Lindsey A. Ebke; Mary Rayborn; Lanying Shi; Patsy M. Nishina; Neal S Peachey
TAGS: homozygote, mice, myosins, retina, electroretinography, iris development, iris
Invest. Ophthalmol. Vis. Sci.. 2013; 54(12):7223-7233. doi: https://doi.org/10.1167/iovs.13-12887

ARVO Annual Meeting Abstract June 2013

Unconvential Myosin VI motor protein is required for iris development and outer retinal function

Ivy Samuels; Brent Bell; Gwen Sturgill-Short; Lan Ying Shi; Neal Peachey; Patsy Nishina

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):2501. doi:

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Thyroid Activating Enzyme, Deiodinase II Is Required for Photoreceptor Function in the Mouse Model of Retinopathy of Prematurity

Reduction of GLUT1 in the BKS. Lepr db/db mouse model of Type 2 diabetes ameliorates retinal pathology and defects in retinal function.

Transducin1, Phototransduction and the Development of Early Diabetic Retinopathy

Modulation of GLUT1 expression in the RPE impacts outer segment renewal and results in photoreceptor degeneration

Systemic reduction of GLUT1 prevents hallmarks of diabetic retinopathy

Circadian clock gene Bmal1 is necessary to establish the S-opsin gradient in murine cone photoreceptors

Photoreceptor outer segment changes observed in rodent models by SDOCT: An early indicator of stress and dysfunction?

Loss of GLUT1 in the retinal pigment epithelium does not diminish its function, differentiation or polarity.

Montelukast modulates diabetes-induced inflammation and electrophysiological changes in early diabetic retinopathy in the mouse

The role insulin receptor-mediated signaling from the RPE in the development of retinal oxidative stress and inflammation in the STZ-induced mouse model of diabetes.

Role of Type II deiodinase (Dio2) and circadian clock gene Bmal1 in photoreceptor development

The contribution of RPE-specific insulin signaling to the development of outer retina dysfunction associated with diabetes.

Age-related degeneration of the retinal pigment epithelium (RPE) of DJ-1 mice.

Photoreceptor Cells Influence Retinal Vascular Degeneration in Mouse Models of Retinal Degeneration and Diabetes

Early Functional and Morphologic Abnormalities in the Diabetic Nyx nob Mouse Retina

DSCAM restricts neurite lamination in the mouse inner retina

Diabetes-induced c-wave reductions are independent of the M ü ller glia-generated Kir4.1-mediated [K+] conductance and are correlated with elevated GLUT1 levels.

Lepr db/db mouse models of Type 2 diabetes exhibit rapid defects in RPE electrophysiology that correlate with systemic hyperglycemia.

Myosin 6 Is Required for Iris Development and Normal Function of the Outer Retina

Unconvential Myosin VI motor protein is required for iris development and outer retinal function

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