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Meeting Abstract (57)
Journal Articles (19)

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Investigative Ophthalmology & Visual Science (76)

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ARVO Annual Meeting Abstract (57)
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ARVO Annual Meeting Abstract June 2023

SIRT5/Akt2 signaling axis regulates TFEB activity and autophagy in the RPE cells: Implications in dry age-related macular degeneration

Sayan Ghosh; Victoria Koontz; Mihir Nemani; Olivia Chowdhury; Haitao Liu; Stacey L Hose; J. Samuel Zigler Jr.; James T Handa; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5389.

ARVO Annual Meeting Abstract June 2023

Akt2 signaling in RPE contributes to retinal fibrosis in DR

Haitao Liu; Vishnu Maddipatla; Sayan Ghosh; Victoria Koontz; Stacey L Hose; J. Samuel Zigler Jr.; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):498.

ARVO Annual Meeting Abstract June 2022

The differential role of distinct astrocyte populations in Persistent Fetal Vasculature (PFV) disease

Victoria Koontz; Sayan Ghosh; Nadezda A Stepicheva; Haitao Liu; PENG SHANG; Olivia Chowdhury; Anastasiia Strizhakova; Rachel Daley; Stacey L Hose; J. Samuel Zigler; Meysam Yazdankhah; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):266 – F0311.

ARVO Annual Meeting Abstract June 2022

βA3/A1-crystallin may link lysosomal clearance and the circadian rhythm in the RPE

Anastasiia Strizhakova; Adithya Sreenivas; Victoria Koontz; Peng Shang; Haitao Liu; Sayan Ghosh; Olivia Chowdhury; Stacey L Hose; J. Samuel Zigler; Nadezda A Stepicheva; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):778 – F0337.

ARVO Annual Meeting Abstract June 2022

PITPβ/βA3/A1-crystallin complex is critical for PIP metabolism in retinal pigment epithelium (RPE)

Emma Rose Mahally; Rachel Daley; Kenneth Teel; Austin McCauley; Nadezda A Stepicheva; Sayan Ghosh; Haitao Liu; Olivia Chowdhury; Anastasiia Strizhakova; Victoria Koontz; Stacey L Hose; J. Samuel Zigler; Raju V S Rajala; Debasish Sinha; PENG SHANG

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2473 – F0180.

ARVO Annual Meeting Abstract June 2022

Looking for hidden cues: can the function of the moonlighting ocular protein βA3/A1-crystallin be regulated by the signals hidden in its coding sequence?

Nadezda A Stepicheva; Ekaterina Volkova; Victoria Koontz; PENG SHANG; Haitao Liu; Sayan Ghosh; Anastasiia Strizhakova; Olivia Chowdhury; Rachel Daley; J. Samuel Zigler; Stacey L Hose; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2300.

ARVO Annual Meeting Abstract June 2022

Inhibiting mTOR-independent TFEB activity in RPE alleviates the early AMD-like phenotype in a mouse model

Mihir Nemani; Haitao Liu; PENG SHANG; Olivia Chowdhury; Victoria Koontz; Nadezda A Stepicheva; Anastasiia Strizhakova; Rachel Daley; Stacey L Hose; J. Samuel Zigler; Debasish Sinha; Sayan Ghosh

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3038 – F0409.

ARVO Annual Meeting Abstract June 2022

Activation of mTOR signaling in the RPE cells induces alterations in melanogenesis thereby triggering oxidative stress

Olivia Chowdhury; Vishnu Maddipatla; Sayan Ghosh; Haitao Liu; PENG SHANG; Victoria Koontz; Nadezda A Stepicheva; Anastasiia Strizhakova; Rachel Daley; Stacey L Hose; J. Samuel Zigler; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3033 – F0404.

ARVO Annual Meeting Abstract June 2022

Akt2 signaling in diabetes-induced dysfunction of the outer blood retina barrier

Rachel Daley; Sayan Ghosh; PENG SHANG; Nadezda A Stepicheva; Anastasiia Strizhakova; Olivia Chowdhury; Victoria Koontz; Stacey L Hose; J. Samuel Zigler; Debasish Sinha; Haitao Liu

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3599 – A0054.

ARVO Annual Meeting Abstract June 2022

HDAC11 is a crucial regulator for visual cycle genes and retinal function

Peng Shang; Rachel Daley; Emma Rose Mahally; Nadezda A Stepicheva; Sayan Ghosh; Haitao Liu; Anastasiia Strizhakova; Olivia Chowdhury; Victoria Koontz; Stacey L Hose; J. Samuel Zigler; Jiang Qian; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4115 – F0352.

ARVO Annual Meeting Abstract June 2022

Crosstalk between metabolism and inflammation in dry age-related macular degeneration

Sayan Ghosh; PENG SHANG; Nadezda A Stepicheva; Haitao Liu; Olivia Chowdhury; Victoria Koontz; Anastasiia Strizhakova; Rachel Daley; Stacey L Hose; J. Samuel Zigler; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4625 – F0417.

ARVO Annual Meeting Abstract June 2022

Lipocalin-2 homodimer variant: Role in dry age-related macular degeneration

Urvi Gupta; Sayan Ghosh; PENG SHANG; Haitao Liu; Anastasiia Strizhakova; Stacey L Hose; J. Samuel Zigler; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4602 – F0394.

ARVO Annual Meeting Abstract June 2020

Mitochondrial abnormality in astrocytes leads to optic nerve degeneration: a mechanism mediated by CXCL14

Meysam Yazdankhah; Emily G. Boxi; Stacey L Hose; Nadezda A Stepicheva; Joseph Weiss; Sayan Ghosh; Peng Shang; Haitao Liu; Christopher Scott Fitting; Ming-Wen Hu; Jiang Qian; Peter Calabresi; J. Samuel Zigler; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2791.

ARVO Annual Meeting Abstract June 2020

Akt2 overexpression in RPE cells drives retinal degeneration: a novel model to study inflammation in atrophic AMD

Sayan Ghosh; Hai Tao Liu; Peng Shang; Meysam Yazdankhah; Nadezda A Stepicheva; Joseph Weiss; Christopher Scott Fitting; Stacey L Hose; J. Samuel Zigler; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2794.

ARVO Annual Meeting Abstract June 2020

A possible role of βA3/A1-crystallin in clathrin-mediated endocytosis and maintenance of microvilli of RPE cells

Peng Shang; Christopher Scott Fitting; Meysam Yazdankhah; Nadezda A Stepicheva; Sayan Ghosh; Haitao Liu; Joseph Weiss; Stacey L Hose; J. Samuel Zigler; Simon Watkins; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4152.

ARVO Annual Meeting Abstract June 2020

Akt2 signaling in retinal pigment epithelial cells contributes to the development of diabetic retinopathy

Haitao Liu; J. Samuel Zigler; Ashwath Jayagopal; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4157.

ARVO Annual Meeting Abstract July 2019

Targeting TFEB (transcription factor EB) as a novel approach for AMD therapy

Stacey L Hose; Sayan Ghosh; Nadezda A. Stepicheva; Sara Jabalameli; Imran Ahmed Bhutto; Peng Shang; Meysam Yazdankhah; Joseph Weiss; Gerard A Lutty; J Samuel Zigler, Jr; Leah Byrne; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1238.

ARVO Annual Meeting Abstract July 2019

Autophagy is required for maintaining of oligodendrocyte precursor cells in optic nerve

Meysam Yazdankhah; Sayan Ghosh; Imran Ahmed Bhutto; Peng Shang; Nadezda A. Stepicheva; Stacey L Hose; Joseph Weiss; J Samuel Zigler, Jr; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6388.

ARVO Annual Meeting Abstract July 2019

Role of Lipocalin-2 in iron homeostasis and inflammasome activation in pathogenesis of age-related macular degeneration (AMD)

Sayan Ghosh; Peng Shang; Meysam Yazdankhah; Imran Ahmed Bhutto; Nadezda A. Stepicheva; Joseph Weiss; Stacey L Hose; Gerard A Lutty; J Samuel Zigler, Jr; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1345.

ARVO Annual Meeting Abstract July 2019

A possible role of βA3/A1-crystallin in endocytosis and downstream signaling pathways in RPE cells

Peng Shang; Nadezda A. Stepicheva; Meysam Yazdankhah; Sayan Ghosh; Imran Ahmed Bhutto; Joseph Weiss; Stacey L Hose; J Samuel Zigler, Jr; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1918.

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