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ARVO Annual Meeting Abstract June 2024

A randomized, active-controlled, patient and investigator-masked, multiple dose Ph2 study of intravitreal LKA651, an anti-erythropoietin (EPO) antibody fragment, in patients with diabetic macular edema

Nadia Zakaria; Danielle Spera; Katy Hayes; Tingting Zhai; Brijesh Yadav; Jorge Aranda; Darlene Lu; Melissa Liew

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6262.

ARVO Annual Meeting Abstract June 2023

ABCA1 activity in the RPE is unnecessary for RPE reverse cholesterol transport (RCT) and AMD pathophysiology

Matthew Coble; Jorge Aranda; John T Demirs; Robert Esterberg; Shawn Hanks; Sandra Jose; Barrett Leehy; Sha-Mei Liao; Yiyun Zhang; Sheng-Yong Niu; Yubin Qiu; Junzheng Yang

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3515.

ARVO Annual Meeting Abstract July 2019

Characterization of a mouse model of RPE pathology

Ivana Arellano; Hui Li; Jorge Aranda; Shawn Hanks; Tim Pagliaro; Joanna Vrouvlianis; Nalini V Rangaswamy; Chad E Bigelow; Stephen H Poor

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):192.

ARVO Annual Meeting Abstract July 2019

Erythropoietin (EPO) overexpression induces a DME-like phenotype in the mouse retina

Jorge Aranda; Nalini V Rangaswamy; Hui Li; Joanna Vrouvlianis; Maura Crowley; John T Demirs; Junzheng Yang; Adrian Will-Orrego; Terri McGee; Chad E Bigelow; Stephen H Poor

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3664.

ARVO Annual Meeting Abstract July 2018

Development of an ex vivo assay to measure mitochondrial metabolism of mouse posterior eye tissue

Steve Louie; Barrett Leehy; Hui Li; Jorge Aranda; Stephen H Poor; Tony Walshe

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4009.

ARVO Annual Meeting Abstract September 2016

Comparative Effects of Bevacizumab and Aflibercept on VEGF and IGF Signaling in Human Retinal Endothelial Cells Exposed to Hyperoxia and Intermittent Hypoxia

Amirfarbod Yazdanyar; Charles Cai; Ahmad Taimur; Eric shrier; Douglas R Lazzaro; Gloria Valencia; Jacob Aranda; Kay Beharry

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3358.

ARVO Annual Meeting Abstract June 2015

Development and Characterization of a new Mouse Model of Proliferative Diabetic Retinopathy

Ashley Michael Mackey; Jorge Aranda; Chiara Gerhardinger; Andrius Kazlauskas

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4676.

Retina March 2015

Exogenous Superoxide Dismutase Mimetic Without Scavenging H 2 O 2 Causes Photoreceptor Damage in a Rat Model for Oxygen-Induced Retinopathy

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Shamin Jivabhai Patel; Fayez Bany-Mohammed; Lois McNally; Gloria B. Valencia; Douglas R. Lazzaro; Jacob V. Aranda; Kay D. Beharry
TAGS: antioxidants, normal saline, oxidative stress, oxygen, photoreceptors, retina, retinal diseases, saline solutions, superoxide dismutase, vascular endothelial growth factor a
Invest. Ophthalmol. Vis. Sci.. 2015; 56(3):1665-1677. https://doi.org/10.1167/iovs.14-15321

Includes: Supplemental Content

ARVO Annual Meeting Abstract April 2014

Response of Human Retinal Endothelial Cells (HRECs) to Small Interfering RNA (SiRNA) Silencing of Notch-1, Delta-Like Ligand 4 (Dll4), and Jagged-1 During Hyperoxia with Intermittent Hypoxia (IH).

Kay D Beharry; Charles L Cai; Taimur Ahmad; Gloria B Valencia; Douglas R Lazzaro; Jacob V Aranda

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):5375.

Translational Research November 2013

Hydrogen Peroxide Accumulation in the Choroid During Intermittent Hypoxia Increases Risk of Severe Oxygen-Induced Retinopathy in Neonatal Rats

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Kay D. Beharry; Charles L. Cai; Poonam Sharma; Vadim Bronshtein; Gloria B. Valencia; Douglas R. Lazzaro; Jacob V. Aranda
TAGS: choroid, hydrogen peroxide, hypoxia, mitochondria, newborn, oxygen, rats, retina, retinal diseases, blood gas
Invest. Ophthalmol. Vis. Sci.. 2013; 54(12):7644-7657. https://doi.org/10.1167/iovs.13-13040

ARVO Annual Meeting Abstract June 2013

Retinal Protease and Collagen Responses to Increasing Numbers of Intermittent Hypoxia During Hyperoxia in a Rat Model for Oxygen-Induced Retinopathy

Kay Beharry; Charles Cai; Poonam Sharma; Gloria Valencia; Douglas Lazzaro; Jacob Aranda

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):5568.

ARVO Annual Meeting Abstract March 2012

Mixed Arterial-Venous PO2 Levels Critical to Ocular Markers of Angiogenesis and Oxidative Stress in Neonatal Rats

William J. Brunken; Charles L. Cai; Dharmendra Kumar; Gloria B. Valencia; Jacob V. Aranda; Kay D. Beharry

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):2528.

ARVO Annual Meeting Abstract April 2011

Matrix Metalloproteinases in the Vitreous Cleave Prolactin to Vasoinhibins

Mayda Ramirez; Jorge Aranda; Edith Arnold; Nundehui Diaz-Lezama; Carlos Alvarez-Guzman; Yazmin Macotela; Gonzalo Martinez de la Escalera; Carmen Clapp

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):4890.

ARVO Annual Meeting Abstract April 2009

Diabetic Retinopathy Is Associated With Increased Vascular Stability

J. Aranda; Y. Sassa; M. Prakash; P. Silva; L. Aiello; A. Kazlauskas

Invest. Ophthalmol. Vis. Sci.. 2009; 50(13):17.

ARVO Annual Meeting Abstract May 2008

Vasoinhibins Prevent the Diabetic Retinopathy-Associated Vascular Leakage in vivo via Protein Phosphatase 2A-Dependent eNOS Inactivation

E. Arnold; J. Aranda; C. Garcia; S. Thebault; F. Lopez-Barrera; H. Quiroz-Mercado; G. Martinez de la Escalera; C. Clapp

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):1347.

ARVO Annual Meeting Abstract May 2007

Vasoinhibins Inhibit Vascular Leakage and Vasodilation Induced by VEGF in the Retina

J. Aranda; E. Arnold; C. Vega-Cázares; J. Rivera; G. Martínez de la Escalera; C. Clapp

Invest. Ophthalmol. Vis. Sci.. 2007; 48(13):3418.

ARVO Annual Meeting Abstract May 2007

Prolactin Protects Photoreceptors From Light Damage in vivo

E. Arnold Hernandez; J. Rivera; J. Aranda; C. Vega; A. Quintanar-Stephano; G. Martinez de la Escalera; C. Clapp

Invest. Ophthalmol. Vis. Sci.. 2007; 48(13):1344.

ARVO Annual Meeting Abstract May 2007

Prolactin Decreases in the Circulation of Patients with Proliferative Diabetic Retinopathy: Relationship to Intraocular Vasoinhibins

J. Rivera; D. Moreno-Páramo; J. Aranda; E. Arnold; F. López-Barrera; N. Salazar; H. Quiroz-Mercado; G. Martínez de la Escalera; C. Clapp

Invest. Ophthalmol. Vis. Sci.. 2007; 48(13):1408.

Retina July 2006

Comparative Effects of Early Postnatal Ibuprofen and Indomethacin on VEGF, IGF-I, and GH during Rat Ocular Development

PDF

Kay D. A. Beharry; Houchang D. Modanlou; Jamal Hasan; Zahra Gharraee; Patricia Abad-Santos; Jeremy H. Sills; Amanda Jan; Stephen Nageotte; Jacob V. Aranda
TAGS: ibuprofen, indomethacin, insulin-like growth factor i, vascular endothelial growth factor a, eye development
Invest. Ophthalmol. Vis. Sci.. 2006; 47(7):3036-3043. https://doi.org/10.1167/iovs.06-0057

ARVO Annual Meeting Abstract May 2006

Localization of Prolactin and the Prolactin Receptor in Rat Retina

J. Rivera; J. Aranda; J. Riesgo; F. Lopez–Barrera; G. Martínez de la Escalera; C. Clapp

Invest. Ophthalmol. Vis. Sci.. 2006; 47(13):171.

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A randomized, active-controlled, patient and investigator-masked, multiple dose Ph2 study of intravitreal LKA651, an anti-erythropoietin (EPO) antibody fragment, in patients with diabetic macular edema

ABCA1 activity in the RPE is unnecessary for RPE reverse cholesterol transport (RCT) and AMD pathophysiology

Characterization of a mouse model of RPE pathology

Erythropoietin (EPO) overexpression induces a DME-like phenotype in the mouse retina

Development of an ex vivo assay to measure mitochondrial metabolism of mouse posterior eye tissue

Comparative Effects of Bevacizumab and Aflibercept on VEGF and IGF Signaling in Human Retinal Endothelial Cells Exposed to Hyperoxia and Intermittent Hypoxia

Development and Characterization of a new Mouse Model of Proliferative Diabetic Retinopathy

Exogenous Superoxide Dismutase Mimetic Without Scavenging H 2 O 2 Causes Photoreceptor Damage in a Rat Model for Oxygen-Induced Retinopathy

Response of Human Retinal Endothelial Cells (HRECs) to Small Interfering RNA (SiRNA) Silencing of Notch-1, Delta-Like Ligand 4 (Dll4), and Jagged-1 During Hyperoxia with Intermittent Hypoxia (IH).

Hydrogen Peroxide Accumulation in the Choroid During Intermittent Hypoxia Increases Risk of Severe Oxygen-Induced Retinopathy in Neonatal Rats

Retinal Protease and Collagen Responses to Increasing Numbers of Intermittent Hypoxia During Hyperoxia in a Rat Model for Oxygen-Induced Retinopathy

Mixed Arterial-Venous PO2 Levels Critical to Ocular Markers of Angiogenesis and Oxidative Stress in Neonatal Rats

Matrix Metalloproteinases in the Vitreous Cleave Prolactin to Vasoinhibins

Diabetic Retinopathy Is Associated With Increased Vascular Stability

Vasoinhibins Prevent the Diabetic Retinopathy-Associated Vascular Leakage in vivo via Protein Phosphatase 2A-Dependent eNOS Inactivation

Vasoinhibins Inhibit Vascular Leakage and Vasodilation Induced by VEGF in the Retina

Prolactin Protects Photoreceptors From Light Damage in vivo

Prolactin Decreases in the Circulation of Patients with Proliferative Diabetic Retinopathy: Relationship to Intraocular Vasoinhibins

Comparative Effects of Early Postnatal Ibuprofen and Indomethacin on VEGF, IGF-I, and GH during Rat Ocular Development

Localization of Prolactin and the Prolactin Receptor in Rat Retina

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