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ARVO Annual Meeting Abstract June 2024

Molecular and Cellular Mechanisms of Levodopa-Mediated Visual Function Rescue in Albinism

Sarah Macdonald; Eloise Keeling; Jennifer A Scott; Helen Griffiths; Andrew Lotery; J. Arjuna Ratnayaka; James Edward Self; Helena Lee

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):821.

ARVO Annual Meeting Abstract June 2023

MacuSIM: An in-vitro model of the outer retina as an experimental platform for macular disease and therapeutic trials

J. Arjuna Ratnayaka; David A Johnston; Ben Mills; Andrew J Lotery; Tracey A Newman; Savannah Amy Lynn

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4743.

ARVO Annual Meeting Abstract June 2022

Sigma-2 receptor modulators rescue POS trafficking deficits in RPE cell-based models of dry AMD

Evi Malagise; Eloise Keeling; Nicole Knezovich; Lora Waybright; Emily Watto; Anthony O Caggiano; J. Arjuna Ratnayaka; Mary E. Hamby

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3182 – F0456.

ARVO Annual Meeting Abstract July 2019

Oral human-equivalent L-DOPA/Carbidopa dosages administered during the postnatal critical period of neuroplasticity rescues retinal morphology and visual function in a mouse model of human albinism

Aida Sanchez-Bretano; Jennifer Ann Scott; Tutte Newall; Savannah Lynn; Helen Griffiths; Ahmed Salman; Andrew Lotery; J. Arjuna Ratnayaka; James Edward Self; Helena Lee

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1393.

ARVO Annual Meeting Abstract July 2019

Characterization of the retinal phenotype of the C57BL/6-c2J mouse model of human oculocutaneous albinism: implications for treatment development

Jennifer Ann Scott; Aida Sanchez-Bretano; Helen Griffiths; Jon Ward; Chiamaka Dibigbou; Flavie Soubigou; James Edward Self; Andrew Lotery; J. Arjuna Ratnayaka; Helena Lee

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):529.

ARVO Annual Meeting Abstract July 2019

Modelling Sorsby’s Fundus Dystrophy using patient-derived iPSC-RPE

Jennifer Dewing; David R. G. Christensen; Heidi Hongisto; Jennifer Scott; Ben Jenkins; Angela Jane Cree; Heli Skottman; J. Arjuna Ratnayaka; Andrew Lotery

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):424.

ARVO Annual Meeting Abstract July 2018

Lysosomal impairment in the Retinal Pigment Epithelium (RPE) - a pathway of damage in the ageing retina

Eloise Keeling; David A. Johnston; David S. Chatelet; David Tumbarello; Andrew Lotery; J. Arjuna Ratnayaka

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4487.

ARVO Annual Meeting Abstract July 2018

Subretinal Aβ injections induce a localised, early CNV phenotype in C57BL/6 mice

Savannah Lynn; Jennifer Scott; Helena helenalee100@yahoo.co.uk Lee; Roshni Desai; Tracey Newman; Angela Cree; Andrew Lotery; J. Arjuna Ratnayaka

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5827.

ARVO Annual Meeting Abstract July 2018

The contribution of common population variants to hypomorphic oculocutaneous albinism phenotypes: a novel tri-allelic TYR genotype

Chelsea Sarah Norman; Luke O'Gorman; Jane Gibson; Reuben J Pengelly; Diana Baralle; J. Arjuna Ratnayaka; Sarah Ennis; James E Self

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5784.

ARVO Annual Meeting Abstract September 2016

A mouse model to study Aβ-driven pathology in the ageing retina.

Savannah Amy Lynn; Srini Goverdhan; Rosie Munday; Jennifer Scott; Thomas Freeman; David Johnston; Andrew J Lotery; J Arjuna Ratnayaka

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6534.

ARVO Annual Meeting Abstract September 2016

A novel biosynthetic RPE-BrM (Retinal Pigment Epithelium-Bruch's Membrane) assembly suitable for retinal transplantation therapy

Andrew J Lotery; Gareth Ward; Philip Alexander; David Johnston; Anton Page; Angela Jane Cree; Atul Bhaskar; Sumeet Mahajan; Martin Grossel; J Arjuna Ratnayaka

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12)

ARVO Annual Meeting Abstract June 2015

An ex-vivo platform for manipulation and study of Retinal Pigment Epithelial (RPE) cells in long-term culture.

J Arjuna Ratnayaka; Savannah A Lynn; Helen Griffiths; Jenny Scott; Angela Cree; Andrew J Lotery

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2332.

ARVO Annual Meeting Abstract April 2014

Development of a novel bio-compatible polymer film for use as a Bruch’s membrane substitute

Gareth Ward; Heather Thomson; Philip Alexander; J. Arjuna Ratnayaka; Andrew Treharne; George Attard; Martin Grossel; Andrew Lotery; Vision Group

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2997.

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