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ARVO Annual Meeting Abstract June 2020

Increased expression of the chronic ER stress-induced transcriptional factor, ATF4 leads to glaucoma by promoting protein synthesis and ER client protein load

Ramesh Kasetti; Pinkal Patel; Prabhavathi Maddineni; Shruti Patil; Charles Kiehlbauch; J Cameron Millar; Charles Searby; Val C Sheffield; Gulab Zode

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1236. doi:

ARVO Annual Meeting Abstract June 2020

Impaired TRPV4-eNOS signaling in glaucomatous trabecular meshwork contributes to elevation of intraocular pressure

Pinkal Patel; Ramesh Kasetti; Prabhavathi Maddineni; J Cameron Millar; Yen-Lin Chen; Swapnil K Sonkusare; Gulab Zode

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2784. doi:

ARVO Annual Meeting Abstract July 2019

Activation of TRPV4 channels reduces IOP and improves outflow facility by regulating eNOS dependent NO release from the TM

Pinkal D Patel; Ramesh Kasetti; prabhavathi maddineni; J Cameron Millar; Gulab Zode

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6473. doi:

Glaucoma May 2019

Glucocorticoid Receptor Transactivation Is Required for Glucocorticoid-Induced Ocular Hypertension and Glaucoma

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Gaurang C. Patel; J. Cameron Millar; Abbot F. Clark
TAGS: glaucoma, glucocorticoid receptors, glucocorticoids, medication therapy management, mice, ocular hypertension, trans-activation (genetics), intraocular pressure, injections
Invest. Ophthalmol. Vis. Sci.. 2019; 60(6):1967-1978. doi: https://doi.org/10.1167/iovs.18-26383

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

TRPV4-mediated regulation of intraocular pressure and outflow facility in mouse model of glucocorticoid-induced ocular hypertension

Pinkal Patel; J Cameron Millar; Ramesh Kasetti; prabhavathi maddineni; Gulab Zode

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4728. doi:

ARVO Annual Meeting Abstract July 2018

Glucocorticoid-Induced Ocular Hypertension in Mice Requires Glucocorticoid Receptor Transactivation Activity

Abbot F. Clark; J Cameron Millar; Gaurang Patel

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):6037. doi:

ARVO Annual Meeting Abstract July 2018

Characterization of SHP639, a novel topical C-type natriuretic peptide analog, on intraocular pressure and aqueous humor dynamics in mice

Iok-Hou Pang; J Cameron Millar; Serene T Josiah; Anneli Savinainen

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2713. doi:

ARVO Annual Meeting Abstract July 2018

Mouse Eye Perfusion In-Vivo Versus Ex-Vivo: Influence on Aqueous Outflow Facility

J Cameron Millar; Navita N Lopez; Urmimala Raychaudhuri; Abbot F. Clark

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1655. doi:

Glaucoma April 2018

BMP and Activin Membrane Bound Inhibitor Regulates the Extracellular Matrix in the Trabecular Meshwork

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Humberto Hernandez; J. Cameron Millar; Stacy M. Curry; Abbot F. Clark; Colleen M. McDowell
TAGS: activins, extracellular matrix, mice, tissue membrane, trabecular meshwork, eye, fibronectins, ocular hypertension, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2018; 59(5):2154-2166. doi: https://doi.org/10.1167/iovs.17-23282

Includes: Supplemental Content

Glaucoma March 2018

The Role of Wnt/β-Catenin Signaling and K-Cadherin in the Regulation of Intraocular Pressure

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Hannah C. Webber; Jaclyn Y. Bermudez; J. Cameron Millar; Weiming Mao; Abbot F. Clark
TAGS: cadherins, signal transduction, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2018; 59(3):1454-1466. doi: https://doi.org/10.1167/iovs.17-21964

Includes: Supplemental Content

Glaucoma December 2017

Tissue Transglutaminase Elevates Intraocular Pressure in Mice

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Urmimala Raychaudhuri; J. Cameron Millar; Abbot F. Clark
TAGS: body tissue, eye, intraocular pressure, mice, transglutaminases
Invest. Ophthalmol. Vis. Sci.. 2017; 58(14):6197-6211. doi: https://doi.org/10.1167/iovs.17-22236

Includes: Supplemental Content

Glaucoma November 2017

Effect of Cromakalim Prodrug 1 (CKLP1) on Aqueous Humor Dynamics and Feasibility of Combination Therapy With Existing Ocular Hypotensive Agents

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Uttio Roy Chowdhury; Tommy A. Rinkoski; Cindy K. Bahler; J. Cameron Millar; Jacques A. Bertrand; Bradley H. Holman; Joseph M. Sherwood; Darryl R. Overby; Kristen L. Stoltz; Peter I. Dosa; Michael P. Fautsch
TAGS: antihypertensive agents, aqueous humor, combined modality therapy, cromakalim, eye, intraocular pressure, mice, oryctolagus cuniculus, prodrugs, perfusion
Invest. Ophthalmol. Vis. Sci.. 2017; 58(13):5731-5742. doi: https://doi.org/10.1167/iovs.17-22538

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

Anterior Chamber Versus Posterior Chamber Perfusion Does Not Influence Aqueous Outflow Facility in Living Mice as Measured by Constant Flow Infusion

J Cameron Millar; Navita Nanda Lopez; Gaurang C Patel; Tien Phan; Abbot F Clark

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1061. doi:

ARVO Annual Meeting Abstract June 2017

Glucocorticoid receptor GRβ regulates glucocorticoid-induced ocular hypertension and glaucoma in mice

Gaurang C Patel; Yang Liu; J Cameron Millar; Abbot F Clark

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):849. doi:

ARVO Annual Meeting Abstract June 2017

Tissue transglutaminase mediated ocular hypertension and effects of a small molecule crosslinking modulator

Urmimala Raychaudhuri; J Cameron Millar; Abbot F Clark

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3494. doi:

ARVO Annual Meeting Abstract June 2017

Inhibition of Transforming Growth Factor-β2 Signaling Prevents ECM Remodeling, Endoplasmic Reticulum Stress and Ocular Hypertension in Steroid-induced Glaucoma

Ramesh Kasetti; Prabhavathi Maddineni; Pinkal Patel; J Cameron Millar; Tien Phan; Charles C Searby; Abbot F Clark; Val Sheffield; Gulab Zode

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4603. doi:

Glaucoma November 2016

Expression of Mutant Myocilin Induces Abnormal Intracellular Accumulation of Selected Extracellular Matrix Proteins in the Trabecular Meshwork

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Ramesh B. Kasetti; Tien N. Phan; J. Cameron Millar; Gulab S. Zode
TAGS: myoc gene, proteins, mice, fibronectins, extracellular matrix proteins, trabecular meshwork
Invest. Ophthalmol. Vis. Sci.. 2016; 57(14):6058-6069. doi: https://doi.org/10.1167/iovs.16-19610

ARVO Annual Meeting Abstract September 2016

PRIMARY OPEN ANGLE GLAUCOMA AND ALZHEIMER’S DISEASE: IS THERE AN ASSOCIATION IN 5XFAD MICE?

J Cameron Millar; Hannah C. Webber; Tien Phan; Sandra Neubauer; Abbot F Clark

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2543. doi:

ARVO Annual Meeting Abstract September 2016

Tissue transglutaminase causes intraocular pressure elevation in mice

Urmimala Raychaudhuri; J Cameron Millar; Colleen M McDowell; Abbot F Clark

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4683. doi:

ARVO Annual Meeting Abstract September 2016

Periocular injections of dexamethasone reduce outflow facility and elevate intraocular pressure in C57 mice.

Tien Phan; Ramesh Kasetti; Amit Sope; J Cameron Millar; Abbot F Clark; Gulab Zode

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6450. doi:

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Increased expression of the chronic ER stress-induced transcriptional factor, ATF4 leads to glaucoma by promoting protein synthesis and ER client protein load

Impaired TRPV4-eNOS signaling in glaucomatous trabecular meshwork contributes to elevation of intraocular pressure

Activation of TRPV4 channels reduces IOP and improves outflow facility by regulating eNOS dependent NO release from the TM

Glucocorticoid Receptor Transactivation Is Required for Glucocorticoid-Induced Ocular Hypertension and Glaucoma

TRPV4-mediated regulation of intraocular pressure and outflow facility in mouse model of glucocorticoid-induced ocular hypertension

Glucocorticoid-Induced Ocular Hypertension in Mice Requires Glucocorticoid Receptor Transactivation Activity

Characterization of SHP639, a novel topical C-type natriuretic peptide analog, on intraocular pressure and aqueous humor dynamics in mice

Mouse Eye Perfusion In-Vivo Versus Ex-Vivo: Influence on Aqueous Outflow Facility

BMP and Activin Membrane Bound Inhibitor Regulates the Extracellular Matrix in the Trabecular Meshwork

The Role of Wnt/β-Catenin Signaling and K-Cadherin in the Regulation of Intraocular Pressure

Tissue Transglutaminase Elevates Intraocular Pressure in Mice

Effect of Cromakalim Prodrug 1 (CKLP1) on Aqueous Humor Dynamics and Feasibility of Combination Therapy With Existing Ocular Hypotensive Agents

Anterior Chamber Versus Posterior Chamber Perfusion Does Not Influence Aqueous Outflow Facility in Living Mice as Measured by Constant Flow Infusion

Glucocorticoid receptor GRβ regulates glucocorticoid-induced ocular hypertension and glaucoma in mice

Tissue transglutaminase mediated ocular hypertension and effects of a small molecule crosslinking modulator

Inhibition of Transforming Growth Factor-β2 Signaling Prevents ECM Remodeling, Endoplasmic Reticulum Stress and Ocular Hypertension in Steroid-induced Glaucoma

Expression of Mutant Myocilin Induces Abnormal Intracellular Accumulation of Selected Extracellular Matrix Proteins in the Trabecular Meshwork

PRIMARY OPEN ANGLE GLAUCOMA AND ALZHEIMER’S DISEASE: IS THERE AN ASSOCIATION IN 5XFAD MICE?

Tissue transglutaminase causes intraocular pressure elevation in mice

Periocular injections of dexamethasone reduce outflow facility and elevate intraocular pressure in C57 mice.

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