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Physiology and Pharmacology September 2018

IOP, IOP Transient Impulse, Ocular Perfusion Pressure, and Mean Arterial Pressure Relationships in Nonhuman Primates Instrumented With Telemetry

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John E. Markert; Jessica V. Jasien; Daniel C. Turner; Carrie Huisingh; Christopher A. Girkin; J. Crawford Downs
TAGS: perfusion, primates, telemetry, eye, intraocular pressure, mean arterial pressure, impulse
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4496-4505. doi: 10.1167/iovs.18-23802

Includes: Multimedia, Supplemental Content

ARVO Annual Meeting Abstract July 2018

Variation in the Three-Dimensional Histomorphometry of the Normal Human Optic Nerve Head with Elevated IOP, Age, and Race

Christopher A Girkin; J Crawford C Downs; Hongli Yang; Brandon Smith; Juan Reynaud; Claude F Burgoyne; Massimo Antonio Fazio

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1215. doi:

ARVO Annual Meeting Abstract July 2018

Intraocular Pressure and Intracranial Pressure Measurement with Continuous Wireless Telemetry to Quantify Translaminar Pressure Difference in Nonhuman Primates

Jessica V Jasien; Brian C Samuels; James M Johnston; J Crawford C Downs

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3023. doi:

Glaucoma June 2018

A Novel Tree Shrew ( Tupaia belangeri ) Model of Glaucoma

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Brian C. Samuels; John T. Siegwart; Wenjie Zhan; Lisa Hethcox; Melissa Chimento; Ryan Whitley; J. Crawford Downs; Christopher A. Girkin
TAGS: glaucoma, animal model, tupaia, tupaiidae, diagnostic imaging, eye, intraocular pressure, retinal nerve fiber layer
Invest. Ophthalmol. Vis. Sci.. 2018; 59(7):3136-3143. doi: 10.1167/iovs.18-24261

Glaucoma December 2017

The Magnitude and Time Course of IOP Change in Response to Body Position Change in Nonhuman Primates Measured Using Continuous IOP Telemetry

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Daniel C. Turner; Brian C. Samuels; Carrie Huisingh; Christopher A. Girkin; J. Crawford Downs
TAGS: primates, telemetry, time factors, eye, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2017; 58(14):6232-6240. doi: 10.1167/iovs.17-22858

Glaucoma July 2017

Variation in the Three-Dimensional Histomorphometry of the Normal Human Optic Nerve Head With Age and Race: Lamina Cribrosa and Peripapillary Scleral Thickness and Position

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Christopher A. Girkin; Massimo A. Fazio; Hongli Yang; Juan Reynaud; Claude F. Burgoyne; Brandon Smith; Lan Wang; J. Crawford Downs
TAGS: optic disk, racial group, reconstructive surgical procedures, body tissue, eye, sclera, cribriform plate, donors
Invest. Ophthalmol. Vis. Sci.. 2017; 58(9):3759-3769. doi: 10.1167/iovs.17-21842

Includes: Multimedia, Supplemental Content

Clinical and Epidemiologic Research June 2017

The Magnitude of Hypotony and Time Course of Intraocular Pressure Recovery Following Anterior Chamber Cannulation in Nonhuman Primates

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Jessica V. Jasien; Carrie Huisingh; Christopher A. Girkin; J. Crawford Downs
TAGS: anterior chamber of eye, catheterization, needle device, primates, recovery of function, time factors, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):3225-3230. doi: 10.1167/iovs.17-21833

ARVO Annual Meeting Abstract June 2017

IOP Asymmetry in Nonhuman Primates (NHPs) Measured with Continuous Telemetry

Jessica V Jasien; Daniel Turner; Jeffrey S Morris; Christopher A Girkin; J Crawford C Downs

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3408. doi:

ARVO Annual Meeting Abstract June 2017

The Relationship between IOP, IOP Transient Impulse, Ocular Perfusion Pressure (OPP), and Average Blood Pressure (BP) in Nonhuman Primates (NHP) Instrumented with Telemetry

John Markert; Jessica V Jasien; Daniel Turner; Christopher A Girkin; J Crawford C Downs

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5323. doi:

ARVO Annual Meeting Abstract June 2017

Testing and Validation of a New IOP Telemetry Sensor Suitable for Implantation Directly into the Anterior Chamber

J Crawford C Downs; Christopher A Girkin; Brian C Samuels

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1598. doi:

ARVO Annual Meeting Abstract June 2017

Eye-Specific Finite Element Modeling of Human Optic Nerve Head (ONH) Biomechanics

Kapil Krishnan; Vincent Libertiaux; Rafael Grytz; Christopher A Girkin; J Crawford C Downs

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2457. doi:

ARVO Annual Meeting Abstract June 2017

Incorporating Realistic Anisotropic and Heterogeneous Material Properties Into Eye-Specific Multi-Scale Models of the Human Optic Nerve Head

Rafael Grytz; Kapil Krishnan; Vincent Libertiaux; Christopher A Girkin; J Crawford C Downs

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2458. doi:

ARVO Annual Meeting Abstract June 2017

The Relationship Between Ocular Pulse Amplitude (OPA) and Arterial Pulse Pressure

Daniel Turner; Christopher A Girkin; J Crawford C Downs

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5322. doi:

ARVO Annual Meeting Abstract September 2016

Real-time In Vivo 2-D Deformations of the Optic Nerve Head Using OCT Imaging

Massimo Antonio Fazio; Daniel Turner; Christopher A Girkin; J Crawford Downs; Luigi Bruno

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

ARVO Annual Meeting Abstract September 2016

A Pilot Study for the Initial Validation of a Tree Shrew Model of Glaucoma

Brian C Samuels; Christopher A Girkin; Lisa Hethcox; J Crawford C Downs; Wenjie Zhan

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3572. doi:

ARVO Annual Meeting Abstract September 2016

IOP Elevations Associated with Eye Rubbing

Daniel Turner; Christopher A Girkin; J Crawford C Downs

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6433. doi:

ARVO Annual Meeting Abstract September 2016

Evidence for the "White Coat Effect” on IOP Measured Using Continuous IOP Telemetry in Nonhuman Primates

J Crawford C Downs; Daniel Turner; Christopher A Girkin

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6466. doi:

ARVO Annual Meeting Abstract September 2016

Comparison of the Effects of Injectable and Inhalant Anesthesia on IOP in Nonhuman Primates as Measured with Continuous IOP Telemetry

Jessica V Jasien; Lisa Hethcox; Daniel Turner; Christopher A Girkin; J Crawford C Downs

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

Glaucoma December 2015

Physical Factors Affecting Outflow Facility Measurements in Mice

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Alexandra Boussommier-Calleja; Guorong Li; Amanda Wilson; Tal Ziskind; Oana Elena Scinteie; Nicole E. Ashpole; Joseph M. Sherwood; Sina Farsiu; Pratap Challa; Pedro Gonzalez; J. Crawford Downs; C. Ross Ethier; W. Daniel Stamer; Darryl R. Overby
TAGS: perfusion, body temperature, eye, iris, mice, temperature, immune reconstitution inflammatory syndrome
Invest. Ophthalmol. Vis. Sci.. 2015; 56(13):8331-8339. doi: 10.1167/iovs.15-17106

Includes: Supplemental Content

Glaucoma December 2015

High-Magnitude and/or High-Frequency Mechanical Strain Promotes Peripapillary Scleral Myofibroblast Differentiation

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Jing Qu; Huaping Chen; Lanyan Zhu; Namasivayam Ambalavanan; Christopher A. Girkin; Joanne E. Murphy-Ullrich; J. Crawford Downs; Yong Zhou
TAGS: fibroblasts, collagen, gel, rna, messenger, eye, proteins, sclera, myofibroblast
Invest. Ophthalmol. Vis. Sci.. 2015; 56(13):7821-7830. doi: 10.1167/iovs.15-17848

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IOP, IOP Transient Impulse, Ocular Perfusion Pressure, and Mean Arterial Pressure Relationships in Nonhuman Primates Instrumented With Telemetry

Variation in the Three-Dimensional Histomorphometry of the Normal Human Optic Nerve Head with Elevated IOP, Age, and Race

Intraocular Pressure and Intracranial Pressure Measurement with Continuous Wireless Telemetry to Quantify Translaminar Pressure Difference in Nonhuman Primates

A Novel Tree Shrew ( Tupaia belangeri ) Model of Glaucoma

The Magnitude and Time Course of IOP Change in Response to Body Position Change in Nonhuman Primates Measured Using Continuous IOP Telemetry

Variation in the Three-Dimensional Histomorphometry of the Normal Human Optic Nerve Head With Age and Race: Lamina Cribrosa and Peripapillary Scleral Thickness and Position

The Magnitude of Hypotony and Time Course of Intraocular Pressure Recovery Following Anterior Chamber Cannulation in Nonhuman Primates

IOP Asymmetry in Nonhuman Primates (NHPs) Measured with Continuous Telemetry

The Relationship between IOP, IOP Transient Impulse, Ocular Perfusion Pressure (OPP), and Average Blood Pressure (BP) in Nonhuman Primates (NHP) Instrumented with Telemetry

Testing and Validation of a New IOP Telemetry Sensor Suitable for Implantation Directly into the Anterior Chamber

Eye-Specific Finite Element Modeling of Human Optic Nerve Head (ONH) Biomechanics

Incorporating Realistic Anisotropic and Heterogeneous Material Properties Into Eye-Specific Multi-Scale Models of the Human Optic Nerve Head

The Relationship Between Ocular Pulse Amplitude (OPA) and Arterial Pulse Pressure

Real-time In Vivo 2-D Deformations of the Optic Nerve Head Using OCT Imaging

A Pilot Study for the Initial Validation of a Tree Shrew Model of Glaucoma

IOP Elevations Associated with Eye Rubbing

Evidence for the "White Coat Effect” on IOP Measured Using Continuous IOP Telemetry in Nonhuman Primates

Comparison of the Effects of Injectable and Inhalant Anesthesia on IOP in Nonhuman Primates as Measured with Continuous IOP Telemetry

Physical Factors Affecting Outflow Facility Measurements in Mice

High-Magnitude and/or High-Frequency Mechanical Strain Promotes Peripapillary Scleral Myofibroblast Differentiation

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