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Glaucoma October 2019

The Relationship Between Scleral Strain Change and Differential Cumulative Intraocular Pressure Exposure in the Nonhuman Primate Chronic Ocular Hypertension Model

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Massimo A. Fazio; Michael J. A. Girard; Wonyul Lee; Jeffrey S. Morris; Claude F. Burgoyne; J. Crawford Downs
TAGS: eye, intraocular pressure, ocular hypertension, sclera, primates
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4141-4150. doi: 10.1167/iovs.19-27060

Clinical and Epidemiologic Research September 2019

Effect of Anesthesia on Intraocular Pressure Measured With Continuous Wireless Telemetry in Nonhuman Primates

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Jessica V. Jasien; Christopher A. Girkin; J. Crawford Downs
TAGS: intraocular pressure, primates, telemetry, wireless technology, ketamine, dexmedetomidine, xylazine
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3830-3834. doi: 10.1167/iovs.19-27758

ARVO Annual Meeting Abstract July 2019

Effect of Body Position on IOP, Intracranial Pressure and the Translaminar Pressure Difference Measured with Continuous Wireless Telemetry in Nonhuman Primates

Jessica V Jasien; Brian C Samuels; James M Johnston; J Crawford C Downs

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3913. doi:

Glaucoma June 2019

Transient Intraocular Pressure Fluctuations: Source, Magnitude, Frequency, and Associated Mechanical Energy

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Daniel C. Turner; Anna M. Edmiston; Ye Emma Zohner; Kevin J. Byrne; William P. Seigfreid; Christopher A. Girkin; Jeffrey S. Morris; J. Crawford Downs
TAGS: intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2019; 60(7):2572-2582. doi: 10.1167/iovs.19-26600

Includes: Multimedia, Supplemental Content

Physiology and Pharmacology September 2018

IOP, IOP Transient Impulse, Ocular Perfusion Pressure, and Mean Arterial Pressure Relationships in Nonhuman Primates Instrumented With Telemetry

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John E. Markert; Jessica V. Jasien; Daniel C. Turner; Carrie Huisingh; Christopher A. Girkin; J. Crawford Downs
TAGS: perfusion, primates, telemetry, eye, intraocular pressure, mean arterial pressure, impulse
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4496-4505. doi: 10.1167/iovs.18-23802

Includes: Multimedia, Supplemental Content

ARVO Annual Meeting Abstract July 2018

Variation in the Three-Dimensional Histomorphometry of the Normal Human Optic Nerve Head with Elevated IOP, Age, and Race

Christopher A Girkin; J Crawford C Downs; Hongli Yang; Brandon Smith; Juan Reynaud; Claude F Burgoyne; Massimo Antonio Fazio

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1215. doi:

ARVO Annual Meeting Abstract July 2018

Intraocular Pressure and Intracranial Pressure Measurement with Continuous Wireless Telemetry to Quantify Translaminar Pressure Difference in Nonhuman Primates

Jessica V Jasien; Brian C Samuels; James M Johnston; J Crawford C Downs

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3023. doi:

Glaucoma June 2018

A Novel Tree Shrew ( Tupaia belangeri ) Model of Glaucoma

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Brian C. Samuels; John T. Siegwart; Wenjie Zhan; Lisa Hethcox; Melissa Chimento; Ryan Whitley; J. Crawford Downs; Christopher A. Girkin
TAGS: glaucoma, animal model, tupaia, tupaiidae, diagnostic imaging, eye, intraocular pressure, retinal nerve fiber layer
Invest. Ophthalmol. Vis. Sci.. 2018; 59(7):3136-3143. doi: 10.1167/iovs.18-24261

Glaucoma December 2017

The Magnitude and Time Course of IOP Change in Response to Body Position Change in Nonhuman Primates Measured Using Continuous IOP Telemetry

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Daniel C. Turner; Brian C. Samuels; Carrie Huisingh; Christopher A. Girkin; J. Crawford Downs
TAGS: primates, telemetry, time factors, eye, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2017; 58(14):6232-6240. doi: 10.1167/iovs.17-22858

Glaucoma July 2017

Variation in the Three-Dimensional Histomorphometry of the Normal Human Optic Nerve Head With Age and Race: Lamina Cribrosa and Peripapillary Scleral Thickness and Position

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Christopher A. Girkin; Massimo A. Fazio; Hongli Yang; Juan Reynaud; Claude F. Burgoyne; Brandon Smith; Lan Wang; J. Crawford Downs
TAGS: optic disk, racial group, reconstructive surgical procedures, body tissue, eye, sclera, cribriform plate, donors
Invest. Ophthalmol. Vis. Sci.. 2017; 58(9):3759-3769. doi: 10.1167/iovs.17-21842

Includes: Multimedia, Supplemental Content

Clinical and Epidemiologic Research June 2017

The Magnitude of Hypotony and Time Course of Intraocular Pressure Recovery Following Anterior Chamber Cannulation in Nonhuman Primates

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Jessica V. Jasien; Carrie Huisingh; Christopher A. Girkin; J. Crawford Downs
TAGS: anterior chamber of eye, catheterization, needle device, primates, recovery of function, time factors, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):3225-3230. doi: 10.1167/iovs.17-21833

ARVO Annual Meeting Abstract June 2017

IOP Asymmetry in Nonhuman Primates (NHPs) Measured with Continuous Telemetry

Jessica V Jasien; Daniel Turner; Jeffrey S Morris; Christopher A Girkin; J Crawford C Downs

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3408. doi:

ARVO Annual Meeting Abstract June 2017

The Relationship between IOP, IOP Transient Impulse, Ocular Perfusion Pressure (OPP), and Average Blood Pressure (BP) in Nonhuman Primates (NHP) Instrumented with Telemetry

John Markert; Jessica V Jasien; Daniel Turner; Christopher A Girkin; J Crawford C Downs

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5323. doi:

ARVO Annual Meeting Abstract June 2017

Testing and Validation of a New IOP Telemetry Sensor Suitable for Implantation Directly into the Anterior Chamber

J Crawford C Downs; Christopher A Girkin; Brian C Samuels

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1598. doi:

ARVO Annual Meeting Abstract June 2017

Eye-Specific Finite Element Modeling of Human Optic Nerve Head (ONH) Biomechanics

Kapil Krishnan; Vincent Libertiaux; Rafael Grytz; Christopher A Girkin; J Crawford C Downs

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2457. doi:

ARVO Annual Meeting Abstract June 2017

Incorporating Realistic Anisotropic and Heterogeneous Material Properties Into Eye-Specific Multi-Scale Models of the Human Optic Nerve Head

Rafael Grytz; Kapil Krishnan; Vincent Libertiaux; Christopher A Girkin; J Crawford C Downs

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2458. doi:

ARVO Annual Meeting Abstract June 2017

The Relationship Between Ocular Pulse Amplitude (OPA) and Arterial Pulse Pressure

Daniel Turner; Christopher A Girkin; J Crawford C Downs

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5322. doi:

ARVO Annual Meeting Abstract September 2016

Real-time In Vivo 2-D Deformations of the Optic Nerve Head Using OCT Imaging

Massimo Antonio Fazio; Daniel Turner; Christopher A Girkin; J Crawford Downs; Luigi Bruno

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

ARVO Annual Meeting Abstract September 2016

A Pilot Study for the Initial Validation of a Tree Shrew Model of Glaucoma

Brian C Samuels; Christopher A Girkin; Lisa Hethcox; J Crawford C Downs; Wenjie Zhan

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3572. doi:

ARVO Annual Meeting Abstract September 2016

IOP Elevations Associated with Eye Rubbing

Daniel Turner; Christopher A Girkin; J Crawford C Downs

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6433. doi:

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The Relationship Between Scleral Strain Change and Differential Cumulative Intraocular Pressure Exposure in the Nonhuman Primate Chronic Ocular Hypertension Model

Effect of Anesthesia on Intraocular Pressure Measured With Continuous Wireless Telemetry in Nonhuman Primates

Effect of Body Position on IOP, Intracranial Pressure and the Translaminar Pressure Difference Measured with Continuous Wireless Telemetry in Nonhuman Primates

Transient Intraocular Pressure Fluctuations: Source, Magnitude, Frequency, and Associated Mechanical Energy

IOP, IOP Transient Impulse, Ocular Perfusion Pressure, and Mean Arterial Pressure Relationships in Nonhuman Primates Instrumented With Telemetry

Variation in the Three-Dimensional Histomorphometry of the Normal Human Optic Nerve Head with Elevated IOP, Age, and Race

Intraocular Pressure and Intracranial Pressure Measurement with Continuous Wireless Telemetry to Quantify Translaminar Pressure Difference in Nonhuman Primates

A Novel Tree Shrew ( Tupaia belangeri ) Model of Glaucoma

The Magnitude and Time Course of IOP Change in Response to Body Position Change in Nonhuman Primates Measured Using Continuous IOP Telemetry

Variation in the Three-Dimensional Histomorphometry of the Normal Human Optic Nerve Head With Age and Race: Lamina Cribrosa and Peripapillary Scleral Thickness and Position

The Magnitude of Hypotony and Time Course of Intraocular Pressure Recovery Following Anterior Chamber Cannulation in Nonhuman Primates

IOP Asymmetry in Nonhuman Primates (NHPs) Measured with Continuous Telemetry

The Relationship between IOP, IOP Transient Impulse, Ocular Perfusion Pressure (OPP), and Average Blood Pressure (BP) in Nonhuman Primates (NHP) Instrumented with Telemetry

Testing and Validation of a New IOP Telemetry Sensor Suitable for Implantation Directly into the Anterior Chamber

Eye-Specific Finite Element Modeling of Human Optic Nerve Head (ONH) Biomechanics

Incorporating Realistic Anisotropic and Heterogeneous Material Properties Into Eye-Specific Multi-Scale Models of the Human Optic Nerve Head

The Relationship Between Ocular Pulse Amplitude (OPA) and Arterial Pulse Pressure

Real-time In Vivo 2-D Deformations of the Optic Nerve Head Using OCT Imaging

A Pilot Study for the Initial Validation of a Tree Shrew Model of Glaucoma

IOP Elevations Associated with Eye Rubbing

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